hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_12795.1

Complex Portal: CPX-25593

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
CRELD1	Protein disulfide isomerase CRELD1 (EC 5.3.4.1) (Cysteine-rich with EGF-like domain protein 1)	5	UniProt NCBI
ORMDL2	ORM1-like protein 2 (Adoplin-2)	5	UniProt NCBI
ORMDL3	ORM1-like protein 3	5	UniProt NCBI
SCN9A	Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7)	5	UniProt NCBI
TMEM14C	Transmembrane protein 14C	5	UniProt NCBI

Showing 1 to 5 of 5 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-1660661	0.00849065158197	0.4	ORMDL3 ORMDL2	Sphingolipid de novo biosynthesis
GO:0035339	0.0280843539964	0.4	ORMDL3 ORMDL2	SPOTS complex
GO:0090156	0.0280843539964	0.4	ORMDL3 ORMDL2	intracellular sphingolipid homeostasis
REAC:R-HSA-428157	0.0395622673154	0.4	ORMDL3 ORMDL2	Sphingolipid metabolism
GO:1900060	0.0468008499735	0.4	ORMDL3 ORMDL2	negative regulation of ceramide biosynthetic process

Showing 1 to 5 of 5 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ORMDL2	ORMDL3	0.988	0.262		bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only
CRELD1	SCN9A	0.955			bioplex3_HEK293 bioplex3_WMM WMM_only
ORMDL2	CRELD1	0.918	0.074		bioplex3_HEK293 bioplex3_WMM WMM_only
CRELD1	TMEM14C	0.894	0.068		bioplex3_HEK293 bioplex3_WMM WMM_only
CRELD1	ORMDL3	0.865	0.136		bioplex3_HEK293 bioplex3_WMM WMM_only
SCN9A	TMEM14C	0.415			bioplex3_WMM WMM_only
SCN9A	ORMDL3	0.21			bioplex3_WMM WMM_only
ORMDL2	SCN9A	0.113			bioplex3_WMM WMM_only
ORMDL3	TMEM14C	0.078	0.056		bioplex3_WMM WMM_only
ORMDL2	TMEM14C	0.076	0.12		bioplex3_WMM WMM_only

Showing 1 to 10 of 10 entries

Related Complexes

Genename	Complexes
CRELD1	huMAP3_02543.1 huMAP3_05034.1 huMAP3_07728.1 huMAP3_07929.1 huMAP3_08938.1 huMAP3_12356.1 huMAP3_12795.1 huMAP3_12821.1 huMAP3_15312.1
SCN9A	huMAP3_02543.1 huMAP3_05034.1 huMAP3_07929.1 huMAP3_12356.1 huMAP3_12795.1 huMAP3_12821.1 huMAP3_15312.1
ORMDL3	huMAP3_02581.1 huMAP3_08192.1 huMAP3_08330.1 huMAP3_09129.1 huMAP3_09260.1 huMAP3_09967.1 huMAP3_10343.1 huMAP3_11807.1 huMAP3_12795.1 huMAP3_15312.1
ORMDL2	huMAP3_00816.1 huMAP3_02581.1 huMAP3_06154.1 huMAP3_08330.1 huMAP3_09129.1 huMAP3_09260.1 huMAP3_09967.1 huMAP3_10343.1 huMAP3_12356.1 huMAP3_12795.1 huMAP3_12903.1 huMAP3_15199.1 huMAP3_15312.1
TMEM14C	huMAP3_12356.1 huMAP3_12795.1 huMAP3_12821.1 huMAP3_15312.1