hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12918.1
Complex Portal: CPX-14264
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PIK3C2A | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha) | 5 | UniProt NCBI |
| HEATR5B | HEAT repeat-containing protein 5B | 5 | UniProt NCBI |
| CLTC | Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17) | 5 | UniProt NCBI |
| BMP2K | BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1) | 5 | UniProt NCBI |
| AFTPH | Aftiphilin | 5 | UniProt NCBI |
| MEA1 | Male-enhanced antigen 1 (MEA-1) | 3 | UniProt NCBI |
| HIP1 | Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I) | 5 | UniProt NCBI |
| AP2M1 | AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein) | 5 | UniProt NCBI |
| RALBP1 | RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (EC 7.6.2.2, EC 7.6.2.3) (Ral-interacting protein 1) | 5 | UniProt NCBI |
| SEC16A | Protein transport protein Sec16A (SEC16 homolog A) (p250) | 5 | UniProt NCBI |
| NUMB | Protein numb homolog (h-Numb) (Protein S171) | 5 | UniProt NCBI |
| AP1G1 | AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) | 5 | UniProt NCBI |
| RSKR | Ribosomal protein S6 kinase related | 1 | UniProt NCBI |
| WNK1 | Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1) | 5 | UniProt NCBI |
| AP2S1 | AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin) | 5 | UniProt NCBI |
| REPS1 | RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) | 5 | UniProt NCBI |
| KIF13A | Kinesin-like protein KIF13A (Kinesin-like protein RBKIN) | 5 | UniProt NCBI |
| GKN1 | Gastrokine-1 (18 kDa antrum mucosa protein) (AMP-18) (Protein CA11) | 5 | UniProt NCBI |
| CLINT1 | Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR) | 5 | UniProt NCBI |
| GULP1 | PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP) | 5 | UniProt NCBI |
| AP2A2 | AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Huntingtin yeast partner J) (Huntingtin-interacting protein 9) (HIP-9) (Huntingtin-interacting protein J) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) | 5 | UniProt NCBI |
| AP1M1 | AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin) | 5 | UniProt NCBI |
| STAMBPL1 | AMSH-like protease (AMSH-LP) (EC 3.4.19.-) (STAM-binding protein-like 1) | 5 | UniProt NCBI |
| ITSN2 | Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein) | 5 | UniProt NCBI |
| RUNDC3B | RUN domain-containing protein 3B (Rap2-binding protein 9) (Rap2-interacting protein 9) (RPIP-9) | 4 | UniProt NCBI |
| SEC24B | Protein transport protein Sec24B (SEC24-related protein B) | 5 | UniProt NCBI |
| TNRC6A | Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa) | 5 | UniProt NCBI |
| GAK | Cyclin-G-associated kinase (EC 2.7.11.1) | 5 | UniProt NCBI |
| AP1S3 | AP-1 complex subunit sigma-3 (Adaptor protein complex AP-1 subunit sigma-1C) (Adaptor-related protein complex 1 subunit sigma-1C) (Clathrin assembly protein complex 1 sigma-1C small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Sigma 1C subunit of AP-1 clathrin) (Sigma-adaptin 1C) (Sigma1C-adaptin) | 5 | UniProt NCBI |
| AAGAB | Alpha- and gamma-adaptin-binding protein p34 | 5 | UniProt NCBI |
| STAMBP | STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase) | 5 | UniProt NCBI |
| DNAJC6 | Auxilin (EC 3.1.3.-) (DnaJ homolog subfamily C member 6) | 5 | UniProt NCBI |
| AAK1 | AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1) | 5 | UniProt NCBI |
| EPS15L1 | Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) | 5 | UniProt NCBI |
| SYNRG | Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin) | 5 | UniProt NCBI |
| EPS15 | Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p) | 5 | UniProt NCBI |
| SMAP2 | Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like) | 5 | UniProt NCBI |
| AP1S1 | AP-1 complex subunit sigma-1A (Adaptor protein complex AP-1 subunit sigma-1A) (Adaptor-related protein complex 1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin) | 5 | UniProt NCBI |
| REPS2 | RalBP1-associated Eps domain-containing protein 2 (Partner of RalBP1) (RalBP1-interacting protein 2) | 5 | UniProt NCBI |
| AP1B1 | AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) | 5 | UniProt NCBI |
| AP2B1 | AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) | 5 | UniProt NCBI |
| CCDC32 | Coiled-coil domain-containing protein 32 | 5 | UniProt NCBI |
| AP1S2 | AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin) | 5 | UniProt NCBI |
| EPN1 | Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1) | 5 | UniProt NCBI |
| SP1 | Transcription factor Sp1 | 5 | UniProt NCBI |
| AP1AR | AP-1 complex-associated regulatory protein (2c18) (Adaptor-related protein complex 1-associated regulatory protein) (Gamma-1-adaptin brefeldin A resistance protein) (GBAR) (Gamma-BAR) (Gamma-A1-adaptin and kinesin interactor) (Gadkin) | 5 | UniProt NCBI |
| CLTCL1 | Clathrin heavy chain 2 (Clathrin heavy chain on chromosome 22) (CLH-22) | 5 | UniProt NCBI |
| PAAT | ATPase PAAT (EC 3.6.1.-) (Protein associated with ABC transporters) (PAAT) | 5 | UniProt NCBI |
| RUNDC3A | RUN domain-containing protein 3A (Rap2-interacting protein 8) (RPIP-8) | 5 | UniProt NCBI |
| COMT | Catechol O-methyltransferase (EC 2.1.1.6) | 5 | UniProt NCBI |
| AP1G2 | AP-1 complex subunit gamma-like 2 (Gamma2-adaptin) (G2ad) | 5 | UniProt NCBI |
| DENND1A | DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn) (Protein FAM31A) | 5 | UniProt NCBI |
| AMPH | Amphiphysin | 5 | UniProt NCBI |
| AP1M2 | AP-1 complex subunit mu-2 (AP-mu chain family member mu1B) (Adaptor protein complex AP-1 subunit mu-2) (Adaptor-related protein complex 1 subunit mu-2) (Clathrin assembly protein complex 1 mu-2 medium chain 2) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Mu-adaptin 2) (Mu1B-adaptin) | 5 | UniProt NCBI |
| NECAP2 | Adaptin ear-binding coat-associated protein 2 (NECAP endocytosis-associated protein 2) (NECAP-2) | 4 | UniProt NCBI |
| FCHO2 | F-BAR domain only protein 2 | 5 | UniProt NCBI |
| ZNF106 | Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) | 5 | UniProt NCBI |
| SYNJ1 | Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) | 5 | UniProt NCBI |
| ITSN1 | Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17) | 5 | UniProt NCBI |
| AP2A1 | AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit) | 5 | UniProt NCBI |
| NECAP1 | Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1) | 4 | UniProt NCBI |
| STON2 | Stonin-2 (Stoned B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030118 | 1.2905046117e-47 | 0.403225806452 | AP1B1 SYNRG AP1S3 AP1S2 EPS15 AP2S1 AP1S1 CLTC AP2M1 CLTCL1 AP1G2 AFTPH NECAP2 STON2 AP2A1 SYNJ1 AP2A2 EPS15L1 CLINT1 AP1M2 NECAP1 AP2B1 AP1G1 AP1M1 EPN1 | clathrin coat |
| GO:0048475 | 1.99883618579e-38 | 0.41935483871 | AP1B1 SYNRG AP1S3 AP1S2 EPS15 AP2S1 SYNJ1 AP1S1 CLTC AP2M1 CLTCL1 AP1G2 AFTPH NECAP2 STON2 AP2A1 SEC24B AP2A2 EPS15L1 CLINT1 AP1M2 NECAP1 AP2B1 AP1G1 AP1M1 EPN1 | coated membrane |
| GO:0030117 | 1.99883618579e-38 | 0.41935483871 | AP1B1 SYNRG AP1S3 AP1S2 EPS15 AP2S1 SYNJ1 AP1S1 CLTC AP2M1 CLTCL1 AP1G2 AFTPH NECAP2 STON2 AP2A1 SEC24B AP2A2 EPS15L1 CLINT1 AP1M2 NECAP1 AP2B1 AP1G1 AP1M1 EPN1 | membrane coat |
| GO:0030125 | 5.60766267549e-38 | 0.322580645161 | AFTPH AP2A1 AP1S3 CLINT1 AP1G2 AP1B1 AP1G1 STON2 NECAP1 AP2S1 EPN1 SYNRG AP1S2 AP1M2 AP2B1 AP2M1 AP1M1 NECAP2 AP1S1 AP2A2 | clathrin vesicle coat |
| GO:0030136 | 5.48570271259e-36 | 0.451612903226 | AP1B1 AFTPH AP2M1 AP2S1 NUMB AP2A2 AP1S3 AP1S2 FCHO2 AP1G1 HIP1 CLTC SYNRG CLTCL1 AP1G2 PIK3C2A NECAP2 STON2 AP1M2 AP2A1 AAK1 DENND1A CLINT1 AP1S1 NECAP1 AP2B1 AP1M1 EPN1 | clathrin-coated vesicle |
| GO:0030135 | 6.37788692671e-34 | 0.483870967742 | AP1B1 AFTPH AP2M1 AP2S1 NUMB AP1S3 SEC16A AP1S2 NECAP1 FCHO2 AP1G1 HIP1 CLTC SYNRG CLTCL1 AP1S1 PIK3C2A NECAP2 STON2 AP1M2 AP2A1 AAK1 SEC24B AP2A2 CLINT1 AP1G2 DENND1A AP2B1 AP1M1 EPN1 | coated vesicle |
| REAC:R-HSA-199991 | 6.49095792261e-34 | 0.596774193548 | AP1B1 AP2M1 HIP1 AP1G1 AMPH ITSN1 AP1S3 NECAP2 SEC16A AP2A2 NECAP1 EPS15 GAK SYNJ1 ITSN2 CLTC FCHO2 AAK1 AP1S1 PIK3C2A AP2S1 REPS1 STON2 REPS2 AP1M2 AP2A1 CLTCL1 SEC24B AP1S2 DNAJC6 CLINT1 AP1G2 DENND1A AP2B1 EPS15L1 AP1M1 EPN1 | Membrane Trafficking |
| REAC:R-HSA-8856828 | 4.60434606925e-33 | 0.403225806452 | FCHO2 AP2S1 AMPH ITSN1 AP2A2 EPS15L1 GAK ITSN2 CLTC AP2M1 CLTCL1 PIK3C2A NECAP2 DNAJC6 REPS1 STON2 REPS2 AP2A1 AAK1 SYNJ1 HIP1 NECAP1 AP2B1 EPS15 EPN1 | Clathrin-mediated endocytosis |
| REAC:R-HSA-5653656 | 4.8898551429e-33 | 0.596774193548 | AP1B1 AP2M1 HIP1 AP1G1 AMPH ITSN1 AP1S3 NECAP2 SEC16A AP2A2 NECAP1 EPS15 GAK SYNJ1 ITSN2 CLTC FCHO2 AAK1 AP1S1 PIK3C2A AP2S1 REPS1 STON2 REPS2 AP1M2 AP2A1 CLTCL1 SEC24B AP1S2 DNAJC6 CLINT1 AP1G2 DENND1A AP2B1 EPS15L1 AP1M1 EPN1 | Vesicle-mediated transport |
| GO:0030131 | 1.01203235716e-32 | 0.258064516129 | AFTPH AP2A1 AP1S3 AP2A2 AP1B1 AP1G1 STON2 AP2S1 AP1G2 SYNRG AP1M2 AP2B1 AP2M1 AP1M1 AP1S1 AP1S2 | clathrin adaptor complex |
| GO:0030120 | 3.19699959993e-32 | 0.338709677419 | AFTPH AP2A1 AP1S3 CLINT1 AP1G2 AP1B1 AP1G1 STON2 NECAP1 AP2S1 AP1S1 SYNRG AP1S2 AP1M2 EPN1 AP2B1 AP2M1 AP1M1 NECAP2 SEC24B AP2A2 | vesicle coat |
| GO:0016192 | 3.77251252315e-31 | 0.709677419355 | AP1B1 HEATR5B AP2M1 HIP1 AP1AR AMPH RALBP1 AP1S3 NECAP2 BMP2K CCDC32 AP2A2 NECAP1 AP1G1 GAK SYNJ1 ITSN2 CLTC FCHO2 KIF13A AP1S1 PIK3C2A AP2S1 SEC16A REPS1 STON2 REPS2 AP1M2 AP2A1 DENND1A GULP1 AAK1 ITSN1 SEC24B AP1S2 DNAJC6 CLINT1 AP1G2 CLTCL1 AP2B1 EPS15L1 AP1M1 EPN1 EPS15 | vesicle-mediated transport |
| GO:0030665 | 3.5655759932e-29 | 0.354838709677 | AP1B1 SYNRG AP1S3 AP1S2 AP1G1 AP2S1 AP1S1 CLTC AP2M1 AP2A2 AP1G2 AFTPH NECAP2 STON2 AP2A1 DENND1A CLINT1 AP1M2 NECAP1 AP2B1 AP1M1 EPN1 | clathrin-coated vesicle membrane |
| GO:0030662 | 5.71946008267e-28 | 0.387096774194 | AP1B1 SYNRG AP1S3 SEC16A AP1S2 AP1G1 AP2S1 CLTC AP2M1 AP2A2 AP1G2 AFTPH NECAP2 STON2 AP1M2 AP2A1 SEC24B DENND1A CLINT1 AP1S1 NECAP1 AP2B1 AP1M1 EPN1 | coated vesicle membrane |
| GO:0006897 | 2.11159084371e-27 | 0.516129032258 | CCDC32 AP2M1 HIP1 AMPH ITSN1 RALBP1 NECAP2 BMP2K AP2A2 EPS15 GAK ITSN2 CLTC FCHO2 AAK1 HEATR5B AP1S1 PIK3C2A AP2S1 REPS1 STON2 REPS2 AP2A1 CLTCL1 SYNJ1 DENND1A DNAJC6 CLINT1 AP2B1 EPS15L1 GULP1 EPN1 | endocytosis |
| GO:0030119 | 2.5531846918e-25 | 0.258064516129 | AFTPH AP2A1 AP1S3 AP2A2 AP1B1 AP1G1 STON2 AP2S1 AP1G2 SYNRG AP1M2 AP2B1 AP2M1 AP1M1 AP1S1 AP1S2 | AP-type membrane coat adaptor complex |
| REAC:R-HSA-8856825 | 4.34049143212e-25 | 0.306451612903 | AP2A1 AP2B1 NECAP1 AP2A2 REPS2 FCHO2 AP2M1 STON2 REPS1 AP2S1 ITSN2 NECAP2 CLTCL1 CLTC EPS15L1 AAK1 ITSN1 EPN1 EPS15 | Cargo recognition for clathrin-mediated endocytosis |
| GO:0005905 | 3.89427881944e-24 | 0.258064516129 | CCDC32 AP2A1 AP2A2 FCHO2 AP2M1 STON2 AP2S1 REPS1 CLTCL1 NECAP2 AP2B1 EPS15L1 AAK1 ITSN1 SYNJ1 EPS15 | clathrin-coated pit |
| GO:0098657 | 1.1453008499e-23 | 0.516129032258 | CCDC32 AP2M1 HIP1 AMPH ITSN1 RALBP1 NECAP2 BMP2K AP2A2 EPS15 GAK ITSN2 CLTC FCHO2 AAK1 HEATR5B AP1S1 PIK3C2A AP2S1 REPS1 STON2 REPS2 AP2A1 CLTCL1 SYNJ1 DENND1A DNAJC6 CLINT1 AP2B1 EPS15L1 GULP1 EPN1 | import into cell |
| REAC:R-HSA-164938 | 1.1933413352e-21 | 0.193548387097 | AP1G1 AP2A1 AP2A2 AP1B1 AP2M1 AP2S1 AP1M2 AP2B1 AP1M1 AP1S3 AP1S1 AP1S2 | Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| GO:0072583 | 1.21198156437e-21 | 0.241935483871 | BMP2K CCDC32 AP2A2 DNAJC6 AP2M1 STON2 AP2A1 AP2S1 GAK ITSN2 CLTC FCHO2 AAK1 ITSN1 AP2B1 | clathrin-dependent endocytosis |
| GO:0030130 | 1.87438080669e-21 | 0.177419354839 | AFTPH AP1S2 AP1B1 SYNRG AP1G2 AP1G1 AP1M2 AP2A1 AP1S3 AP1M1 AP1S1 | clathrin coat of trans-Golgi network vesicle |
| GO:0030121 | 4.40116128452e-20 | 0.161290322581 | AFTPH AP1S2 AP1B1 SYNRG AP1G2 AP1G1 AP1M2 AP1S3 AP1M1 AP1S1 | AP-1 adaptor complex |
| GO:0035615 | 5.64927645501e-20 | 0.177419354839 | AP2A2 AP2M1 STON2 AP2S1 HIP1 AP1M2 AP2B1 AP1G1 AP1M1 AP1G2 AP2A1 | clathrin adaptor activity |
| GO:0012510 | 5.64927645501e-20 | 0.177419354839 | AFTPH AP1S2 AP1B1 SYNRG AP1G2 AP1G1 AP1M2 AP2A1 AP1S3 AP1M1 AP1S1 | trans-Golgi network transport vesicle membrane |
| REAC:R-HSA-164952 | 6.92490759235e-20 | 0.193548387097 | AP1G1 AP2A1 AP2A2 AP1B1 AP2M1 AP2S1 AP1M2 AP2B1 AP1M1 AP1S3 AP1S1 AP1S2 | The role of Nef in HIV-1 replication and disease pathogenesis |
| CORUM:144 | 1.14423926169e-19 | 0.145161290323 | AP1B1 AP1S2 AP1G1 AP1G2 AP1AR AP1M2 AP1M1 AP1S3 AP1S1 | Gamma-BAR-AP1 complex |
| GO:0140312 | 2.11169621526e-19 | 0.177419354839 | AP2A2 AP2M1 STON2 AP2S1 HIP1 AP1M2 AP2B1 AP1G1 AP1M1 AP1G2 AP2A1 | cargo adaptor activity |
| REAC:R-HSA-199992 | 7.80719533656e-18 | 0.225806451613 | AP1B1 PIK3C2A CLINT1 DNAJC6 AP1G1 GAK AP1G2 NECAP1 AP1M2 CLTC AP1S3 AP1M1 AP1S1 AP1S2 | trans-Golgi Network Vesicle Budding |
| GO:0006810 | 1.80727984689e-17 | 0.758064516129 | AP1B1 AFTPH AP2M1 HIP1 AP1AR AMPH RALBP1 AP1S3 WNK1 NECAP2 SEC16A CCDC32 AP2A2 NECAP1 FCHO2 AP1G1 GAK SYNJ1 ITSN2 CLTC SYNRG KIF13A HEATR5B AP1S1 PIK3C2A AP2S1 BMP2K REPS1 STON2 REPS2 AP1M2 AP2A1 DENND1A GULP1 AAK1 ITSN1 SEC24B AP1S2 DNAJC6 CLINT1 AP1G2 CLTCL1 AP2B1 EPS15L1 AP1M1 EPN1 EPS15 | transport |
| CORUM:36 | 3.09516720287e-17 | 0.129032258065 | AP1B1 AP1S2 AP1G1 AP1G2 AP1M2 AP1M1 AP1S3 AP1S1 | AP1 adaptor complex |
| GO:0006898 | 7.71740695119e-17 | 0.306451612903 | BMP2K CCDC32 CLTCL1 AP2A2 DNAJC6 FCHO2 AP2M1 STON2 GAK AP2S1 AP2A1 HIP1 ITSN2 CLTC EPS15 AAK1 ITSN1 AP1S1 AP2B1 | receptor-mediated endocytosis |
| GO:0097708 | 2.7312908019e-16 | 0.612903225806 | AP1B1 AFTPH AP2M1 AP2S1 NUMB AMPH ITSN1 AP1S3 SEC16A AP2A2 NECAP1 FCHO2 AP1G1 HIP1 ITSN2 CLTC SYNRG AAK1 HEATR5B AP1S1 PIK3C2A NECAP2 STON2 AP1M2 AP2A1 DENND1A KIF13A SEC24B AP1S2 STAMBP CLINT1 AP1AR STAMBPL1 AP1G2 CLTCL1 AP2B1 AP1M1 EPN1 | intracellular vesicle |
| GO:0051234 | 9.72567744049e-16 | 0.758064516129 | AP1B1 AFTPH AP2M1 HIP1 AP1AR AMPH RALBP1 AP1S3 WNK1 NECAP2 SEC16A CCDC32 AP2A2 NECAP1 FCHO2 AP1G1 GAK SYNJ1 ITSN2 CLTC SYNRG KIF13A HEATR5B AP1S1 PIK3C2A AP2S1 BMP2K REPS1 STON2 REPS2 AP1M2 AP2A1 DENND1A GULP1 AAK1 ITSN1 SEC24B AP1S2 DNAJC6 CLINT1 AP1G2 CLTCL1 AP2B1 EPS15L1 AP1M1 EPN1 EPS15 | establishment of localization |
| REAC:R-HSA-432722 | 1.25430961614e-15 | 0.193548387097 | AP1B1 PIK3C2A CLINT1 DNAJC6 AP1G1 GAK AP1M2 NECAP1 AP1S3 AP1M1 AP1S1 AP1S2 | Golgi Associated Vesicle Biogenesis |
| GO:0030132 | 2.64230758795e-15 | 0.145161290323 | AP2A1 EPS15L1 AP2M1 AP2S1 STON2 AP2B1 EPS15 SYNJ1 AP2A2 | clathrin coat of coated pit |
| GO:0030140 | 3.18643976008e-15 | 0.177419354839 | AFTPH AP1S2 AP1B1 SYNRG AP1G2 AP1G1 AP1M2 AP2A1 AP1S3 AP1M1 AP1S1 | trans-Golgi network transport vesicle |
| REAC:R-HSA-2132295 | 1.60695696169e-14 | 0.225806451613 | AP1B1 AP2A1 AP1S3 AP2A2 AP2M1 AP2S1 AP1S1 AP1S2 AP1M2 CLTC AP1G1 AP1M1 SEC24B AP2B1 | MHC class II antigen presentation |
| REAC:R-HSA-432720 | 2.8862099606e-14 | 0.161290322581 | DNAJC6 AP1S2 AP1B1 AP1G1 AP1G2 AP1M2 CLTC AP1M1 AP1S3 AP1S1 | Lysosome Vesicle Biogenesis |
| GO:0031410 | 3.56711147095e-14 | 0.58064516129 | AP1B1 AFTPH AP2M1 AP2S1 NUMB AMPH AP1S3 SEC16A AP2A2 NECAP1 FCHO2 AP1G1 HIP1 CLTCL1 CLTC SYNRG AAK1 HEATR5B AP1S1 PIK3C2A NECAP2 STON2 AP1M2 AP2A1 KIF13A SEC24B AP1S2 STAMBP CLINT1 AP1AR STAMBPL1 AP1G2 DENND1A AP2B1 AP1M1 EPN1 | cytoplasmic vesicle |
| GO:0051179 | 7.00426401281e-14 | 0.774193548387 | AP1B1 AFTPH AP2M1 HIP1 NUMB AMPH AP1S3 RALBP1 WNK1 NECAP2 SEC16A CCDC32 AP2A2 NECAP1 FCHO2 AP1G1 GAK SYNJ1 ITSN2 CLTC SYNRG KIF13A HEATR5B AP1S1 PIK3C2A AP2S1 BMP2K REPS1 STON2 REPS2 AP1M2 AP2A1 DENND1A GULP1 AAK1 ITSN1 SEC24B AP1S2 DNAJC6 CLINT1 AP1AR AP1G2 CLTCL1 AP2B1 EPS15L1 AP1M1 EPN1 EPS15 | localization |
| GO:0012506 | 5.30361208447e-13 | 0.41935483871 | AP1B1 SYNRG AP2A2 AP1S3 SEC16A AP1S2 AP1G1 AP2S1 SYNJ1 CLTC AP2M1 KIF13A AP1G2 AFTPH NECAP2 STON2 AP1M2 AP2A1 SEC24B DENND1A CLINT1 AP1S1 NECAP1 AP2B1 AP1M1 EPN1 | vesicle membrane |
| REAC:R-HSA-164940 | 7.90366681766e-13 | 0.112903225806 | AP1B1 AP1S2 AP1G1 AP1M2 AP1M1 AP1S3 AP1S1 | Nef mediated downregulation of MHC class I complex cell surface expression |
| GO:0030660 | 1.4262129012e-12 | 0.177419354839 | AFTPH AP1S2 AP1B1 SYNRG AP1G2 AP1G1 AP1M2 AP2A1 AP1S3 AP1M1 AP1S1 | Golgi-associated vesicle membrane |
| GO:0140238 | 1.4262129012e-12 | 0.177419354839 | DNAJC6 AP2M1 STON2 GAK AP2S1 ITSN2 AP2B1 FCHO2 ITSN1 SYNJ1 AMPH | presynaptic endocytosis |
| GO:0048488 | 1.4262129012e-12 | 0.177419354839 | DNAJC6 AP2M1 STON2 GAK AP2S1 ITSN2 AP2B1 FCHO2 ITSN1 SYNJ1 AMPH | synaptic vesicle endocytosis |
| GO:0051649 | 1.79692677443e-12 | 0.516129032258 | AFTPH AP2M1 AP2S1 AP1AR AMPH ITSN1 WNK1 SEC16A AP2A2 FCHO2 EPS15L1 GAK SYNJ1 ITSN2 CLTC SYNRG KIF13A AP1G2 HEATR5B REPS1 STON2 REPS2 AP2A1 CLTCL1 SEC24B DENND1A DNAJC6 AP1M2 AP2B1 AP1G1 AP1M1 EPS15 | establishment of localization in cell |
| GO:0098796 | 4.70413519538e-12 | 0.435483870968 | AP1B1 AFTPH AP2M1 AP1G1 AP1S3 AP1S2 EPS15 AP2S1 SYNJ1 CLTC SYNRG CLTCL1 AP1M2 PIK3C2A NECAP2 STON2 AP2A1 SEC24B AP2A2 CLINT1 AP1G2 AP1S1 NECAP1 AP2B1 EPS15L1 AP1M1 EPN1 | membrane protein complex |
| GO:0030659 | 4.83462222465e-12 | 0.403225806452 | AP1B1 SYNRG AP2A2 AP1S3 SEC16A AP1S2 AP1G1 AP2S1 CLTC AP2M1 KIF13A AP1G2 AFTPH NECAP2 STON2 AP1M2 AP2A1 SEC24B DENND1A CLINT1 AP1S1 NECAP1 AP2B1 AP1M1 EPN1 | cytoplasmic vesicle membrane |
| GO:0036465 | 1.30664241819e-11 | 0.177419354839 | DNAJC6 AP2M1 STON2 GAK AP2S1 ITSN2 AP2B1 FCHO2 ITSN1 SYNJ1 AMPH | synaptic vesicle recycling |
| GO:0099003 | 2.86657616564e-11 | 0.209677419355 | DNAJC6 AP2A1 AP2A2 AP2M1 STON2 GAK AP2S1 ITSN2 AP2B1 FCHO2 ITSN1 SYNJ1 AMPH | vesicle-mediated transport in synapse |
| GO:0031982 | 4.40540209396e-11 | 0.677419354839 | AP1B1 AFTPH AP2M1 HIP1 NUMB AMPH ITSN1 AP1S3 NECAP2 SEC16A AP2A2 NECAP1 FCHO2 AP1G1 GAK SYNJ1 SYNRG ITSN2 CLTC STAMBP AAK1 HEATR5B AP1S1 PIK3C2A AP2S1 STON2 AP1M2 AP2A1 DENND1A KIF13A SEC24B AP1S2 DNAJC6 CLINT1 AP1G2 AP1AR STAMBPL1 COMT CLTCL1 AP2B1 AP1M1 EPN1 | vesicle |
| KEGG:04144 | 4.76558362667e-11 | 0.225806451613 | DNAJC6 AP2A1 SMAP2 EPS15L1 AP2A2 AP2B1 STAMBP AP2S1 AMPH CLTC AP2M1 CLTCL1 EPN1 EPS15 | Endocytosis |
| REAC:R-HSA-162909 | 5.14113233686e-11 | 0.193548387097 | AP1G1 AP2A1 AP2A2 AP1B1 AP2M1 AP2S1 AP1M2 AP2B1 AP1M1 AP1S3 AP1S1 AP1S2 | Host Interactions of HIV factors |
| GO:0030276 | 5.83754736728e-11 | 0.161290322581 | PIK3C2A CLINT1 AFTPH HIP1 GAK CLTC CLTCL1 DNAJC6 EPN1 AP2B1 | clathrin binding |
| GO:0030658 | 6.65345068489e-11 | 0.209677419355 | AP1B1 AFTPH AP1S2 AP1G2 SEC16A AP1G1 AP1S1 SYNRG AP1M2 AP2A1 AP1S3 AP1M1 SEC24B | transport vesicle membrane |
| GO:0051641 | 7.63601881842e-11 | 0.612903225806 | AP1B1 AFTPH AP2M1 HIP1 NUMB AMPH ITSN1 AP1S3 WNK1 SEC16A AP2A2 FCHO2 EPS15L1 GAK SYNJ1 ITSN2 CLTC SYNRG AAK1 AP1S1 HEATR5B AP2S1 REPS1 STON2 REPS2 AP1M2 AP2A1 KIF13A SEC24B DENND1A DNAJC6 CLTCL1 AP1AR AP1G2 AP2B1 AP1G1 AP1M1 EPS15 | cellular localization |
| WP:WP437 | 1.02730581237e-10 | 0.193548387097 | AP2A1 STAMBP AP2M1 AP2S1 SP1 REPS2 AP2B1 EPS15L1 RALBP1 SYNJ1 EPN1 EPS15 | EGF EGFR signaling pathway |
| GO:0005798 | 2.37241786867e-10 | 0.177419354839 | AFTPH AP1S2 AP1B1 SYNRG AP1G2 AP1G1 AP1M2 AP2A1 AP1S3 AP1M1 AP1S1 | Golgi-associated vesicle |
| GO:0030133 | 2.55468303139e-10 | 0.258064516129 | AP1B1 AFTPH AP1S2 AP1G2 SEC16A AP1G1 STON2 AP1S1 SYNRG AP1AR AP1M2 AMPH AP1S3 AP1M1 SEC24B AP2A1 | transport vesicle |
| GO:0048268 | 1.46600844858e-09 | 0.112903225806 | PIK3C2A EPS15 AP2S1 GAK HIP1 CLTC FCHO2 | clathrin coat assembly |
| REAC:R-HSA-177504 | 1.57208366829e-09 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | Retrograde neurotrophin signalling |
| REAC:R-HSA-5140745 | 2.90999175181e-09 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | WNT5A-dependent internalization of FZD2, FZD5 and ROR2 |
| GO:0030128 | 6.32339020868e-09 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 STON2 AP2A1 AP2B1 | clathrin coat of endocytic vesicle |
| GO:0030122 | 6.32339020868e-09 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 STON2 AP2A1 AP2B1 | AP-2 adaptor complex |
| KEGG:04142 | 7.16926802642e-09 | 0.161290322581 | AP1B1 AP1S2 AP1G1 AP1G2 CLTCL1 AP1M2 CLTC AP1M1 AP1S3 AP1S1 | Lysosome |
| REAC:R-HSA-5099900 | 8.43179763981e-09 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | WNT5A-dependent internalization of FZD4 |
| REAC:R-HSA-182218 | 9.27994422617e-09 | 0.0806451612903 | AP2M1 AP2A1 AP2B1 AP2S1 AP2A2 | Nef Mediated CD8 Down-regulation |
| REAC:R-HSA-8866427 | 1.34465535879e-08 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | VLDLR internalisation and degradation |
| GO:0012505 | 2.02002256785e-08 | 0.661290322581 | AP1B1 AFTPH AP2M1 STON2 HIP1 AP1AR AMPH ITSN1 AP1S3 NECAP2 SEC16A CCDC32 AP2A2 FCHO2 EPS15L1 GAK SYNJ1 SYNRG CLTCL1 CLTC STAMBP AAK1 AP1S1 GKN1 PIK3C2A AP2S1 REPS1 TNRC6A AP1M2 AP2A1 KIF13A SEC24B AP1S2 CLINT1 STAMBPL1 AP1G2 AP2B1 AP1G1 AP1M1 EPN1 EPS15 | endomembrane system |
| GO:0099504 | 2.88657315169e-08 | 0.177419354839 | DNAJC6 AP2M1 STON2 GAK AP2S1 ITSN2 AP2B1 FCHO2 ITSN1 SYNJ1 AMPH | synaptic vesicle cycle |
| REAC:R-HSA-8964038 | 3.0967074637e-08 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | LDL clearance |
| REAC:R-HSA-162906 | 4.49367021877e-08 | 0.193548387097 | AP1G1 AP2A1 AP2A2 AP1B1 AP2M1 AP2S1 AP1M2 AP2B1 AP1M1 AP1S3 AP1S1 AP1S2 | HIV Infection |
| REAC:R-HSA-167590 | 5.53182339344e-08 | 0.0806451612903 | AP2M1 AP2A1 AP2B1 AP2S1 AP2A2 | Nef Mediated CD4 Down-regulation |
| WP:WP2267 | 6.86899444874e-08 | 0.112903225806 | AP2A1 AP2A2 AP2M1 AP2S1 AP2B1 CLTCL1 CLTC | Synaptic vesicle pathway |
| KEGG:04961 | 7.5275903163e-08 | 0.112903225806 | AP2A1 AP2A2 AP2M1 AP2S1 AP2B1 CLTCL1 CLTC | Endocrine and other factor-regulated calcium reabsorption |
| GO:0005829 | 9.51043663284e-08 | 0.741935483871 | AP1B1 AFTPH AP2M1 STON2 HIP1 AMPH RALBP1 AP1S3 WNK1 SEC16A AP2A2 NECAP1 FCHO2 AP1G1 GAK SYNJ1 ITSN2 CLTC STAMBP AAK1 HEATR5B AP1S1 PIK3C2A AP2S1 AAGAB TNRC6A REPS1 REPS2 AP1M2 AP2A1 CLTCL1 AP1S2 ITSN1 SEC24B SMAP2 DNAJC6 CLINT1 ZNF106 STAMBPL1 COMT DENND1A AP2B1 EPS15L1 AP1M1 EPN1 EPS15 | cytosol |
| CORUM:7476 | 1.38475185333e-07 | 0.0645161290323 | AP1M1 AP1S1 AP1G2 AP1B1 | AP1B1-AP1G2-AP1M-1AP1S1 complex |
| CORUM:247 | 1.38475185333e-07 | 0.0645161290323 | RALBP1 AP2A1 EPN1 NUMB | RalBP1-CCNB1-AP2A-NUMB-EPN1 complex |
| GO:0032588 | 2.17450664439e-07 | 0.161290322581 | AFTPH AP1S2 AP1B1 AP1G1 AP1M2 KIF13A CLTC AP1M1 AP1S3 AP1S1 | trans-Golgi network membrane |
| REAC:R-HSA-3928665 | 2.25603554349e-07 | 0.112903225806 | AP2A1 AP2A2 AP2M1 AP2S1 AP2B1 CLTCL1 CLTC | EPH-ephrin mediated repulsion of cells |
| REAC:R-HSA-437239 | 3.13040861822e-07 | 0.112903225806 | AP2A1 AP2A2 AP2M1 AP2S1 NUMB CLTC AP2B1 | Recycling pathway of L1 |
| KEGG:04721 | 4.42840370244e-07 | 0.112903225806 | AP2A1 AP2A2 AP2M1 AP2S1 AP2B1 CLTCL1 CLTC | Synaptic vesicle cycle |
| REAC:R-HSA-2682334 | 6.99546104879e-07 | 0.129032258065 | AP2A1 AP2A2 AP2M1 AP2S1 AP2B1 ITSN1 CLTCL1 CLTC | EPH-Ephrin signaling |
| GO:0140239 | 1.21567269363e-06 | 0.0806451612903 | AP2M1 AP2A1 AP2B1 AP2S1 AP2A2 | postsynaptic endocytosis |
| GO:0098884 | 1.21567269363e-06 | 0.0806451612903 | AP2M1 AP2A1 AP2B1 AP2S1 AP2A2 | postsynaptic neurotransmitter receptor internalization |
| REAC:R-HSA-8964043 | 1.44358474823e-06 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | Plasma lipoprotein clearance |
| GO:0005768 | 2.53608822808e-06 | 0.306451612903 | AP1AR AP1B1 STAMBPL1 AP2B1 AP1S3 CLINT1 EPN1 AP2M1 AP2A1 AP2S1 AP1M1 AP1S2 CLTCL1 CLTC AP1G1 STAMBP KIF13A AP1S1 AP2A2 | endosome |
| GO:1903232 | 4.05668677745e-06 | 0.0967741935484 | AP1B1 AP1S2 AP1G1 AP1M1 AP1S3 AP1S1 | melanosome assembly |
| GO:0036020 | 4.05668677745e-06 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | endolysosome membrane |
| GO:0005802 | 4.76160498423e-06 | 0.193548387097 | AP1B1 PIK3C2A AP1S3 AP1S2 AFTPH AP1G1 AP1M2 CLTCL1 CLTC KIF13A AP1M1 AP1S1 | trans-Golgi network |
| WP:WP4159 | 6.41336950862e-06 | 0.0806451612903 | AP2M1 AP2A1 AP2B1 AP2S1 AP2A2 | GABA receptor signaling |
| GO:0048753 | 6.61026517707e-06 | 0.112903225806 | AP1B1 AP1S2 AP1G1 KIF13A AP1S3 AP1M1 AP1S1 | pigment granule organization |
| GO:0032438 | 6.61026517707e-06 | 0.112903225806 | AP1B1 AP1S2 AP1G1 KIF13A AP1S3 AP1M1 AP1S1 | melanosome organization |
| REAC:R-HSA-9824446 | 9.10044750614e-06 | 0.258064516129 | AP1B1 AP2A1 AP1S3 AP2A2 SP1 AP2M1 COMT AP2S1 AP1S1 AP1S2 AP1M2 CLTC AP1G1 AP1M1 SEC24B AP2B1 | Viral Infection Pathways |
| GO:0046907 | 1.04462285938e-05 | 0.354838709677 | AFTPH SYNRG AP1AR ITSN1 WNK1 SEC16A DENND1A EPS15L1 GAK ITSN2 CLTC CLTCL1 AP1G2 HEATR5B REPS1 REPS2 AP2A1 KIF13A SEC24B AP1G1 AP1M1 EPS15 | intracellular transport |
| GO:0060155 | 1.17415212988e-05 | 0.0967741935484 | AP1B1 AP1S2 AP1G1 AP1M1 AP1S3 AP1S1 | platelet dense granule organization |
| GO:0098588 | 1.23886738176e-05 | 0.403225806452 | AP1B1 SYNRG AP2A2 AP1S3 SEC16A AP1S2 AP1G1 AP2S1 CLTC AP2M1 KIF13A AP1G2 AFTPH NECAP2 STON2 AP1M2 AP2A1 SEC24B DENND1A CLINT1 AP1S1 NECAP1 AP2B1 AP1M1 EPN1 | bounding membrane of organelle |
| GO:0110010 | 1.46783696453e-05 | 0.0645161290323 | AP1G1 AP1M2 AP1S1 AP1B1 | basolateral protein secretion |
| GO:0005794 | 2.35626101599e-05 | 0.354838709677 | AP1B1 AFTPH SYNRG HIP1 AP1AR AP1S3 SEC16A AP1S2 AP1G1 GAK AP1S1 CLTC CLTCL1 AP1G2 GKN1 PIK3C2A TNRC6A AP2A1 KIF13A CLINT1 AP1M2 AP1M1 | Golgi apparatus |
| REAC:R-HSA-5663205 | 2.55256831213e-05 | 0.274193548387 | AP1B1 AP2A1 AP2B1 AP1S3 AP2A2 SP1 AP2M1 COMT AP2S1 AP1S1 AP1S2 AP1M2 CLTC AP1G1 AP1M1 SEC24B EPS15 | Infectious disease |
| GO:0098791 | 3.0641828416e-05 | 0.193548387097 | AP1B1 PIK3C2A AP1S3 AP1S2 AFTPH AP1G1 AP1M2 CLTCL1 CLTC KIF13A AP1M1 AP1S1 | Golgi apparatus subcompartment |
| GO:0045334 | 3.56026726891e-05 | 0.129032258065 | AP2A1 AP2A2 AP2M1 AP2S1 STON2 AP2B1 CLTCL1 CLTC | clathrin-coated endocytic vesicle |
| GO:0098852 | 4.14570557557e-05 | 0.209677419355 | AP1B1 AP2A1 AP1S3 AP2A2 AP2M1 AP2S1 AP1M2 AP1S2 CLTC AP1G1 AP1M1 AP1S1 AP2B1 | lytic vacuole membrane |
| GO:0005765 | 4.14570557557e-05 | 0.209677419355 | AP1B1 AP2A1 AP1S3 AP2A2 AP2M1 AP2S1 AP1M2 AP1S2 CLTC AP1G1 AP1M1 AP1S1 AP2B1 | lysosomal membrane |
| GO:0016020 | 4.24274203099e-05 | 0.774193548387 | AP1B1 AFTPH AP2M1 HIP1 NUMB AMPH RALBP1 AP1S3 WNK1 NECAP2 SEC16A CCDC32 AP2A2 NECAP1 FCHO2 AP1G1 GAK SYNJ1 SYNRG ITSN2 CLTC STAMBP KIF13A HEATR5B AP1S1 PIK3C2A AP2S1 REPS1 STON2 REPS2 AP1M2 AP2A1 DENND1A AAK1 ITSN1 SEC24B AP1S2 CLINT1 AP1G2 ZNF106 STAMBPL1 COMT CLTCL1 AP2B1 EPS15L1 AP1M1 EPN1 EPS15 | membrane |
| GO:0099590 | 4.51078517047e-05 | 0.0806451612903 | AP2M1 AP2A1 AP2B1 AP2S1 AP2A2 | neurotransmitter receptor internalization |
| GO:0036019 | 6.27978277974e-05 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | endolysosome |
| REAC:R-HSA-174824 | 7.27347791401e-05 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | Plasma lipoprotein assembly, remodeling, and clearance |
| REAC:R-HSA-373760 | 8.97740154343e-05 | 0.112903225806 | AP2A1 AP2A2 AP2M1 AP2S1 NUMB CLTC AP2B1 | L1CAM interactions |
| GO:0005774 | 0.000105417260932 | 0.209677419355 | AP1B1 AP2A1 AP1S3 AP2A2 AP2M1 AP2S1 AP1M2 AP1S2 CLTC AP1G1 AP1M1 AP1S1 AP2B1 | vacuolar membrane |
| KEGG:05170 | 0.00011517568212 | 0.129032258065 | AP1B1 AP1S2 AP1G1 AP1G2 AP1M2 AP1M1 AP1S3 AP1S1 | Human immunodeficiency virus 1 infection |
| GO:0033059 | 0.000150923696882 | 0.112903225806 | AP1B1 AP1S2 AP1G1 KIF13A AP1S3 AP1M1 AP1S1 | cellular pigmentation |
| KEGG:05016 | 0.000152800164513 | 0.145161290323 | AP2A1 AP2A2 SP1 AP2M1 AP2S1 HIP1 CLTC CLTCL1 AP2B1 | Huntington disease |
| HPA:0100212 | 0.000156136016549 | 0.41935483871 | AP1B1 SYNRG HIP1 AMPH RALBP1 BMP2K AP2A2 EPS15 GAK SYNJ1 ITSN2 CLTC AAK1 AP1G2 AP1G1 AAGAB REPS1 TNRC6A AP2A1 SEC24B DNAJC6 CLINT1 AP2B1 EPS15L1 GULP1 EPN1 | cerebral cortex; neuropil[>=Medium] |
| REAC:R-HSA-1280218 | 0.000204013916042 | 0.225806451613 | AP1B1 AP2A1 AP1S3 AP2A2 AP2M1 AP2S1 AP1S1 AP1S2 AP1M2 CLTC AP1G1 AP1M1 SEC24B AP2B1 | Adaptive Immune System |
| GO:0030669 | 0.000282532156216 | 0.112903225806 | AP2A2 AP2M1 AP2S1 STON2 AP2A1 CLTC AP2B1 | clathrin-coated endocytic vesicle membrane |
| GO:0006892 | 0.000299418323379 | 0.129032258065 | SEC16A EPS15 GAK AP1AR AP2A1 AP1G1 KIF13A AP1G2 | post-Golgi vesicle-mediated transport |
| GO:0033363 | 0.0005648540015 | 0.0967741935484 | AP1B1 AP1S2 AP1G1 AP1M1 AP1S3 AP1S1 | secretory granule organization |
| REAC:R-HSA-9679191 | 0.000585252911825 | 0.0967741935484 | COMT AP2M1 AP2S1 AP2A1 AP2A2 AP2B1 | Potential therapeutics for SARS |
| REAC:R-HSA-3858494 | 0.000634137782832 | 0.112903225806 | AP2A1 AP2A2 AP2M1 TNRC6A AP2S1 AP2B1 CLTC | Beta-catenin independent WNT signaling |
| HPA:0100211 | 0.000852985276233 | 0.58064516129 | AP1B1 SYNRG STON2 HIP1 NUMB AMPH RALBP1 AP1S3 BMP2K AP2A2 AP1G1 GAK SYNJ1 ITSN2 CLTC AAK1 AP1S1 MEA1 WNK1 AAGAB REPS1 TNRC6A AP2A1 SEC24B SMAP2 DNAJC6 CLINT1 AP1G2 AP1AR SP1 COMT AP2B1 EPS15L1 GULP1 EPN1 EPS15 | cerebral cortex; neuropil[>=Low] |
| REAC:R-HSA-4086400 | 0.000874550287482 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | PCP/CE pathway |
| WP:WP4549 | 0.000952730527894 | 0.0967741935484 | CLTC AP2M1 AP2S1 AP2A1 CLTCL1 AP2B1 | Fragile X syndrome |
| GO:0043473 | 0.0011418878617 | 0.112903225806 | AP1B1 AP1S2 AP1G1 KIF13A AP1S3 AP1M1 AP1S1 | pigmentation |
| GO:0016050 | 0.00116308524383 | 0.177419354839 | AP1G1 AP1S2 AP1B1 AP2M1 AP1S1 KIF13A AP1M1 AP1S3 SYNJ1 SEC24B EPS15 | vesicle organization |
| REAC:R-HSA-187037 | 0.00127118422684 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | Signaling by NTRK1 (TRKA) |
| GO:0016482 | 0.00178484178507 | 0.129032258065 | HEATR5B EPS15 GAK AP1AR CLTC AP1G1 CLTCL1 AP2A1 | cytosolic transport |
| REAC:R-HSA-166520 | 0.00324427030102 | 0.0967741935484 | AP2A2 AP2M1 AP2S1 AP2A1 CLTC AP2B1 | Signaling by NTRKs |
| GO:0016197 | 0.00351358689412 | 0.161290322581 | HEATR5B DENND1A REPS2 EPS15L1 REPS1 ITSN2 CLTC EPS15 CLTCL1 ITSN1 | endosomal transport |
| REAC:R-HSA-196025 | 0.00446905937216 | 0.0483870967742 | AP2M1 CLTC CLTCL1 | Formation of annular gap junctions |
| TF:M11442 | 0.00560722353442 | 0.370967741935 | AP1B1 CCDC32 AP2M1 AFTPH AP2S1 AP1AR SEC16A AP1S2 AP1G1 GAK MEA1 SYNRG AAK1 HEATR5B PIK3C2A NECAP2 BMP2K TNRC6A COMT PAAT SMAP2 AP1M1 EPN1 | Factor: Net; motif: NACCGGAAGTN |
| REAC:R-HSA-190873 | 0.00594072219467 | 0.0483870967742 | AP2M1 CLTC CLTCL1 | Gap junction degradation |
| CORUM:3231 | 0.00835252416677 | 0.0322580645161 | EPS15 STON2 | Eps15-stonin2 complex |
| GO:0099072 | 0.00909687797123 | 0.0806451612903 | AP2M1 AP2A1 AP2B1 AP2S1 AP2A2 | regulation of postsynaptic membrane neurotransmitter receptor levels |
| REAC:R-HSA-1643685 | 0.0107866384717 | 0.290322580645 | AP1B1 AP2A1 AP2B1 AP1S3 AP2A2 SP1 AP1G1 AP1S2 COMT AP2S1 HIP1 AP1S1 AP1M2 CLTC AP2M1 AP1M1 SEC24B EPS15 | Disease |
| HPA:0250000 | 0.0134276164035 | 0.661290322581 | AP1B1 AFTPH SYNRG STON2 HIP1 NUMB AMPH RALBP1 AP1S3 WNK1 SEC16A AP2A2 EPS15L1 GAK SYNJ1 CLTC FCHO2 AAK1 AP1S1 HEATR5B RUNDC3A NECAP2 BMP2K AAGAB REPS1 TNRC6A AP2A1 ITSN1 SEC24B SMAP2 DNAJC6 CLINT1 AP1G2 AP1AR SP1 COMT PAAT AP2B1 AP1G1 GULP1 EPS15 | hippocampus |
| HPA:0270362 | 0.0164967356246 | 0.596774193548 | AP1B1 AFTPH SYNRG STON2 HIP1 NUMB RALBP1 AP1S3 WNK1 BMP2K AP2A2 AP1G1 GAK ITSN2 MEA1 FCHO2 AP1S1 CLTC HEATR5B NECAP2 AAGAB REPS1 TNRC6A ZNF106 ITSN1 SEC24B AP1S2 PAAT CLINT1 AP1AR SP1 AP1G2 AP2B1 EPS15L1 GULP1 EPN1 EPS15 | kidney; cells in tubules[>=Medium] |
| HPA:0550052 | 0.0169001577899 | 0.629032258065 | AFTPH SYNRG STON2 HIP1 NUMB RALBP1 AP1S3 SEC16A AP2A2 EPS15L1 GAK SYNJ1 ITSN2 CLTC FCHO2 AP1S1 GKN1 HEATR5B BMP2K AAGAB REPS1 TNRC6A ZNF106 AP2A1 AP1S2 ITSN1 SEC24B SMAP2 PAAT CLINT1 AP1G2 AP1AR SP1 COMT AP2B1 AP1G1 GULP1 EPN1 EPS15 | stomach 2; glandular cells[>=Medium] |
| TF:M03987 | 0.0184984887283 | 0.290322580645 | AP1B1 PIK3C2A CCDC32 SMAP2 BMP2K AP2M1 GAK AP2S1 TNRC6A AP1AR SEC16A PAAT MEA1 AAK1 AP1M1 HEATR5B EPN1 NECAP2 | Factor: FEV; motif: ACCGGAAGTN |
| HPA:0091063 | 0.0210279097491 | 0.0806451612903 | AMPH DNAJC6 SYNJ1 AP2A2 AAK1 | cerebellum; synaptic glomeruli - core[High] |
| TF:M02061 | 0.0237715623184 | 0.403225806452 | AP1B1 CCDC32 AP2M1 AP2S1 AP1AR AP1S3 BMP2K AP1S2 AP1G1 GAK MEA1 AAK1 HEATR5B PIK3C2A NECAP2 SEC16A TNRC6A SYNJ1 SMAP2 PAAT CLINT1 NUMB COMT AP1M1 EPN1 | Factor: ERF; motif: ACCGGAARYN |
| HPA:0270361 | 0.0252350533702 | 0.661290322581 | AP1B1 AFTPH SYNRG STON2 HIP1 NUMB RALBP1 AP1S3 WNK1 BMP2K AP2A2 AP1G1 GAK SYNJ1 ITSN2 MEA1 FCHO2 AAK1 AP1S1 CLTC HEATR5B NECAP2 AAGAB REPS1 TNRC6A ZNF106 AP2A1 CLTCL1 ITSN1 SEC24B AP1S2 PAAT CLINT1 AP1AR SP1 AP1G2 AP2B1 EPS15L1 GULP1 EPN1 EPS15 | kidney; cells in tubules[>=Low] |
| HPA:0270000 | 0.0297721174649 | 0.725806451613 | AP1B1 AFTPH SYNRG STON2 HIP1 NUMB AMPH RALBP1 AP1S3 WNK1 SEC16A AP2A2 AP1G1 GAK SYNJ1 ITSN2 MEA1 FCHO2 AAK1 AP1S1 CLTC HEATR5B NECAP2 BMP2K AAGAB REPS1 TNRC6A ZNF106 AP2A1 CLTCL1 ITSN1 SEC24B AP1S2 DNAJC6 CLINT1 AP1G2 AP1AR SP1 COMT PAAT AP2B1 EPS15L1 GULP1 EPN1 EPS15 | kidney |
| TF:M03972 | 0.0302266482353 | 0.274193548387 | AP1B1 PIK3C2A CCDC32 SMAP2 SEC16A AP2M1 GAK AP2S1 TNRC6A AP1AR BMP2K PAAT MEA1 AAK1 AP1M1 EPN1 NECAP2 | Factor: ELK3; motif: ACCGGAAGTN |
| REAC:R-HSA-9006934 | 0.0305828429745 | 0.145161290323 | AP2A1 AP2B1 AP2A2 AP2M1 AP2S1 CLTC EPS15L1 EPN1 EPS15 | Signaling by Receptor Tyrosine Kinases |
| HPA:0550000 | 0.0313403006852 | 0.693548387097 | AP1B1 AFTPH SYNRG STON2 HIP1 NUMB RALBP1 AP1S3 WNK1 SEC16A AP2A2 AP1G1 GAK SYNJ1 ITSN2 GKN1 FCHO2 AP1S1 MEA1 HEATR5B CLTC NECAP2 BMP2K AAGAB REPS1 TNRC6A ZNF106 AP2A1 AP1S2 ITSN1 SEC24B SMAP2 PAAT CLINT1 AP1G2 AP1AR SP1 COMT AP2B1 EPS15L1 GULP1 EPN1 EPS15 | stomach 2 |
| HPA:0550051 | 0.0313403006852 | 0.693548387097 | AP1B1 AFTPH SYNRG STON2 HIP1 NUMB RALBP1 AP1S3 WNK1 SEC16A AP2A2 AP1G1 GAK SYNJ1 ITSN2 GKN1 FCHO2 AP1S1 MEA1 HEATR5B CLTC NECAP2 BMP2K AAGAB REPS1 TNRC6A ZNF106 AP2A1 AP1S2 ITSN1 SEC24B SMAP2 PAAT CLINT1 AP1G2 AP1AR SP1 COMT AP2B1 EPS15L1 GULP1 EPN1 EPS15 | stomach 2; glandular cells[>=Low] |
| HPA:0250131 | 0.0316163228729 | 0.612903225806 | AP1B1 AFTPH SYNRG STON2 HIP1 AP1G1 NUMB AMPH RALBP1 AP1S3 SEC16A AP2A2 EPS15 GAK SYNJ1 CLTC AAK1 AP1S1 HEATR5B RUNDC3A NECAP2 BMP2K AAGAB REPS1 TNRC6A AP2A1 ITSN1 SEC24B SMAP2 DNAJC6 CLINT1 AP1G2 AP1AR SP1 COMT PAAT AP2B1 EPS15L1 | hippocampus; neuronal cells[>=Low] |
| GO:0000323 | 0.0320525146839 | 0.209677419355 | AP1B1 AP2A1 AP1S3 AP2A2 AP2M1 AP2S1 AP1M2 AP1S2 CLTC AP1G1 AP1M1 AP1S1 AP2B1 | lytic vacuole |
| GO:0005764 | 0.0320525146839 | 0.209677419355 | AP1B1 AP2A1 AP1S3 AP2A2 AP2M1 AP2S1 AP1M2 AP1S2 CLTC AP1G1 AP1M1 AP1S1 AP2B1 | lysosome |
| WP:WP4829 | 0.0338231943576 | 0.0483870967742 | AP2A1 AP2A2 AP2B1 | mBDNF and proBDNF regulation of GABA neurotransmission |
| GO:0005737 | 0.0341489498205 | 0.887096774194 | AP1B1 AFTPH AP2M1 STON2 AP2S1 NUMB AMPH ZNF106 AP1S3 RALBP1 WNK1 SEC16A AP2A2 NECAP1 FCHO2 AP1G1 HIP1 SYNJ1 SYNRG ITSN2 CLTC STAMBP KIF13A HEATR5B AP1S1 GKN1 PIK3C2A NECAP2 BMP2K AAGAB REPS1 TNRC6A REPS2 AP1M2 AP2A1 DENND1A AAK1 AP1S2 ITSN1 SEC24B SMAP2 DNAJC6 CLINT1 AP1G2 AP1AR STAMBPL1 GAK COMT CLTCL1 PAAT AP2B1 EPS15L1 AP1M1 EPN1 EPS15 | cytoplasm |
| TF:M09613 | 0.0344738363059 | 0.564516129032 | AP1B1 AFTPH STAMBP AP2S1 NUMB RALBP1 SEC16A CCDC32 RSKR FCHO2 EPS15 GAK SYNRG ITSN2 MEA1 AP2M1 AAK1 CLTC PIK3C2A RUNDC3A NECAP2 BMP2K AAGAB TNRC6A ZNF106 CLTCL1 AP1S2 PAAT SMAP2 AP1AR SP1 COMT AP1G1 AP1M1 EPN1 | Factor: Fli-1; motif: RCMGGAAGYGNNN |
| HPA:0020051 | 0.0440469800091 | 0.677419354839 | AP1B1 AFTPH SYNRG STON2 HIP1 NUMB RALBP1 AP1S3 WNK1 SEC16A AP2A2 EPS15L1 GAK SYNJ1 MEA1 FCHO2 CLTCL1 AP1S1 CLTC HEATR5B NECAP2 BMP2K AAGAB REPS1 TNRC6A ZNF106 AP2A1 AP1S2 ITSN1 SEC24B SMAP2 PAAT CLINT1 AP1G2 AP1AR SP1 COMT AP2B1 AP1G1 GULP1 EPN1 EPS15 | adrenal gland; glandular cells[>=Low] |
| HPA:0020000 | 0.0447815621168 | 0.677419354839 | AP1B1 AFTPH SYNRG STON2 HIP1 NUMB RALBP1 AP1S3 WNK1 SEC16A AP2A2 EPS15L1 GAK SYNJ1 MEA1 FCHO2 CLTCL1 AP1S1 CLTC HEATR5B NECAP2 BMP2K AAGAB REPS1 TNRC6A ZNF106 AP2A1 AP1S2 ITSN1 SEC24B SMAP2 PAAT CLINT1 AP1G2 AP1AR SP1 COMT AP2B1 AP1G1 GULP1 EPN1 EPS15 | adrenal gland |
| TF:M11432 | 0.048481360773 | 0.629032258065 | AP1B1 AFTPH AP2M1 AP2S1 NUMB AMPH RALBP1 SEC16A CCDC32 AP2A2 EPS15 GAK ITSN2 MEA1 SYNRG AAK1 HEATR5B PIK3C2A RUNDC3A NECAP2 BMP2K AAGAB TNRC6A REPS2 AP2A1 CLTCL1 AP1S2 SYNJ1 SMAP2 DNAJC6 CLINT1 AP1AR SP1 COMT DENND1A PAAT AP1G1 AP1M1 EPN1 | Factor: Elk-1; motif: NACMGGAAGTN |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| AP2A2 | AP2M1 | 1.0 | 0.418 |
mixed_interface
|
| RALBP1 | REPS1 | 1.0 | 0.374 |
structurally_consistent (dimer)
|
| AP2S1 | AP2A1 | 1.0 | 0.71 |
structurally_consistent (dimer)
|
| AP2B1 | AP2A1 | 1.0 | 0.93 |
structurally_consistent (dimer)
|
| AP2M1 | EPS15 | 1.0 | 0.25 | |
| AP1B1 | AP1S2 | 1.0 | 0.24 |
mutually_exclusive (O43747)
|
| AP2B1 | AP1S2 | 1.0 | 0.142 | |
| AP1M1 | AP1B1 | 1.0 | 0.434 |
structurally_consistent (dimer)
|
| AP2A2 | AP2B1 | 1.0 | 0.336153846154 | |
| AP2S1 | AP2M1 | 1.0 | 0.706 |
mixed_interface
|
| AP2S1 | AAK1 | 1.0 | 0.132 | |
| AP1S2 | AP1G2 | 1.0 | 0.104 |
structurally_consistent (dimer)
|
| AP1B1 | AP1G1 | 1.0 | 0.682 |
mixed_interface
|
| RALBP1 | REPS2 | 1.0 | 0.28 |
structurally_consistent (dimer)
|
| AP2B1 | AP2S1 | 1.0 | 0.7 |
structurally_consistent (O95782)
|
| NECAP2 | AP2M1 | 1.0 | 0.1 |
structurally_consistent (dimer)
|
| AP2A2 | AP2S1 | 1.0 | 0.282 |
structurally_consistent (dimer)
|
| ITSN1 | AP2M1 | 1.0 | ||
| CCDC32 | AP2S1 | 1.0 | 0.13 |
structurally_consistent (dimer)
|
| AP1M2 | AP1G1 | 1.0 | 0.068 |
mixed_interface
|
| AP2M1 | AAK1 | 1.0 | 0.224 | |
| AP1M1 | AP1S2 | 1.0 | 0.28 |
mutually_exclusive (O43747)
structurally_consistent (dimer) |
| AP1S2 | AP1G1 | 1.0 | 0.226 |
structurally_consistent (dimer)
|
| AP1M1 | AP1G1 | 1.0 | 0.538 |
structurally_consistent (Q10567)
structurally_consistent (dimer) |
| AP2S1 | EPS15 | 1.0 | 0.104 |
structurally_consistent (dimer)
|
| AP2B1 | EPS15 | 1.0 | 0.186 | |
| AP2B1 | AP2M1 | 1.0 | 0.826 |
structurally_consistent (dimer)
|
| AP2B1 | NECAP2 | 1.0 | 0.09 |
mutually_exclusive (Q96CW1)
|
| AP1S2 | HEATR5B | 1.0 | 0.114 | |
| AP2S1 | AP1B1 | 1.0 | 0.258 | |
| NECAP2 | AP2A1 | 1.0 | 0.184 | |
| EPS15L1 | AP2M1 | 1.0 | 0.186 | |
| AP2M1 | AP1B1 | 1.0 | 0.384 |
structurally_consistent (dimer)
|
| AP1B1 | AP1M2 | 1.0 | 0.218 |
structurally_consistent (Q9BXS5)
structurally_consistent (dimer) |
| NECAP2 | AP1B1 | 0.999 | 0.14 |
mutually_exclusive (Q96CW1)
|
| EPS15L1 | EPS15 | 0.999 | 0.182 |
mutually_exclusive (Q59EK9)
|
| AP2B1 | AP1B1 | 0.999 | 0.718 |
mutually_exclusive (Q9Y6Q5)
|
| REPS1 | AAK1 | 0.999 | 0.036 | |
| RUNDC3A | RUNDC3B | 0.999 | ||
| EPS15L1 | AP2S1 | 0.999 | 0.222 | |
| EPS15L1 | AP2A1 | 0.999 | 0.32 | |
| PIK3C2A | STAMBPL1 | 0.999 | 0.0870769230769 | |
| AP1G2 | AP1M2 | 0.999 | 0.072 |
structurally_consistent (dimer)
|
| AP2A2 | NECAP2 | 0.999 | 0.138416666667 | |
| AP1B1 | AP2A1 | 0.999 | 0.49 | |
| ITSN1 | AP2S1 | 0.999 | ||
| CCDC32 | AAGAB | 0.999 | 0.11 |
mutually_exclusive (P53680)
|
| AP2B1 | ITSN1 | 0.999 | ||
| STAMBPL1 | CLINT1 | 0.999 | 0.134 | |
| AP1S2 | AP1AR | 0.999 | 0.052 | |
| AP1S2 | AFTPH | 0.999 | 0.072 | |
| STAMBP | CLINT1 | 0.999 | 0.162 |
structurally_consistent (dimer)
|
| AP2B1 | AP1M2 | 0.999 | 0.026 |
structurally_consistent (dimer)
|
| NECAP2 | AP2S1 | 0.999 | 0.076 |
structurally_consistent (dimer)
|
| AP2M1 | AP2A1 | 0.999 | 0.956 |
mutually_exclusive (P53680)
|
| AP2A2 | AAGAB | 0.999 | 0.1305 | |
| EPS15L1 | FCHO2 | 0.999 | 0.138 | |
| AP2B1 | STON2 | 0.999 | 0.134 | |
| AP1S1 | AP1M2 | 0.999 | 0.072 |
mutually_exclusive (O43747)
structurally_consistent (dimer) |
| AP1B1 | AP1S3 | 0.999 | 0.174 | |
| AP2A2 | EPS15L1 | 0.999 | 0.313555555556 | |
| AP2B1 | EPS15L1 | 0.999 | 0.446 | |
| AP1S2 | SYNRG | 0.999 | 0.152 | |
| EPS15 | AP2A1 | 0.999 | 0.186 | |
| AP2S1 | FCHO2 | 0.999 | 0.074 |
structurally_consistent (dimer)
|
| AP2B1 | FCHO2 | 0.999 | 0.114 | |
| AP1B1 | MEA1 | 0.999 | 0.084 | |
| SYNRG | AFTPH | 0.999 | 0.126 | |
| HEATR5B | AP1S3 | 0.999 | 0.032 | |
| BMP2K | AP2A1 | 0.999 | 0.184 | |
| AP2S1 | BMP2K | 0.999 | 0.186 | |
| AP1S3 | AP1G1 | 0.999 | 0.188 |
structurally_consistent (dimer)
|
| AP1S2 | AP1M2 | 0.999 | 0.174 |
mutually_exclusive (O75843)
|
| AP1M2 | AP1S3 | 0.999 | 0.024 | |
| AP2S1 | REPS1 | 0.999 | 0.044 | |
| FCHO2 | EPS15 | 0.998 | 0.142545454545 | |
| AAGAB | AP1S2 | 0.998 | 0.072 |
mutually_exclusive (O75843)
|
| AAGAB | AP2S1 | 0.998 | 0.058 |
structurally_consistent (dimer)
|
| PIK3C2A | CLINT1 | 0.998 | 0.068 | |
| AP2A2 | AP1B1 | 0.998 | 0.266 |
mutually_exclusive (O43747)
|
| AP1M1 | AP1S3 | 0.998 | 0.082 |
mutually_exclusive (O43747)
|
| AP2B1 | AP1M1 | 0.998 | 0.39 |
structurally_consistent (dimer)
|
| EPS15L1 | ITSN1 | 0.998 | ||
| AP2M1 | AP1G1 | 0.998 | 0.302 |
mutually_exclusive (P53680)
|
| REPS1 | EPS15 | 0.998 | 0.07 | |
| AP2A1 | AAK1 | 0.998 | 0.158 | |
| FCHO2 | AP2A1 | 0.998 | 0.188275862069 | |
| AFTPH | AP1S3 | 0.998 | 0.064 | |
| AP1M2 | MEA1 | 0.998 | 0.068 |
mutually_exclusive (Q9BXS5)
structurally_consistent (dimer) |
| BMP2K | AAK1 | 0.998 | 0.47 | |
| STAMBPL1 | GAK | 0.998 | 0.056 | |
| BMP2K | CLTC | 0.998 | 0.233142857143 | |
| AP2S1 | STON2 | 0.998 | 0.09 | |
| REPS2 | REPS1 | 0.998 | 0.144 |
mutually_exclusive (Q15311)
|
| AP2A2 | CCDC32 | 0.998 | 0.13 | |
| RALBP1 | AP2A1 | 0.998 | 0.14 | |
| AP2B1 | AP1G1 | 0.998 | 0.532 |
mutually_exclusive (Q9Y6Q5)
|
| AP2B1 | AAK1 | 0.998 | 0.198 | |
| AP2B1 | MEA1 | 0.998 | 0.086 | |
| AAGAB | AP2A1 | 0.998 | 0.1085 | |
| REPS1 | STON2 | 0.998 | 0.092 | |
| KIF13A | AP1S3 | 0.997 | ||
| AP1M1 | MEA1 | 0.997 | 0.084 |
mutually_exclusive (Q9Y6Q5)
structurally_consistent (dimer) |
| AP2B1 | BMP2K | 0.997 | 0.142 | |
| AP2M1 | BMP2K | 0.997 | 0.168 | |
| AP2B1 | AP1S3 | 0.997 | 0.16 | |
| AP2M1 | MEA1 | 0.997 | 0.124 |
structurally_consistent (dimer)
|
| AP2M1 | RALBP1 | 0.997 | 0.116 |
structurally_consistent (dimer)
|
| AP2B1 | REPS1 | 0.997 | 0.152 | |
| SYNRG | AP1S3 | 0.997 | 0.078 | |
| AP2M1 | REPS1 | 0.997 | 0.13 | |
| FCHO2 | STON2 | 0.997 | 0.066 | |
| AP1B1 | EPS15 | 0.997 | 0.198 | |
| AP2A1 | STON2 | 0.997 | 0.162 | |
| BMP2K | REPS1 | 0.997 | 0.068 | |
| ITSN2 | EPS15L1 | 0.997 | 0.118 | |
| REPS1 | STAMBP | 0.997 | 0.05 | |
| EPS15L1 | AP1B1 | 0.997 | 0.38 | |
| PIK3C2A | BMP2K | 0.997 | 0.156 | |
| CLINT1 | GAK | 0.996 | 0.098 |
mutually_exclusive (O95630)
|
| BMP2K | EPS15 | 0.996 | 0.044 | |
| ITSN1 | AP1B1 | 0.996 | ||
| STAMBPL1 | CLTC | 0.996 | 0.166 | |
| EPS15 | AAK1 | 0.996 | 0.052 | |
| AAGAB | AP1S3 | 0.996 | 0.046 |
mutually_exclusive (O75843)
|
| STAMBPL1 | SEC16A | 0.996 | ||
| AP1B1 | AP1G2 | 0.996 | 0.052 |
mutually_exclusive (Q9Y6Q5)
|
| ITSN2 | AP2M1 | 0.996 | 0.166 | |
| REPS1 | AP2A1 | 0.996 | 0.112 | |
| RUNDC3A | AAK1 | 0.996 | 0.09 | |
| CLINT1 | AAK1 | 0.996 | 0.11 | |
| RUNDC3A | EPS15 | 0.996 | 0.074 |
structurally_consistent (dimer)
|
| AP2M1 | DENND1A | 0.996 | 0.312 | |
| AP2A2 | EPS15 | 0.996 | 0.218 | |
| NECAP2 | NECAP1 | 0.996 | 0.076 | |
| BMP2K | STON2 | 0.995 | 0.058 | |
| EPS15 | STON2 | 0.995 | 0.11 | |
| AP2B1 | CLINT1 | 0.995 | 0.268 | |
| AP2M1 | AP1S3 | 0.995 | 0.098 | |
| AP2M1 | GULP1 | 0.995 | 0.122 | |
| HEATR5B | AFTPH | 0.995 | 0.326 | |
| EPS15L1 | RUNDC3A | 0.995 | 0.09 |
structurally_consistent (dimer)
|
| RALBP1 | AAK1 | 0.995 | 0.154 | |
| STAMBPL1 | EPS15 | 0.995 | 0.066 | |
| CLTCL1 | STAMBPL1 | 0.994 | 0.141 |
structurally_consistent (dimer)
|
| FCHO2 | AP1B1 | 0.994 | 0.208 | |
| ZNF106 | STON2 | 0.994 | 0.1 | |
| ZNF106 | STAMBPL1 | 0.994 | 0.106 | |
| PIK3C2A | CLTC | 0.994 | 0.398 | |
| AP2A2 | AP2A1 | 0.994 | 0.3585 | |
| CCDC32 | AP2A1 | 0.994 | 0.132 | |
| PIK3C2A | CLTCL1 | 0.994 | 0.136 | |
| AP1AR | AP1S3 | 0.994 | 0.096 | |
| HEATR5B | AP1G1 | 0.994 | 0.048 | |
| AP2M1 | STON2 | 0.994 | 0.138 | |
| AP2S1 | RALBP1 | 0.993 | 0.204 | |
| AP1B1 | HEATR5B | 0.993 | 0.224 | |
| NUMB | GAK | 0.993 | 0.082 | |
| AP2A2 | RUNDC3A | 0.993 | 0.142 | |
| CLTCL1 | STAMBP | 0.993 | 0.126 | |
| EPN1 | NUMB | 0.993 | 0.048 | |
| AP1G2 | AP1G1 | 0.993 | 0.096 |
mutually_exclusive (Q9Y6Q5)
structurally_consistent (dimer) |
| AP1S2 | CLINT1 | 0.993 | 0.076 | |
| FCHO2 | BMP2K | 0.993 | 0.11 | |
| CLINT1 | AP2A1 | 0.992 | 0.224 | |
| AP2M1 | RUNDC3A | 0.992 | 0.086 | |
| RALBP1 | BMP2K | 0.992 | 0.104 | |
| AP2B1 | AP1G2 | 0.992 | 0.084 |
mutually_exclusive (Q9Y6Q5)
|
| BMP2K | STAMBPL1 | 0.992 | 0.126 | |
| AP2M1 | AP1S1 | 0.992 | 0.078 | |
| AP1S2 | MEA1 | 0.992 | 0.038 | |
| AP1G2 | AP1S3 | 0.991 | 0.046 |
structurally_consistent (dimer)
|
| BMP2K | CLINT1 | 0.991 | 0.072 | |
| SYNJ1 | PAAT | 0.991 | 0.142 | |
| STAMBP | CLTC | 0.991 | 0.334 | |
| RALBP1 | RUNDC3A | 0.991 | 0.078 | |
| SYNRG | HEATR5B | 0.991 | 0.125 | |
| DENND1A | HIP1 | 0.991 | 0.104 | |
| STON2 | GAK | 0.991 | 0.11 | |
| PAAT | STAMBP | 0.99 | 0.094 | |
| HEATR5B | AP1G2 | 0.99 | 0.064 | |
| RUNDC3A | AP2A1 | 0.99 | 0.13 | |
| CLTCL1 | NUMB | 0.99 | 0.158 | |
| WNK1 | NUMB | 0.99 | 0.068 | |
| AP2M1 | NECAP1 | 0.99 | 0.158 |
structurally_consistent (dimer)
|
| REPS1 | CLINT1 | 0.99 | 0.156 | |
| EPN1 | STAMBP | 0.99 | 0.066 | |
| AAGAB | AP2M1 | 0.99 | 0.086 |
mutually_exclusive (P53680)
|
| AP1S2 | AP1S3 | 0.99 | 0.062 | |
| CLTCL1 | CLINT1 | 0.989 | 0.088 | |
| AP2M1 | AP1S2 | 0.989 | 0.192 | |
| AP2B1 | NECAP1 | 0.989 | 0.108 | |
| STON2 | NUMB | 0.989 | 0.14 | |
| WNK1 | STAMBPL1 | 0.989 | 0.04 | |
| AFTPH | AP1G1 | 0.989 | 0.09 | |
| AP2B1 | AP1S1 | 0.989 | 0.186 | |
| CCDC32 | AP2M1 | 0.989 | 0.104 |
mutually_exclusive (P53680)
|
| REPS1 | STAMBPL1 | 0.989 | 0.064 | |
| STAMBPL1 | NUMB | 0.988 | 0.101333333333 | |
| AP1S1 | AAK1 | 0.988 | 0.036 | |
| NECAP1 | REPS1 | 0.988 | 0.09 | |
| SMAP2 | NUMB | 0.988 | 0.032085106383 | |
| BMP2K | WNK1 | 0.988 | 0.17 | |
| AAGAB | AP1G1 | 0.988 | 0.082 | |
| AP1S1 | SYNJ1 | 0.987 | 0.072 | |
| ZNF106 | CLTCL1 | 0.987 | 0.092 | |
| SMAP2 | CLINT1 | 0.987 | 0.046 | |
| GAK | CLTC | 0.987 | 0.294 | |
| FCHO2 | AP2M1 | 0.987 | 0.104 |
structurally_consistent (dimer)
|
| AP1M1 | AP1G2 | 0.987 | 0.016 |
mutually_exclusive (P56377)
|
| PAAT | CLTC | 0.986 | 0.178325 | |
| PAAT | REPS1 | 0.986 | 0.08 | |
| RALBP1 | EPS15 | 0.986 | 0.09 | |
| KIF13A | AP1M2 | 0.986 | ||
| DENND1A | NUMB | 0.986 | 0.156 | |
| EPN1 | AAK1 | 0.986 | 0.1 | |
| AP1M1 | AFTPH | 0.986 | 0.154 | |
