hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12665.1
Complex Portal: CPX-20935
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PRDX1 | Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1) | 5 | UniProt NCBI |
| PRDX4 | Peroxiredoxin-4 (EC 1.11.1.24) (Antioxidant enzyme AOE372) (AOE37-2) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372) (Thioredoxin-dependent peroxiredoxin 4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP15 | 0.000969601127591 | 1.0 | PRDX1 PRDX4 | Selenium micronutrient network |
| GO:0008379 | 0.0028092043205 | 1.0 | PRDX1 PRDX4 | thioredoxin peroxidase activity |
| GO:0051920 | 0.0028092043205 | 1.0 | PRDX1 PRDX4 | peroxiredoxin activity |
| GO:0140824 | 0.0028092043205 | 1.0 | PRDX1 PRDX4 | thioredoxin-dependent peroxiredoxin activity |
| CORUM:3151 | 0.0499419797295 | 0.5 | PRDX1 | Sulphiredoxin-peroxiredoxin complex |
| CORUM:6675 | 0.0499419797295 | 0.5 | PRDX1 | PI4K2A-PRDX1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PRDX4 | PRDX1 | 0.976 | 0.258 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PRDX1 | huMAP3_04241.1 huMAP3_12483.1 huMAP3_12665.1 huMAP3_12666.1 huMAP3_14188.1 huMAP3_15271.1 |
| PRDX4 | huMAP3_04241.1 huMAP3_11980.1 huMAP3_12665.1 huMAP3_12666.1 |