hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12852.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IL6R | Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD antigen CD126) [Cleaved into: Soluble interleukin-6 receptor subunit alpha (sIL6R)] | 5 | UniProt NCBI |
| ANO4 | Anoctamin-4 (Transmembrane protein 16D) | 5 | UniProt NCBI |
| ANO9 | Anoctamin-9 (Transmembrane protein 16J) (Tumor protein p53-inducible protein 5) (p53-induced gene 5 protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9733458 | 0.00024538606603 | 0.666666666667 | ANO9 ANO4 | Induction of Cell-Cell Fusion |
| REAC:R-HSA-9679506 | 0.00410096621855 | 1.0 | ANO9 IL6R ANO4 | SARS-CoV Infections |
| KEGG:04148 | 0.00578906402762 | 0.666666666667 | ANO9 ANO4 | Efferocytosis |
| REAC:R-HSA-9772573 | 0.0128584085686 | 0.666666666667 | ANO9 ANO4 | Late SARS-CoV-2 Infection Events |
| REAC:R-HSA-2672351 | 0.0141416283812 | 0.666666666667 | ANO9 ANO4 | Stimuli-sensing channels |
| REAC:R-HSA-9824446 | 0.0269033233908 | 1.0 | ANO9 IL6R ANO4 | Viral Infection Pathways |
| REAC:R-HSA-5663205 | 0.0499835710674 | 1.0 | ANO9 IL6R ANO4 | Infectious disease |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IL6R | ANO4 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ANO4 | ANO9 | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IL6R | ANO9 | 0.902 | bioplex3_WMM WMM_only |
Related Complexes