hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12718.1
Complex Portal: CPX-18198
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TLCD2 | TLC domain-containing protein 2 | 4 | UniProt NCBI |
| ATP8A1 | Phospholipid-transporting ATPase IA (EC 7.6.2.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1) | 5 | UniProt NCBI |
| TEX2 | Testis-expressed protein 2 (Transmembrane protein 96) | 4 | UniProt NCBI |
| SLC6A20 | Sodium- and chloride-dependent transporter XTRP3 (Sodium/imino-acid transporter 1) (Solute carrier family 6 member 20) (Transporter rB21A homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5029 | 0.049746753544 | 0.25 | SLC6A20 | Amino acid transport defects IEMs |
| REAC:R-HSA-5619101 | 0.0499436884912 | 0.25 | SLC6A20 | Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) |
| REAC:R-HSA-5660686 | 0.0499436884912 | 0.25 | SLC6A20 | Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ATP8A1 | SLC6A20 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SLC6A20 | TLCD2 | 0.964 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TEX2 | SLC6A20 | 0.946 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ATP8A1 | TLCD2 | 0.113 | bioplex3_WMM WMM_only | ||
| TEX2 | TLCD2 | 0.099 | bioplex3_WMM youn_WMM WMM_only | ||
| TEX2 | ATP8A1 | 0.076 | 0.102 | bioplex3_WMM WMM_only |
Related Complexes