hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12788.1
Complex Portal: CPX-24024
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MFAP5 | Microfibrillar-associated protein 5 (MFAP-5) (MP25) (Microfibril-associated glycoprotein 2) (MAGP-2) | 5 | UniProt NCBI |
| PRSS12 | Neurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12) | 5 | UniProt NCBI |
| SEMA3G | Semaphorin-3G (Semaphorin sem2) | 4 | UniProt NCBI |
| ACHE | Acetylcholinesterase (AChE) (EC 3.1.1.7) | 5 | UniProt NCBI |
| INS | Insulin [Cleaved into: Insulin B chain; Insulin A chain] | 5 | UniProt NCBI |
| B4GALNT4 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-422085 | 0.00200991204249 | 0.333333333333 | ACHE INS | Synthesis, secretion, and deacylation of Ghrelin |
| WP:WP661 | 0.0294502955092 | 0.166666666667 | INS | Glucose homeostasis |
| HP:0011104 | 0.0406481036194 | 0.333333333333 | MFAP5 INS | Abnormality of blood volume homeostasis |
| HP:0011106 | 0.0406481036194 | 0.333333333333 | MFAP5 INS | Hypovolemia |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| INS | PRSS12 | 0.977 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| INS | B4GALNT4 | 0.931 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SEMA3G | PRSS12 | 0.904 | bioplex3_WMM WMM_only | ||
| ACHE | PRSS12 | 0.904 | bioplex3_WMM WMM_only | ||
| PRSS12 | MFAP5 | 0.85 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| PRSS12 | B4GALNT4 | 0.076 | bioplex3_WMM WMM_only |
Related Complexes