hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12918.1
Complex Portal: CPX-14264
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PIK3C2A | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha) | 5 | UniProt NCBI |
| HEATR5B | HEAT repeat-containing protein 5B | 5 | UniProt NCBI |
| CLTC | Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17) | 5 | UniProt NCBI |
| BMP2K | BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1) | 5 | UniProt NCBI |
| AFTPH | Aftiphilin | 5 | UniProt NCBI |
| MEA1 | Male-enhanced antigen 1 (MEA-1) | 3 | UniProt NCBI |
| HIP1 | Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I) | 5 | UniProt NCBI |
| AP2M1 | AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein) | 5 | UniProt NCBI |
| RALBP1 | RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (EC 7.6.2.2, EC 7.6.2.3) (Ral-interacting protein 1) | 5 | UniProt NCBI |
| SEC16A | Protein transport protein Sec16A (SEC16 homolog A) (p250) | 5 | UniProt NCBI |
| NUMB | Protein numb homolog (h-Numb) (Protein S171) | 5 | UniProt NCBI |
| AP1G1 | AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) | 5 | UniProt NCBI |
| RSKR | Ribosomal protein S6 kinase related | 1 | UniProt NCBI |
| WNK1 | Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1) | 5 | UniProt NCBI |
| AP2S1 | AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin) | 5 | UniProt NCBI |
| REPS1 | RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) | 5 | UniProt NCBI |
| KIF13A | Kinesin-like protein KIF13A (Kinesin-like protein RBKIN) | 5 | UniProt NCBI |
| GKN1 | Gastrokine-1 (18 kDa antrum mucosa protein) (AMP-18) (Protein CA11) | 5 | UniProt NCBI |
| CLINT1 | Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR) | 5 | UniProt NCBI |
| GULP1 | PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP) | 5 | UniProt NCBI |
| AP2A2 | AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Huntingtin yeast partner J) (Huntingtin-interacting protein 9) (HIP-9) (Huntingtin-interacting protein J) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) | 5 | UniProt NCBI |
| AP1M1 | AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin) | 5 | UniProt NCBI |
| STAMBPL1 | AMSH-like protease (AMSH-LP) (EC 3.4.19.-) (STAM-binding protein-like 1) | 5 | UniProt NCBI |
| ITSN2 | Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein) | 5 | UniProt NCBI |
| RUNDC3B | RUN domain-containing protein 3B (Rap2-binding protein 9) (Rap2-interacting protein 9) (RPIP-9) | 4 | UniProt NCBI |
| SEC24B | Protein transport protein Sec24B (SEC24-related protein B) | 5 | UniProt NCBI |
| TNRC6A | Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa) | 5 | UniProt NCBI |
| GAK | Cyclin-G-associated kinase (EC 2.7.11.1) | 5 | UniProt NCBI |
| AP1S3 | AP-1 complex subunit sigma-3 (Adaptor protein complex AP-1 subunit sigma-1C) (Adaptor-related protein complex 1 subunit sigma-1C) (Clathrin assembly protein complex 1 sigma-1C small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Sigma 1C subunit of AP-1 clathrin) (Sigma-adaptin 1C) (Sigma1C-adaptin) | 5 | UniProt NCBI |
| AAGAB | Alpha- and gamma-adaptin-binding protein p34 | 5 | UniProt NCBI |
| STAMBP | STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase) | 5 | UniProt NCBI |
| DNAJC6 | Auxilin (EC 3.1.3.-) (DnaJ homolog subfamily C member 6) | 5 | UniProt NCBI |
| AAK1 | AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1) | 5 | UniProt NCBI |
| EPS15L1 | Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) | 5 | UniProt NCBI |
| SYNRG | Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin) | 5 | UniProt NCBI |
| EPS15 | Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p) | 5 | UniProt NCBI |
| SMAP2 | Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like) | 5 | UniProt NCBI |
| AP1S1 | AP-1 complex subunit sigma-1A (Adaptor protein complex AP-1 subunit sigma-1A) (Adaptor-related protein complex 1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin) | 5 | UniProt NCBI |
| REPS2 | RalBP1-associated Eps domain-containing protein 2 (Partner of RalBP1) (RalBP1-interacting protein 2) | 5 | UniProt NCBI |
| AP1B1 | AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) | 5 | UniProt NCBI |
| AP2B1 | AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) | 5 | UniProt NCBI |
| CCDC32 | Coiled-coil domain-containing protein 32 | 5 | UniProt NCBI |
| AP1S2 | AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin) | 5 | UniProt NCBI |
| EPN1 | Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1) | 5 | UniProt NCBI |
| SP1 | Transcription factor Sp1 | 5 | UniProt NCBI |
| AP1AR | AP-1 complex-associated regulatory protein (2c18) (Adaptor-related protein complex 1-associated regulatory protein) (Gamma-1-adaptin brefeldin A resistance protein) (GBAR) (Gamma-BAR) (Gamma-A1-adaptin and kinesin interactor) (Gadkin) | 5 | UniProt NCBI |
| CLTCL1 | Clathrin heavy chain 2 (Clathrin heavy chain on chromosome 22) (CLH-22) | 5 | UniProt NCBI |
| PAAT | ATPase PAAT (EC 3.6.1.-) (Protein associated with ABC transporters) (PAAT) | 5 | UniProt NCBI |
| RUNDC3A | RUN domain-containing protein 3A (Rap2-interacting protein 8) (RPIP-8) | 5 | UniProt NCBI |
| COMT | Catechol O-methyltransferase (EC 2.1.1.6) | 5 | UniProt NCBI |
| AP1G2 | AP-1 complex subunit gamma-like 2 (Gamma2-adaptin) (G2ad) | 5 | UniProt NCBI |
| DENND1A | DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn) (Protein FAM31A) | 5 | UniProt NCBI |
| AMPH | Amphiphysin | 5 | UniProt NCBI |
| AP1M2 | AP-1 complex subunit mu-2 (AP-mu chain family member mu1B) (Adaptor protein complex AP-1 subunit mu-2) (Adaptor-related protein complex 1 subunit mu-2) (Clathrin assembly protein complex 1 mu-2 medium chain 2) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Mu-adaptin 2) (Mu1B-adaptin) | 5 | UniProt NCBI |
| NECAP2 | Adaptin ear-binding coat-associated protein 2 (NECAP endocytosis-associated protein 2) (NECAP-2) | 4 | UniProt NCBI |
| FCHO2 | F-BAR domain only protein 2 | 5 | UniProt NCBI |
| ZNF106 | Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) | 5 | UniProt NCBI |
| SYNJ1 | Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) | 5 | UniProt NCBI |
| ITSN1 | Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17) | 5 | UniProt NCBI |
| AP2A1 | AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit) | 5 | UniProt NCBI |
| NECAP1 | Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1) | 4 | UniProt NCBI |
| STON2 | Stonin-2 (Stoned B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030118 | 1.2905046117e-47 | 0.403225806452 | NECAP2 EPS15L1 AP1G2 AP1M2 AP1S3 STON2 CLINT1 AP2A2 AP2B1 CLTC AP1B1 AP2S1 AP1M1 AP1S2 NECAP1 AP1S1 AFTPH EPS15 AP1G1 SYNRG AP2M1 CLTCL1 SYNJ1 AP2A1 EPN1 | clathrin coat |
| GO:0048475 | 1.99883618579e-38 | 0.41935483871 | SEC24B NECAP2 EPS15L1 AP1G2 AP1M2 AP1S3 STON2 CLINT1 AP2A2 AP2B1 CLTC AFTPH AP2S1 AP1M1 AP1S2 NECAP1 AP1S1 AP1B1 EPS15 AP1G1 SYNRG AP2M1 CLTCL1 SYNJ1 AP2A1 EPN1 | coated membrane |
| GO:0030117 | 1.99883618579e-38 | 0.41935483871 | SEC24B NECAP2 EPS15L1 AP1G2 AP1M2 AP1S3 STON2 CLINT1 AP2A2 AP2B1 CLTC AFTPH AP2S1 AP1M1 AP1S2 NECAP1 AP1S1 AP1B1 EPS15 AP1G1 SYNRG AP2M1 CLTCL1 SYNJ1 AP2A1 EPN1 | membrane coat |
| GO:0030125 | 5.60766267549e-38 | 0.322580645161 | AP1S1 AP1S2 NECAP1 AP1S3 AP1M2 AP2B1 EPN1 AFTPH AP1M1 CLINT1 AP1G1 AP2M1 AP1G2 SYNRG STON2 NECAP2 AP1B1 AP2S1 AP2A1 AP2A2 | clathrin vesicle coat |
| GO:0030136 | 5.48570271259e-36 | 0.451612903226 | PIK3C2A NECAP2 NUMB AP1G2 AAK1 AP1S3 STON2 CLINT1 AP2A2 AP2B1 CLTC AP1B1 AP2S1 AP1M1 AP1S2 NECAP1 AP1S1 AFTPH AP1G1 FCHO2 SYNRG DENND1A AP2M1 CLTCL1 HIP1 AP1M2 EPN1 AP2A1 | clathrin-coated vesicle |
| GO:0030135 | 6.37788692671e-34 | 0.483870967742 | SEC24B NUMB FCHO2 PIK3C2A SEC16A AP2A2 AAK1 AP1S3 STON2 CLINT1 AP1G2 AP2B1 CLTC AFTPH AP2S1 AP1M1 AP1S2 NECAP1 AP1S1 AP1B1 AP1G1 NECAP2 SYNRG DENND1A AP2M1 CLTCL1 HIP1 AP1M2 EPN1 AP2A1 | coated vesicle |
| REAC:R-HSA-199991 | 6.49095792261e-34 | 0.596774193548 | GAK SEC24B NECAP2 DNAJC6 FCHO2 ITSN2 SEC16A EPS15L1 AP2A2 AAK1 AP1S3 STON2 CLINT1 AP2M1 AP2B1 CLTC AP2S1 AP1M1 ITSN1 AP1S2 NECAP1 CLTCL1 AP1B1 EPS15 AP1G1 AMPH DENND1A REPS2 AP1S1 HIP1 EPN1 AP1M2 PIK3C2A AP1G2 SYNJ1 REPS1 AP2A1 | Membrane Trafficking |
| REAC:R-HSA-8856828 | 4.60434606925e-33 | 0.403225806452 | GAK NECAP2 PIK3C2A EPS15L1 AP2A2 ITSN2 AAK1 STON2 AP2M1 AP2B1 ITSN1 AP2S1 CLTC NECAP1 SYNJ1 EPS15 FCHO2 AMPH DNAJC6 REPS2 CLTCL1 HIP1 AP2A1 EPN1 REPS1 | Clathrin-mediated endocytosis |
| REAC:R-HSA-5653656 | 4.8898551429e-33 | 0.596774193548 | GAK SEC24B NECAP2 DNAJC6 FCHO2 ITSN2 SEC16A EPS15L1 AP2A2 AAK1 AP1S3 STON2 CLINT1 AP2M1 AP2B1 CLTC AP2S1 AP1M1 ITSN1 AP1S2 NECAP1 CLTCL1 AP1B1 EPS15 AP1G1 AMPH DENND1A REPS2 AP1S1 HIP1 EPN1 AP1M2 PIK3C2A AP1G2 SYNJ1 REPS1 AP2A1 | Vesicle-mediated transport |
| GO:0030131 | 1.01203235716e-32 | 0.258064516129 | AP1S1 AP1S2 AP1S3 AP1M2 AP2B1 AFTPH AP1M1 AP1G1 AP2M1 AP1G2 SYNRG STON2 AP1B1 AP2S1 AP2A1 AP2A2 | clathrin adaptor complex |
| GO:0030120 | 3.19699959993e-32 | 0.338709677419 | AP1S1 AP1S2 NECAP1 AP1S3 AP1B1 AP2B1 EPN1 AFTPH AP1M1 CLINT1 AP1G1 AP2M1 AP1G2 SYNRG STON2 NECAP2 SEC24B AP2S1 AP2A1 AP1M2 AP2A2 | vesicle coat |
| GO:0016192 | 3.77251252315e-31 | 0.709677419355 | GAK SEC24B NECAP2 DNAJC6 FCHO2 ITSN2 SEC16A RALBP1 AP2A2 AAK1 AP1S3 STON2 CLINT1 REPS2 AP2B1 CLTC AP1B1 AP2S1 AP1M1 ITSN1 CLTCL1 AP1S2 NECAP1 CCDC32 GULP1 EPS15L1 AP1G1 EPS15 AMPH HEATR5B DENND1A AP2M1 HIP1 AP1S1 BMP2K EPN1 AP1M2 PIK3C2A AP1G2 SYNJ1 REPS1 AP2A1 AP1AR KIF13A | vesicle-mediated transport |
| GO:0030665 | 3.5655759932e-29 | 0.354838709677 | NECAP2 AP1G2 AP1M2 AP1S3 CLINT1 AP2M1 AP2A2 AP2B1 CLTC AP1B1 AP2S1 AP1M1 AP1S2 AFTPH AP1G1 NECAP1 SYNRG DENND1A STON2 AP1S1 AP2A1 EPN1 | clathrin-coated vesicle membrane |
| GO:0030662 | 5.71946008267e-28 | 0.387096774194 | SEC24B NECAP2 SEC16A AP1G2 AP1M2 AP1S3 STON2 CLINT1 AP2A2 AP2B1 CLTC AFTPH AP2S1 AP1M1 AP1S2 AP1B1 AP1G1 NECAP1 SYNRG DENND1A AP2M1 AP1S1 AP2A1 EPN1 | coated vesicle membrane |
| GO:0006897 | 2.11159084371e-27 | 0.516129032258 | GAK DNAJC6 FCHO2 ITSN2 RALBP1 AP2A2 AAK1 STON2 CLINT1 AP2M1 AP2B1 CLTC AP2S1 ITSN1 CLTCL1 CCDC32 GULP1 EPS15 NECAP2 AMPH HEATR5B DENND1A REPS2 HIP1 AP1S1 BMP2K EPN1 AP2A1 PIK3C2A SYNJ1 REPS1 EPS15L1 | endocytosis |
| GO:0030119 | 2.5531846918e-25 | 0.258064516129 | AP1S1 AP1S2 AP1S3 AP1M2 AP2B1 AFTPH AP1M1 AP1G1 AP2M1 AP1G2 SYNRG STON2 AP1B1 AP2S1 AP2A1 AP2A2 | AP-type membrane coat adaptor complex |
| REAC:R-HSA-8856825 | 4.34049143212e-25 | 0.306451612903 | CLTCL1 AAK1 EPS15 NECAP1 STON2 EPN1 NECAP2 AP2A1 ITSN1 FCHO2 EPS15L1 ITSN2 REPS2 AP2M1 AP2B1 REPS1 AP2S1 AP2A2 CLTC | Cargo recognition for clathrin-mediated endocytosis |
| GO:0005905 | 3.89427881944e-24 | 0.258064516129 | CLTCL1 AAK1 SYNJ1 STON2 CCDC32 AP2A1 ITSN1 NECAP2 EPS15 FCHO2 AP2M1 AP2B1 EPS15L1 AP2S1 AP2A2 REPS1 | clathrin-coated pit |
| GO:0098657 | 1.1453008499e-23 | 0.516129032258 | GAK DNAJC6 FCHO2 ITSN2 RALBP1 AP2A2 AAK1 STON2 CLINT1 AP2M1 AP2B1 CLTC AP2S1 ITSN1 CLTCL1 CCDC32 GULP1 EPS15 NECAP2 AMPH HEATR5B DENND1A REPS2 HIP1 AP1S1 BMP2K EPN1 AP2A1 PIK3C2A SYNJ1 REPS1 EPS15L1 | import into cell |
| REAC:R-HSA-164938 | 1.1933413352e-21 | 0.193548387097 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 AP1M1 AP1G1 AP2M1 AP2B1 AP2A1 AP2S1 AP2A2 | Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| GO:0072583 | 1.21198156437e-21 | 0.241935483871 | AAK1 BMP2K STON2 CCDC32 AP2A1 ITSN1 ITSN2 FCHO2 AP2M1 AP2B1 CLTC AP2S1 DNAJC6 AP2A2 GAK | clathrin-dependent endocytosis |
| GO:0030130 | 1.87438080669e-21 | 0.177419354839 | AP1S1 AP1S3 AP1M2 AP1S2 AFTPH AP1G1 AP1G2 SYNRG AP1B1 AP2A1 AP1M1 | clathrin coat of trans-Golgi network vesicle |
| GO:0030121 | 4.40116128452e-20 | 0.161290322581 | AP1S1 AP1S3 AP1M2 AP1S2 AFTPH AP1G1 AP1G2 SYNRG AP1B1 AP1M1 | AP-1 adaptor complex |
| GO:0035615 | 5.64927645501e-20 | 0.177419354839 | AP1M2 HIP1 STON2 AP2A1 AP1G1 AP2M1 AP2A2 AP1G2 AP2B1 AP2S1 AP1M1 | clathrin adaptor activity |
| GO:0012510 | 5.64927645501e-20 | 0.177419354839 | AP1S1 AP1S3 AP1M2 AP1S2 AFTPH AP1G1 AP1G2 SYNRG AP1B1 AP2A1 AP1M1 | trans-Golgi network transport vesicle membrane |
| REAC:R-HSA-164952 | 6.92490759235e-20 | 0.193548387097 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 AP1M1 AP1G1 AP2M1 AP2B1 AP2A1 AP2S1 AP2A2 | The role of Nef in HIV-1 replication and disease pathogenesis |
| CORUM:144 | 1.14423926169e-19 | 0.145161290323 | AP1S2 AP1S3 AP1M2 AP1S1 AP1B1 AP1G1 AP1G2 AP1AR AP1M1 | Gamma-BAR-AP1 complex |
| GO:0140312 | 2.11169621526e-19 | 0.177419354839 | AP1M2 HIP1 STON2 AP2A1 AP1G1 AP2M1 AP2A2 AP1G2 AP2B1 AP2S1 AP1M1 | cargo adaptor activity |
| REAC:R-HSA-199992 | 7.80719533656e-18 | 0.225806451613 | AP1S1 NECAP1 GAK AP1M2 AP1S2 AP1B1 CLINT1 AP1G1 PIK3C2A AP1G2 CLTC DNAJC6 AP1M1 AP1S3 | trans-Golgi Network Vesicle Budding |
| GO:0006810 | 1.80727984689e-17 | 0.758064516129 | GAK AP1B1 SEC24B NECAP2 DNAJC6 FCHO2 ITSN2 SEC16A RALBP1 AP2A2 AAK1 AP1S3 STON2 CLINT1 REPS2 AP2B1 CLTC GULP1 AP2S1 AP1M1 ITSN1 CLTCL1 AP1S2 NECAP1 CCDC32 AFTPH EPS15L1 AP1G1 WNK1 SYNRG AMPH HEATR5B DENND1A AP2M1 HIP1 AP1S1 EPS15 BMP2K EPN1 AP1M2 PIK3C2A AP1G2 SYNJ1 REPS1 AP2A1 AP1AR KIF13A | transport |
| CORUM:36 | 3.09516720287e-17 | 0.129032258065 | AP1S2 AP1S3 AP1M2 AP1S1 AP1B1 AP1G1 AP1G2 AP1M1 | AP1 adaptor complex |
| GO:0006898 | 7.71740695119e-17 | 0.306451612903 | CLTCL1 AAK1 EPS15 HIP1 STON2 AP1S1 AP2A1 CCDC32 GAK ITSN2 FCHO2 AP2M1 ITSN1 AP2B1 CLTC AP2S1 DNAJC6 AP2A2 BMP2K | receptor-mediated endocytosis |
| GO:0097708 | 2.7312908019e-16 | 0.612903225806 | AP1B1 SEC24B NECAP2 NUMB SEC16A AP2A2 ITSN2 AAK1 AP1S3 STON2 CLINT1 AP1G2 AP2B1 CLTC STAMBP AP2S1 AP1M1 ITSN1 AP1S2 NECAP1 CLTCL1 AFTPH AP1G1 FCHO2 SYNRG AMPH KIF13A DENND1A AP2M1 AP1S1 HIP1 EPN1 STAMBPL1 PIK3C2A AP1M2 AP2A1 AP1AR HEATR5B | intracellular vesicle |
| GO:0051234 | 9.72567744049e-16 | 0.758064516129 | GAK AP1B1 SEC24B NECAP2 DNAJC6 FCHO2 ITSN2 SEC16A RALBP1 AP2A2 AAK1 AP1S3 STON2 CLINT1 REPS2 AP2B1 CLTC GULP1 AP2S1 AP1M1 ITSN1 CLTCL1 AP1S2 NECAP1 CCDC32 AFTPH EPS15L1 AP1G1 WNK1 SYNRG AMPH HEATR5B DENND1A AP2M1 HIP1 AP1S1 EPS15 BMP2K EPN1 AP1M2 PIK3C2A AP1G2 SYNJ1 REPS1 AP2A1 AP1AR KIF13A | establishment of localization |
| REAC:R-HSA-432722 | 1.25430961614e-15 | 0.193548387097 | AP1S1 NECAP1 GAK AP1M2 AP1S2 AP1B1 CLINT1 AP1G1 PIK3C2A DNAJC6 AP1M1 AP1S3 | Golgi Associated Vesicle Biogenesis |
| GO:0030132 | 2.64230758795e-15 | 0.145161290323 | SYNJ1 STON2 AP2A1 EPS15 AP2A2 AP2B1 EPS15L1 AP2S1 AP2M1 | clathrin coat of coated pit |
| GO:0030140 | 3.18643976008e-15 | 0.177419354839 | AP1S1 AP1S3 AP1M2 AP1S2 AFTPH AP1G1 AP1G2 SYNRG AP1B1 AP2A1 AP1M1 | trans-Golgi network transport vesicle |
| REAC:R-HSA-2132295 | 1.60695696169e-14 | 0.225806451613 | AP1S1 AP1S3 AP1M2 AP1S2 SEC24B AP1G1 AP2M1 AP2A2 AP2B1 CLTC AP1B1 AP2S1 AP2A1 AP1M1 | MHC class II antigen presentation |
