hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12835.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BIRC5 | Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin) | 5 | UniProt NCBI |
| LILRA5 | Leukocyte immunoglobulin-like receptor subfamily A member 5 (CD85 antigen-like family member F) (Immunoglobulin-like transcript 11) (ILT-11) (Leukocyte immunoglobulin-like receptor 9) (LIR-9) (CD antigen CD85f) | 5 | UniProt NCBI |
| CDCA8 | Borealin (Cell division cycle-associated protein 8) (Dasra-B) (hDasra-B) (Pluripotent embryonic stem cell-related gene 3 protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2582 | 1.02521027753e-05 | 0.666666666667 | BIRC5 CDCA8 | Chromosomal passenger complex CPC (CDCA8, AURKB, BIRC5) |
| CORUM:1120 | 1.02521027753e-05 | 0.666666666667 | BIRC5 CDCA8 | Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5) |
| CORUM:1118 | 2.05032700758e-05 | 0.666666666667 | BIRC5 CDCA8 | Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5, AURKB) |
| CORUM:1119 | 2.05032700758e-05 | 0.666666666667 | BIRC5 CDCA8 | Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5, AURKB) |
| REAC:R-HSA-4615885 | 0.00585997836812 | 0.666666666667 | BIRC5 CDCA8 | SUMOylation of DNA replication proteins |
| GO:0032133 | 0.0210651876021 | 0.666666666667 | BIRC5 CDCA8 | chromosome passenger complex |
| CORUM:2580 | 0.0249718442456 | 0.333333333333 | BIRC5 | Survivin homodimer complex |
| REAC:R-HSA-141444 | 0.0284248695791 | 0.666666666667 | BIRC5 CDCA8 | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| REAC:R-HSA-141424 | 0.0284248695791 | 0.666666666667 | BIRC5 CDCA8 | Amplification of signal from the kinetochores |
| GO:1903490 | 0.0294899169624 | 0.666666666667 | BIRC5 CDCA8 | positive regulation of mitotic cytokinesis |
| REAC:R-HSA-69618 | 0.0392065258044 | 0.666666666667 | BIRC5 CDCA8 | Mitotic Spindle Checkpoint |
| GO:1902412 | 0.0393180950424 | 0.666666666667 | BIRC5 CDCA8 | regulation of mitotic cytokinesis |
| GO:1902423 | 0.0393180950424 | 0.666666666667 | BIRC5 CDCA8 | regulation of attachment of mitotic spindle microtubules to kinetochore |
| GO:1902425 | 0.0393180950424 | 0.666666666667 | BIRC5 CDCA8 | positive regulation of attachment of mitotic spindle microtubules to kinetochore |
| REAC:R-HSA-9648025 | 0.0429286997388 | 0.666666666667 | BIRC5 CDCA8 | EML4 and NUDC in mitotic spindle formation |
| REAC:R-HSA-2500257 | 0.049233254294 | 0.666666666667 | BIRC5 CDCA8 | Resolution of Sister Chromatid Cohesion |
| CORUM:2581 | 0.0499402709677 | 0.333333333333 | BIRC5 | RasGAP-AURKA-survivin complex |
| CORUM:1117 | 0.0499402709677 | 0.333333333333 | BIRC5 | CRM1-Survivin mitotic complex |
| CORUM:6756 | 0.0499402709677 | 0.333333333333 | BIRC5 | RasGAP-AURKB-survivin complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| BIRC5 | CDCA8 | 0.999 | 0.59 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CDCA8 | LILRA5 | 0.939 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| BIRC5 | LILRA5 | 0.478 | bioplex3_WMM WMM_only |
Related Complexes