| BMP2K | HIP1 | 0.986 | 0.066 | |
| AP1S1 | AP1B1 | 0.985 | 0.112 |
mutually_exclusive (O43747)
|
| FCHO2 | NECAP1 | 0.985 | 0.102 | |
| AP1M1 | SYNRG | 0.985 | 0.182 | |
| EPS15L1 | RALBP1 | 0.985 | 0.126 | |
| BMP2K | SEC16A | 0.985 | ||
| AP2B1 | RALBP1 | 0.985 | 0.124 |
mutually_exclusive (Q96CW1)
|
| ITSN2 | ITSN1 | 0.985 | ||
| SYNRG | AP1G1 | 0.985 | 0.23 | |
| NECAP1 | NUMB | 0.984 | 0.116 | |
| BMP2K | STAMBP | 0.984 | 0.058 | |
| AP1B1 | NECAP1 | 0.984 | 0.278 |
structurally_consistent (dimer)
|
| AP1B1 | AFTPH | 0.984 | 0.184 | |
| MEA1 | AP1G1 | 0.984 | 0.076 | |
| STAMBPL1 | STAMBP | 0.984 | 0.03 | |
| PIK3C2A | ZNF106 | 0.983 | 0.128 | |
| SMAP2 | STAMBPL1 | 0.983 | 0.04 | |
| WNK1 | STON2 | 0.983 | 0.072 | |
| AP2M1 | NUMB | 0.983 | 0.096 | |
| AP1B1 | RALBP1 | 0.983 | 0.16 |
mutually_exclusive (Q96CW1)
|
| DENND1A | STAMBPL1 | 0.982 | 0.118 | |
| ITSN2 | AP2S1 | 0.982 | 0.084 | |
| BMP2K | ZNF106 | 0.982 | 0.052 | |
| AP2A2 | STON2 | 0.982 | 0.166 | |
| ZNF106 | SEC16A | 0.982 | ||
| NECAP1 | BMP2K | 0.982 | 0.134 | |
| FCHO2 | AP1S1 | 0.982 | 0.068 | |
| PIK3C2A | DENND1A | 0.981 | 0.12 | |
| AP2B1 | RUNDC3A | 0.981 | 0.152 | |
| ZNF106 | GAK | 0.981 | 0.096 | |
| HIP1 | AP2A1 | 0.981 | 0.152 | |
| FCHO2 | NUMB | 0.981 | 0.206 | |
| ZNF106 | WNK1 | 0.981 | 0.05 | |
| AP2B1 | AAGAB | 0.981 | 0.13 | |
| RALBP1 | STON2 | 0.98 | 0.138 | |
| WNK1 | GAK | 0.98 | 0.114 | |
| STAMBPL1 | STON2 | 0.98 | 0.106 | |
| PIK3C2A | SEC16A | 0.98 | ||
| FCHO2 | AAK1 | 0.98 | 0.028 | |
| AP1S1 | AP1M1 | 0.98 | 0.248 | |
| AAK1 | GAK | 0.979 | 0.166 | |
| AP1G2 | AFTPH | 0.979 | 0.06 | |
| PIK3C2A | GAK | 0.979 | 0.14 | |
| DENND1A | AAK1 | 0.979 | 0.086 | |
| AP2M1 | CLINT1 | 0.979 | 0.148 | |
| AP2A2 | RALBP1 | 0.978 | 0.168 | |
| CLTCL1 | CLTC | 0.978 | 0.534 | |
| HIP1 | AAK1 | 0.978 | 0.026 | |
| AP1S1 | AP1S3 | 0.978 | 0.2 | |
| MEA1 | AP1S3 | 0.978 | 0.07 | |
| DENND1A | CLTCL1 | 0.977 | 0.126 | |
| NECAP1 | CLINT1 | 0.977 | 0.136 | |
| AP2A2 | ITSN1 | 0.976 | ||
| DENND1A | BMP2K | 0.976 | 0.12 | |
| WNK1 | STAMBP | 0.976 | 0.084 | |
| STAMBPL1 | AAK1 | 0.976 | 0.056 | |
| AP2M1 | PIK3C2A | 0.976 | 0.175 | |
| AP2M1 | SYNJ1 | 0.976 | 0.155166666667 | |
| PAAT | STAMBPL1 | 0.976 | 0.084 |
structurally_consistent (dimer)
|
| CLINT1 | CLTC | 0.976 | 0.295 | |
| NECAP1 | AAK1 | 0.976 | 0.09 | |
| EPN1 | BMP2K | 0.975 | 0.266 | |
| ITSN2 | AP2A1 | 0.975 | 0.18 | |
| ITSN1 | RALBP1 | 0.975 | ||
| AP1S1 | MEA1 | 0.975 | 0.03 | |
| REPS2 | AAK1 | 0.975 | 0.0945 | |
| NECAP1 | AP1G1 | 0.974 | 0.126 |
mutually_exclusive (P53680)
|
| REPS1 | AP1G1 | 0.974 | 0.086 | |
| AP2S1 | AP1S3 | 0.974 | 0.098 |
mutually_exclusive (O43747)
|
| AP1B1 | STON2 | 0.974 | 0.174 | |
| STAMBPL1 | AP2A1 | 0.974 | 0.132 | |
| AP2B1 | CCDC32 | 0.974 | 0.06 | |
| TNRC6A | STAMBPL1 | 0.973 | 0.12 | |
| AAK1 | NUMB | 0.973 | 0.056 | |
| ITSN2 | AP1B1 | 0.973 | 0.126 | |
| DENND1A | STON2 | 0.973 | 0.106 | |
| SYNJ1 | NECAP1 | 0.972 | 0.202 | |
| EPN1 | REPS1 | 0.972 | 0.062 | |
| WNK1 | REPS1 | 0.972 | 0.104 | |
| AP1B1 | SYNRG | 0.972 | 0.179 | |
| AP1S1 | AP1G1 | 0.971 | 0.402666666667 |
structurally_consistent (dimer)
|
| AP2A2 | AP1S3 | 0.971 | 0.142 |
structurally_consistent (O43747)
|
| EPN1 | STON2 | 0.971 | 0.096 | |
| EPS15 | NUMB | 0.971 | 0.06 | |
| PIK3C2A | STAMBP | 0.97 | 0.064 | |
| RALBP1 | STAMBP | 0.97 | 0.12 | |
| BMP2K | NUMB | 0.97 | 0.136 | |
| NECAP1 | STON2 | 0.97 | 0.108 | |
| CLINT1 | EPS15 | 0.97 | 0.252 | |
| DNAJC6 | GULP1 | 0.97 | 0.082 | |
| EPS15L1 | STON2 | 0.97 | 0.122 | |
| DENND1A | GAK | 0.97 | 0.14 | |
| AP2S1 | RUNDC3A | 0.97 | 0.054 | |
| EPS15 | GAK | 0.969 | 0.082 | |
| EPN1 | NECAP1 | 0.969 | 0.16 | |
| AP1S1 | NECAP1 | 0.968 | 0.048 |
structurally_consistent (Q9Y6Q5)
|
| DENND1A | EPS15 | 0.968 | 0.108 | |
| HIP1 | STAMBPL1 | 0.968 | 0.062 | |
| AP2B1 | DENND1A | 0.967 | 0.280666666667 | |
| GULP1 | REPS1 | 0.967 | 0.084 | |
| ZNF106 | NUMB | 0.967 | 0.052 | |
| AP1S1 | AP1S2 | 0.966 | 0.056 |
mutually_exclusive (O43747)
|
| FCHO2 | SYNJ1 | 0.966 | 0.138 | |
| AP1M1 | NECAP1 | 0.966 | 0.22 |
structurally_consistent (dimer)
|
| SMAP2 | GAK | 0.966 | 0.118 | |
| PIK3C2A | NUMB | 0.966 | 0.09 | |
| DENND1A | AP2A1 | 0.965 | 0.12 | |
| EPN1 | STAMBPL1 | 0.965 | 0.082 | |
| NECAP1 | EPS15 | 0.965 | 0.146 | |
| CLTCL1 | GAK | 0.965 | 0.184 | |
| AP1B1 | REPS1 | 0.965 | 0.114 | |
| CLINT1 | STON2 | 0.964 | 0.1 | |
| EPN1 | WNK1 | 0.964 | 0.066 | |
| FCHO2 | REPS1 | 0.964 | 0.04 | |
| AP1S3 | AP2A1 | 0.964 | 0.132 | |
| AP2A2 | ITSN2 | 0.963 | 0.36 | |
| AP1S2 | AP2A1 | 0.963 | 0.104 | |
| WNK1 | HIP1 | 0.963 | 0.022 | |
| SYNJ1 | RALBP1 | 0.963 | 0.136 | |
| HIP1 | STAMBP | 0.962 | 0.048 | |
| RALBP1 | CLINT1 | 0.962 | 0.11 | |
| PIK3C2A | AP2A1 | 0.962 | 0.166 | |
| AP1B1 | SYNJ1 | 0.961 | 0.194 | |
| AP1S3 | STON2 | 0.961 | 0.09 | |
| CLTCL1 | SEC16A | 0.961 | ||
| AP2S1 | AP1S2 | 0.961 | 0.176 | |
| AP2B1 | STAMBPL1 | 0.961 | 0.08 | |
| ZNF106 | AP2A1 | 0.959 | 0.116 | |
| AP2A2 | FCHO2 | 0.959 | 0.146 | |
| ITSN1 | EPS15 | 0.959 | ||
| PAAT | HIP1 | 0.959 | 0.06 | |
| PIK3C2A | AAK1 | 0.959 | 0.074 | |
| SYNJ1 | AP1G1 | 0.958 | 0.094 | |
| AP1S1 | RALBP1 | 0.958 | 0.062 | |
| AP1S1 | REPS1 | 0.958 | 0.052 | |
| PAAT | AAK1 | 0.958 | 0.084 | |
| WNK1 | EPS15 | 0.958 | 0.1 | |
| AP2B1 | STAMBP | 0.958 | 0.242 | |
| ITSN1 | STON2 | 0.957 | ||
| ITSN2 | AP2B1 | 0.957 | 0.082 | |
| BMP2K | GAK | 0.957 | 0.106 | |
| DENND1A | SEC16A | 0.956 | ||
| EPN1 | PAAT | 0.956 | 0.106 | |
| AP2B1 | NUMB | 0.956 | 0.152 | |
| ITSN1 | AP2A1 | 0.955 | ||
| HIP1 | GAK | 0.955 | 0.058 | |
| AP2A2 | AP1S2 | 0.955 | 0.166 | |
| STON2 | AAK1 | 0.955 | 0.074 | |
| TNRC6A | BMP2K | 0.954 | 0.102 | |
| AP1B1 | CLINT1 | 0.954 | 0.276 | |
| WNK1 | AAK1 | 0.954 | 0.06 | |
| RALBP1 | AP1G1 | 0.953 | 0.118 | |
| AP2A2 | AAK1 | 0.953 | 0.258 | |
| EPS15L1 | AAK1 | 0.953 | 0.122 | |
| DNAJC6 | CLINT1 | 0.953 | 0.124 | |
| AP1B1 | BMP2K | 0.953 | 0.222 | |
| CLTCL1 | HIP1 | 0.953 | 0.18 | |
| HEATR5B | AP1M2 | 0.953 | 0.086 | |
| SYNJ1 | REPS1 | 0.953 | 0.188 | |
| CLTCL1 | AP2A1 | 0.952 | 0.252352941176 | |
| SEC24B | BMP2K | 0.952 | 0.086 | |
| STAMBP | AP2A1 | 0.952 | 0.102 | |
| BMP2K | CLTCL1 | 0.952 | 0.088 | |
| STAMBP | SEC16A | 0.951 | ||
| AP2B1 | GAK | 0.951 | 0.224 | |
| AFTPH | AP1M2 | 0.951 | 0.044 | |
| SYNRG | AP1M2 | 0.951 | ||
| AP1S3 | CLINT1 | 0.95 | 0.134 | |
| KIF13A | AP1G1 | 0.95 | ||
| AP2A1 | NUMB | 0.95 | 0.118 | |
| RUNDC3A | CLINT1 | 0.949 | 0.114 | |
| ITSN1 | MEA1 | 0.949 | ||
| AP1S1 | AP1G2 | 0.949 | 0.028 |
structurally_consistent (dimer)
|
| AAGAB | AP1S1 | 0.948 | 0.038 |
mutually_exclusive (O75843)
structurally_consistent (dimer) |
| ZNF106 | EPS15 | 0.947 | 0.114 | |
| SYNRG | AP1G2 | 0.947 | 0.222 | |
| FCHO2 | RALBP1 | 0.947 | 0.078 | |
| AP1G2 | MEA1 | 0.946 | 0.014 | |
| MEA1 | EPS15 | 0.946 | 0.046 | |
| ITSN1 | AP1S3 | 0.946 | ||
| PAAT | CLTCL1 | 0.946 | 0.098 | |
| AP2A2 | AMPH | 0.945 | 0.226607843137 | |
| HIP1 | NUMB | 0.945 | 0.058 | |
| AP1S1 | STON2 | 0.945 | 0.074 | |
| PIK3C2A | HIP1 | 0.944 | 0.084 | |
| EPN1 | DENND1A | 0.944 | 0.144 | |
| AP1M1 | HEATR5B | 0.943 | 0.14 | |
| DENND1A | REPS1 | 0.943 | 0.174 | |
| DENND1A | CLINT1 | 0.943 | 0.094 | |
| AP1B1 | AP1AR | 0.942 | 0.094 | |
| AP2S1 | SYNJ1 | 0.942 | 0.086 | |
| GKN1 | CLTCL1 | 0.941 | ||
| FCHO2 | DENND1A | 0.94 | 0.054 | |
| TNRC6A | PIK3C2A | 0.94 | 0.198 | |
| EPN1 | SMAP2 | 0.94 | 0.104 | |
| AP2B1 | AMPH | 0.94 | 0.144 | |
| EPS15 | CLTC | 0.94 | 0.378 | |
| PIK3C2A | REPS1 | 0.94 | 0.05 | |
| EPN1 | RALBP1 | 0.938 | 0.05 | |
| STAMBP | GAK | 0.938 | 0.104 |
structurally_consistent (dimer)
|
| SMAP2 | STAMBP | 0.937 | 0.032 | |
| EPN1 | GAK | 0.937 | 0.068 | |
| PIK3C2A | EPS15 | 0.937 | 0.026 | |
| SP1 | WNK1 | 0.936 | 0.072 | |
| STON2 | CLTC | 0.936 | 0.256325 | |
| RUNDC3A | REPS1 | 0.935 | 0.076 |
structurally_consistent (dimer)
|
| ITSN2 | EPS15 | 0.935 | 0.15 | |
| PAAT | AP2A1 | 0.934 | 0.186 | |
| AP1AR | SYNRG | 0.933 | 0.088 | |
| EPS15L1 | MEA1 | 0.933 | 0.138 | |
| BMP2K | RUNDC3A | 0.933 | 0.106 | |
| EPN1 | EPS15 | 0.933 | 0.022 | |
| MEA1 | STON2 | 0.933 | 0.064 | |
| ITSN2 | FCHO2 | 0.932 | 0.052 | |
| AP1S1 | COMT | 0.932 | 0.08 | |
| FCHO2 | AP1S3 | 0.932 | 0.072 | |
| TNRC6A | CLTC | 0.932 | 0.242095238095 | |
| AP2A2 | BMP2K | 0.931 | 0.146 | |
| SMAP2 | ZNF106 | 0.931 | 0.034 | |
| HIP1 | SEC16A | 0.93 | ||
| AMPH | AP2A1 | 0.93 | 0.164 | |
| NECAP2 | AAK1 | 0.929 | 0.052 | |
| AP1S1 | AP2A1 | 0.929 | 0.204 |
structurally_consistent (dimer)
|
| AP2A2 | AP1S1 | 0.929 | 0.158235294118 |
structurally_consistent (O43747)
structurally_consistent (dimer) |
| PAAT | PIK3C2A | 0.928 | 0.126 | |
| AP1S1 | NUMB | 0.928 | 0.03 | |
| AP2A2 | REPS1 | 0.928 | 0.288079365079 | |
| NECAP2 | EPS15L1 | 0.927 | 0.096 | |
| EPS15L1 | REPS1 | 0.927 | 0.112 |
mutually_exclusive (Q59EK9)
|
| AP2M1 | AMPH | 0.927 | 0.341 | |
| PAAT | GULP1 | 0.926 | 0.1 | |
| ITSN1 | BMP2K | 0.924 | ||
| AP2B1 | SYNJ1 | 0.924 | 0.198 | |
| NECAP1 | RALBP1 | 0.924 | 0.142 |
mutually_exclusive (Q96CW1)
|
| AP2S1 | CLINT1 | 0.923 | 0.282 | |
| ITSN1 | REPS1 | 0.922 | ||
| SYNJ1 | AAK1 | 0.922 | 0.14 | |
| FCHO2 | SEC16A | 0.92 | ||
| SEC24B | DENND1A | 0.919 | 0.106 | |
| EPN1 | HIP1 | 0.918 | 0.042 | |
| AP1AR | AFTPH | 0.918 | 0.086 | |
| AP1M1 | SYNJ1 | 0.917 | 0.162 | |
| AP1AR | AP1G1 | 0.916 | 0.112 |
structurally_consistent (Q9BXS5)
structurally_consistent (dimer) |
| TNRC6A | CLINT1 | 0.916 | 0.138 | |
| GAK | SEC16A | 0.915 | ||
| AP1B1 | HIP1 | 0.914 | 0.064 | |
| AP2A1 | GAK | 0.913 | 0.11 | |
| SEC24B | AP1G1 | 0.913 | 0.186 | |
| NECAP2 | ITSN1 | 0.913 | ||
| AP1M1 | AP1M2 | 0.912 | 0.056 |
structurally_consistent (dimer)
|
| PIK3C2A | DNAJC6 | 0.911 | 0.236 | |
| HIP1 | STON2 | 0.91 | 0.1 | |
| SEC24B | PIK3C2A | 0.91 | 0.122 | |
| AP2S1 | MEA1 | 0.91 | 0.044 | |
| SMAP2 | WNK1 | 0.909 | 0.028 | |
| PAAT | CLINT1 | 0.907 | 0.078 | |
| AAGAB | AP1B1 | 0.907 | 0.066 | |
| STAMBP | NUMB | 0.907 | 0.02 | |
| AP2B1 | CLTC | 0.907 | 0.73 | |
| PIK3C2A | WNK1 | 0.906 | 0.07 | |
| ITSN1 | AAK1 | 0.905 | ||
| FCHO2 | AP1G1 | 0.905 | 0.086 |
mutually_exclusive (P53680)
|
| AAK1 | CLTC | 0.905 | 0.232 | |
| AP1AR | HEATR5B | 0.905 | 0.05 | |
| AP2M1 | CLTC | 0.903 | 0.611 | |
| SEC24B | CLINT1 | 0.903 | 0.106 | |
| EPN1 | PIK3C2A | 0.903 | 0.068 | |
| AP2B1 | TNRC6A | 0.902 | 0.33 | |
| AP2B1 | PIK3C2A | 0.902 | 0.13 | |
| DENND1A | CLTC | 0.901 | 0.218 | |
| STAMBP | STON2 | 0.901 | 0.068 | |
| HIP1 | REPS1 | 0.901 | 0.046 | |
| AP1B1 | KIF13A | 0.899 | ||
| AP1M1 | RALBP1 | 0.898 | 0.132 | |
| NECAP1 | AP2A1 | 0.898 | 0.168 |
mutually_exclusive (P53680)
|
| FCHO2 | SEC24B | 0.897 | 0.114 | |
| EPN1 | FCHO2 | 0.897 | 0.04 | |
| AP1S1 | CLINT1 | 0.896 | 0.23 | |
| REPS1 | CLTC | 0.896 | 0.22 | |
| AP1S2 | STON2 | 0.896 | 0.15 | |
| NECAP2 | AP1G1 | 0.894 | 0.108666666667 | |
| DNAJC6 | CLTC | 0.894 | 0.442666666667 | |
| AP1M1 | AP1AR | 0.893 | 0.062 |
structurally_consistent (dimer)
|
| AP1B1 | NUMB | 0.893 | 0.066 | |
| AP1AR | AP1G2 | 0.893 | 0.06 |
structurally_consistent (O43747)
|
| TNRC6A | STON2 | 0.892 | 0.118 | |
| AP2M1 | KIF13A | 0.892 | ||
| SEC24B | SEC16A | 0.891 | ||
| AP1B1 | AAK1 | 0.89 | 0.176 | |
| NECAP1 | SYNRG | 0.889 | 0.104 | |
| NECAP1 | DENND1A | 0.888 | 0.106 | |
| EPN1 | SYNJ1 | 0.887 | 0.125666666667 | |
| AP2M1 | GKN1 | 0.887 | ||
| PIK3C2A | STON2 | 0.884 | 0.144 | |
| NECAP1 | WNK1 | 0.884 | 0.088 | |
| RALBP1 | PIK3C2A | 0.884 | 0.11 | |
| RALBP1 | SMAP2 | 0.881 | 0.068 | |
| AP1S1 | SEC24B | 0.881 | 0.084 |
