hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_12839.1

Complex Portal: CPX-13085

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
ATAD5	ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)	5	UniProt NCBI
CHTF18	Chromosome transmission fidelity protein 18 homolog (hCTF18) (CHL12)	5	UniProt NCBI
CHTF8	Chromosome transmission fidelity protein 8 homolog (hCTF8)	4	UniProt NCBI
DSCC1	Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog)	5	UniProt NCBI
PDCD2	Programmed cell death protein 2 (Zinc finger MYND domain-containing protein 7) (Zinc finger protein Rp-8)	5	UniProt NCBI
RFC2	Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40)	5	UniProt NCBI
RFC3	Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38)	5	UniProt NCBI
RFC4	Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37)	5	UniProt NCBI
RFC5	Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36)	5	UniProt NCBI
SIX4	Homeobox protein SIX4 (Sine oculis homeobox homolog 4)	5	UniProt NCBI

Showing 1 to 10 of 11 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:2804	7.76518645207e-22	0.636363636364	CHTF18 RFC4 RFC2 RFC3 CHTF8 DSCC1 RFC5	CTF18-cohesion-RFC complex
CORUM:3070	6.21066076338e-21	0.636363636364	CHTF18 RFC4 RFC2 RFC3 CHTF8 DSCC1 RFC5	CTF18-cohesion-RFC-POLH complex
GO:0003689	4.67662755482e-18	0.636363636364	CHTF18 RFC4 RFC2 RFC3 CHTF8 DSCC1 RFC5	DNA clamp loader activity
GO:0031390	4.67662755482e-18	0.636363636364	CHTF18 RFC4 RFC2 RFC3 CHTF8 DSCC1 RFC5	Ctf18 RFC-like complex
GO:1900262	2.10397814799e-17	0.636363636364	CHTF18 RFC4 RFC2 RFC3 CHTF8 DSCC1 RFC5	regulation of DNA-directed DNA polymerase activity
GO:1900264	2.10397814799e-17	0.636363636364	CHTF18 RFC4 RFC2 RFC3 CHTF8 DSCC1 RFC5	positive regulation of DNA-directed DNA polymerase activity
REAC:R-HSA-174411	1.98383310337e-15	0.636363636364	CHTF18 RFC4 RFC2 RFC3 CHTF8 DSCC1 RFC5	Polymerase switching on the C-strand of the telomere
CORUM:2199	5.52460635237e-15	0.454545454545	RFC2 RFC4 RFC3 CHTF18 RFC5	CHTF18-RFC2-5 complex
CORUM:2202	5.52460635237e-15	0.454545454545	RFC2 RFC4 RFC3 CHTF18 RFC5	CHTF18-RFC2-5 complex
CORUM:2797	5.52460635237e-15	0.454545454545	RFC2 RFC4 RFC3 CHTF18 RFC5	PCNA-CHL12-RFC2-5 complex

Showing 1 to 10 of 127 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
RFC5	RFC4	1.0	0.946
RFC2	RFC5	1.0	0.978
RFC3	RFC5	1.0	0.898
RFC3	RFC4	1.0	0.802
DSCC1	CHTF8	1.0	0.360666666667	structurally_consistent (dimer)
CHTF18	RFC5	1.0	0.342
DSCC1	RFC3	1.0	0.368	structurally_consistent (Q8WVB6)
CHTF18	DSCC1	1.0	0.328	structurally_consistent (dimer)
CHTF18	RFC4	0.999	0.272	structurally_consistent (dimer)
RFC2	RFC4	0.999	0.942

Showing 1 to 10 of 51 entries

Related Complexes

Genename	Complexes
SIX4	huMAP3_12092.1 huMAP3_12194.1 huMAP3_12839.1
RFC2	huMAP3_00703.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07313.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_09476.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_14232.1
ATAD5	huMAP3_00703.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08497.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_09476.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_13325.1 huMAP3_14232.1
RFC3	huMAP3_00703.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_07717.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_09525.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_14232.1
RFC5	huMAP3_00703.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08497.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_09476.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_13325.1 huMAP3_14232.1
CHTF18	huMAP3_00015.1 huMAP3_00703.1 huMAP3_02396.1 huMAP3_05600.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_10568.1 huMAP3_11446.1 huMAP3_11579.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_13325.1 huMAP3_14232.1
PDCD2	huMAP3_11211.1 huMAP3_11874.1 huMAP3_12462.1 huMAP3_12727.1 huMAP3_12839.1
DSCC1	huMAP3_00015.1 huMAP3_00703.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_13325.1 huMAP3_14232.1
UHRF2	huMAP3_05267.1 huMAP3_07212.1 huMAP3_07314.1 huMAP3_07820.1 huMAP3_11516.1 huMAP3_12385.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_14232.1
RFC4	huMAP3_00703.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08497.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_09476.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_14232.1
CHTF8	huMAP3_00015.1 huMAP3_00703.1 huMAP3_02396.1 huMAP3_02520.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_10568.1 huMAP3_11579.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_13325.1 huMAP3_14232.1