hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12668.1
Complex Portal: CPX-13812
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LAT | Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38) | 5 | UniProt NCBI |
| TP53I11 | Tumor protein p53-inducible protein 11 (p53-induced gene 11 protein) | 2 | UniProt NCBI |
| TRAM2 | Translocating chain-associated membrane protein 2 | 4 | UniProt NCBI |
| TSPAN8 | Tetraspanin-8 (Tspan-8) (Transmembrane 4 superfamily member 3) (Tumor-associated antigen CO-029) | 5 | UniProt NCBI |
| ZDHHC20 | Palmitoyltransferase ZDHHC20 (EC 2.3.1.225) (Acyltransferase ZDHHC20) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 20) (DHHC20) (Zinc finger DHHC domain-containing protein 20) | 5 | UniProt NCBI |
| SLC30A3 | Probable proton-coupled zinc antiporter SLC30A3 (Solute carrier family 30 member 3) (Zinc transporter 3) (ZnT-3) | 5 | UniProt NCBI |
| ATP9B | Probable phospholipid-transporting ATPase IIB (EC 7.6.2.1) (ATPase class II type 9B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2909 | 0.0499958217778 | 0.142857142857 | LAT | PLC-gamma-2-Syk-LAT-FcR-gamma complex |
| CORUM:2913 | 0.0499958217778 | 0.142857142857 | LAT | PLC-gamma-2-LAT complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TP53I11 | TSPAN8 | 0.999 | 0.082 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ZDHHC20 | TSPAN8 | 0.998 | 0.132 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ZDHHC20 | LAT | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SLC30A3 | TSPAN8 | 0.996 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ATP9B | TSPAN8 | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TRAM2 | TP53I11 | 0.912 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only | |
| SLC30A3 | ATP9B | 0.892 | bioplex3_WMM WMM_only | ||
| TP53I11 | ATP9B | 0.892 | 0.054 | bioplex3_WMM WMM_only | |
| SLC30A3 | ZDHHC20 | 0.634 | bioplex3_WMM WMM_only | ||
| SLC30A3 | TP53I11 | 0.405 | bioplex3_WMM WMM_only | ||
| ZDHHC20 | ATP9B | 0.388 | 0.068 | bioplex3_WMM WMM_only | |
| ZDHHC20 | TP53I11 | 0.263 | 0.056 | bioplex3_WMM gupta_WMM WMM_only |
Related Complexes