| REAC:R-HSA-432720 | 2.8862099606e-14 | 0.161290322581 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 DNAJC6 AP1G1 AP1G2 CLTC AP1M1 | Lysosome Vesicle Biogenesis |
| GO:0031410 | 3.56711147095e-14 | 0.58064516129 | AP1M2 SEC24B NECAP2 NUMB SEC16A AP2A2 AAK1 AP1S3 STON2 CLINT1 AP1G2 AP2B1 CLTC STAMBP AP2S1 AP1M1 AP1S2 NECAP1 CLTCL1 AP1B1 AP1G1 FCHO2 SYNRG AMPH KIF13A AFTPH DENND1A AP2M1 AP1S1 HIP1 EPN1 STAMBPL1 PIK3C2A AP2A1 AP1AR HEATR5B | cytoplasmic vesicle |
| GO:0051179 | 7.00426401281e-14 | 0.774193548387 | GAK AP1B1 SEC24B NECAP2 DNAJC6 FCHO2 NUMB SEC16A RALBP1 AP2A2 ITSN2 AAK1 AP1S3 STON2 CLINT1 REPS2 AP2B1 CLTC GULP1 AP2S1 AP1M1 ITSN1 CLTCL1 AP1S2 NECAP1 CCDC32 AFTPH EPS15L1 AP1G1 WNK1 SYNRG AMPH KIF13A DENND1A AP2M1 HIP1 AP1S1 EPS15 BMP2K EPN1 AP1M2 PIK3C2A AP1G2 SYNJ1 REPS1 AP2A1 AP1AR HEATR5B | localization |
| GO:0012506 | 5.30361208447e-13 | 0.41935483871 | SEC24B NECAP2 SEC16A AP1G2 AP1M2 AP1S3 STON2 CLINT1 AP2A2 AP2B1 CLTC AFTPH AP2S1 AP1M1 AP1S2 SYNJ1 AP1B1 AP1G1 NECAP1 SYNRG KIF13A DENND1A AP2M1 AP1S1 AP2A1 EPN1 | vesicle membrane |
| REAC:R-HSA-164940 | 7.90366681766e-13 | 0.112903225806 | AP1S2 AP1S3 AP1M2 AP1S1 AP1B1 AP1G1 AP1M1 | Nef mediated downregulation of MHC class I complex cell surface expression |
| GO:0030660 | 1.4262129012e-12 | 0.177419354839 | AP1S1 AP1S3 AP1M2 AP1S2 AFTPH AP1G1 AP1G2 SYNRG AP1B1 AP2A1 AP1M1 | Golgi-associated vesicle membrane |
| GO:0140238 | 1.4262129012e-12 | 0.177419354839 | SYNJ1 GAK STON2 DNAJC6 FCHO2 ITSN2 AP2B1 AMPH ITSN1 AP2S1 AP2M1 | presynaptic endocytosis |
| GO:0048488 | 1.4262129012e-12 | 0.177419354839 | SYNJ1 GAK STON2 DNAJC6 FCHO2 ITSN2 AP2B1 AMPH ITSN1 AP2S1 AP2M1 | synaptic vesicle endocytosis |
| GO:0051649 | 1.79692677443e-12 | 0.516129032258 | GAK SEC24B DNAJC6 FCHO2 AMPH SEC16A EPS15L1 AP2A2 AP1M2 STON2 AP2M1 AP2B1 CLTC AP2S1 AP1M1 ITSN1 SYNJ1 AFTPH EPS15 AP1G1 SYNRG KIF13A DENND1A REPS2 WNK1 CLTCL1 AP2A1 ITSN2 AP1G2 REPS1 AP1AR HEATR5B | establishment of localization in cell |
| GO:0098796 | 4.70413519538e-12 | 0.435483870968 | SEC24B NECAP2 PIK3C2A EPS15L1 AP1G2 AP1M2 AP1S3 STON2 CLINT1 AP2A2 AP2B1 CLTC AFTPH AP2S1 AP1M1 AP1S2 NECAP1 AP1S1 AP1B1 EPS15 AP1G1 SYNRG AP2M1 CLTCL1 SYNJ1 AP2A1 EPN1 | membrane protein complex |
| GO:0030659 | 4.83462222465e-12 | 0.403225806452 | SEC24B NECAP2 SEC16A AP1G2 AP1M2 AP1S3 STON2 CLINT1 AP2A2 AP2B1 CLTC AFTPH AP2S1 AP1M1 AP1S2 AP1B1 AP1G1 NECAP1 SYNRG KIF13A DENND1A AP2M1 AP1S1 AP2A1 EPN1 | cytoplasmic vesicle membrane |
| GO:0036465 | 1.30664241819e-11 | 0.177419354839 | SYNJ1 GAK STON2 DNAJC6 FCHO2 ITSN2 AP2B1 AMPH ITSN1 AP2S1 AP2M1 | synaptic vesicle recycling |
| GO:0099003 | 2.86657616564e-11 | 0.209677419355 | SYNJ1 GAK STON2 AP2A1 DNAJC6 FCHO2 ITSN2 AP2B1 AMPH ITSN1 AP2S1 AP2A2 AP2M1 | vesicle-mediated transport in synapse |
| GO:0031982 | 4.40540209396e-11 | 0.677419354839 | GAK AP1B1 STAMBP DNAJC6 FCHO2 NUMB SEC16A AP2A2 ITSN2 AAK1 AP1S3 STON2 CLINT1 AP1G2 AP2B1 CLTC SEC24B AP2S1 AP1M1 ITSN1 AP1S2 NECAP1 CLTCL1 AFTPH AP1G1 NECAP2 SYNRG AMPH KIF13A DENND1A AP2M1 COMT AP1S1 HIP1 EPN1 STAMBPL1 PIK3C2A AP1M2 SYNJ1 AP2A1 AP1AR HEATR5B | vesicle |
| KEGG:04144 | 4.76558362667e-11 | 0.225806451613 | CLTCL1 EPS15 EPN1 STAMBP DNAJC6 AP2M1 AP2B1 AMPH CLTC SMAP2 AP2A1 AP2S1 AP2A2 EPS15L1 | Endocytosis |
| REAC:R-HSA-162909 | 5.14113233686e-11 | 0.193548387097 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 AP1M1 AP1G1 AP2M1 AP2B1 AP2A1 AP2S1 AP2A2 | Host Interactions of HIV factors |
| GO:0030276 | 5.83754736728e-11 | 0.161290322581 | CLTCL1 GAK EPN1 AFTPH CLINT1 PIK3C2A AP2B1 CLTC DNAJC6 HIP1 | clathrin binding |
| GO:0030658 | 6.65345068489e-11 | 0.209677419355 | AP1S1 AP1S2 AP1S3 AP1B1 SYNRG SEC24B AP1G1 AP1M2 AP1G2 SEC16A AFTPH AP2A1 AP1M1 | transport vesicle membrane |
| GO:0051641 | 7.63601881842e-11 | 0.612903225806 | GAK SEC24B DNAJC6 FCHO2 AMPH SEC16A EPS15L1 AP2A2 AAK1 AP1S3 STON2 NUMB REPS2 AP2B1 CLTC AP1B1 AP2S1 AP1M1 ITSN1 CLTCL1 AFTPH AP1G1 WNK1 SYNRG KIF13A DENND1A AP2M1 AP1S1 EPS15 HIP1 AP1M2 ITSN2 AP1G2 SYNJ1 REPS1 AP2A1 AP1AR HEATR5B | cellular localization |
| WP:WP437 | 1.02730581237e-10 | 0.193548387097 | SYNJ1 EPN1 STAMBP EPS15 REPS2 AP2B1 EPS15L1 SP1 AP2S1 AP2A1 AP2M1 RALBP1 | EGF EGFR signaling pathway |
| GO:0005798 | 2.37241786867e-10 | 0.177419354839 | AP1S1 AP1S3 AP1M2 AP1S2 AFTPH AP1G1 AP1G2 SYNRG AP1B1 AP2A1 AP1M1 | Golgi-associated vesicle |
| GO:0030133 | 2.55468303139e-10 | 0.258064516129 | AP1S1 AP1S2 AP1S3 AP1B1 SYNRG SEC24B AP1G1 AP1M2 AP1G2 SEC16A AMPH STON2 AFTPH AP1AR AP2A1 AP1M1 | transport vesicle |
| GO:0048268 | 1.46600844858e-09 | 0.112903225806 | GAK EPS15 FCHO2 PIK3C2A CLTC AP2S1 HIP1 | clathrin coat assembly |
| REAC:R-HSA-177504 | 1.57208366829e-09 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | Retrograde neurotrophin signalling |
| REAC:R-HSA-5140745 | 2.90999175181e-09 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | WNT5A-dependent internalization of FZD2, FZD5 and ROR2 |
