hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12834.1
Complex Portal: CPX-25479
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NHLRC1 | E3 ubiquitin-protein ligase NHLRC1 (EC 2.3.2.27) (Malin) (NHL repeat-containing protein 1) (RING-type E3 ubiquitin transferase NHLRC1) | 5 | UniProt NCBI |
| SATB1 | DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1) | 5 | UniProt NCBI |
| RNF212 | Probable E3 SUMO-protein ligase RNF212 (EC 2.3.2.-) (Probable E3 SUMO-protein transferase RNF212) (RING finger protein 212) | 5 | UniProt NCBI |
| SATB2 | DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2) | 5 | UniProt NCBI |
| TRIM47 | E3 ubiquitin-protein ligase TRIM47 (EC 2.3.2.27) (Gene overexpressed in astrocytoma protein) (RING finger protein 100) (Tripartite motif-containing protein 47) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0002121 | 0.00744020362032 | 0.6 | SATB1 NHLRC1 SATB2 | Generalized non-motor (absence) seizure |
| HP:0033259 | 0.0105962255115 | 0.6 | SATB1 NHLRC1 SATB2 | Non-motor seizure |
| HP:0011146 | 0.0198915186532 | 0.6 | SATB1 NHLRC1 SATB2 | Dialeptic seizure |
| REAC:R-HSA-4551638 | 0.0323221445549 | 0.4 | SATB1 SATB2 | SUMOylation of chromatin organization proteins |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SATB1 | SATB2 | 0.998 | 0.208 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| SATB1 | TRIM47 | 0.997 | 0.036 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SATB2 | TRIM47 | 0.995 | 0.036 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NHLRC1 | TRIM47 | 0.994 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SATB2 | RNF212 | 0.933 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes