hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12681.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UQCC5 | Ubiquinol-cytochrome c reductase complex assembly factor 5 (Small integral membrane protein 4) | 4 | UniProt NCBI |
| PROC | Vitamin K-dependent protein C (EC 3.4.21.69) (Anticoagulant protein C) (Autoprothrombin IIA) (Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide] | 5 | UniProt NCBI |
| MGAT2 | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.143) (Beta-1,2-N-acetylglucosaminyltransferase II) (GlcNAc-T II) (GNT-II) (Mannoside acetylglucosaminyltransferase 2) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-4793952 | 0.0498224659464 | 0.333333333333 | MGAT2 | Defective MGAT2 causes CDG-2a |
| CORUM:6112 | 0.0499402709677 | 0.333333333333 | MGAT2 | DGAT2-MGAT2 complex |
| CORUM:6622 | 0.0499402709677 | 0.333333333333 | MGAT2 | MGAT2-SLC35A3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MGAT2 | PROC | 0.916 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PROC | UQCC5 | 0.864 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MGAT2 | UQCC5 | 0.142 | 0.16 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes