hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12766.1
Complex Portal: CPX-21402
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAD2L1BP | MAD2L1-binding protein (Caught by MAD2 protein) (p31(comet)) | 5 | UniProt NCBI |
| EPM2AIP1 | EPM2A-interacting protein 1 (Laforin-interacting protein) | 5 | UniProt NCBI |
| PRR12 | Proline-rich protein 12 | 4 | UniProt NCBI |
| MAD1L1 | Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181) | 5 | UniProt NCBI |
| KIF20A | Kinesin-like protein KIF20A (GG10_2) (Mitotic kinesin-like protein 2) (MKlp2) (Rab6-interacting kinesin-like protein) (Rabkinesin-6) | 5 | UniProt NCBI |
| PYROXD1 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-) | 5 | UniProt NCBI |
| POLA1 | DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180) | 5 | UniProt NCBI |
| CDCA7L | Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2) | 5 | UniProt NCBI |
| C15orf39 | Uncharacterized protein C15orf39 | 3 | UniProt NCBI |
| SLC26A4 | Pendrin (Sodium-independent chloride/iodide transporter) (Solute carrier family 26 member 4) | 5 | UniProt NCBI |
| TPR | Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0100786 | 0.0226469783291 | 0.2 | SLC26A4 PRR12 | Hypersomnia |
| CORUM:1813 | 0.0499436884912 | 0.1 | MAD1L1 | MAD1L1 homodimer complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MAD1L1 | MAD2L1BP | 1.0 | 0.372 |
mutually_exclusive (Q13257)
|
hein_WMM bioplex3_HEK293 bioplex3_WMM hein () bioplex3_HCT116 |
| MAD2L1BP | PYROXD1 | 0.997 | 0.146 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KIF20A | MAD2L1BP | 0.996 | 0.154 |
mutually_exclusive (Q13257)
|
hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| MAD2L1BP | EPM2AIP1 | 0.985 | 0.024 |
mutually_exclusive (Q13257)
|
hein_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| MAD2L1BP | C15orf39 | 0.979 | 0.176 | hein_WMM bioplex3_HEK293 bioplex3_WMM WMM_only | |
| KIF20A | MAD1L1 | 0.963 | 0.331102843291 |
mutually_exclusive (Q13257)
|
hein_WMM bioplex3_WMM WMM_only |
| TPR | MAD2L1BP | 0.956 | 0.202 | hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MAD1L1 | C15orf39 | 0.937 | 0.078 | hein_WMM bioplex3_WMM WMM_only | |
| MAD2L1BP | SLC26A4 | 0.93 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MAD2L1BP | POLA1 | 0.93 | 0.138 | hein_WMM bioplex3_WMM WMM_only | |
| POLA1 | C15orf39 | 0.928 | 0.09 | hein_WMM bioplex3_WMM WMM_only | |
| KIF20A | C15orf39 | 0.908 | 0.328 | hein_WMM bioplex3_WMM WMM_only | |
| EPM2AIP1 | PYROXD1 | 0.902 | 0.03 | bioplex3_WMM WMM_only | |
| MAD1L1 | TPR | 0.901 | 0.398 | hein_WMM bioplex_WMM Guru bioplex3_WMM fraction | |
| MAD1L1 | PYROXD1 | 0.892 | 0.126 | bioplex3_WMM WMM_only | |
| MAD1L1 | EPM2AIP1 | 0.889 | 0.03 |
mutually_exclusive (Q13257)
|
hein_WMM bioplex3_WMM WMM_only |
| PRR12 | C15orf39 | 0.882 | 0.166 | hein_WMM bioplex3_WMM WMM_only | |
| PRR12 | POLA1 | 0.879 | 0.048 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| EPM2AIP1 | C15orf39 | 0.876 | 0.056 | hein_WMM bioplex3_WMM WMM_only | |
| KIF20A | EPM2AIP1 | 0.874 | 0.0986666666667 |
mutually_exclusive (Q13257)
|
hein_WMM bioplex3_WMM WMM_only |
| PRR12 | KIF20A | 0.863 | 0.12 | hein_WMM bioplex3_WMM WMM_only | |
| TPR | EPM2AIP1 | 0.862 | 0.064 | hein_WMM bioplex3_WMM WMM_only | |
| MAD1L1 | POLA1 | 0.852 | 0.06 | hein_WMM bioplex3_WMM fraction | |
| MAD2L1BP | CDCA7L | 0.849 | 0.094 | hein_WMM hein () | |
| PRR12 | MAD2L1BP | 0.844 | 0.284 | hein_WMM bioplex3_WMM WMM_only | |
| PRR12 | MAD1L1 | 0.844 | 0.126 | hein_WMM bioplex3_WMM WMM_only | |
| EPM2AIP1 | POLA1 | 0.827 | 0.02 | hein_WMM bioplex3_WMM WMM_only | |
| PRR12 | EPM2AIP1 | 0.823 | 0.058 | hein_WMM bioplex3_WMM WMM_only | |
| KIF20A | POLA1 | 0.819 | 0.28 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| MAD1L1 | CDCA7L | 0.781 | 0.122 | hein_WMM WMM_only | |
| KIF20A | PYROXD1 | 0.768 | 0.084 | bioplex3_WMM WMM_only | |
| TPR | C15orf39 | 0.639 | 0.144 | hein_WMM bioplex3_WMM WMM_only | |
| PRR12 | TPR | 0.575 | 0.14 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| KIF20A | TPR | 0.512 | 0.832 | hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| TPR | PYROXD1 | 0.293 | 0.15 | bioplex3_WMM WMM_only | |
| PRR12 | CDCA7L | 0.232 | 0.094 | hein_WMM WMM_only | |
| POLA1 | CDCA7L | 0.232 | 0.106 | hein_WMM WMM_only | |
| C15orf39 | CDCA7L | 0.232 | 0.174 | hein_WMM WMM_only | |
| EPM2AIP1 | CDCA7L | 0.192 | 0.038 | hein_WMM WMM_only | |
| TPR | POLA1 | 0.063 | 0.096 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| TPR | CDCA7L | 0.063 | 0.164 | hein_WMM WMM_only | |
| KIF20A | CDCA7L | 0.063 | 0.182 | hein_WMM WMM_only | |
| PYROXD1 | C15orf39 | 0.043 | 0.18 | bioplex3_WMM WMM_only | |
| POLA1 | SLC26A4 | 0.012 | gupta_WMM WMM_only | ||
| TPR | SLC26A4 | 0.003 | bioplex3_HEK293 youn_WMM gupta_WMM WMM_only |
Related Complexes