hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12740.1
Complex Portal: CPX-14229
Confidence: Medium  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARX | Homeobox protein ARX (Aristaless-related homeobox) | 5 | UniProt   NCBI |
| SLAIN1 | SLAIN motif-containing protein 1 | 5 | UniProt   NCBI |
| TACC2 | Transforming acidic coiled-coil-containing protein 2 (Anti-Zuai-1) (AZU-1) | 5 | UniProt   NCBI |
| CKAP5 | Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG) | 5 | UniProt   NCBI |
| TUSC1 | Tumor suppressor candidate gene 1 protein (TSG-9) (TSG9) | 2 | UniProt   NCBI |
| TACC3 | Transforming acidic coiled-coil-containing protein 3 (ERIC-1) | 5 | UniProt   NCBI |
| SLAIN2 | SLAIN motif-containing protein 2 | 5 | UniProt   NCBI |
| TACC1 | Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1) | 5 | UniProt   NCBI |
| Q58EY0 | None | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   CORUM:631 | 8.20609246787e-05 | 0.222222222222 | CKAP5 TACC1 | Tacc1-chTOG-AuroraA complex |
|   CORUM:5373 | 8.20609246787e-05 | 0.222222222222 | TACC2 TACC3 | Chromatin remodeling complex (TACC2, TACC3, PCAF) |
|   GO:0000226 | 0.00550771776764 | 0.666666666667 | TACC2 SLAIN1 CKAP5 TACC1 TACC3 SLAIN2 | microtubule cytoskeleton organization |
|   WP:WP5365 | 0.0107100822997 | 0.222222222222 | CKAP5 TACC3 | 4p16 3 copy number variation |
|   GO:0035371 | 0.0162365457737 | 0.333333333333 | CKAP5 SLAIN1 SLAIN2 | microtubule plus-end |
|   GO:0031116 | 0.020844368733 | 0.333333333333 | CKAP5 SLAIN1 SLAIN2 | positive regulation of microtubule polymerization |
|   GO:0031112 | 0.0262477173145 | 0.333333333333 | CKAP5 SLAIN1 SLAIN2 | positive regulation of microtubule polymerization or depolymerization |
|   GO:0070507 | 0.03637848856 | 0.444444444444 | CKAP5 SLAIN2 SLAIN1 TACC3 | regulation of microtubule cytoskeleton organization |
|   GO:0007017 | 0.0416877457662 | 0.666666666667 | TACC2 SLAIN1 CKAP5 TACC1 TACC3 SLAIN2 | microtubule-based process |
|   GO:1990752 | 0.0478559415828 | 0.333333333333 | CKAP5 SLAIN1 SLAIN2 | microtubule end |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  CKAP5 |  SLAIN2 | 1.0 | 0.126           |          | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()     bioplex3_HCT116     gupta_WMM     fraction     |
|  CKAP5 |  TACC3 | 0.997 | 0.174           |          | hein_WMM     bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()     bioplex3_HCT116     gupta_WMM     fraction     |
|  TACC2 |  TACC1 | 0.997 |            |          | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()     gupta_WMM     |
|  CKAP5 |  SLAIN1 | 0.997 | 0.172           |          | hein_WMM     bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()     gupta_WMM     |
|  TACC3 |  SLAIN2 | 0.974 | 0.074           |          | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()     gupta_WMM     fraction     |
|  SLAIN1 |  TACC3 | 0.954 | 0.1           |          | bioplex3_HEK293     bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only     |
|  CKAP5 |  TACC2 | 0.947 |            |          | hein_WMM     bioplex3_WMM     youn_WMM     hein ()     |
|  SLAIN2 |  TACC2 | 0.925 |            |          | hein_WMM     youn_WMM     hein ()     |
|  TACC3 |  ARX | 0.902 |            |          | hein_WMM     hein ()     |
|  CKAP5 |  TACC1 | 0.882 | 0.1           |          | hein_WMM     bioplex3_HEK293     bioplex3_WMM     youn_WMM     hein ()     gupta_WMM     |
|  SLAIN1 |  TACC1 | 0.849 | 0.03           |          | hein_WMM     bioplex3_WMM     youn_WMM     hein ()     gupta_WMM     |
|  TACC3 |  TUSC1 | 0.832 | 0.062           |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
|  TACC3 |  TACC2 | 0.826 |            |          | hein_WMM     bioplex3_WMM     youn_WMM     WMM_only     |
|  SLAIN2 |  TACC1 | 0.574 | 0.042           |          | hein_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only     |
|  SLAIN1 |  TACC2 | 0.371 |            |          | hein_WMM     youn_WMM     hein ()     |
|  CKAP5 |  TUSC1 | 0.102 | 0.144           |          | bioplex3_WMM     WMM_only     |
|  SLAIN2 |  TUSC1 | 0.095 | 0.08           |          | bioplex3_WMM     WMM_only     |
|  TACC3 |  TACC1 | 0.082 | 0.178           |          | hein_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only     |
|  SLAIN1 |  TUSC1 | 0.076 | 0.048           |          | bioplex3_WMM     WMM_only     |
|  SLAIN1 |  SLAIN2 | 0.057 | 0.02           |          | bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only     |
Related Complexes