| GO:0030128 | 6.32339020868e-09 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 AP2S1 AP2A2 STON2 | clathrin coat of endocytic vesicle |
| GO:0030122 | 6.32339020868e-09 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 AP2S1 AP2A2 STON2 | AP-2 adaptor complex |
| KEGG:04142 | 7.16926802642e-09 | 0.161290322581 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 AP1G1 AP1G2 CLTC AP1M1 CLTCL1 | Lysosome |
| REAC:R-HSA-5099900 | 8.43179763981e-09 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | WNT5A-dependent internalization of FZD4 |
| REAC:R-HSA-182218 | 9.27994422617e-09 | 0.0806451612903 | AP2S1 AP2A1 AP2M1 AP2B1 AP2A2 | Nef Mediated CD8 Down-regulation |
| REAC:R-HSA-8866427 | 1.34465535879e-08 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | VLDLR internalisation and degradation |
| GO:0012505 | 2.02002256785e-08 | 0.661290322581 | GAK AP1B1 STAMBP NECAP2 FCHO2 EPN1 SEC16A EPS15L1 GKN1 AP2A2 AAK1 AP1S3 STON2 CLINT1 AP1G2 AP2B1 CLTC SEC24B AP2S1 AP1M1 ITSN1 AP1S2 CCDC32 AFTPH AP1G1 EPS15 SYNRG AMPH KIF13A AP2M1 AP1S1 HIP1 STAMBPL1 TNRC6A PIK3C2A AP1M2 SYNJ1 REPS1 AP2A1 AP1AR CLTCL1 | endomembrane system |
| GO:0099504 | 2.88657315169e-08 | 0.177419354839 | SYNJ1 GAK STON2 DNAJC6 FCHO2 ITSN2 AP2B1 AMPH ITSN1 AP2S1 AP2M1 | synaptic vesicle cycle |
| REAC:R-HSA-8964038 | 3.0967074637e-08 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | LDL clearance |
| REAC:R-HSA-162906 | 4.49367021877e-08 | 0.193548387097 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 AP1M1 AP1G1 AP2M1 AP2B1 AP2A1 AP2S1 AP2A2 | HIV Infection |
| REAC:R-HSA-167590 | 5.53182339344e-08 | 0.0806451612903 | AP2S1 AP2A1 AP2M1 AP2B1 AP2A2 | Nef Mediated CD4 Down-regulation |
| WP:WP2267 | 6.86899444874e-08 | 0.112903225806 | CLTCL1 AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | Synaptic vesicle pathway |
| KEGG:04961 | 7.5275903163e-08 | 0.112903225806 | CLTCL1 AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | Endocrine and other factor-regulated calcium reabsorption |
| GO:0005829 | 9.51043663284e-08 | 0.741935483871 | GAK AP1B1 SEC24B DNAJC6 FCHO2 ITSN2 SEC16A RALBP1 ZNF106 AP2A2 AAK1 AP1S3 STON2 AAGAB CLINT1 REPS2 AP2B1 CLTC TNRC6A AP2S1 AP1M1 ITSN1 AP1S2 NECAP1 CLTCL1 AFTPH AP1G1 WNK1 AMPH HEATR5B DENND1A AP2M1 COMT AP1S1 EPS15 HIP1 EPN1 STAMBP STAMBPL1 PIK3C2A AP1M2 SYNJ1 REPS1 AP2A1 SMAP2 EPS15L1 | cytosol |
| CORUM:7476 | 1.38475185333e-07 | 0.0645161290323 | AP1G2 AP1S1 AP1M1 AP1B1 | AP1B1-AP1G2-AP1M-1AP1S1 complex |
| CORUM:247 | 1.38475185333e-07 | 0.0645161290323 | EPN1 AP2A1 RALBP1 NUMB | RalBP1-CCNB1-AP2A-NUMB-EPN1 complex |
| GO:0032588 | 2.17450664439e-07 | 0.161290322581 | AP1S1 AP1S3 AP1M2 AP1S2 AFTPH AP1G1 CLTC AP1B1 AP1M1 KIF13A | trans-Golgi network membrane |
| REAC:R-HSA-3928665 | 2.25603554349e-07 | 0.112903225806 | CLTCL1 AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | EPH-ephrin mediated repulsion of cells |
| REAC:R-HSA-437239 | 3.13040861822e-07 | 0.112903225806 | AP2A1 NUMB AP2M1 AP2B1 CLTC AP2S1 AP2A2 | Recycling pathway of L1 |
| KEGG:04721 | 4.42840370244e-07 | 0.112903225806 | CLTCL1 AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | Synaptic vesicle cycle |
| REAC:R-HSA-2682334 | 6.99546104879e-07 | 0.129032258065 | CLTCL1 AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 ITSN1 | EPH-Ephrin signaling |
| GO:0140239 | 1.21567269363e-06 | 0.0806451612903 | AP2S1 AP2A1 AP2M1 AP2B1 AP2A2 | postsynaptic endocytosis |
| GO:0098884 | 1.21567269363e-06 | 0.0806451612903 | AP2S1 AP2A1 AP2M1 AP2B1 AP2A2 | postsynaptic neurotransmitter receptor internalization |
| REAC:R-HSA-8964043 | 1.44358474823e-06 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | Plasma lipoprotein clearance |
| GO:0005768 | 2.53608822808e-06 | 0.306451612903 | CLTCL1 AP1S1 AP1S3 AP1B1 AP1S2 EPN1 STAMBPL1 AP1M1 CLINT1 AP1G1 AP2B1 AP1AR KIF13A STAMBP AP2S1 AP2A1 AP2A2 AP2M1 CLTC | endosome |
| GO:1903232 | 4.05668677745e-06 | 0.0967741935484 | AP1S2 AP1S3 AP1S1 AP1B1 AP1G1 AP1M1 | melanosome assembly |
| GO:0036020 | 4.05668677745e-06 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | endolysosome membrane |
| GO:0005802 | 4.76160498423e-06 | 0.193548387097 | CLTCL1 AP1S1 AP1S3 AP1M2 AP1S2 AFTPH PIK3C2A AP1G1 KIF13A AP1B1 AP1M1 CLTC | trans-Golgi network |
| WP:WP4159 | 6.41336950862e-06 | 0.0806451612903 | AP2S1 AP2A1 AP2M1 AP2B1 AP2A2 | GABA receptor signaling |
| GO:0048753 | 6.61026517707e-06 | 0.112903225806 | AP1S1 AP1S3 AP1S2 AP1B1 AP1G1 KIF13A AP1M1 | pigment granule organization |
| GO:0032438 | 6.61026517707e-06 | 0.112903225806 | AP1S1 AP1S3 AP1S2 AP1B1 AP1G1 KIF13A AP1M1 | melanosome organization |
| REAC:R-HSA-9824446 | 9.10044750614e-06 | 0.258064516129 | AP1S1 AP1S3 AP1M2 AP1S2 SEC24B AP1G1 AP2M1 AP2A2 SP1 AP2B1 CLTC AP1B1 AP2S1 AP2A1 AP1M1 COMT | Viral Infection Pathways |
| GO:0046907 | 1.04462285938e-05 | 0.354838709677 | GAK SEC24B SEC16A EPS15L1 AP1G2 ITSN1 AP1M1 CLTC AFTPH EPS15 AP1G1 WNK1 SYNRG KIF13A DENND1A REPS2 CLTCL1 AP2A1 ITSN2 REPS1 AP1AR HEATR5B | intracellular transport |
| GO:0060155 | 1.17415212988e-05 | 0.0967741935484 | AP1S2 AP1S3 AP1S1 AP1B1 AP1G1 AP1M1 | platelet dense granule organization |
| GO:0098588 | 1.23886738176e-05 | 0.403225806452 | SEC24B NECAP2 SEC16A AP1G2 AP1M2 AP1S3 STON2 CLINT1 AP2A2 AP2B1 CLTC AFTPH AP2S1 AP1M1 AP1S2 AP1B1 AP1G1 NECAP1 SYNRG KIF13A DENND1A AP2M1 AP1S1 AP2A1 EPN1 | bounding membrane of organelle |
| GO:0110010 | 1.46783696453e-05 | 0.0645161290323 | AP1S1 AP1G1 AP1M2 AP1B1 | basolateral protein secretion |
| GO:0005794 | 2.35626101599e-05 | 0.354838709677 | GAK SEC16A GKN1 AP1G2 AP1M2 AP1S3 CLINT1 CLTC AFTPH AP1M1 AP1S2 AP1S1 AP1B1 AP1G1 SYNRG KIF13A CLTCL1 HIP1 AP2A1 TNRC6A PIK3C2A AP1AR | Golgi apparatus |
| REAC:R-HSA-5663205 | 2.55256831213e-05 | 0.274193548387 | AP1S1 EPS15 AP1S3 AP1M2 AP1S2 SEC24B AP1G1 AP2M1 AP2A2 SP1 AP2B1 CLTC AP1B1 AP2S1 AP2A1 AP1M1 COMT | Infectious disease |
| GO:0098791 | 3.0641828416e-05 | 0.193548387097 | CLTCL1 AP1S1 AP1S3 AP1M2 AP1S2 AFTPH PIK3C2A AP1G1 KIF13A AP1B1 AP1M1 CLTC | Golgi apparatus subcompartment |
| GO:0045334 | 3.56026726891e-05 | 0.129032258065 | CLTCL1 STON2 AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | clathrin-coated endocytic vesicle |
| GO:0098852 | 4.14570557557e-05 | 0.209677419355 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 AP1G1 AP2M1 AP2A2 AP2B1 CLTC AP2A1 AP2S1 AP1M1 | lytic vacuole membrane |
| GO:0005765 | 4.14570557557e-05 | 0.209677419355 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 AP1G1 AP2M1 AP2A2 AP2B1 CLTC AP2A1 AP2S1 AP1M1 | lysosomal membrane |
| GO:0016020 | 4.24274203099e-05 | 0.774193548387 | GAK AP1B1 SEC24B NECAP2 FCHO2 NUMB SEC16A RALBP1 ZNF106 AP2A2 ITSN2 AAK1 AP1S3 STON2 CLINT1 REPS2 AP2B1 CLTC STAMBP AP2S1 AP1M1 ITSN1 CLTCL1 AP1S2 NECAP1 CCDC32 AFTPH EPS15L1 AP1G1 WNK1 SYNRG AMPH KIF13A DENND1A AP2M1 COMT AP1S1 EPS15 HIP1 EPN1 STAMBPL1 PIK3C2A AP1M2 AP1G2 SYNJ1 REPS1 AP2A1 HEATR5B | membrane |
| GO:0099590 | 4.51078517047e-05 | 0.0806451612903 | AP2S1 AP2A1 AP2M1 AP2B1 AP2A2 | neurotransmitter receptor internalization |
| GO:0036019 | 6.27978277974e-05 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | endolysosome |
| REAC:R-HSA-174824 | 7.27347791401e-05 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | Plasma lipoprotein assembly, remodeling, and clearance |
| REAC:R-HSA-373760 | 8.97740154343e-05 | 0.112903225806 | AP2A1 NUMB AP2M1 AP2B1 CLTC AP2S1 AP2A2 | L1CAM interactions |
| GO:0005774 | 0.000105417260932 | 0.209677419355 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 AP1G1 AP2M1 AP2A2 AP2B1 CLTC AP2A1 AP2S1 AP1M1 | vacuolar membrane |
| KEGG:05170 | 0.00011517568212 | 0.129032258065 | AP1S2 AP1S3 AP1M2 AP1S1 AP1B1 AP1G1 AP1G2 AP1M1 | Human immunodeficiency virus 1 infection |
| GO:0033059 | 0.000150923696882 | 0.112903225806 | AP1S1 AP1S3 AP1S2 AP1B1 AP1G1 KIF13A AP1M1 | cellular pigmentation |
| KEGG:05016 | 0.000152800164513 | 0.145161290323 | CLTCL1 HIP1 AP2A1 AP2M1 AP2B1 CLTC SP1 AP2S1 AP2A2 | Huntington disease |
| HPA:0100212 | 0.000156136016549 | 0.41935483871 | GAK SEC24B DNAJC6 ITSN2 EPS15L1 AP2A2 AAK1 AAGAB CLINT1 AP1G2 AP2B1 CLTC GULP1 SYNJ1 AP1B1 EPS15 AP1G1 SYNRG AMPH HIP1 BMP2K AP2A1 TNRC6A EPN1 REPS1 RALBP1 | cerebral cortex; neuropil[>=Medium] |
| REAC:R-HSA-1280218 | 0.000204013916042 | 0.225806451613 | AP1S1 AP1S3 AP1M2 AP1S2 SEC24B AP1G1 AP2M1 AP2A2 AP2B1 CLTC AP1B1 AP2S1 AP2A1 AP1M1 | Adaptive Immune System |
| GO:0030669 | 0.000282532156216 | 0.112903225806 | STON2 AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | clathrin-coated endocytic vesicle membrane |
| GO:0006892 | 0.000299418323379 | 0.129032258065 | GAK AP2A1 EPS15 AP1G1 SEC16A KIF13A AP1AR AP1G2 | post-Golgi vesicle-mediated transport |
| GO:0033363 | 0.0005648540015 | 0.0967741935484 | AP1S2 AP1S3 AP1S1 AP1B1 AP1G1 AP1M1 | secretory granule organization |
| REAC:R-HSA-9679191 | 0.000585252911825 | 0.0967741935484 | COMT AP2A1 AP2A2 AP2B1 AP2S1 AP2M1 | Potential therapeutics for SARS |
| REAC:R-HSA-3858494 | 0.000634137782832 | 0.112903225806 | TNRC6A AP2M1 AP2B1 CLTC AP2A1 AP2S1 AP2A2 | Beta-catenin independent WNT signaling |
| HPA:0100211 | 0.000852985276233 | 0.58064516129 | GAK AP1B1 SEC24B DNAJC6 CLINT1 EPS15L1 AP2A2 AAK1 AP1S3 AAGAB NUMB AP1G2 AP2B1 CLTC TNRC6A MEA1 SYNJ1 GULP1 AP1G1 WNK1 SYNRG AMPH AP1AR STON2 HIP1 AP1S1 EPS15 COMT BMP2K EPN1 AP2A1 ITSN2 REPS1 SP1 SMAP2 RALBP1 | cerebral cortex; neuropil[>=Low] |
| REAC:R-HSA-4086400 | 0.000874550287482 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | PCP/CE pathway |
| WP:WP4549 | 0.000952730527894 | 0.0967741935484 | CLTCL1 AP2A1 AP2B1 CLTC AP2S1 AP2M1 | Fragile X syndrome |
| GO:0043473 | 0.0011418878617 | 0.112903225806 | AP1S1 AP1S3 AP1S2 AP1B1 AP1G1 KIF13A AP1M1 | pigmentation |
| GO:0016050 | 0.00116308524383 | 0.177419354839 | AP1S1 EPS15 AP1S3 AP1S2 SEC24B AP1G1 AP2M1 SYNJ1 KIF13A AP1B1 AP1M1 | vesicle organization |
| REAC:R-HSA-187037 | 0.00127118422684 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | Signaling by NTRK1 (TRKA) |
| GO:0016482 | 0.00178484178507 | 0.129032258065 | CLTCL1 GAK AP2A1 EPS15 AP1G1 HEATR5B AP1AR CLTC | cytosolic transport |
| REAC:R-HSA-166520 | 0.00324427030102 | 0.0967741935484 | AP2A1 AP2M1 AP2B1 CLTC AP2S1 AP2A2 | Signaling by NTRKs |
| GO:0016197 | 0.00351358689412 | 0.161290322581 | CLTCL1 HEATR5B ITSN1 EPS15 REPS2 ITSN2 REPS1 DENND1A CLTC EPS15L1 | endosomal transport |
| REAC:R-HSA-196025 | 0.00446905937216 | 0.0483870967742 | CLTCL1 CLTC AP2M1 | Formation of annular gap junctions |
| TF:M11442 | 0.00560722353442 | 0.370967741935 | GAK NECAP2 PIK3C2A SEC16A PAAT AAK1 AFTPH AP2S1 AP1M1 AP1S2 MEA1 CCDC32 AP1B1 AP1G1 SYNRG HEATR5B AP2M1 COMT BMP2K TNRC6A EPN1 AP1AR SMAP2 | Factor: Net; motif: NACCGGAAGTN |
| REAC:R-HSA-190873 | 0.00594072219467 | 0.0483870967742 | CLTCL1 CLTC AP2M1 | Gap junction degradation |
| CORUM:3231 | 0.00835252416677 | 0.0322580645161 | EPS15 STON2 | Eps15-stonin2 complex |
| GO:0099072 | 0.00909687797123 | 0.0806451612903 | AP2S1 AP2A1 AP2M1 AP2B1 AP2A2 | regulation of postsynaptic membrane neurotransmitter receptor levels |
| REAC:R-HSA-1643685 | 0.0107866384717 | 0.290322580645 | AP1S1 EPS15 COMT HIP1 AP1M2 AP1S2 SEC24B AP1M1 AP1G1 AP2M1 SP1 AP2B1 CLTC AP1B1 AP2S1 AP2A1 AP2A2 AP1S3 | Disease |
| HPA:0250000 | 0.0134276164035 | 0.661290322581 | GAK AP1B1 SEC24B NECAP2 DNAJC6 FCHO2 NUMB SEC16A EPS15L1 AP2A2 AAK1 AP1S3 AAGAB CLINT1 PAAT AP2B1 CLTC TNRC6A RUNDC3A ITSN1 SYNJ1 AFTPH AP1G1 WNK1 SYNRG HEATR5B AP1AR STON2 HIP1 AP1S1 EPS15 COMT BMP2K GULP1 AP2A1 AMPH AP1G2 REPS1 SP1 SMAP2 RALBP1 | hippocampus |
| HPA:0270362 | 0.0164967356246 | 0.596774193548 | GAK AP1B1 SEC24B NECAP2 FCHO2 NUMB RALBP1 AP2A2 AP1S3 AAGAB CLINT1 PAAT AP2B1 CLTC TNRC6A ITSN1 AP1S2 MEA1 AFTPH AP1G1 WNK1 SYNRG HEATR5B AP1AR ZNF106 STON2 BMP2K AP1S1 EPS15 HIP1 GULP1 EPN1 ITSN2 AP1G2 REPS1 SP1 EPS15L1 | kidney; cells in tubules[>=Medium] |
| HPA:0550052 | 0.0169001577899 | 0.629032258065 | GAK SEC24B FCHO2 NUMB SEC16A EPS15L1 GKN1 AP2A2 SYNJ1 AP1S3 AAGAB CLINT1 PAAT AP2B1 CLTC TNRC6A ITSN1 AP1S2 AFTPH AP1G1 EPS15 SYNRG HEATR5B AP1AR ZNF106 STON2 HIP1 AP1S1 COMT BMP2K GULP1 EPN1 AP2A1 ITSN2 AP1G2 REPS1 SP1 SMAP2 RALBP1 | stomach 2; glandular cells[>=Medium] |
| TF:M03987 | 0.0184984887283 | 0.290322580645 | AAK1 PAAT BMP2K CCDC32 EPN1 TNRC6A NECAP2 GAK PIK3C2A AP1M1 SEC16A AP1AR HEATR5B SMAP2 AP1B1 AP2S1 AP2M1 MEA1 | Factor: FEV; motif: ACCGGAAGTN |
| HPA:0091063 | 0.0210279097491 | 0.0806451612903 | AAK1 SYNJ1 AMPH AP2A2 DNAJC6 | cerebellum; synaptic glomeruli - core[High] |
| TF:M02061 | 0.0237715623184 | 0.403225806452 | GAK NUMB PIK3C2A SEC16A PAAT AAK1 AP1S3 CLINT1 TNRC6A AP2S1 AP1M1 AP1S2 MEA1 CCDC32 AP1B1 AP1G1 NECAP2 HEATR5B AP2M1 COMT BMP2K EPN1 SYNJ1 AP1AR SMAP2 | Factor: ERF; motif: ACCGGAARYN |
| HPA:0270361 | 0.0252350533702 | 0.661290322581 | GAK AP1B1 SEC24B NECAP2 FCHO2 NUMB RALBP1 AP2A2 AAK1 AP1S3 AAGAB CLINT1 PAAT AP2B1 CLTC TNRC6A ITSN1 AP1S2 MEA1 CLTCL1 AFTPH AP1G1 WNK1 SYNRG HEATR5B AP1AR ZNF106 STON2 BMP2K AP1S1 EPS15 HIP1 GULP1 EPN1 AP2A1 ITSN2 AP1G2 SYNJ1 REPS1 SP1 EPS15L1 | kidney; cells in tubules[>=Low] |
| HPA:0270000 | 0.0297721174649 | 0.725806451613 | GAK AP1B1 SEC24B NECAP2 DNAJC6 FCHO2 NUMB SEC16A RALBP1 AP2A2 AAK1 AP1S3 AAGAB CLINT1 PAAT AP2B1 CLTC TNRC6A ITSN1 AP1S2 MEA1 CLTCL1 AFTPH WNK1 AP1G1 SYNRG AMPH HEATR5B AP1AR ZNF106 STON2 BMP2K AP1S1 EPS15 COMT HIP1 GULP1 EPN1 AP2A1 ITSN2 AP1G2 SYNJ1 REPS1 SP1 EPS15L1 | kidney |
| TF:M03972 | 0.0302266482353 | 0.274193548387 | AAK1 NECAP2 MEA1 CCDC32 EPN1 TNRC6A GAK PIK3C2A AP1M1 SEC16A AP1AR PAAT SMAP2 AP1B1 AP2S1 AP2M1 BMP2K | Factor: ELK3; motif: ACCGGAAGTN |
| REAC:R-HSA-9006934 | 0.0305828429745 | 0.145161290323 | EPN1 AP2A1 EPS15 AP2M1 AP2B1 EPS15L1 AP2S1 AP2A2 CLTC | Signaling by Receptor Tyrosine Kinases |
| HPA:0550000 | 0.0313403006852 | 0.693548387097 | GAK AP1B1 SEC24B NECAP2 FCHO2 NUMB SEC16A RALBP1 GKN1 AP2A2 SYNJ1 AP1S3 AAGAB CLINT1 PAAT AP2B1 CLTC TNRC6A ITSN1 AP1S2 MEA1 AFTPH WNK1 AP1G1 SYNRG HEATR5B AP1AR ZNF106 STON2 BMP2K AP1S1 EPS15 COMT HIP1 GULP1 EPN1 AP2A1 ITSN2 AP1G2 REPS1 SP1 SMAP2 EPS15L1 | stomach 2 |
| HPA:0550051 | 0.0313403006852 | 0.693548387097 | GAK AP1B1 SEC24B NECAP2 FCHO2 NUMB SEC16A RALBP1 GKN1 AP2A2 SYNJ1 AP1S3 AAGAB CLINT1 PAAT AP2B1 CLTC TNRC6A ITSN1 AP1S2 MEA1 AFTPH WNK1 AP1G1 SYNRG HEATR5B AP1AR ZNF106 STON2 BMP2K AP1S1 EPS15 COMT HIP1 GULP1 EPN1 AP2A1 ITSN2 AP1G2 REPS1 SP1 SMAP2 EPS15L1 | stomach 2; glandular cells[>=Low] |
| HPA:0250131 | 0.0316163228729 | 0.612903225806 | GAK AP1B1 SEC24B NECAP2 DNAJC6 NUMB SEC16A EPS15L1 AP2A2 AAK1 AP1S3 AAGAB CLINT1 PAAT AP2B1 CLTC TNRC6A RUNDC3A ITSN1 SYNJ1 AFTPH EPS15 AP1G1 SYNRG HEATR5B AP1AR STON2 HIP1 AP1S1 COMT BMP2K AP2A1 AMPH AP1G2 REPS1 SP1 SMAP2 RALBP1 | hippocampus; neuronal cells[>=Low] |
