hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12694.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADSS1 | Adenylosuccinate synthetase isozyme 1 (AMPSase 1) (AdSS 1) (EC 6.3.4.4) (Adenylosuccinate synthetase, basic isozyme) (Adenylosuccinate synthetase, muscle isozyme) (M-type adenylosuccinate synthetase) (Adenylosuccinate synthetase-like 1) (AdSSL1) (IMP--aspartate ligase 1) | 5 | UniProt NCBI |
| SMYD1 | Histone-lysine N-methyltransferase SMYD1 (EC 2.1.1.354) (SET and MYND domain-containing protein 1) | 5 | UniProt NCBI |
| ADSS2 | Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00250 | 0.000354497763776 | 0.666666666667 | ADSS1 ADSS2 | Alanine, aspartate and glutamate metabolism |
| REAC:R-HSA-73817 | 0.000374861161166 | 0.666666666667 | ADSS1 ADSS2 | Purine ribonucleoside monophosphate biosynthesis |
| REAC:R-HSA-8956320 | 0.000620139908703 | 0.666666666667 | ADSS1 ADSS2 | Nucleotide biosynthesis |
| GO:0004019 | 0.00140460216025 | 0.666666666667 | ADSS1 ADSS2 | adenylosuccinate synthase activity |
| KEGG:01232 | 0.00183782119288 | 0.666666666667 | ADSS1 ADSS2 | Nucleotide metabolism |
| KEGG:00230 | 0.00361241039138 | 0.666666666667 | ADSS1 ADSS2 | Purine metabolism |
| KEGG:01240 | 0.00676143238566 | 0.666666666667 | ADSS1 ADSS2 | Biosynthesis of cofactors |
| KEGG:01100 | 0.0189521995452 | 1.0 | ADSS1 ADSS2 SMYD1 | Metabolic pathways |
| REAC:R-HSA-15869 | 0.019882541548 | 0.666666666667 | ADSS1 ADSS2 | Metabolism of nucleotides |
| GO:0044208 | 0.0294899169624 | 0.666666666667 | ADSS1 ADSS2 | 'de novo' AMP biosynthetic process |
| GO:0006167 | 0.0393180950424 | 0.666666666667 | ADSS1 ADSS2 | AMP biosynthetic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ADSS1 | ADSS2 | 0.999 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SMYD1 | ADSS2 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes