hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12855.1
Complex Portal: CPX-23095
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| VASP | Vasodilator-stimulated phosphoprotein (VASP) | 5 | UniProt NCBI |
| CASP7 | Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] | 5 | UniProt NCBI |
| ARX | Homeobox protein ARX (Aristaless-related homeobox) | 5 | UniProt NCBI |
| SLAIN1 | SLAIN motif-containing protein 1 | 5 | UniProt NCBI |
| TACC2 | Transforming acidic coiled-coil-containing protein 2 (Anti-Zuai-1) (AZU-1) | 5 | UniProt NCBI |
| CKAP5 | Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG) | 5 | UniProt NCBI |
| TUSC1 | Tumor suppressor candidate gene 1 protein (TSG-9) (TSG9) | 2 | UniProt NCBI |
| TACC3 | Transforming acidic coiled-coil-containing protein 3 (ERIC-1) | 5 | UniProt NCBI |
| SLAIN2 | SLAIN motif-containing protein 2 | 5 | UniProt NCBI |
| TACC1 | Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1) | 5 | UniProt NCBI |
| Q58EY0 | None | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:631 | 0.000102551658964 | 0.181818181818 | CKAP5 TACC1 | Tacc1-chTOG-AuroraA complex |
| CORUM:5373 | 0.000102551658964 | 0.181818181818 | TACC3 TACC2 | Chromatin remodeling complex (TACC2, TACC3, PCAF) |
| GO:0032273 | 0.0053914775929 | 0.363636363636 | SLAIN1 VASP SLAIN2 CKAP5 | positive regulation of protein polymerization |
| WP:WP5365 | 0.0186770164082 | 0.181818181818 | CKAP5 TACC3 | 4p16 3 copy number variation |
| GO:0000226 | 0.0285893467678 | 0.545454545455 | CKAP5 TACC1 SLAIN2 TACC2 SLAIN1 TACC3 | microtubule cytoskeleton organization |
| GO:0035371 | 0.0318245054916 | 0.272727272727 | SLAIN1 SLAIN2 CKAP5 | microtubule plus-end |
| GO:0031116 | 0.0408476954791 | 0.272727272727 | SLAIN1 SLAIN2 CKAP5 | positive regulation of microtubule polymerization |
| CORUM:6731 | 0.049976851631 | 0.0909090909091 | VASP | VASP-CXCR2 complex, CXCL8 stimulated |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CKAP5 | SLAIN2 | 1.0 | 0.126 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction | |
| CKAP5 | TACC3 | 0.997 | 0.174 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction | |
| TACC2 | TACC1 | 0.997 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM | ||
| CKAP5 | SLAIN1 | 0.997 | 0.172 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM | |
| TACC3 | VASP | 0.989 | 0.08 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () gupta_WMM | |
| TACC3 | SLAIN2 | 0.974 | 0.074 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM fraction | |
| SLAIN1 | TACC3 | 0.954 | 0.1 | bioplex3_HEK293 bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| SLAIN2 | VASP | 0.95 | 0.066 | hein_WMM bioplex3_WMM WMM_only | |
| CKAP5 | TACC2 | 0.947 | hein_WMM bioplex3_WMM youn_WMM hein () | ||
| SLAIN2 | TACC2 | 0.925 | hein_WMM youn_WMM hein () | ||
| TACC3 | ARX | 0.902 | hein_WMM hein () | ||
| CKAP5 | TACC1 | 0.882 | 0.1 | hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM hein () gupta_WMM | |
| SLAIN1 | TACC1 | 0.849 | 0.03 | hein_WMM bioplex3_WMM youn_WMM hein () gupta_WMM | |
| SLAIN1 | CASP7 | 0.837 | 0.042 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| TACC3 | TUSC1 | 0.832 | 0.062 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| TACC3 | TACC2 | 0.826 | hein_WMM bioplex3_WMM youn_WMM WMM_only | ||
| SLAIN2 | TACC1 | 0.574 | 0.042 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| CKAP5 | VASP | 0.494 | 0.082 | hein_WMM bioplex3_WMM gupta_WMM WMM_only | |
| SLAIN1 | TACC2 | 0.371 | hein_WMM youn_WMM hein () | ||
| CKAP5 | TUSC1 | 0.102 | 0.144 | bioplex3_WMM WMM_only | |
| SLAIN2 | TUSC1 | 0.095 | 0.08 | bioplex3_WMM WMM_only | |
| TACC3 | TACC1 | 0.082 | 0.178 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| VASP | TUSC1 | 0.078 | 0.094 | bioplex3_WMM WMM_only | |
| SLAIN1 | TUSC1 | 0.076 | 0.048 | bioplex3_WMM WMM_only | |
| SLAIN1 | SLAIN2 | 0.057 | 0.02 | bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| SLAIN1 | VASP | 0.029 | 0.054 | bioplex3_WMM gupta_WMM WMM_only | |
| VASP | TACC2 | 0.016 | bioplex3_WMM WMM_only | ||
| VASP | TACC1 | 0.005 | 0.1 | gupta_WMM WMM_only | |
| CKAP5 | CASP7 | 0.004 | 0.05 | gupta_WMM fraction |
Related Complexes