hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12732.1
Complex Portal: CPX-20601
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DPY19L3 | Protein C-mannosyl-transferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3) | 5 | UniProt NCBI |
| CFP | Properdin (Complement factor P) | 5 | UniProt NCBI |
| C8B | Complement component C8 beta chain (Complement component 8 subunit beta) | 5 | UniProt NCBI |
| RSPO3 | R-spondin-3 (Protein with TSP type-1 repeat) (hPWTSR) (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP545 | 0.000346844620397 | 0.5 | CFP C8B | Complement activation |
| REAC:R-HSA-977606 | 0.00837722051003 | 0.5 | CFP C8B | Regulation of Complement cascade |
| WP:WP5090 | 0.00992155513194 | 0.5 | CFP C8B | Complement system in neuronal development and plasticity |
| REAC:R-HSA-166658 | 0.0115164156767 | 0.5 | CFP C8B | Complement cascade |
| HP:0005339 | 0.034474601612 | 0.5 | CFP C8B | Abnormality of complement system |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DPY19L3 | C8B | 0.982 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| DPY19L3 | RSPO3 | 0.959 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CFP | DPY19L3 | 0.865 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes