hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12839.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
SIX4 | Homeobox protein SIX4 (Sine oculis homeobox homolog 4) | 5 | UniProt   NCBI |
RFC2 | Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) | 5 | UniProt   NCBI |
ATAD5 | ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein) | 5 | UniProt   NCBI |
RFC3 | Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38) | 5 | UniProt   NCBI |
RFC5 | Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) | 5 | UniProt   NCBI |
CHTF18 | Chromosome transmission fidelity protein 18 homolog (hCTF18) (CHL12) | 5 | UniProt   NCBI |
PDCD2 | Programmed cell death protein 2 (Zinc finger MYND domain-containing protein 7) (Zinc finger protein Rp-8) | 5 | UniProt   NCBI |
DSCC1 | Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog) | 5 | UniProt   NCBI |
UHRF2 | E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2) | 5 | UniProt   NCBI |
RFC4 | Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) | 5 | UniProt   NCBI |
CHTF8 | Chromosome transmission fidelity protein 8 homolog (hCTF8) | 4 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  CORUM:2804 | 7.76518645207e-22 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | CTF18-cohesion-RFC complex |
  CORUM:3070 | 6.21066076338e-21 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | CTF18-cohesion-RFC-POLH complex |
  GO:0003689 | 4.67662755482e-18 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | DNA clamp loader activity |
  GO:0031390 | 4.67662755482e-18 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | Ctf18 RFC-like complex |
  GO:1900262 | 2.10397814799e-17 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | regulation of DNA-directed DNA polymerase activity |
  GO:1900264 | 2.10397814799e-17 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | positive regulation of DNA-directed DNA polymerase activity |
  REAC:R-HSA-174411 | 1.98383310337e-15 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | Polymerase switching on the C-strand of the telomere |
  CORUM:2199 | 5.52460635237e-15 | 0.454545454545 | RFC2 RFC4 RFC5 CHTF18 RFC3 | CHTF18-RFC2-5 complex |
  CORUM:2202 | 5.52460635237e-15 | 0.454545454545 | RFC2 RFC4 RFC5 CHTF18 RFC3 | CHTF18-RFC2-5 complex |
  CORUM:2797 | 5.52460635237e-15 | 0.454545454545 | RFC2 RFC4 RFC5 CHTF18 RFC3 | PCNA-CHL12-RFC2-5 complex |
  REAC:R-HSA-174417 | 1.61930603028e-14 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | Telomere C-strand (Lagging Strand) Synthesis |
  GO:0017116 | 9.93623097321e-14 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | single-stranded DNA helicase activity |
  REAC:R-HSA-180786 | 3.47072449283e-13 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | Extension of Telomeres |
  GO:0090329 | 8.9247603052e-12 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | regulation of DNA-templated DNA replication |
  CORUM:2200 | 1.15314319164e-11 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | RFC2-5 subcomplex |
  CORUM:2201 | 1.15314319164e-11 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | PCNA-RFC2-5 complex |
  CORUM:613 | 1.15314319164e-11 | 0.363636363636 | RFC3 CHTF8 CHTF18 DSCC1 | CTF18-CTF8-DCC1-RFC3 complex |
  GO:0008094 | 1.46757259141e-11 | 0.727272727273 | CHTF8 ATAD5 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | ATP-dependent activity, acting on DNA |
  GO:0006275 | 2.47840922108e-11 | 0.727272727273 | CHTF8 ATAD5 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | regulation of DNA replication |
  REAC:R-HSA-157579 | 4.74253984172e-11 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | Telomere Maintenance |
  CORUM:277 | 5.76350611564e-11 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | RFC complex |
  CORUM:270 | 5.76350611564e-11 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | RAD17-RFC complex |
  CORUM:266 | 5.76350611564e-11 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | RAD17-RFC complex |
  CORUM:2810 | 5.76350611564e-11 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | RAD17-RFC complex |
  CORUM:2799 | 5.76350611564e-11 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | RFC complex |
  CORUM:279 | 5.76350611564e-11 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | RFC complex |
  GO:0003678 | 1.17296841983e-10 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | DNA helicase activity |
  CORUM:2203 | 1.72838910881e-10 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | BRD4-RFC complex |
  GO:2000573 | 1.9700268993e-10 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | positive regulation of DNA biosynthetic process |
  REAC:R-HSA-73886 | 2.63017512463e-10 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | Chromosome Maintenance |
  CORUM:1003 | 8.05963357471e-10 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | RC complex (Replication competent complex) |
  CORUM:274 | 8.05963357471e-10 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | 9-1-1-RAD17-RFC complex |
  CORUM:268 | 8.05963357471e-10 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | 9-1-1-RAD17-RFC complex |
  WP:WP2363 | 8.46847194038e-10 | 0.454545454545 | RFC3 CHTF8 RFC4 CHTF18 DSCC1 | Gastric cancer network 2 |
  GO:0140097 | 6.37918996025e-09 | 0.727272727273 | CHTF8 ATAD5 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | catalytic activity, acting on DNA |
  GO:2000278 | 7.35077323208e-09 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | regulation of DNA biosynthetic process |
  GO:0006260 | 1.52988925212e-08 | 0.727272727273 | CHTF8 ATAD5 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | DNA replication |
  GO:0004386 | 2.06552436833e-08 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | helicase activity |
  CORUM:278 | 2.10621603952e-08 | 0.272727272727 | RFC2 RFC5 RFC4 | RFC core complex |
  CORUM:2806 | 2.10621603952e-08 | 0.272727272727 | CHTF8 CHTF18 DSCC1 | CTF18-CTF8-DCC1 complex |
  CORUM:612 | 2.10621603952e-08 | 0.272727272727 | CHTF8 CHTF18 DSCC1 | CTF18-CTF8-DCC1 complex |
  GO:0051054 | 3.59928098431e-08 | 0.727272727273 | CHTF8 ATAD5 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | positive regulation of DNA metabolic process |
  GO:0005663 | 4.33992010508e-08 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | DNA replication factor C complex |
  REAC:R-HSA-69091 | 4.48631562508e-08 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Polymerase switching |
  REAC:R-HSA-69109 | 4.48631562508e-08 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Leading Strand Synthesis |
  KEGG:03430 | 7.78096363318e-08 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Mismatch repair |
  REAC:R-HSA-5656121 | 8.15068333788e-08 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Translesion synthesis by POLI |
  REAC:R-HSA-110312 | 8.15068333788e-08 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Translesion synthesis by REV1 |
  REAC:R-HSA-5655862 | 1.06544987436e-07 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Translesion synthesis by POLK |
  GO:0006261 | 1.06992282147e-07 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | DNA-templated DNA replication |
  GO:0071897 | 1.1827539665e-07 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | DNA biosynthetic process |
  WP:WP531 | 1.59355434742e-07 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | DNA mismatch repair |
  REAC:R-HSA-110320 | 1.73383066136e-07 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Translesion Synthesis by POLH |
  REAC:R-HSA-69186 | 2.16645715224e-07 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Lagging Strand Synthesis |