structurally_consistent (dimer)
|
| AP1M1 | COMT | 0.881 | 0.156 |
structurally_consistent (dimer)
|
| DENND1A | WNK1 | 0.88 | 0.09 | |
| SEC24B | EPS15 | 0.879 | 0.122 | |
| AP1S1 | KIF13A | 0.879 | ||
| ITSN1 | AP1G1 | 0.878 | ||
| SEC24B | AAK1 | 0.878 | 0.156 | |
| BMP2K | DNAJC6 | 0.877 | 0.078 | |
| AP2S1 | AP1S1 | 0.876 | 0.1 | |
| SYNJ1 | STAMBPL1 | 0.874 | 0.134 | |
| SP1 | ZNF106 | 0.874 | 0.12 | |
| AP1S1 | SYNRG | 0.872 | 0.054 | |
| AP1M1 | SEC24B | 0.872 | 0.104 | |
| SYNJ1 | DENND1A | 0.87 | 0.12 | |
| RALBP1 | DNAJC6 | 0.869 | 0.132 | |
| AP2B1 | ZNF106 | 0.868 | 0.156 | |
| CLTCL1 | EPS15 | 0.868 | 0.096 | |
| RALBP1 | GULP1 | 0.867 | 0.064 | |
| TNRC6A | SEC16A | 0.866 | ||
| WNK1 | CLTC | 0.865 | 0.442 | |
| SP1 | AAK1 | 0.863 | 0.02 | |
| NECAP1 | SEC24B | 0.862 | 0.098 | |
| NUMB | CLTC | 0.862 | 0.37 | |
| ZNF106 | CLINT1 | 0.86 | 0.04 | |
| GKN1 | GULP1 | 0.859 | ||
| CLTCL1 | STON2 | 0.858 | 0.082495049505 | |
| AP1G1 | STON2 | 0.857 | 0.086 | |
| CLINT1 | NUMB | 0.857 | 0.138 | |
| WNK1 | AP2A1 | 0.857 | 0.096 | |
| PAAT | BMP2K | 0.855 | 0.118 | |
| PAAT | GKN1 | 0.855 | ||
| FCHO2 | MEA1 | 0.855 | 0.046 | |
| PAAT | NUMB | 0.854 | 0.094 | |
| GULP1 | NUMB | 0.852 | 0.082 | |
| SMAP2 | AAK1 | 0.848 | 0.024 | |
| NECAP2 | REPS1 | 0.847 | 0.04 | |
| NECAP2 | RALBP1 | 0.846 | 0.138 |
mutually_exclusive (Q96CW1)
|
| EPN1 | AP1G1 | 0.845 | 0.092 | |
| EPN1 | SEC24B | 0.845 | 0.132 | |
| CCDC32 | AP1B1 | 0.845 | 0.092 | |
| BMP2K | GULP1 | 0.844 | 0.09 | |
| SEC24B | CLTCL1 | 0.843 | 0.158 | |
| TNRC6A | DENND1A | 0.842 | 0.126 | |
| HIP1 | CLINT1 | 0.839 | 0.136 | |
| AP1B1 | AMPH | 0.839 | 0.192 | |
| SEC24B | SMAP2 | 0.839 | 0.052 | |
| AP1S2 | KIF13A | 0.839 | ||
| EPS15L1 | AP1G1 | 0.838 | 0.274 | |
| AP2B1 | WNK1 | 0.838 | 0.14 | |
| AP2M1 | TNRC6A | 0.836 | 0.246 | |
| SYNJ1 | STON2 | 0.836 | 0.16 | |
| AP1S2 | COMT | 0.832 | 0.092 |
structurally_consistent (Q9BXS5)
|
| TNRC6A | STAMBP | 0.832 | 0.134 | |
| ITSN1 | FCHO2 | 0.831 | ||
| WNK1 | CLTCL1 | 0.831 | 0.214 | |
| AP2A1 | SEC16A | 0.83 | ||
| AP1G1 | AP2A1 | 0.83 | 0.332 | |
| PAAT | GAK | 0.829 | 0.152 | |
| FCHO2 | AP1S2 | 0.826 | 0.054 | |
| FCHO2 | WNK1 | 0.825 | 0.048 | |
| AP2S1 | REPS2 | 0.824 | 0.12 |
structurally_consistent (dimer)
|
| SYNJ1 | AP2A1 | 0.823 | 0.264 | |
| AFTPH | MEA1 | 0.822 | 0.078 | |
| AP1M1 | REPS1 | 0.822 | 0.07 | |
| AP2A1 | CLTC | 0.822 | 0.73 | |
| PAAT | RALBP1 | 0.821 | 0.114 |
mutually_exclusive (Q96CW1)
|
| SEC24B | STON2 | 0.821 | 0.098 | |
| FCHO2 | CLTC | 0.819 | 0.192 | |
| NECAP1 | AP1M2 | 0.819 | 0.04 |
mutually_exclusive (Q9BXS5)
structurally_consistent (dimer) |
| SYNJ1 | BMP2K | 0.817 | 0.156 | |
| AP2S1 | PAAT | 0.817 | 0.104 | |
| AP2A2 | CLINT1 | 0.817 | 0.106 | |
| SYNJ1 | SYNRG | 0.814 | 0.094 | |
| HIP1 | EPS15 | 0.811 | 0.054 | |
| RALBP1 | MEA1 | 0.81 | 0.014 |
mutually_exclusive (Q96CW1)
|
| HIP1 | CLTC | 0.81 | 0.298 | |
| NECAP2 | EPS15 | 0.81 | 0.17 | |
| DENND1A | STAMBP | 0.808 | 0.07 | |
| SYNJ1 | NUMB | 0.808 | 0.196 | |
| SYNJ1 | STAMBP | 0.807 | 0.148 | |
| PAAT | DNAJC6 | 0.806 | 0.074 | |
| NECAP1 | AP1S3 | 0.806 | 0.072 | |
| RUNDC3B | AAK1 | 0.805 | ||
| SMAP2 | BMP2K | 0.798 | 0.048 | |
| AP1M1 | KIF13A | 0.797 | ||
| DNAJC6 | GAK | 0.796 | 0.178 | |
| AP1G1 | AAK1 | 0.796 | 0.092 | |
| ITSN1 | AP1S2 | 0.796 | ||
| NECAP2 | BMP2K | 0.796 | 0.142 | |
| REPS1 | SEC16A | 0.795 | ||
| SYNJ1 | AP1S3 | 0.795 | 0.08 | |
| KIF13A | AFTPH | 0.795 | ||
| SYNRG | KIF13A | 0.795 | ||
| KIF13A | HEATR5B | 0.795 | ||
| PAAT | AP1AR | 0.795 | 0.086 | |
| AP2M1 | STAMBPL1 | 0.794 | 0.098 | |
| AP2B1 | HIP1 | 0.794 | 0.132 | |
| ZNF106 | CLTC | 0.794 | 0.204095238095 | |
| AP1G2 | CLINT1 | 0.794 | 0.046 | |
| AP2M1 | SEC24B | 0.793 | 0.254 | |
| SEC24B | AP2A1 | 0.793 | 0.23 | |
| EPS15L1 | RUNDC3B | 0.793 | ||
| SMAP2 | PIK3C2A | 0.791 | 0.06 | |
| NUMB | SEC16A | 0.791 | ||
| SP1 | GAK | 0.788 | 0.032 | |
| MEA1 | AP2A1 | 0.787 | 0.052 | |
| AP2B1 | AFTPH | 0.787 | 0.226 | |
| AP1S1 | DENND1A | 0.785 | 0.056 | |
| AAK1 | SEC16A | 0.785 | ||
| NECAP2 | MEA1 | 0.783 | 0.03 |
mutually_exclusive (Q96CW1)
|
| KIF13A | AP1G2 | 0.783 | ||
| AP2A2 | MEA1 | 0.781 | 0.085 | |
| SYNRG | HIP1 | 0.781 | 0.073 | |
| NECAP1 | HIP1 | 0.781 | 0.092 | |
| NECAP1 | STAMBPL1 | 0.781 | 0.11 | |
| AP2M1 | STAMBP | 0.779 | 0.136 | |
| SEC24B | WNK1 | 0.778 | 0.128 | |
| SYNJ1 | HIP1 | 0.778 | 0.078 | |
| EPN1 | TNRC6A | 0.778 | 0.126 | |
| AP2A2 | SYNJ1 | 0.778 | 0.118 | |
| TNRC6A | NUMB | 0.777 | 0.104 | |
| HEATR5B | MEA1 | 0.777 | 0.044 | |
| EPN1 | AP1S1 | 0.776 | 0.028 | |
| FCHO2 | GAK | 0.775 | 0.092 | |
| FCHO2 | CLTCL1 | 0.773 | 0.08 | |
| AP2M1 | SEC16A | 0.772 | ||
| EPN1 | CLINT1 | 0.772 | 0.152 | |
| AP1G1 | STAMBPL1 | 0.768 | 0.146 | |
| NECAP2 | DENND1A | 0.768 | 0.122 | |
| AP1B1 | RUNDC3A | 0.766 | 0.06 | |
| FCHO2 | STAMBPL1 | 0.764 | 0.13 | |
| AP2A2 | GKN1 | 0.764 | ||
| FCHO2 | HIP1 | 0.764 | 0.158 | |
| AP2B1 | HEATR5B | 0.762 | 0.166 | |
| NECAP2 | FCHO2 | 0.761 | 0.042 |
structurally_consistent (Q96CW1)
|
| AP2M1 | ZNF106 | 0.76 | 0.1245 | |
| AP1B1 | DENND1A | 0.758 | 0.112 | |
| AP2A2 | GULP1 | 0.755 | 0.160597222222 | |
| CLTCL1 | REPS1 | 0.753 | 0.152 | |
| EPN1 | AP1M1 | 0.753 | 0.132 | |
| SYNJ1 | GULP1 | 0.752 | 0.062 | |
| TNRC6A | CLTCL1 | 0.748 | 0.174 | |
| AP2M1 | REPS2 | 0.747 | 0.138 | |
| EPN1 | CLTCL1 | 0.746 | 0.136 | |
| TNRC6A | EPS15 | 0.746 | 0.098 | |
| AP1M1 | HIP1 | 0.745 | 0.0646666666667 | |
| WNK1 | AP1G1 | 0.744 | 0.078 | |
| STAMBP | AAK1 | 0.741 | 0.07 | |
| AP2B1 | SEC24B | 0.738 | 0.25 | |
| FCHO2 | TNRC6A | 0.736 | 0.104 | |
| CLTCL1 | AAK1 | 0.736 | 0.138 | |
| EPS15 | SEC16A | 0.733 | ||
| ITSN1 | AP1S1 | 0.732 | ||
| NECAP2 | RUNDC3A | 0.729 | 0.07 | |
| PAAT | DENND1A | 0.729 | 0.134 | |
| KIF13A | MEA1 | 0.726 | ||
| CLTC | SEC16A | 0.723 | ||
| AP1AR | DENND1A | 0.722 | 0.092 | |
| AP2B1 | AP1AR | 0.72 | 0.188 | |
| CLINT1 | SEC16A | 0.717 | ||
| AP1G1 | COMT | 0.716 | 0.136 |
structurally_consistent (Q9BXS5)
|
| AP2A2 | STAMBP | 0.715 | 0.218 | |
| AP2M1 | AP1G2 | 0.715 | 0.068 | |
| AP1AR | HIP1 | 0.715 | 0.074 | |
| AP1S1 | BMP2K | 0.714 | 0.034 | |
| MEA1 | AAK1 | 0.713 | 0.03 | |
| AAGAB | AP1G2 | 0.71 | 0.054 |
structurally_consistent (dimer)
|
| WNK1 | CLINT1 | 0.709 | 0.114 | |
| STON2 | SEC16A | 0.706 | ||
| NECAP1 | AP1S2 | 0.705 | 0.124 | |
| EPS15L1 | BMP2K | 0.705 | 0.19 | |
| TNRC6A | SMAP2 | 0.703 | 0.054 | |
| AAGAB | FCHO2 | 0.702 | 0.04 | |
| BMP2K | AP1G1 | 0.7 | 0.086 | |
| EPN1 | AP2A1 | 0.699 | 0.338 | |
| NECAP1 | AP1G2 | 0.699 | 0.056 | |
| SYNRG | REPS1 | 0.688 | 0.124 | |
| AP2B1 | SYNRG | 0.686 | 0.220090909091 | |
| AP2S1 | NUMB | 0.682 | 0.086 | |
| STAMBP | EPS15 | 0.679 | 0.116 | |
| AP2B1 | SEC16A | 0.678 | ||
| AP1B1 | ZNF106 | 0.673 | 0.096 | |
| AP2B1 | CLTCL1 | 0.664 | 0.246 | |
| EPN1 | DNAJC6 | 0.663 | 0.172 | |
| TNRC6A | AP2A1 | 0.662 | 0.216 | |
| AP2A2 | NUMB | 0.661 | 0.1704 | |
| NECAP1 | MEA1 | 0.661 | 0.042 | |
| AP1G2 | COMT | 0.658 | 0.03 | |
| AAGAB | ITSN1 | 0.656 | ||
| REPS2 | BMP2K | 0.652 | 0.134 | |
| AP2S1 | AP1G1 | 0.65 | 0.158 |
structurally_consistent (dimer)
|
| SYNRG | SMAP2 | 0.648 | 0.098 | |
| ZNF106 | AAK1 | 0.641 | 0.056 | |
| NECAP1 | TNRC6A | 0.641 | 0.142 | |
| AP1G1 | NUMB | 0.638 | 0.068 | |
| SYNJ1 | EPS15 | 0.638 | 0.07 | |
| SEC24B | REPS1 | 0.636 | 0.092 | |
| TNRC6A | REPS1 | 0.632 | 0.12 | |
| AP1S2 | EPS15 | 0.629 | 0.072 | |
| MEA1 | BMP2K | 0.627 | 0.026 | |
| AP2A2 | PAAT | 0.627 | 0.172 | |
| AAGAB | AP1AR | 0.625 | 0.126 | |
| RUNDC3B | EPS15 | 0.625 | ||
| AP1S1 | HIP1 | 0.623 | 0.056 | |
| AP1S1 | AFTPH | 0.623 | 0.046 | |
| TNRC6A | WNK1 | 0.62 | 0.148 | |
| SEC24B | NUMB | 0.62 | 0.148 | |
| CCDC32 | AAK1 | 0.617 | 0.072 | |
| CCDC32 | ITSN1 | 0.617 | ||
| AP2S1 | NECAP1 | 0.615 | 0.082 |
structurally_consistent (dimer)
|
| AP1B1 | SMAP2 | 0.613 | 0.102 | |
| AP2S1 | AMPH | 0.613 | 0.092 | |
| HIP1 | AP1G1 | 0.612 | 0.046 | |
| RUNDC3B | AP2A1 | 0.611 | ||
| AP1M1 | SMAP2 | 0.611 | 0.042 | |
| AP1M1 | STON2 | 0.61 | 0.188 | |
| RALBP1 | DENND1A | 0.609 | 0.208 | |
| TNRC6A | HIP1 | 0.608 | 0.062 | |
| AP2B1 | KIF13A | 0.608 | ||
| AP1S1 | SMAP2 | 0.605 | 0.04 | |
| AP2S1 | DENND1A | 0.602 | 0.118 | |
| AP2M1 | RUNDC3B | 0.601 | ||
| MEA1 | REPS1 | 0.601 | 0.05 | |
| AAGAB | HEATR5B | 0.598 | 0.052 | |
| AP2B1 | RUNDC3B | 0.596 | ||
| ITSN2 | STON2 | 0.595 | 0.1 | |
| AP1G1 | CLINT1 | 0.592 | 0.286 | |
| AP1B1 | COMT | 0.592 | 0.16 |
structurally_consistent (Q9BXS5)
|
| SEC24B | HIP1 | 0.592 | 0.03 | |
| RALBP1 | CLTC | 0.591 | 0.24 | |
| AP2S1 | CLTCL1 | 0.59 | 0.118 | |
| EPN1 | AP2M1 | 0.589 | 0.308 | |
| FCHO2 | AP1M1 | 0.586 | 0.114 | |
| RALBP1 | HIP1 | 0.585 | 0.044 | |
| REPS1 | GAK | 0.583 | 0.168 | |
| EPN1 | GKN1 | 0.583 | ||
| AP2M1 | HIP1 | 0.582 | 0.152 | |
| AP2M1 | SMAP2 | 0.579 | 0.124 | |
| AP2A2 | DNAJC6 | 0.579 | 0.166 | |
| SYNRG | MEA1 | 0.578 | 0.034 | |
| NECAP1 | CLTC | 0.577 | 0.257142857143 | |
| EPS15L1 | AP1S2 | 0.574 | 0.072 | |
| RUNDC3B | CLINT1 | 0.573 | ||
| CCDC32 | FCHO2 | 0.572 | 0.052 | |
| SMAP2 | REPS1 | 0.571 | 0.046 | |
| AP1S1 | EPS15 | 0.569 | 0.096 | |
| AAGAB | AFTPH | 0.565 | 0.078 | |
| CCDC32 | EPS15 | 0.563 | 0.026 | |
| NECAP1 | STAMBP | 0.559 | 0.084 | |
| SMAP2 | SEC16A | 0.558 | ||
| RALBP1 | RUNDC3B | 0.558 | ||
| AAGAB | SYNRG | 0.554 | 0.104 | |
| DNAJC6 | HIP1 | 0.554 | 0.148 | |
| FCHO2 | PIK3C2A | 0.553 | 0.17 | |
| AP2A2 | AP1G1 | 0.548 | 0.0923333333333 |
structurally_consistent (dimer)
|
| AFTPH | CLINT1 | 0.539 | 0.168 | |
| AP2M1 | PAAT | 0.535 | 0.1 |
structurally_consistent (dimer)
|
| SMAP2 | HIP1 | 0.53 | 0.052 | |
| WNK1 | SEC16A | 0.528 | ||
| GKN1 | CLINT1 | 0.527 | ||
| SMAP2 | AP1G1 | 0.523 | 0.062 | |
| ITSN2 | AP1S3 | 0.522 | 0.068 | |
| EPN1 | AP1B1 | 0.52 | 0.382 | |
| RALBP1 | STAMBPL1 | 0.519 | 0.082 | |
| AAGAB | AAK1 | 0.517 | 0.066 | |
| AP2A2 | RUNDC3B | 0.517 | ||
| AP2S1 | RUNDC3B | 0.517 | ||
| AP1M1 | WNK1 | 0.513 | 0.144 | |
| AP1B1 | GULP1 | 0.51 | 0.088 | |
| REPS1 | NUMB | 0.509 | 0.094 | |
| NECAP2 | RUNDC3B | 0.502 | ||
| AP1B1 | STAMBPL1 | 0.499 | 0.05 | |
| EPN1 | GULP1 | 0.496 | 0.082 | |
| NECAP1 | KIF13A | 0.496 | ||
| AP1AR | KIF13A | 0.49 | ||
| NECAP2 | STON2 | 0.487 | 0.064 | |
| TNRC6A | GAK | 0.485 | 0.136 | |
| SEC24B | ZNF106 | 0.482 | 0.092 | |
| SEC24B | CLTC | 0.481 | 0.394 | |
| AP1S2 | RALBP1 | 0.48 | 0.118 | |
| CCDC32 | EPS15L1 | 0.475 | 0.202 | |
| AP2A2 | NECAP1 | 0.475 | 0.16 |
mutually_exclusive (P53680)
|
| SMAP2 | CLTCL1 | 0.473 | 0.064 | |
| PIK3C2A | GULP1 | 0.472 | 0.174 | |
| ITSN2 | AP1S1 | 0.471 | 0.074 | |
| RALBP1 | AP1S3 | 0.467 | 0.108 | |
| ITSN2 | AP1S2 | 0.467 | 0.082 | |
| RALBP1 | NUMB | 0.465 | 0.124 | |
| AAGAB | AMPH | 0.464 | 0.164 | |
| SYNJ1 | MEA1 | 0.463 | 0.032 | |
| SYNJ1 | CLINT1 | 0.463 | 0.098 | |
| AP2B1 | SMAP2 | 0.451 | 0.146 | |
| TNRC6A | AAK1 | 0.45 | 0.07 | |
| AP1S3 | AAK1 | 0.44 | 0.042 | |
| AP1AR | CLTC | 0.438 | 0.188 | |
| AP1S1 | GAK | 0.437 | 0.094 | |
| SMAP2 | AP2A1 | 0.437 | 0.14 | |
| SMAP2 | EPS15 | 0.435 | 0.038 | |
| SEC24B | STAMBPL1 | 0.434 | 0.064 | |
| AP1M2 | AP2A1 | 0.433 | 0.07 | |
| AP2M1 | CLTCL1 | 0.432 | 0.202 | |
| AP2M1 | DNAJC6 | 0.43 | 0.244 | |
| EPS15L1 | NECAP1 | 0.43 | 0.158 | |
| NECAP2 | AP1M1 | 0.428 | 0.108 | |
| AP1S3 | GULP1 | 0.428 | 0.04 | |
| AAGAB | EPS15 | 0.427 | 0.038 | |
| ZNF106 | REPS1 | 0.426 | 0.042 | |
| ITSN1 | SYNJ1 | 0.416 | ||
| AAGAB | EPS15L1 | 0.415 | 0.066 | |
| NECAP1 | AFTPH | 0.415 | 0.116 | |
| AP1AR | STAMBPL1 | 0.405 | 0.09 | |
