hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
ASCC2	Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100)	5	UniProt NCBI
ALKBH3	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (EC 1.14.11.33) (EC 1.14.11.54) (Alkylated DNA repair protein alkB homolog 3) (hABH3) (DEPC-1) (Prostate cancer antigen 1)	5	UniProt NCBI
ASCC1	Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-112126	1.86640856459e-09	1.0	ALKBH3 ASCC2 ASCC1	ALKBH3 mediated reversal of alkylation damage
REAC:R-HSA-73942	1.63310749402e-08	1.0	ALKBH3 ASCC2 ASCC1	DNA Damage Reversal
REAC:R-HSA-73943	1.63310749402e-08	1.0	ALKBH3 ASCC2 ASCC1	Reversal of alkylation damage by DNA dioxygenases
GO:0006307	5.38272230028e-06	1.0	ALKBH3 ASCC2 ASCC1	DNA dealkylation involved in DNA repair
CORUM:1377	2.05032700758e-05	0.666666666667	ASCC1 ASCC2	hASC-1 complex
GO:0035510	0.000221076094476	1.0	ALKBH3 ASCC2 ASCC1	DNA dealkylation
REAC:R-HSA-73894	0.00220643087689	1.0	ALKBH3 ASCC2 ASCC1	DNA Repair
GO:0006304	0.0028124724019	1.0	ALKBH3 ASCC2 ASCC1	DNA modification
WP:WP4931	0.0165527833611	0.333333333333	ALKBH3	Direct reversal repair

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ASCC2	ASCC1	0.999	0.18	structurally_consistent (Q8N3C0)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
ALKBH3	ASCC1	0.992	0.124		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ASCC2	ALKBH3	0.99	0.1	structurally_consistent (Q8N3C0)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116