  REAC:R-HSA-5651801 | 2.67518538301e-07 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | PCNA-Dependent Long Patch Base Excision Repair |
  WP:WP5366 | 5.14535835656e-07 | 0.454545454545 | RFC2 RFC5 RFC4 ATAD5 RFC3 | NF1 copy number variation syndrome |
  KEGG:03030 | 5.15027537214e-07 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | DNA replication |
  REAC:R-HSA-5696397 | 5.64564812893e-07 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Gap-filling DNA repair synthesis and ligation in GG-NER |
  REAC:R-HSA-110373 | 5.64564812893e-07 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
  KEGG:03410 | 1.07612214936e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Base excision repair |
  REAC:R-HSA-110314 | 1.2207307241e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Recognition of DNA damage by PCNA-containing replication complex |
  REAC:R-HSA-5656169 | 1.40104195922e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Termination of translesion DNA synthesis |
  REAC:R-HSA-69190 | 1.60057643707e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | DNA strand elongation |
  WP:WP466 | 1.99966829504e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | DNA replication |
  REAC:R-HSA-9709570 | 2.06260783556e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Impaired BRCA2 binding to RAD51 |
  WP:WP4753 | 2.20391613469e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Nucleotide excision repair |
  REAC:R-HSA-5685938 | 2.32785713544e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | HDR through Single Strand Annealing (SSA) |
  REAC:R-HSA-73933 | 2.32785713544e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Resolution of Abasic Sites (AP sites) |
  GO:0140657 | 2.44278598737e-06 | 0.727272727273 | CHTF8 ATAD5 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | ATP-dependent activity |
  REAC:R-HSA-176187 | 2.61783426947e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Activation of ATR in response to replication stress |
  GO:0051052 | 3.08663606456e-06 | 0.727272727273 | CHTF8 ATAD5 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | regulation of DNA metabolic process |
  REAC:R-HSA-110313 | 3.2779414915e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template |
  REAC:R-HSA-5693616 | 3.65116149301e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Presynaptic phase of homologous DNA pairing and strand exchange |
  KEGG:03420 | 3.67833724774e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Nucleotide excision repair |
  REAC:R-HSA-9675136 | 4.05528898927e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Diseases of DNA Double-Strand Break Repair |
  REAC:R-HSA-9701190 | 4.05528898927e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Defective homologous recombination repair (HRR) due to BRCA2 loss of function |
  REAC:R-HSA-5696400 | 4.49197375051e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Dual Incision in GG-NER |
  REAC:R-HSA-5693579 | 4.96290732292e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Homologous DNA Pairing and Strand Exchange |
  REAC:R-HSA-73893 | 7.89342534617e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | DNA Damage Bypass |
  REAC:R-HSA-9675135 | 9.36923360894e-06 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Diseases of DNA repair |
  GO:0140640 | 1.21581805206e-05 | 0.727272727273 | CHTF8 ATAD5 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | catalytic activity, acting on a nucleic acid |
  GO:0051347 | 1.35882191211e-05 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | positive regulation of transferase activity |
  WP:WP5114 | 1.92149687159e-05 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Nucleotide excision repair in xeroderma pigmentosum |
  REAC:R-HSA-1640170 | 2.36211009449e-05 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | Cell Cycle |
