hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_12835.1

Complex Portal: CPX-11004

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
BIRC5	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)	5	UniProt NCBI
LILRA5	Leukocyte immunoglobulin-like receptor subfamily A member 5 (CD85 antigen-like family member F) (Immunoglobulin-like transcript 11) (ILT-11) (Leukocyte immunoglobulin-like receptor 9) (LIR-9) (CD antigen CD85f)	5	UniProt NCBI
CDCA8	Borealin (Cell division cycle-associated protein 8) (Dasra-B) (hDasra-B) (Pluripotent embryonic stem cell-related gene 3 protein)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:2582	1.02521027753e-05	0.666666666667	BIRC5 CDCA8	Chromosomal passenger complex CPC (CDCA8, AURKB, BIRC5)
CORUM:1120	1.02521027753e-05	0.666666666667	BIRC5 CDCA8	Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5)
CORUM:1118	2.05032700758e-05	0.666666666667	BIRC5 CDCA8	Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5, AURKB)
CORUM:1119	2.05032700758e-05	0.666666666667	BIRC5 CDCA8	Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5, AURKB)
REAC:R-HSA-4615885	0.00585997836812	0.666666666667	BIRC5 CDCA8	SUMOylation of DNA replication proteins
GO:0032133	0.0210651876021	0.666666666667	BIRC5 CDCA8	chromosome passenger complex
CORUM:2580	0.0249718442456	0.333333333333	BIRC5	Survivin homodimer complex
REAC:R-HSA-141444	0.0284248695791	0.666666666667	BIRC5 CDCA8	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
REAC:R-HSA-141424	0.0284248695791	0.666666666667	BIRC5 CDCA8	Amplification of signal from the kinetochores
GO:1903490	0.0294899169624	0.666666666667	BIRC5 CDCA8	positive regulation of mitotic cytokinesis
REAC:R-HSA-69618	0.0392065258044	0.666666666667	BIRC5 CDCA8	Mitotic Spindle Checkpoint
GO:1902412	0.0393180950424	0.666666666667	BIRC5 CDCA8	regulation of mitotic cytokinesis
GO:1902423	0.0393180950424	0.666666666667	BIRC5 CDCA8	regulation of attachment of mitotic spindle microtubules to kinetochore
GO:1902425	0.0393180950424	0.666666666667	BIRC5 CDCA8	positive regulation of attachment of mitotic spindle microtubules to kinetochore
REAC:R-HSA-9648025	0.0429286997388	0.666666666667	BIRC5 CDCA8	EML4 and NUDC in mitotic spindle formation
REAC:R-HSA-2500257	0.049233254294	0.666666666667	BIRC5 CDCA8	Resolution of Sister Chromatid Cohesion
CORUM:2581	0.0499402709677	0.333333333333	BIRC5	RasGAP-AURKA-survivin complex
CORUM:1117	0.0499402709677	0.333333333333	BIRC5	CRM1-Survivin mitotic complex
CORUM:6756	0.0499402709677	0.333333333333	BIRC5	RasGAP-AURKB-survivin complex

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
BIRC5	CDCA8	0.999	0.59		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
CDCA8	LILRA5	0.939			bioplex3_WMM bioplex3_HCT116 WMM_only
BIRC5	LILRA5	0.478			bioplex3_WMM WMM_only

Related Complexes

Genename	Complexes
BIRC5	huMAP3_00111.1 huMAP3_00910.1 huMAP3_00946.1 huMAP3_01130.1 huMAP3_04346.1 huMAP3_08157.1 huMAP3_08415.1 huMAP3_11479.1 huMAP3_12277.1 huMAP3_12835.1 huMAP3_14108.1 huMAP3_14708.1
LILRA5	huMAP3_01568.1 huMAP3_10223.1 huMAP3_12277.1 huMAP3_12463.1 huMAP3_12835.1
CDCA8	huMAP3_00111.1 huMAP3_00946.1 huMAP3_04305.1 huMAP3_04346.1 huMAP3_07363.1 huMAP3_07686.1 huMAP3_09538.1 huMAP3_11479.1 huMAP3_12277.1 huMAP3_12835.1