hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12683.1
Complex Portal: CPX-15724
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| WDR41 | WD repeat-containing protein 41 | 5 | UniProt NCBI |
| IMMP1L | Mitochondrial inner membrane protease subunit 1 (EC 3.4.21.-) (IMP1-like protein) | 3 | UniProt NCBI |
| TMEM248 | Transmembrane protein 248 | 5 | UniProt NCBI |
| TSPAN5 | Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane 4 superfamily member 9) | 5 | UniProt NCBI |
| C9orf72 | Guanine nucleotide exchange factor C9orf72 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7063 | 4.09448956317e-05 | 0.4 | WDR41 C9orf72 | C9orf72-SMCR8-WDR41 complex |
| CORUM:7065 | 0.000286457379015 | 0.4 | WDR41 C9orf72 | WDR41-(C9orf72-SMCR8)-(FIP200-ULK1-ATG13-ATG101) complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TSPAN5 | TMEM248 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TSPAN5 | IMMP1L | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TSPAN5 | WDR41 | 0.941 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| C9orf72 | WDR41 | 0.891 | 0.136 | bioplex3_HEK293 bioplex3_WMM gupta_WMM WMM_only | |
| TMEM248 | IMMP1L | 0.377 | bioplex_WMM bioplex3_WMM WMM_only | ||
| IMMP1L | WDR41 | 0.242 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TMEM248 | WDR41 | 0.224 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes