hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12864.1
Complex Portal: CPX-15498
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RLN2 | Prorelaxin H2 [Cleaved into: Relaxin B chain; Relaxin A chain] | 5 | UniProt NCBI |
| C5orf24 | UPF0461 protein C5orf24 | 2 | UniProt NCBI |
| ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-4) | 5 | UniProt NCBI |
| CHFR | E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196) (RING-type E3 ubiquitin transferase CHFR) | 5 | UniProt NCBI |
| LRRCC1 | Leucine-rich repeat and coiled-coil domain-containing protein 1 (Centrosomal leucine-rich repeat and coiled-coil domain-containing protein) | 4 | UniProt NCBI |
| ACTN3 | Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein) | 5 | UniProt NCBI |
| ATP2C2 | Calcium-transporting ATPase type 2C member 2 (ATPase 2C2) (EC 7.2.2.10) (Ca(2+)/Mn(2+)-ATPase 2C2) (Secretory pathway Ca(2+)-transporting ATPase type 2) (SPCA2) | 5 | UniProt NCBI |
| MYH7B | Myosin-7B (Antigen MLAA-21) (Myosin cardiac muscle beta chain) (Myosin heavy chain 7B, cardiac muscle beta isoform) (Slow A MYH14) | 5 | UniProt NCBI |
| AP4B1 | AP-4 complex subunit beta-1 (AP-4 adaptor complex subunit beta) (Adaptor-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin) | 5 | UniProt NCBI |
| SETD7 | Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.364) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MYH7B | C5orf24 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| C5orf24 | ATP2C2 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| C5orf24 | ATP1A4 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| C5orf24 | CHFR | 0.996 | 0.082 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| RLN2 | ACTN3 | 0.987 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MYH7B | AP4B1 | 0.984 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| C5orf24 | ACTN3 | 0.98 | 0.028 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MYH7B | LRRCC1 | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| LRRCC1 | ATP1A4 | 0.934 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MYH7B | ATP2C2 | 0.904 | bioplex3_WMM WMM_only | ||
| ATP2C2 | ATP1A4 | 0.892 | bioplex3_WMM WMM_only | ||
| MYH7B | ACTN3 | 0.862 | bioplex_WMM bioplex3_WMM WMM_only | ||
| MYH7B | ATP1A4 | 0.855 | bioplex_WMM bioplex3_WMM WMM_only | ||
| C5orf24 | SETD7 | 0.825 | 0.064 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LRRCC1 | ACTN3 | 0.786 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ATP1A4 | ACTN3 | 0.679 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ATP2C2 | ACTN3 | 0.418 | bioplex3_WMM WMM_only | ||
| ATP2C2 | CHFR | 0.214 | bioplex3_WMM WMM_only | ||
| ATP1A4 | SETD7 | 0.092 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| CHFR | SETD7 | 0.085 | 0.074 | bioplex_WMM bioplex3_WMM WMM_only | |
| MYH7B | CHFR | 0.055 | bioplex3_WMM WMM_only | ||
| CHFR | ATP1A4 | 0.046 | bioplex3_WMM WMM_only | ||
| CHFR | ACTN3 | 0.042 | 0.032 | bioplex3_WMM WMM_only | |
| ATP2C2 | SETD7 | 0.03 | bioplex3_WMM WMM_only | ||
| MYH7B | SETD7 | 0.018 | bioplex3_WMM WMM_only | ||
| AP4B1 | SETD7 | 0.005 | 0.1 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ACTN3 | SETD7 | 0.005 | 0.026 | bioplex3_WMM WMM_only | |
| RLN2 | SETD7 | 0.004 | bioplex3_HCT116 WMM_only |
Related Complexes