hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12866.1
Complex Portal: CPX-16147
Confidence: Medium  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GALP | Galanin-like peptide | 5 | UniProt   NCBI |
| B4GALT6 | Beta-1,4-galactosyltransferase 6 (Beta-1,4-GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (EC 2.4.1.-) (Glucosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.274) (Lactosylceramide synthase) (LacCer synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6) (UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6) | 5 | UniProt   NCBI |
| AVP | Vasopressin-neurophysin 2-copeptin (AVP-NPII) [Cleaved into: Arg-vasopressin (Arginine-vasopressin); Neurophysin 2 (Neurophysin-II); Copeptin] | 5 | UniProt   NCBI |
| PCSK1 | Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Prohormone convertase 1) (Proprotein convertase 1) (PC1) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   KEGG:04080 | 0.0131637332902 | 0.666666666667 | GALP AVP | Neuroactive ligand-receptor interaction |
|   REAC:R-HSA-9036092 | 0.0498224659464 | 0.333333333333 | AVP | Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  B4GALT6 |  GALP | 0.958 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
|  AVP |  B4GALT6 | 0.955 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  B4GALT6 |  PCSK1 | 0.878 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| GALP | huMAP3_03928.1 huMAP3_10157.1 huMAP3_12866.1 huMAP3_13121.1 |
| B4GALT6 | huMAP3_03928.1 huMAP3_10157.1 huMAP3_12866.1 huMAP3_13121.1 |
| AVP | huMAP3_01414.1 huMAP3_12866.1 |
| PCSK1 | huMAP3_12866.1 huMAP3_13121.1 |