| PAAT | SEC16A | 0.403 | ||
| AP1AR | AP1M2 | 0.402 | 0.05 |
mutually_exclusive (Q9BXS5)
|
| AP2A2 | DENND1A | 0.401 | 0.192 | |
| AP2S1 | STAMBPL1 | 0.397 | 0.086 | |
| AP1S1 | GULP1 | 0.397 | 0.062 | |
| SMAP2 | STON2 | 0.396 | 0.114 | |
| DNAJC6 | REPS1 | 0.396 | 0.182 | |
| AP1G1 | EPS15 | 0.393 | 0.072 |
mutually_exclusive (P53680)
|
| AP2S1 | PIK3C2A | 0.388 | 0.078 | |
| AP1AR | STAMBP | 0.388 | 0.1 | |
| AP1AR | AAK1 | 0.378 | 0.084 | |
| DENND1A | AP1G1 | 0.374 | 0.148 | |
| AP2A2 | AP1G2 | 0.374 | 0.108 | |
| EPN1 | AP2B1 | 0.369 | 0.41 | |
| AP2B1 | PAAT | 0.366 | 0.128 | |
| DNAJC6 | SEC16A | 0.365 | ||
| SYNJ1 | AP1AR | 0.364 | 0.072 | |
| AP1AR | NUMB | 0.364 | 0.092 | |
| AP1S3 | EPS15 | 0.363 | 0.046 | |
| GULP1 | AAK1 | 0.363 | 0.092 | |
| AP1B1 | WNK1 | 0.363 | 0.086 | |
| AP1S2 | BMP2K | 0.362 | 0.042 | |
| AP1S1 | WNK1 | 0.36 | 0.064 | |
| ITSN1 | NECAP1 | 0.36 | ||
| AP2S1 | STAMBP | 0.359 | 0.184 | |
| AP1S3 | COMT | 0.356 | 0.106 | |
| EPN1 | SYNRG | 0.354 | 0.112 | |
| NECAP2 | AP1S1 | 0.353 | 0.048 | |
| ITSN2 | NECAP1 | 0.353 | 0.092 | |
| NECAP1 | GAK | 0.351 | 0.092 |
structurally_consistent (Q10567)
|
| SYNJ1 | SMAP2 | 0.351 | 0.14 | |
| SEC24B | GAK | 0.343 | 0.128 | |
| AP1S1 | HEATR5B | 0.34 | 0.04 | |
| EPS15L1 | AP1S3 | 0.34 | 0.12 | |
| AP2M1 | WNK1 | 0.334 | 0.08 | |
| AP2M1 | AP1M1 | 0.333 | 0.3 | |
| RALBP1 | GAK | 0.333 | 0.17 | |
| AP2S1 | CLTC | 0.331 | 0.566 | |
| MEA1 | DENND1A | 0.33 | 0.1 | |
| FCHO2 | CLINT1 | 0.324 | 0.144 | |
| EPS15L1 | AP1S1 | 0.322 | 0.068 | |
| AP2A2 | AP1M2 | 0.317 | 0.114 | |
| ITSN1 | DENND1A | 0.317 | ||
| NECAP2 | AP1S2 | 0.315 | 0.05 | |
| AP1S2 | CLTC | 0.311 | 0.2 | |
| AP2A2 | STAMBPL1 | 0.309 | 0.276 | |
| EPN1 | SEC16A | 0.307 | ||
| CCDC32 | STON2 | 0.305 | 0.06 | |
| RUNDC3B | REPS1 | 0.303 | ||
| AP1S3 | BMP2K | 0.302 | 0.04 | |
| NECAP1 | HEATR5B | 0.302 | 0.062 | |
| NECAP2 | AP1S3 | 0.3 | 0.054 | |
| ITSN2 | AP1G1 | 0.3 | 0.096 | |
| AP1G2 | STON2 | 0.299 | 0.136 | |
| GULP1 | AP1G1 | 0.297 | 0.126 | |
| ITSN2 | TNRC6A | 0.294 | 0.158 | |
| ITSN1 | AP1G2 | 0.293 | ||
| SYNJ1 | ZNF106 | 0.292 | 0.116 | |
| FCHO2 | STAMBP | 0.289 | 0.114 | |
| ZNF106 | HIP1 | 0.288 | 0.09 | |
| NECAP1 | CLTCL1 | 0.288 | 0.122 | |
| SP1 | BMP2K | 0.287 | 0.024 | |
| SYNJ1 | AP1S2 | 0.287 | 0.098 | |
| AP1S2 | REPS1 | 0.285 | 0.048 | |
| SYNJ1 | PIK3C2A | 0.284 | 0.138 | |
| RALBP1 | SYNRG | 0.281 | 0.102 | |
| AAGAB | AP1M1 | 0.277 | 0.114 | |
| RALBP1 | AP1M2 | 0.277 | 0.056 | |
| AP1M1 | BMP2K | 0.277 | 0.128 | |
| NECAP2 | NUMB | 0.269 | 0.056 | |
| AP1AR | CLINT1 | 0.267 | 0.086 | |
| DENND1A | GULP1 | 0.267 | 0.116 | |
| AP2S1 | AP1G2 | 0.266 | 0.04 | |
| SYNJ1 | SEC24B | 0.265 | 0.128 | |
| SYNRG | WNK1 | 0.263 | 0.158 | |
| AP2S1 | GULP1 | 0.26 | 0.074 | |
| AP1M1 | STAMBPL1 | 0.257 | 0.11 | |
| FCHO2 | AP1G2 | 0.257 | 0.038 | |
| AP2M1 | GAK | 0.256 | 0.198 | |
| CLTCL1 | GULP1 | 0.248 | 0.114 | |
| NECAP1 | SMAP2 | 0.248 | 0.044 | |
| HIP1 | GULP1 | 0.247 | 0.108 | |
| AP1S3 | REPS1 | 0.247 | 0.072 | |
| GULP1 | STON2 | 0.243 | 0.086 | |
| SEC24B | TNRC6A | 0.241 | 0.132 | |
| AAGAB | RALBP1 | 0.24 | 0.034 | |
| ITSN2 | MEA1 | 0.239 | 0.04 | |
| SEC24B | STAMBP | 0.238 | 0.064 | |
| AP1M1 | DENND1A | 0.237 | 0.216 | |
| ITSN2 | GULP1 | 0.236 | 0.048 | |
| AP1S3 | NUMB | 0.233 | 0.046 | |
| FCHO2 | SMAP2 | 0.232 | 0.038 | |
| SP1 | DENND1A | 0.232 | 0.072 | |
| SMAP2 | DENND1A | 0.232 | 0.068 | |
| SYNRG | STAMBPL1 | 0.232 | 0.086 | |
| AP1S1 | ZNF106 | 0.232 | 0.072 | |
| SP1 | NUMB | 0.232 | 0.044 | |
| SYNRG | STAMBP | 0.232 | 0.068 | |
| AP1B1 | STAMBP | 0.232 | 0.128 | |
| ITSN2 | RALBP1 | 0.231 | 0.07 | |
| FCHO2 | GULP1 | 0.23 | 0.068 | |
| NECAP2 | AP1M2 | 0.228 | 0.014 | |
| SMAP2 | CLTC | 0.228 | 0.132 | |
| GULP1 | CLINT1 | 0.225 | 0.176 | |
| AP1M1 | EPS15 | 0.223 | 0.138 | |
| AP1B1 | CLTCL1 | 0.22 | 0.186 | |
| AP1AR | PIK3C2A | 0.22 | 0.1 | |
| NECAP2 | GULP1 | 0.219 | 0.018 | |
| NECAP1 | GULP1 | 0.219 | 0.072 | |
| AP1B1 | TNRC6A | 0.218 | 0.192 | |
| KIF13A | BMP2K | 0.215 | ||
| GKN1 | CLTC | 0.214 | ||
| CCDC32 | REPS1 | 0.209 | 0.094 | |
| AP1S2 | AAK1 | 0.207 | 0.084 | |
| AP1S2 | GULP1 | 0.207 | 0.05 | |
| EPS15L1 | AP1G2 | 0.206 | 0.04 | |
| AP1G2 | EPS15 | 0.206 | 0.05 | |
| AP1B1 | PIK3C2A | 0.205 | 0.148 | |
| ZNF106 | STAMBP | 0.203 | 0.04 | |
| AP2A2 | PIK3C2A | 0.203 | 0.176 | |
| EPN1 | CLTC | 0.201 | 0.328 | |
| EPS15L1 | NUMB | 0.198 | 0.072 | |
| FCHO2 | SYNRG | 0.197 | 0.122 | |
| SP1 | HIP1 | 0.192 | 0.022 | |
| SP1 | STAMBPL1 | 0.192 | 0.068 | |
| AP1S1 | STAMBPL1 | 0.192 | 0.04 | |
| NECAP1 | PAAT | 0.192 | 0.08 |
mutually_exclusive (Q96CW1)
|
| AP1S1 | STAMBP | 0.192 | 0.108 | |
| AP1S2 | NUMB | 0.19 | 0.068 | |
| AP1G1 | STAMBP | 0.189 | 0.282 | |
| KIF13A | STON2 | 0.188 | ||
| KIF13A | GULP1 | 0.188 | ||
| KIF13A | AAK1 | 0.188 | ||
| FCHO2 | KIF13A | 0.188 | ||
| GULP1 | STAMBPL1 | 0.188 | 0.098 | |
| AP1AR | GULP1 | 0.188 | 0.08 | |
| REPS2 | GULP1 | 0.187 | 0.078 | |
| BMP2K | RUNDC3B | 0.187 | ||
| TNRC6A | AP1G1 | 0.187 | 0.13 | |
| EPN1 | AP2A2 | 0.186 | 0.218 | |
| RALBP1 | KIF13A | 0.184 | ||
| AP1B1 | SEC16A | 0.182 | ||
| SYNJ1 | CLTCL1 | 0.18 | 0.168 | |
| AAGAB | NECAP2 | 0.18 | 0.03 |
mutually_exclusive (P53680)
|
| AP1AR | MEA1 | 0.178 | 0.062 | |
| EPS15L1 | DENND1A | 0.178 | 0.202 | |
| SYNJ1 | GAK | 0.176 | 0.156 | |
| KIF13A | REPS1 | 0.173 | ||
| CCDC32 | NECAP2 | 0.172 | 0.086 |
mutually_exclusive (P53680)
|
| CCDC32 | AP1S3 | 0.172 | 0.064 | |
| EPS15L1 | CLINT1 | 0.17 | 0.228 | |
| AP2S1 | WNK1 | 0.169 | 0.05 | |
| AP1M1 | STAMBP | 0.167 | 0.118 | |
| AP1B1 | RUNDC3B | 0.167 | ||
| AP2A2 | HIP1 | 0.166 | 0.106 | |
| KIF13A | NUMB | 0.165 | ||
| CCDC32 | RALBP1 | 0.164 | 0.128 | |
| CCDC32 | BMP2K | 0.164 | 0.13 | |
| CCDC32 | AP1G1 | 0.164 | 0.036 | |
| CLTCL1 | DNAJC6 | 0.161 | 0.118 | |
| AP1M2 | GAK | 0.161 | 0.1 | |
| RALBP1 | AP1G2 | 0.161 | 0.04 | |
| AFTPH | GAK | 0.16 | 0.21 | |
| SYNJ1 | AP1M2 | 0.159 | 0.068 | |
| AFTPH | WNK1 | 0.158 | 0.104 | |
| PAAT | WNK1 | 0.157 | 0.078 | |
| AP2S1 | SMAP2 | 0.154 | 0.034 | |
| AP2S1 | AP1M2 | 0.153 | 0.062 | |
| ITSN1 | RUNDC3A | 0.152 | ||
| AP1S1 | PIK3C2A | 0.151 | 0.062 | |
| MEA1 | GULP1 | 0.151 | 0.026 | |
| SYNJ1 | TNRC6A | 0.151 | 0.176 | |
| AP1M1 | AAK1 | 0.15 | 0.132 | |
| DENND1A | ZNF106 | 0.149 | 0.062 | |
| NECAP1 | PIK3C2A | 0.149 | 0.11 | |
| ITSN2 | NUMB | 0.145 | 0.102 | |
| SYNJ1 | KIF13A | 0.144 | ||
| ITSN2 | KIF13A | 0.144 | ||
| AP1M1 | TNRC6A | 0.143 | 0.176 | |
| CCDC32 | AP1S2 | 0.143 | 0.1 | |
| ITSN1 | GULP1 | 0.142 | ||
| FCHO2 | PAAT | 0.141 | 0.042 | |
| ITSN2 | DENND1A | 0.139 | 0.108 | |
| AP2A2 | AP1M1 | 0.139 | 0.274 | |
| AFTPH | PIK3C2A | 0.138 | 0.068 | |
| AAGAB | STON2 | 0.138 | 0.082 | |
| PAAT | SEC24B | 0.138 | 0.134 | |
| AP2A2 | CLTCL1 | 0.136 | 0.326 | |
| MEA1 | NUMB | 0.135 | 0.05 | |
| AFTPH | STON2 | 0.135 | 0.086 | |
| GULP1 | STAMBP | 0.133 | 0.072 | |
| ITSN2 | BMP2K | 0.131 | 0.1 | |
| SYNRG | CLINT1 | 0.131 | 0.096 | |
| AP1G2 | AP2A1 | 0.131 | 0.152 | |
| REPS2 | DENND1A | 0.131 | 0.11 | |
| AP1M1 | GAK | 0.131 | 0.09 | |
| ITSN2 | SYNJ1 | 0.131 | 0.112 | |
| PAAT | TNRC6A | 0.131 | 0.094 | |
| AP1M1 | NUMB | 0.131 | 0.06 | |
| AP1M2 | DENND1A | 0.13 | 0.1 | |
| AP2A2 | AP1AR | 0.13 | 0.118 | |
| AP2S1 | AP1AR | 0.13 | 0.108 | |
| AP1AR | RALBP1 | 0.13 | 0.22 | |
| AFTPH | REPS1 | 0.129 | 0.11 | |
| AFTPH | EPS15 | 0.129 | 0.068 | |
| AP1M2 | AAK1 | 0.127 | 0.042 | |
| NECAP1 | SEC16A | 0.126 | ||
| AFTPH | HIP1 | 0.126 | 0.068 | |
| SYNRG | EPS15 | 0.126 | 0.14 | |
| AP1AR | AP2A1 | 0.126 | 0.076 | |
| SEC24B | AFTPH | 0.125 | 0.162 | |
| SYNRG | BMP2K | 0.124 | 0.146 | |
| AP2B1 | GULP1 | 0.124 | 0.11 | |
| AP2S1 | HIP1 | 0.123 | 0.066 | |
| TNRC6A | SYNRG | 0.123 | 0.114 | |
| ITSN1 | AP1M1 | 0.123 | ||
| GULP1 | AP2A1 | 0.122 | 0.05 | |
| FCHO2 | ZNF106 | 0.121 | 0.122 | |
| ITSN2 | AAK1 | 0.121 | 0.074 | |
| AP1AR | GAK | 0.12 | 0.148 | |
| AP1M1 | CLTCL1 | 0.12 | 0.144 | |
| AP2S1 | TNRC6A | 0.118 | 0.056 | |
| AP1M2 | HIP1 | 0.117 | 0.128 | |
| AP2S1 | AP1M1 | 0.117 | 0.34 | |
| AP1M1 | AP2A1 | 0.117 | 0.308 | |
| AP1M2 | STAMBPL1 | 0.116 | 0.048 | |
| AP2M1 | AP1AR | 0.116 | 0.12 | |
| GULP1 | CLTC | 0.116 | 0.22 | |
| AAGAB | BMP2K | 0.116 | 0.082 | |
| HEATR5B | EPS15 | 0.114 | 0.064 | |
| EPS15L1 | SYNJ1 | 0.114 | 0.16 | |
| AP2S1 | GAK | 0.113 | 0.114 | |
| NECAP1 | AP1AR | 0.113 | 0.106 | |
| AP2M1 | AP1M2 | 0.112 | 0.028 |
mutually_exclusive (P63010)
|
| SYNRG | NUMB | 0.109 | 0.1 | |
| SP1 | CLINT1 | 0.108 | 0.148 | |
| PAAT | REPS2 | 0.107 | 0.134 | |
| AAGAB | AP1M2 | 0.107 | 0.1 | |
| MEA1 | COMT | 0.105 | 0.036 |
mutually_exclusive (Q9BXS5)
|
| NECAP2 | SYNJ1 | 0.105 | 0.134 | |
| AP1B1 | SEC24B | 0.104 | 0.178 | |
| SYNJ1 | WNK1 | 0.103 | 0.118 | |
| AAGAB | NECAP1 | 0.102 | 0.118 |
mutually_exclusive (P53680)
|
| HEATR5B | STON2 | 0.102 | 0.066 | |
| FCHO2 | HEATR5B | 0.102 | 0.07 | |
| GULP1 | EPS15 | 0.102 | 0.06 | |
| FCHO2 | AFTPH | 0.101 | 0.082 | |
| AFTPH | NUMB | 0.101 | 0.142 | |
| AP1M2 | STON2 | 0.1 | 0.112 | |
| AP1S1 | TNRC6A | 0.098 | 0.124 | |
| AP1G2 | BMP2K | 0.098 | 0.048 | |
| AP1B1 | GAK | 0.097 | 0.342 |
structurally_consistent (dimer)
|
| AAGAB | REPS1 | 0.096 | 0.044 | |
| AP2A2 | CLTC | 0.093 | 0.546 | |
| NECAP2 | AP1G2 | 0.093 | 0.034 | |
| EPS15L1 | AP1M1 | 0.093 | 0.21 | |
| ITSN2 | AFTPH | 0.093 | 0.064 | |
| EPS15L1 | GULP1 | 0.089 | 0.144 | |
| AP1B1 | DNAJC6 | 0.089 | 0.148 | |
| ITSN1 | AFTPH | 0.087 | ||
| AP2A2 | COMT | 0.087 | 0.27 | |
| AP2B1 | DNAJC6 | 0.086 | 0.248 | |
| AP1M2 | STAMBP | 0.086 | 0.0740970873786 | |
| GULP1 | GAK | 0.086 | 0.062 | |
| AP1M2 | GULP1 | 0.084 | 0.066 | |
| AP1M2 | NUMB | 0.083 | 0.028 | |
| AP1M2 | REPS1 | 0.083 | 0.066 | |
| PAAT | STON2 | 0.082 | 0.096 | |
| EPN1 | ZNF106 | 0.082 | 0.07 | |
| AP1AR | REPS1 | 0.082 | 0.072 | |
| TNRC6A | RALBP1 | 0.082 | 0.168 | |
| REPS2 | CLINT1 | 0.081 | 0.18 | |
| HEATR5B | BMP2K | 0.08 | 0.162 | |
| AP1S2 | REPS2 | 0.08 | 0.086 | |
| REPS2 | AP1G1 | 0.08 | 0.094 |
mutually_exclusive (P53680)
|
| SP1 | SMAP2 | 0.08 | 0.016 | |
| AP1G1 | CLTC | 0.079 | 0.896 | |
| ITSN1 | GAK | 0.079 | ||
| AP2M1 | AFTPH | 0.078 | 0.244 | |
| AP1G1 | GAK | 0.078 | 0.16 | |
| SYNRG | STON2 | 0.077 | 0.06 | |
| EPN1 | AP2S1 | 0.076 | 0.29 | |
| SYNJ1 | AMPH | 0.076 | 0.198 | |
| AAGAB | KIF13A | 0.076 | ||
| AP1AR | BMP2K | 0.076 | 0.112 | |
| NECAP2 | KIF13A | 0.076 | ||
| AP2A1 | COMT | 0.076 | 0.128 | |
| ITSN1 | AP1M2 | 0.076 | ||
| AP1M2 | SEC16A | 0.075 | ||
| SYNJ1 | AFTPH | 0.075 | 0.112 | |
| AP1G2 | REPS1 | 0.075 | 0.044 | |
| AP1AR | CLTCL1 | 0.074 | 0.13 | |
| RALBP1 | AFTPH | 0.074 | 0.224 | |
| AP2M1 | COMT | 0.074 | 0.242 | |
| SYNRG | DENND1A | 0.074 | 0.048 | |
| REPS2 | KIF13A | 0.073 | ||
| EPS15L1 | HEATR5B | 0.073 | 0.188 | |
| AP1M2 | PIK3C2A | 0.073 | 0.092 | |
| TNRC6A | ZNF106 | 0.073 | 0.136 | |
| AFTPH | COMT | 0.073 | 0.036 | |
| ITSN2 | AP1G2 | 0.073 | 0.044 | |
| AP1G2 | AAK1 | 0.073 | 0.046 | |
| SEC24B | RALBP1 | 0.072 | 0.184 | |
| RALBP1 | CLTCL1 | 0.071 | 0.1152 | |
| AFTPH | AP2A1 | 0.071 | 0.134 | |
| AAGAB | MEA1 | 0.07 | 0.116 | |
| NECAP1 | REPS2 | 0.07 | 0.104 | |
| REPS2 | AP1S3 | 0.07 | 0.096 | |
| ITSN2 | SYNRG | 0.069 | 0.102 | |
| RALBP1 | COMT | 0.069 | 0.0961333333333 | |
| RALBP1 | HEATR5B | 0.069 | 0.162 | |
| FCHO2 | REPS2 | 0.068 | 0.056 | |
| AP1S1 | REPS2 | 0.068 | 0.074 | |
| REPS2 | STON2 | 0.068 | 0.084 | |
| AP2S1 | HEATR5B | 0.068 | 0.1 | |
| FCHO2 | AP1M2 | 0.068 | 0.034 | |
| SYNRG | AP2A1 | 0.068 | 0.21332 | |
