hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_12719.1

Complex Portal: CPX-21155

Confidence: Medium

Show entries

Search:

Genename	Protein Name	Uniprot Annotation Score	Links
CHMP1B	Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2)	5	UniProt NCBI
CPXCR1	CPX chromosomal region candidate gene 1 protein (Cancer/testis antigen 77) (CT77)	2	UniProt NCBI
FLCN	Folliculin (BHD skin lesion fibrofolliculoma protein) (Birt-Hogg-Dube syndrome protein)	5	UniProt NCBI
FNIP1	Folliculin-interacting protein 1	5	UniProt NCBI
FNIP2	Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein)	5	UniProt NCBI
VTA1	Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1)	5	UniProt NCBI
ZFYVE19	Abscission/NoCut checkpoint regulator (ANCHR) (MLL partner containing FYVE domain) (Zinc finger FYVE domain-containing protein 19)	5	UniProt NCBI

Showing 1 to 7 of 7 entries

Show entries

Search:

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:7430	2.05265451394e-05	0.285714285714	FNIP2 FLCN	FLCN-FNIP2 complex
REAC:R-HSA-9639288	0.00030234111687	0.428571428571	FNIP2 FNIP1 FLCN	Amino acids regulate mTORC1
KEGG:04150	0.00180438218152	0.428571428571	FNIP2 FNIP1 FLCN	mTOR signaling pathway
WP:WP5381	0.00265193272199	0.428571428571	FNIP2 FNIP1 FLCN	Smith Magenis and Potocki Lupski syndrome copy number variation
REAC:R-HSA-9711097	0.00739955871017	0.428571428571	FNIP2 FNIP1 FLCN	Cellular response to starvation
GO:1905672	0.0294899169624	0.285714285714	FLCN FNIP1	negative regulation of lysosome organization

Showing 1 to 6 of 6 entries

Show entries

Search:

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
FNIP1	FNIP2	0.997		mutually_exclusive (Q8NFG4)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
VTA1	CHMP1B	0.994	0.052		hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
FNIP1	VTA1	0.992	0.088		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
FNIP2	VTA1	0.991			bioplex3_WMM bioplex3_HCT116 WMM_only
VTA1	FLCN	0.987	0.196		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
CPXCR1	VTA1	0.978			bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
VTA1	ZFYVE19	0.947	0.108		bioplex3_HEK293 bioplex3_WMM bioplex_WMM WMM_only
ZFYVE19	CHMP1B	0.881	0.038		bioplex3_HEK293 bioplex3_WMM WMM_only
FNIP2	FLCN	0.789		structurally_consistent (dimer)	bioplex3_WMM WMM_only
FNIP1	FLCN	0.72	0.16	structurally_consistent (dimer)	bioplex3_WMM WMM_only

Showing 1 to 10 of 13 entries

Related Complexes

Genename	Complexes
FNIP1	huMAP3_00964.1 huMAP3_03428.1 huMAP3_11896.1 huMAP3_12719.1 huMAP3_13009.1 huMAP3_15175.1
FNIP2	huMAP3_00964.1 huMAP3_03428.1 huMAP3_11896.1 huMAP3_12719.1 huMAP3_13009.1 huMAP3_15175.1
FLCN	huMAP3_09936.1 huMAP3_11302.1 huMAP3_12719.1 huMAP3_15175.1 huMAP3_15308.1
CPXCR1	huMAP3_00964.1 huMAP3_02353.1 huMAP3_03428.1 huMAP3_10064.1 huMAP3_11896.1 huMAP3_12646.1 huMAP3_12719.1 huMAP3_12735.1 huMAP3_14673.1 huMAP3_14919.1 huMAP3_15175.1
ZFYVE19	huMAP3_02745.1 huMAP3_05231.1 huMAP3_05825.1 huMAP3_05883.1 huMAP3_07639.1 huMAP3_10498.1 huMAP3_10811.1 huMAP3_11896.1 huMAP3_12719.1 huMAP3_14919.1 huMAP3_15175.1
CHMP1B	huMAP3_06564.1 huMAP3_08679.1 huMAP3_10053.1 huMAP3_11896.1 huMAP3_12719.1 huMAP3_13805.1 huMAP3_15175.1
VTA1	huMAP3_00964.1 huMAP3_03428.1 huMAP3_11896.1 huMAP3_12719.1 huMAP3_14919.1 huMAP3_15175.1