  REAC:R-HSA-6782210 | 2.61992380384e-05 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Gap-filling DNA repair synthesis and ligation in TC-NER |
  REAC:R-HSA-6782135 | 2.79351170616e-05 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Dual incision in TC-NER |
  GO:0005694 | 3.107722397e-05 | 0.909090909091 | DSCC1 UHRF2 RFC4 CHTF18 RFC3 RFC5 CHTF8 RFC2 SIX4 ATAD5 | chromosome |
  REAC:R-HSA-5685942 | 3.16630294761e-05 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | HDR through Homologous Recombination (HRR) |
  CORUM:2805 | 3.41979277617e-05 | 0.181818181818 | CHTF8 DSCC1 | CTF8-DCC1 subcomplex |
  GO:0043085 | 4.72718628721e-05 | 0.727272727273 | CHTF8 RFC4 CHTF18 RFC3 DSCC1 RFC2 PDCD2 RFC5 | positive regulation of catalytic activity |
  REAC:R-HSA-73884 | 5.61480508088e-05 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Base Excision Repair |
  REAC:R-HSA-6781827 | 5.92018899877e-05 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
  REAC:R-HSA-5696399 | 8.02053265718e-05 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Global Genome Nucleotide Excision Repair (GG-NER) |
  REAC:R-HSA-69473 | 9.70027469308e-05 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | G2/M DNA damage checkpoint |
  REAC:R-HSA-6804756 | 0.000106322305899 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Regulation of TP53 Activity through Phosphorylation |
  REAC:R-HSA-5693607 | 0.000111224734674 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Processing of DNA double-strand break ends |
  WP:WP4946 | 0.000111932560618 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | DNA repair pathways full network |
  CORUM:6304 | 0.000205019103882 | 0.181818181818 | CHTF18 DSCC1 | DDX11-Ctf18-RFC complex |
  REAC:R-HSA-5696398 | 0.000231665446959 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Nucleotide Excision Repair |
  REAC:R-HSA-69239 | 0.000341815572044 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Synthesis of DNA |
  GO:0006259 | 0.000385785150293 | 0.727272727273 | CHTF8 ATAD5 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | DNA metabolic process |
  REAC:R-HSA-5693567 | 0.000390194778142 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
  REAC:R-HSA-5693538 | 0.000472084716533 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Homology Directed Repair |
  CORUM:435 | 0.000512126948792 | 0.181818181818 | RFC2 RFC4 | BASC (Ab 81) complex (BRCA1-associated genome surveillance complex) |
  GO:0051338 | 0.000556366035981 | 0.636363636364 | CHTF8 RFC4 RFC3 DSCC1 RFC2 CHTF18 RFC5 | regulation of transferase activity |
  REAC:R-HSA-5633007 | 0.000908434228529 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Regulation of TP53 Activity |
  CORUM:434 | 0.000955185435728 | 0.181818181818 | RFC2 RFC4 | BASC (Ab 80) complex (BRCA1-associated genome surveillance complex) |
  GO:0044093 | 0.000971417854021 | 0.727272727273 | CHTF8 RFC4 CHTF18 RFC3 DSCC1 RFC2 PDCD2 RFC5 | positive regulation of molecular function |
  REAC:R-HSA-5693532 | 0.00105974986669 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | DNA Double-Strand Break Repair |
  GO:0045935 | 0.00107023282951 | 0.818181818182 | DSCC1 CHTF8 RFC4 CHTF18 RFC3 RFC5 RFC2 SIX4 ATAD5 | positive regulation of nucleobase-containing compound metabolic process |
  REAC:R-HSA-69481 | 0.00108667895748 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | G2/M Checkpoints |
  REAC:R-HSA-69242 | 0.00108667895748 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | S Phase |
  GO:0051173 | 0.00141607801033 | 0.909090909091 | PDCD2 DSCC1 CHTF8 RFC4 CHTF18 RFC3 RFC5 RFC2 SIX4 ATAD5 | positive regulation of nitrogen compound metabolic process |
  REAC:R-HSA-69306 | 0.00155463625652 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | DNA Replication |
  GO:0050790 | 0.00205594011135 | 0.727272727273 | CHTF8 RFC4 CHTF18 RFC3 DSCC1 RFC2 PDCD2 RFC5 | regulation of catalytic activity |
  CORUM:433 | 0.00224781298839 | 0.181818181818 | RFC2 RFC4 | BASC complex (BRCA1-associated genome surveillance complex) |
  WP:WP2446 | 0.00327481493699 | 0.272727272727 | RFC3 RFC5 RFC4 | Retinoblastoma gene in cancer |
  WP:WP4932 | 0.00455328541335 | 0.272727272727 | RFC2 RFC5 CHTF18 | 7q11 23 copy number variation syndrome |
  GO:0010604 | 0.00480782478495 | 0.909090909091 | PDCD2 DSCC1 CHTF8 RFC4 CHTF18 RFC3 RFC5 RFC2 SIX4 ATAD5 | positive regulation of macromolecule metabolic process |
  GO:0005657 | 0.00574280977106 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | replication fork |
  REAC:R-HSA-69620 | 0.00999783931495 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Cell Cycle Checkpoints |
  GO:0009893 | 0.0115687276002 | 0.909090909091 | PDCD2 DSCC1 CHTF8 RFC4 CHTF18 RFC3 RFC5 RFC2 SIX4 ATAD5 | positive regulation of metabolic process |
  REAC:R-HSA-73894 | 0.014343574904 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | DNA Repair |
  REAC:R-HSA-3700989 | 0.0211277606193 | 0.363636363636 | RFC2 RFC4 RFC5 RFC3 | Transcriptional Regulation by TP53 |
  GO:0065009 | 0.0483725796336 | 0.727272727273 | CHTF8 RFC4 CHTF18 RFC3 DSCC1 RFC2 PDCD2 RFC5 | regulation of molecular function |
  CORUM:1131 | 0.049976851631 | 0.0909090909091 | RFC2 | RFC2-RIalpha complex |
  CORUM:1132 | 0.049976851631 | 0.0909090909091 | RFC4 | RFC2-RIalpha complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD |
---|---|---|---|
 RFC5 |  RFC4 | 1.0 | 0.946           |
 RFC2 |  RFC5 | 1.0 | 0.978           |
 RFC3 |  RFC5 | 1.0 | 0.898           |
 RFC3 |  RFC4 | 1.0 | 0.802           |
 DSCC1 |  CHTF8 | 1.0 | 0.360666666667           |
 CHTF18 |  RFC5 | 1.0 | 0.342           |
 DSCC1 |  RFC3 | 1.0 | 0.368           |
 CHTF18 |  DSCC1 | 1.0 | 0.328           |
 CHTF18 |  RFC4 | 0.999 | 0.272           |
 RFC2 |  RFC4 | 0.999 | 0.942           |
 DSCC1 |  RFC5 | 0.999 | 0.464           |
 RFC2 |  RFC3 | 0.999 | 0.948           |
 DSCC1 |  RFC2 | 0.999 | 0.388           |
 CHTF8 |  RFC5 | 0.999 | 0.322           |
 DSCC1 |  RFC4 | 0.999 | 0.48           |
 CHTF8 |  RFC4 | 0.999 | 0.38           |
 ATAD5 |  RFC5 | 0.998 | 0.206           |
 ATAD5 |  RFC4 | 0.996 | 0.258           |
 RFC2 |  ATAD5 | 0.986 | 0.29           |
 CHTF18 |  RFC2 | 0.982 | 0.316           |
 CHTF18 |  CHTF8 | 0.979 | 0.37           |
 CHTF18 |  RFC3 | 0.947 | 0.258           |
 RFC3 |  PDCD2 | 0.924 | 0.09           |
 CHTF8 |  RFC2 | 0.893 | 0.344           |
 CHTF8 |  RFC3 | 0.872 | 0.208           |
 DSCC1 |  SIX4 | 0.86 | 0.118           |
 RFC2 |  UHRF2 | 0.817 | 0.074           |
 RFC5 |  UHRF2 | 0.817 | 0.102           |
 RFC4 |  UHRF2 | 0.808 | 0.076           |
 CHTF18 |  UHRF2 | 0.781 | 0.088           |
 CHTF18 |  SIX4 | 0.725 | 0.078           |
 RFC2 |  PDCD2 | 0.649 | 0.132           |
 ATAD5 |  RFC3 | 0.643 | 0.216           |
 RFC4 |  SIX4 | 0.617 | 0.082           |
 UHRF2 |  SIX4 | 0.504 | 0.072           |
 RFC5 |  PDCD2 | 0.463 | 0.192           |
 RFC3 |  UHRF2 | 0.454 | 0.126           |
 CHTF18 |  ATAD5 | 0.426 | 0.132           |
 RFC3 |  SIX4 | 0.403 | 0.06           |
 RFC2 |  SIX4 | 0.398 | 0.076           |
 RFC5 |  SIX4 | 0.276 | 0.068           |
 DSCC1 |  ATAD5 | 0.263 | 0.162           |
 DSCC1 |  UHRF2 | 0.245 | 0.074           |
 CHTF8 |  ATAD5 | 0.202 | 0.098           |
 ATAD5 |  SIX4 | 0.114 | 0.174           |
 ATAD5 |  UHRF2 | 0.076 | 0.118           |
 ATAD5 |  PDCD2 | 0.073 | 0.16           |
 RFC4 |  PDCD2 | 0.066 | 0.16           |
 PDCD2 |  SIX4 | 0.06 | 0.104           |
 DSCC1 |  PDCD2 | 0.023 | 0.204           |
 CHTF18 |  PDCD2 | 0.008 | 0.08           |
Related Complexes