hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12695.1
Complex Portal: CPX-14847
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHP2 | Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520) | 5 | UniProt NCBI |
| CENPS | Centromere protein S (CENP-S) (Apoptosis-inducing TAF9-like domain-containing protein 1) (FANCM-associated histone fold protein 1) (FANCM-interacting histone fold protein 1) (Fanconi anemia-associated polypeptide of 16 kDa) | 5 | UniProt NCBI |
| CFAP68 | Cilia- and flagella-associated protein 68 | 5 | UniProt NCBI |
| CENPX | Centromere protein X (CENP-X) (FANCM-associated histone fold protein 2) (FANCM-interacting histone fold protein 2) (Fanconi anemia-associated polypeptide of 10 kDa) (Retinoic acid-inducible gene D9 protein homolog) (Stimulated by retinoic acid gene 13 protein homolog) | 5 | UniProt NCBI |
| FAAP24 | Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0071821 | 3.84440695359e-06 | 0.6 | CENPS FAAP24 CENPX | FANCM-MHF complex |
| CORUM:6145 | 1.36501667663e-05 | 0.4 | CENPS CENPX | CENP-S-X complex |
| KEGG:03460 | 1.71122661794e-05 | 0.6 | CENPS FAAP24 CENPX | Fanconi anemia pathway |
| REAC:R-HSA-6783310 | 2.03584684634e-05 | 0.6 | CENPS FAAP24 CENPX | Fanconi Anemia Pathway |
| CORUM:6146 | 8.18785830799e-05 | 0.4 | CENPS CENPX | CENP-T-W-S-X heterotetramer complex |
| GO:0043240 | 0.000211268761872 | 0.6 | CENPS FAAP24 CENPX | Fanconi anaemia nuclear complex |
| WP:WP4946 | 0.00027954510039 | 0.6 | CENPS FAAP24 CENPX | DNA repair pathways full network |
| GO:0036297 | 0.00522817157061 | 0.6 | CENPS FAAP24 CENPX | interstrand cross-link repair |
| REAC:R-HSA-73894 | 0.014302073064 | 0.6 | CENPS FAAP24 CENPX | DNA Repair |
| REAC:R-HSA-606279 | 0.0275944536635 | 0.4 | CENPS CENPX | Deposition of new CENPA-containing nucleosomes at the centromere |
| REAC:R-HSA-774815 | 0.0275944536635 | 0.4 | CENPS CENPX | Nucleosome assembly |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CENPX | CENPS | 0.998 | 0.186 | hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CFAP68 | CENPS | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CENPX | FAAP24 | 0.982 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CENPS | FAAP24 | 0.922 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CENPX | CHP2 | 0.915 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes