hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12707.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EXD2 | Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) | 5 | UniProt NCBI |
| GRAMD2A | GRAM domain-containing protein 2A | 5 | UniProt NCBI |
| GRAMD1B | Protein Aster-B (GRAM domain-containing protein 1B) | 5 | UniProt NCBI |
| TMX1 | Thioredoxin-related transmembrane protein 1 (Protein disulfide-isomerase TMX1) (EC 5.3.4.1) (Thioredoxin domain-containing protein 1) (Transmembrane Trx-related protein) | 5 | UniProt NCBI |
| KCNMB4 | Calcium-activated potassium channel subunit beta-4 (BK channel subunit beta-4) (BKbeta4) (Hbeta4) (Calcium-activated potassium channel, subfamily M subunit beta-4) (Charybdotoxin receptor subunit beta-4) (K(VCA)beta-4) (Maxi K channel subunit beta-4) (Slo-beta-4) | 5 | UniProt NCBI |
| GRAMD2B | GRAM domain-containing protein 2B (HCV NS3-transactivated protein 2) | 5 | UniProt NCBI |
| SNN | Stannin (AG8_1) | 5 | UniProt NCBI |
| GRAMD1C | Protein Aster-C (GRAM domain-containing protein 1C) | 4 | UniProt NCBI |
| EFCAB14 | EF-hand calcium-binding domain-containing protein 14 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0044232 | 0.000488457397695 | 0.444444444444 | GRAMD2A GRAMD1B GRAMD1C TMX1 | organelle membrane contact site |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GRAMD1C | GRAMD1B | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| GRAMD2B | GRAMD1C | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| GRAMD2B | GRAMD1B | 0.999 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| SNN | TMX1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| EFCAB14 | GRAMD2B | 0.998 | 0.1 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| EXD2 | GRAMD2B | 0.997 | 0.048 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TMX1 | GRAMD1B | 0.983 | 0.102 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| GRAMD2B | TMX1 | 0.98 | 0.09 | bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| KCNMB4 | TMX1 | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| GRAMD2A | GRAMD2B | 0.977 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GRAMD2A | GRAMD1B | 0.976 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| EFCAB14 | GRAMD1B | 0.936 | 0.136 | bioplex_WMM bioplex3_WMM WMM_only |
| EFCAB14 | GRAMD1C | 0.936 | bioplex_WMM bioplex3_WMM WMM_only | |
| GRAMD1C | TMX1 | 0.914 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| GRAMD2B | SNN | 0.902 | bioplex3_WMM WMM_only | |
| EFCAB14 | GRAMD2A | 0.902 | bioplex3_WMM WMM_only | |
| EFCAB14 | EXD2 | 0.857 | 0.098 | bioplex_WMM bioplex3_WMM WMM_only |
| EXD2 | GRAMD1B | 0.652 | 0.058 | bioplex_WMM bioplex3_WMM WMM_only |
| GRAMD2A | GRAMD1C | 0.596 | bioplex3_WMM WMM_only | |
| EXD2 | GRAMD1C | 0.463 | bioplex_WMM bioplex3_WMM WMM_only | |
| KCNMB4 | SNN | 0.415 | bioplex3_WMM WMM_only | |
| GRAMD1C | KCNMB4 | 0.35 | bioplex_WMM bioplex3_WMM WMM_only | |
| KCNMB4 | GRAMD1B | 0.333 | bioplex_WMM bioplex3_WMM WMM_only | |
| EXD2 | GRAMD2A | 0.261 | bioplex3_WMM WMM_only | |
| GRAMD2B | KCNMB4 | 0.214 | bioplex3_WMM WMM_only | |
| GRAMD1C | SNN | 0.113 | bioplex3_WMM WMM_only | |
| SNN | GRAMD1B | 0.095 | bioplex3_WMM WMM_only | |
| GRAMD2A | TMX1 | 0.066 | bioplex3_WMM WMM_only | |
| EXD2 | TMX1 | 0.04 | 0.252 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes