hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12814.1
Complex Portal: CPX-14957
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MPPE1 | Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5) | 5 | UniProt NCBI |
| SFTPC | Pulmonary surfactant-associated protein C (SP-C) (Pulmonary surfactant-associated proteolipid SPL(Val)) (SP5) | 5 | UniProt NCBI |
| ERVMER34-1 | Endogenous retroviral envelope protein HEMO (Endogenous retrovirus group MER34 member 1 Env polyprotein) (HERV-MER_4q12 provirus ancestral Env polyprotein) (Human endogenous MER34 (medium-reiteration-frequency-family-34) open reading frame) (Human endogenous MER34 ORF) (HEMO) [Cleaved into: Endogenous retroviral envelope protein HEMO, secreted form (Endogenous retroviral envelope protein HEMO, 48 kDa form)] | 5 | UniProt NCBI |
| F10 | Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain] | 5 | UniProt NCBI |
| TMEM106A | Transmembrane protein 106A | 5 | UniProt NCBI |
| LRRC3 | Leucine-rich repeat-containing protein 3 | 3 | UniProt NCBI |
| BRICD5 | BRICHOS domain-containing protein 5 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3162 | 0.0499436884912 | 0.166666666667 | F10 | TF-FVIIa-FXa-TFPI complex |
| CORUM:6276 | 0.0499436884912 | 0.166666666667 | F10 | Factor-Xa-TFPI-factor-VIIa-tissue factor complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LRRC3 | TMEM106A | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| F10 | TMEM106A | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ERVMER34-1 | TMEM106A | 0.994 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ERVMER34-1 | SFTPC | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MPPE1 | LRRC3 | 0.989 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SFTPC | F10 | 0.987 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ERVMER34-1 | BRICD5 | 0.982 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ERVMER34-1 | F10 | 0.355 | bioplex3_WMM WMM_only | ||
| ERVMER34-1 | LRRC3 | 0.335 | bioplex3_WMM WMM_only | ||
| F10 | LRRC3 | 0.323 | bioplex3_WMM WMM_only |
Related Complexes