| REPS2 | MEA1 | 0.067 | 0.082 | |
| SYNJ1 | REPS2 | 0.066 | 0.052 | |
| AP1B1 | CLTC | 0.066 | 0.677 | |
| SYNRG | COMT | 0.066 | 0.076 | |
| EPS15L1 | AFTPH | 0.065 | 0.222 | |
| HEATR5B | AP2A1 | 0.064 | 0.198 | |
| AP1M2 | EPS15 | 0.064 | 0.122 | |
| EPS15L1 | AP1M2 | 0.064 | 0.11 | |
| AP1AR | SEC16A | 0.064 | ||
| EPN1 | AP1AR | 0.064 | 0.042 | |
| ITSN1 | NUMB | 0.064 | ||
| AP2B1 | REPS2 | 0.063 | 0.14 | |
| SP1 | STON2 | 0.063 | 0.04 | |
| SP1 | CLTCL1 | 0.063 | 0.042 | |
| ZNF106 | AP1G1 | 0.063 | 0.096 | |
| AP1S1 | CLTCL1 | 0.063 | 0.124 | |
| NECAP2 | COMT | 0.062 | 0.048 | |
| SYNJ1 | SEC16A | 0.062 | ||
| SYNJ1 | AP1G2 | 0.061 | 0.042 | |
| AP2A2 | AFTPH | 0.061 | 0.148 | |
| EPN1 | SP1 | 0.06 | 0.042 | |
| SP1 | PIK3C2A | 0.06 | 0.04 | |
| AP2S1 | SEC16A | 0.059 | ||
| ITSN2 | HIP1 | 0.059 | 0.066 | |
| AP2A2 | GAK | 0.059 | 0.246 | |
| RALBP1 | WNK1 | 0.057 | 0.27 | |
| PIK3C2A | AP1G1 | 0.057 | 0.092 | |
| AAGAB | CLINT1 | 0.057 | 0.068 | |
| EPN1 | ITSN2 | 0.057 | 0.034 | |
| EPN1 | AP1S2 | 0.056 | 0.086 | |
| AP2S1 | KIF13A | 0.055 | ||
| NECAP1 | COMT | 0.055 | 0.036 | |
| SYNRG | PIK3C2A | 0.055 | 0.062 | |
| KIF13A | DENND1A | 0.055 | ||
| AP2A2 | REPS2 | 0.054 | 0.182 | |
| AP1M1 | ZNF106 | 0.053 | 0.154 | |
| AP1S2 | DENND1A | 0.053 | 0.108 | |
| ITSN2 | COMT | 0.051 | 0.07 | |
| STON2 | COMT | 0.05 | 0.216 | |
| SYNRG | AAK1 | 0.05 | 0.098 | |
| ITSN1 | KIF13A | 0.05 | ||
| ITSN1 | RUNDC3B | 0.05 | ||
| CCDC32 | AP1G2 | 0.05 | 0.06 | |
| HEATR5B | COMT | 0.05 | 0.028 | |
| NECAP1 | ZNF106 | 0.049 | 0.088 | |
| AP2A2 | KIF13A | 0.049 | ||
| AP1M1 | CLINT1 | 0.049 | 0.186 | |
| ITSN2 | HEATR5B | 0.048 | 0.084 | |
| AP2S1 | AFTPH | 0.048 | 0.114 | |
| ITSN1 | HEATR5B | 0.047 | ||
| AP2B1 | SP1 | 0.047 | 0.126 | |
| AP1M1 | CLTC | 0.046 | 0.536 | |
| AP1S3 | DENND1A | 0.046 | 0.068 | |
| EPN1 | REPS2 | 0.045 | 0.132 | |
| EPN1 | KIF13A | 0.045 | ||
| AP1G2 | NUMB | 0.045 | 0.052 | |
| SEC24B | SYNRG | 0.045 | 0.13 | |
| NECAP2 | PIK3C2A | 0.045 | 0.05 | |
| EPS15L1 | KIF13A | 0.045 | ||
| REPS2 | NUMB | 0.044 | 0.108 | |
| KIF13A | EPS15 | 0.044 | ||
| KIF13A | AP2A1 | 0.044 | ||
| AP2S1 | ZNF106 | 0.044 | 0.084 | |
| SYNJ1 | CLTC | 0.044 | 0.354 | |
| AP1B1 | REPS2 | 0.043 | 0.164 | |
| CCDC32 | AP1S1 | 0.043 | 0.06 | |
| HEATR5B | CLINT1 | 0.042 | 0.164 | |
| AP1M2 | BMP2K | 0.042 | 0.104 | |
| ITSN1 | SEC24B | 0.042 | ||
| SYNJ1 | HEATR5B | 0.042 | 0.086 | |
| SYNRG | SEC16A | 0.04 | ||
| EPN1 | NECAP2 | 0.04 | 0.058 | |
| FCHO2 | COMT | 0.039 | 0.058 | |
| AMPH | CLINT1 | 0.038 | 0.09 | |
| HEATR5B | NUMB | 0.038 | 0.05 | |
| ITSN2 | REPS1 | 0.037 | 0.042 | |
| CLTC | COMT | 0.037 | 0.472 | |
| MEA1 | CLTC | 0.037 | 0.186 | |
| AP2A2 | HEATR5B | 0.037 | 0.282818181818 | |
| AP1M1 | GULP1 | 0.036 | 0.112 | |
| AFTPH | BMP2K | 0.036 | 0.154 | |
| RALBP1 | ZNF106 | 0.036 | 0.104 | |
| AP2S1 | COMT | 0.036 | 0.078 | |
| REPS2 | EPS15 | 0.036 | 0.186 | |
| AAGAB | CLTC | 0.035 | 0.222 | |
| AFTPH | AAK1 | 0.035 | 0.112 | |
| AP2S1 | SYNRG | 0.034 | 0.104 | |
| EPN1 | AP1S3 | 0.034 | 0.042 | |
| AFTPH | DENND1A | 0.033 | 0.096 | |
| AP1S1 | CLTC | 0.032 | 0.342 | |
| AP1M1 | DNAJC6 | 0.032 | 0.328 | |
| AFTPH | CLTC | 0.032 | 0.196 | |
| NUMB | COMT | 0.032 | 0.018 | |
| CLTCL1 | AP1G1 | 0.031 | 0.16 | |
| DNAJC6 | EPS15 | 0.031 | 0.078 | |
| AP1M2 | RUNDC3A | 0.031 | ||
| ITSN1 | REPS2 | 0.031 | ||
| AP1M1 | PIK3C2A | 0.03 | 0.118 | |
| SYNJ1 | COMT | 0.03 | 0.042 | |
| AP2A2 | SYNRG | 0.03 | 0.114428571429 | |
| AP1M2 | WNK1 | 0.03 | 0.046 | |
| EPN1 | AAGAB | 0.03 | 0.038 | |
| DNAJC6 | AP1G1 | 0.03 | 0.32 | |
| ITSN2 | NECAP2 | 0.029 | 0.07 | |
| AP1G2 | CLTC | 0.029 | 0.145 | |
| SP1 | AP1M2 | 0.029 | 0.034 | |
| AP2S1 | DNAJC6 | 0.029 | 0.13 | |
| AP1M2 | CLINT1 | 0.029 | 0.048 | |
| REPS2 | AP2A1 | 0.028 | 0.15 | |
| ITSN1 | COMT | 0.028 | ||
| MEA1 | CLINT1 | 0.028 | 0.048 | |
| SP1 | SYNRG | 0.027 | 0.19 | |
| SP1 | SEC16A | 0.026 | ||
| AP1M2 | SMAP2 | 0.026 | 0.042 | |
| SYNRG | ZNF106 | 0.026 | 0.064 | |
| HEATR5B | SEC16A | 0.025 | ||
| ITSN2 | GAK | 0.025 | 0.094 | |
| HEATR5B | REPS1 | 0.025 | 0.036 | |
| SP1 | EPS15 | 0.025 | 0.066 | |
| AP2M1 | SYNRG | 0.025 | 0.16 | |
| AP1S3 | SEC16A | 0.024 | ||
| ITSN2 | CCDC32 | 0.024 | 0.05 | |
| PAAT | ZNF106 | 0.023 | 0.098 | |
| SP1 | CLTC | 0.023 | 0.196 | |
| EPS15L1 | SEC24B | 0.023 | 0.156 | |
| AP1B1 | PAAT | 0.022 | 0.13 | |
| AP2M1 | HEATR5B | 0.022 | 0.11 | |
| SYNRG | CLTCL1 | 0.022 | 0.064 | |
| AP2A2 | ZNF106 | 0.022 | 0.204597222222 | |
| AP1G2 | PIK3C2A | 0.022 | 0.056 | |
| ITSN1 | CLINT1 | 0.022 | ||
| AFTPH | GULP1 | 0.022 | 0.036 | |
| HEATR5B | PIK3C2A | 0.022 | 0.098 | |
| AP2A2 | SMAP2 | 0.021 | 0.144 | |
| GKN1 | AP2A1 | 0.021 | ||
| AP1B1 | GKN1 | 0.021 | ||
| REPS2 | SYNRG | 0.021 | 0.184 | |
| KIF13A | SEC16A | 0.02 | ||
| ITSN2 | AAGAB | 0.02 | 0.042 | |
| HEATR5B | CLTC | 0.02 | 0.244 | |
| GULP1 | SEC16A | 0.02 | ||
| AP1M1 | SEC16A | 0.02 | ||
| ITSN2 | AP1M1 | 0.02 | 0.096 | |
| ITSN2 | REPS2 | 0.019 | 0.126 | |
| AP2A2 | SEC16A | 0.019 | ||
| SMAP2 | COMT | 0.018 | 0.032 | |
| NECAP2 | REPS2 | 0.018 | 0.076 | |
| RALBP1 | SEC16A | 0.018 | ||
| DNAJC6 | AP2A1 | 0.018 | 0.172 | |
| AP1G2 | SEC16A | 0.017 | ||
| AP1M2 | DNAJC6 | 0.017 | 0.066 | |
| AP1G1 | SEC16A | 0.017 | ||
| TNRC6A | AFTPH | 0.017 | 0.122 | |
| PAAT | EPS15 | 0.017 | 0.052 | |
| AP1M1 | PAAT | 0.017 | 0.106 | |
| REPS1 | COMT | 0.016 | 0.078 | |
| AP1S3 | ZNF106 | 0.016 | 0.068 | |
| AAGAB | COMT | 0.016 | 0.052 | |
| ITSN2 | WNK1 | 0.016 | 0.1 | |
| EPN1 | AFTPH | 0.016 | 0.204 | |
| AP2S1 | GKN1 | 0.016 | ||
| SEC24B | MEA1 | 0.016 | 0.068 | |
| ITSN1 | PIK3C2A | 0.016 | ||
| AP1S3 | CLTC | 0.015 | 0.234 | |
| EPS15L1 | REPS2 | 0.015 | 0.202 | |
| AP1S2 | HIP1 | 0.015 | 0.084 | |
| EPN1 | COMT | 0.015 | 0.038 | |
| AMPH | CLTC | 0.015 | 0.31 | |
| CLTCL1 | COMT | 0.015 | 0.1 | |
| REPS2 | AP1G2 | 0.015 | 0.04 | |
| AP1G2 | GULP1 | 0.015 | 0.038 | |
| TNRC6A | DNAJC6 | 0.015 | 0.158 | |
| ITSN2 | SEC24B | 0.015 | 0.168 | |
| NECAP2 | CLINT1 | 0.015 | 0.084 | |
| EPN1 | AP1M2 | 0.014 | 0.062 | |
| EPN1 | MEA1 | 0.014 | 0.044 | |
| SEC24B | AP1S3 | 0.014 | 0.136 | |
| REPS2 | WNK1 | 0.014 | 0.114 | |
| PAAT | AP1G1 | 0.014 | 0.172 | |
| EPS15L1 | SYNRG | 0.014 | 0.116 | |
| AP1S2 | PIK3C2A | 0.014 | 0.048 | |
| EPS15 | COMT | 0.014 | 0.038 | |
| ITSN1 | HIP1 | 0.013 | ||
| AP1S1 | SEC16A | 0.013 | ||
| EPN1 | ITSN1 | 0.013 | ||
| TNRC6A | COMT | 0.013 | 0.11 | |
| HEATR5B | AAK1 | 0.013 | 0.09 | |
| PAAT | COMT | 0.013 | 0.068 | |
| EPS15L1 | TNRC6A | 0.013 | 0.16 | |
| AMPH | EPS15 | 0.013 | 0.09 | |
| AP2A2 | SEC24B | 0.013 | 0.168 | |
| AP1G2 | GAK | 0.012 | 0.068 | |
| AAGAB | TNRC6A | 0.012 | 0.126 | |
| GKN1 | REPS1 | 0.012 | ||
| AP1S2 | SMAP2 | 0.012 | 0.054 | |
| SMAP2 | GULP1 | 0.012 | 0.038 | |
| SP1 | AP2A1 | 0.012 | 0.084 | |
| KIF13A | PIK3C2A | 0.012 | ||
| ITSN1 | WNK1 | 0.012 | ||
| ITSN2 | PIK3C2A | 0.012 | 0.116 | |
| KIF13A | CLINT1 | 0.011 | ||
| TNRC6A | HEATR5B | 0.011 | 0.102 | |
| ITSN1 | SYNRG | 0.011 | ||
| SP1 | TNRC6A | 0.011 | 0.106 | |
| AAK1 | COMT | 0.011 | 0.038 | |
| REPS2 | HIP1 | 0.011 | 0.056 | |
| ITSN2 | AP1M2 | 0.011 | 0.054 | |
| EPN1 | AP1G2 | 0.011 | 0.038 | |
| TNRC6A | AP1S3 | 0.011 | 0.102 | |
| SP1 | COMT | 0.011 | 0.02 | |
| PAAT | MEA1 | 0.011 | 0.056 |
mutually_exclusive (Q96CW1)
|
| AAGAB | SEC24B | 0.011 | 0.06 | |
| CCDC32 | TNRC6A | 0.01 | 0.124 | |
| AP1M2 | ZNF106 | 0.01 | 0.092 | |
| PAAT | SMAP2 | 0.01 | 0.08 | |
| ITSN2 | SMAP2 | 0.01 | 0.02 | |
| SYNRG | GAK | 0.01 | 0.104 | |
| BMP2K | COMT | 0.01 | 0.046 | |
| SEC24B | AP1S2 | 0.01 | 0.138 | |
| AFTPH | SMAP2 | 0.01 | 0.07 | |
| TNRC6A | RUNDC3A | 0.01 | 0.09 | |
| RUNDC3A | CLTC | 0.01 | 0.154 | |
| ITSN1 | TNRC6A | 0.01 | ||
| ITSN1 | SEC16A | 0.009 | ||
| SYNRG | CLTC | 0.009 | 0.25 | |
| AMPH | COMT | 0.009 | 0.124 | |
| KIF13A | COMT | 0.009 | ||
| MEA1 | WNK1 | 0.009 | 0.05 | |
| MEA1 | ZNF106 | 0.009 | 0.086 | |
| GULP1 | COMT | 0.009 | 0.09 | |
| REPS2 | SMAP2 | 0.008 | 0.068 | |
| NECAP2 | SYNRG | 0.008 | 0.1 | |
| AFTPH | SEC16A | 0.008 | ||
| TNRC6A | MEA1 | 0.008 | 0.132 | |
| FCHO2 | SP1 | 0.008 | 0.042 | |
| EPS15L1 | COMT | 0.008 | 0.09 | |
| REPS2 | PIK3C2A | 0.008 | 0.066 | |
| HEATR5B | WNK1 | 0.008 | 0.06 | |
| REPS2 | GAK | 0.008 | 0.144 | |
| EPS15L1 | SMAP2 | 0.008 | 0.036 | |
| SEC24B | DNAJC6 | 0.008 | 0.166 | |
| TNRC6A | GULP1 | 0.007 | 0.08 | |
| AP2B1 | COMT | 0.007 | 0.172 |
structurally_consistent (Q9BXS5)
|
| SEC24B | SP1 | 0.007 | 0.03 | |
| AP2A2 | SP1 | 0.007 | 0.122 | |
| NECAP2 | CLTCL1 | 0.007 | 0.078 | |
| AP1M2 | COMT | 0.007 | 0.084 | |
| AP1M2 | CLTC | 0.007 | 0.136325 | |
| PAAT | AP1M2 | 0.007 | 0.078 | |
| AP2B1 | GKN1 | 0.006 | ||
| KIF13A | GAK | 0.006 | ||
| SEC24B | GULP1 | 0.006 | 0.09 | |
| RUNDC3A | SEC16A | 0.006 | ||
| SEC24B | AP1G2 | 0.006 | 0.018 | |
| STAMBP | COMT | 0.006 | 0.05 | |
| ITSN2 | SEC16A | 0.006 | ||
| NECAP2 | AFTPH | 0.006 | 0.046 | |
| AFTPH | ZNF106 | 0.006 | 0.05 | |
| KIF13A | WNK1 | 0.006 | ||
| WNK1 | GULP1 | 0.006 | 0.07 | |
| SYNRG | GULP1 | 0.006 | 0.09 | |
| AP1S2 | WNK1 | 0.006 | 0.056 | |
| KIF13A | SMAP2 | 0.006 | ||
| NECAP2 | ZNF106 | 0.006 | 0.04 | |
| SEC24B | HEATR5B | 0.006 | 0.146 | |
| REPS2 | CLTC | 0.006 | 0.242 | |
| ITSN1 | SMAP2 | 0.006 | ||
| AP2S1 | SEC24B | 0.006 | 0.122 | |
| TNRC6A | REPS2 | 0.006 | 0.102 | |
| SYNJ1 | SP1 | 0.006 | 0.038 | |
| AP1B1 | SP1 | 0.006 | 0.052 | |
| ITSN1 | SP1 | 0.006 | ||
| SP1 | REPS1 | 0.006 | 0.052 | |
| GAK | COMT | 0.005 | 0.03 | |
| MEA1 | CLTCL1 | 0.005 | 0.08 | |
| ITSN2 | ZNF106 | 0.005 | 0.106 | |
| REPS2 | AFTPH | 0.005 | 0.21 | |
| AP1S2 | GAK | 0.005 | 0.13 | |
| HEATR5B | SMAP2 | 0.005 | 0.042 | |
| HEATR5B | GAK | 0.005 | 0.192 | |
| TNRC6A | AP1G2 | 0.005 | 0.056 | |
| SEC24B | REPS2 | 0.005 | 0.148 | |
| DNAJC6 | COMT | 0.005 | 0.228 | |
| MEA1 | SEC16A | 0.005 | ||
| REPS2 | SEC16A | 0.005 | ||
| TNRC6A | KIF13A | 0.005 | ||
| AP1S2 | SEC16A | 0.005 | ||
| EPS15L1 | ZNF106 | 0.004 | 0.122 | |
| EPS15L1 | CLTCL1 | 0.004 | 0.312 | |
| CCDC32 | COMT | 0.004 | 0.032 | |
| NECAP2 | STAMBP | 0.004 | 0.164 | |
| NECAP2 | WNK1 | 0.004 | 0.02 | |
| EPS15L1 | PIK3C2A | 0.004 | 0.066 | |
| EPS15L1 | CLTC | 0.004 | 0.624 | |
| AP1M2 | CLTCL1 | 0.004 | 0.106 | |
| ITSN1 | CLTCL1 | 0.004 | ||
| CCDC32 | CLTC | 0.004 | 0.222 | |
| AP2A2 | TNRC6A | 0.004 | 0.216597222222 | |
| CCDC32 | SEC16A | 0.004 | ||
| SEC16A | COMT | 0.004 | ||
| AP2M1 | SP1 | 0.004 | 0.038 | |
| NECAP2 | GAK | 0.004 | 0.086 | |
| NECAP2 | SMAP2 | 0.004 | 0.054 | |
| ITSN1 | PAAT | 0.003 | ||
| EPS15L1 | WNK1 | 0.003 | 0.176 | |
| CCDC32 | SEC24B | 0.003 | 0.126 | |
| GKN1 | SEC16A | 0.003 | ||
| EPS15L1 | SP1 | 0.003 | 0.074 | |
| ITSN2 | CLINT1 | 0.003 | 0.074 | |
| ITSN1 | ZNF106 | 0.003 | ||
| EPS15L1 | STAMBPL1 | 0.003 | 0.06 | |
| EPS15L1 | GAK | 0.003 | 0.166 | |
| EPS15L1 | PAAT | 0.003 | 0.164 | |
| SEC24B | KIF13A | 0.003 | ||
| AAGAB | SEC16A | 0.003 | ||
| EPN1 | EPS15L1 | 0.003 | 0.288 | |
| SEC24B | AP1M2 | 0.002 | 0.182533333333 | |
| EPS15L1 | HIP1 | 0.002 | 0.07 | |
| NECAP2 | TNRC6A | 0.002 | 0.098 | |
| AP2A2 | WNK1 | 0.002 | 0.242 | |
| AP1S2 | TNRC6A | 0.002 | 0.074 | |
| CLINT1 | COMT | 0.002 | 0.174 | |
| NECAP2 | CLTC | 0.002 | 0.202 | |
| NECAP2 | SEC24B | 0.002 | 0.1 | |
| NECAP2 | SEC16A | 0.002 | ||
| KIF13A | CLTC | 0.002 | ||
| SEC24B | COMT | 0.001 | 0.084 | |
| EPS15L1 | SEC16A | 0.001 | ||
| TNRC6A | AP1M2 | 0.001 | 0.062 | |
| ITSN1 | CLTC | 0.001 | ||
| ITSN2 | CLTC | 0.0 | 0.182 |
Related Complexes