| GO:0000323 | 0.0320525146839 | 0.209677419355 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 AP1G1 AP2M1 AP2A2 AP2B1 CLTC AP2A1 AP2S1 AP1M1 | lytic vacuole |
| GO:0005764 | 0.0320525146839 | 0.209677419355 | AP1S1 AP1S3 AP1M2 AP1S2 AP1B1 AP1G1 AP2M1 AP2A2 AP2B1 CLTC AP2A1 AP2S1 AP1M1 | lysosome |
| WP:WP4829 | 0.0338231943576 | 0.0483870967742 | AP2B1 AP2A2 AP2A1 | mBDNF and proBDNF regulation of GABA neurotransmission |
| GO:0005737 | 0.0341489498205 | 0.887096774194 | GAK AP1B1 SEC24B NECAP2 DNAJC6 FCHO2 NUMB SEC16A RALBP1 ZNF106 GKN1 AP2A2 ITSN2 AAK1 AP1S3 STON2 AAGAB CLINT1 REPS2 AP2B1 CLTC TNRC6A AP2S1 AP1M1 ITSN1 AP1S2 NECAP1 CLTCL1 AFTPH EPS15L1 AP1G1 WNK1 SYNRG AMPH KIF13A DENND1A AP2M1 HIP1 AP1S1 EPS15 COMT BMP2K EPN1 STAMBP STAMBPL1 PAAT PIK3C2A AP1M2 AP1G2 SYNJ1 REPS1 AP2A1 AP1AR SMAP2 HEATR5B | cytoplasm |
| TF:M09613 | 0.0344738363059 | 0.564516129032 | CCDC32 GAK AP1B1 STAMBP NECAP2 FCHO2 ITSN2 SEC16A RALBP1 PAAT RSKR AAGAB NUMB CLTC TNRC6A AP2S1 AP1M1 AP1S2 MEA1 AAK1 AFTPH EPS15 AP1G1 SYNRG AP1AR ZNF106 AP2M1 COMT CLTCL1 BMP2K EPN1 PIK3C2A RUNDC3A SP1 SMAP2 | Factor: Fli-1; motif: RCMGGAAGYGNNN |
| HPA:0020051 | 0.0440469800091 | 0.677419354839 | GAK AP1B1 SEC24B NECAP2 FCHO2 NUMB SEC16A RALBP1 AP2A2 SYNJ1 AP1S3 AAGAB CLINT1 PAAT AP2B1 CLTC TNRC6A ITSN1 AP1S2 MEA1 CLTCL1 AFTPH WNK1 AP1G1 SYNRG HEATR5B AP1AR ZNF106 STON2 BMP2K AP1S1 EPS15 COMT HIP1 GULP1 AP2A1 EPN1 AP1G2 REPS1 SP1 SMAP2 EPS15L1 | adrenal gland; glandular cells[>=Low] |
| HPA:0020000 | 0.0447815621168 | 0.677419354839 | GAK AP1B1 SEC24B NECAP2 FCHO2 NUMB SEC16A RALBP1 AP2A2 SYNJ1 AP1S3 AAGAB CLINT1 PAAT AP2B1 CLTC TNRC6A ITSN1 AP1S2 MEA1 CLTCL1 AFTPH WNK1 AP1G1 SYNRG HEATR5B AP1AR ZNF106 STON2 BMP2K AP1S1 EPS15 COMT HIP1 GULP1 AP2A1 EPN1 AP1G2 REPS1 SP1 SMAP2 EPS15L1 | adrenal gland |
| TF:M11432 | 0.048481360773 | 0.629032258065 | GAK AP1B1 NECAP2 DNAJC6 NUMB SEC16A RALBP1 AP2A2 ITSN2 AAK1 AAGAB CLINT1 REPS2 TNRC6A AP2S1 AP1M1 AP1S2 MEA1 CCDC32 AFTPH EPS15 AP1G1 SYNRG AMPH HEATR5B AP1AR DENND1A AP2M1 COMT CLTCL1 BMP2K EPN1 AP2A1 PAAT PIK3C2A RUNDC3A SYNJ1 SP1 SMAP2 | Factor: Elk-1; motif: NACMGGAAGTN |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| AP2A2 | AP2M1 | 1.0 | 0.418 |
mixed_interface
|
| RALBP1 | REPS1 | 1.0 | 0.374 |
structurally_consistent (dimer)
|
| AP2S1 | AP2A1 | 1.0 | 0.71 |
structurally_consistent (dimer)
|
| AP2B1 | AP2A1 | 1.0 | 0.93 |
structurally_consistent (dimer)
|
| AP2M1 | EPS15 | 1.0 | 0.25 | |
| AP1B1 | AP1S2 | 1.0 | 0.24 |
mutually_exclusive (O43747)
|
| AP2B1 | AP1S2 | 1.0 | 0.142 | |
| AP1M1 | AP1B1 | 1.0 | 0.434 |
structurally_consistent (dimer)
|
| AP2A2 | AP2B1 | 1.0 | 0.336153846154 | |
| AP2S1 | AP2M1 | 1.0 | 0.706 |
mixed_interface
|
| AP2S1 | AAK1 | 1.0 | 0.132 | |
| AP1S2 | AP1G2 | 1.0 | 0.104 |
structurally_consistent (dimer)
|
| AP1B1 | AP1G1 | 1.0 | 0.682 |
mixed_interface
|
| RALBP1 | REPS2 | 1.0 | 0.28 |
structurally_consistent (dimer)
|
| AP2B1 | AP2S1 | 1.0 | 0.7 |
structurally_consistent (O95782)
|
| NECAP2 | AP2M1 | 1.0 | 0.1 |
structurally_consistent (dimer)
|
| AP2A2 | AP2S1 | 1.0 | 0.282 |
structurally_consistent (dimer)
|
| ITSN1 | AP2M1 | 1.0 | ||
| CCDC32 | AP2S1 | 1.0 | 0.13 |
structurally_consistent (dimer)
|
| AP1M2 | AP1G1 | 1.0 | 0.068 |
mixed_interface
|
| AP2M1 | AAK1 | 1.0 | 0.224 | |
| AP1M1 | AP1S2 | 1.0 | 0.28 |
mutually_exclusive (O43747)
structurally_consistent (dimer) |
| AP1S2 | AP1G1 | 1.0 | 0.226 |
structurally_consistent (dimer)
|
| AP1M1 | AP1G1 | 1.0 | 0.538 |
structurally_consistent (Q10567)
structurally_consistent (dimer) |
| AP2S1 | EPS15 | 1.0 | 0.104 |
structurally_consistent (dimer)
|
| AP2B1 | EPS15 | 1.0 | 0.186 | |
| AP2B1 | AP2M1 | 1.0 | 0.826 |
structurally_consistent (dimer)
|
| AP2B1 | NECAP2 | 1.0 | 0.09 |
mutually_exclusive (Q96CW1)
|
| AP1S2 | HEATR5B | 1.0 | 0.114 | |
| AP2S1 | AP1B1 | 1.0 | 0.258 | |
| NECAP2 | AP2A1 | 1.0 | 0.184 | |
| EPS15L1 | AP2M1 | 1.0 | 0.186 | |
| AP2M1 | AP1B1 | 1.0 | 0.384 |
structurally_consistent (dimer)
|
| AP1B1 | AP1M2 | 1.0 | 0.218 |
structurally_consistent (Q9BXS5)
structurally_consistent (dimer) |
| NECAP2 | AP1B1 | 0.999 | 0.14 |
mutually_exclusive (Q96CW1)
|
| EPS15L1 | EPS15 | 0.999 | 0.182 |
mutually_exclusive (Q59EK9)
|
| AP2B1 | AP1B1 | 0.999 | 0.718 |
mutually_exclusive (Q9Y6Q5)
|
| REPS1 | AAK1 | 0.999 | 0.036 | |
| RUNDC3A | RUNDC3B | 0.999 | ||
| EPS15L1 | AP2S1 | 0.999 | 0.222 | |
| EPS15L1 | AP2A1 | 0.999 | 0.32 | |
| PIK3C2A | STAMBPL1 | 0.999 | 0.0870769230769 | |
| AP1G2 | AP1M2 | 0.999 | 0.072 |
structurally_consistent (dimer)
|
| AP2A2 | NECAP2 | 0.999 | 0.138416666667 | |
| AP1B1 | AP2A1 | 0.999 | 0.49 | |
| ITSN1 | AP2S1 | 0.999 | ||
| CCDC32 | AAGAB | 0.999 | 0.11 |
mutually_exclusive (P53680)
|
| AP2B1 | ITSN1 | 0.999 | ||
| STAMBPL1 | CLINT1 | 0.999 | 0.134 | |
| AP1S2 | AP1AR | 0.999 | 0.052 | |
| AP1S2 | AFTPH | 0.999 | 0.072 | |
| STAMBP | CLINT1 | 0.999 | 0.162 |
structurally_consistent (dimer)
|
| AP2B1 | AP1M2 | 0.999 | 0.026 |
structurally_consistent (dimer)
|
| NECAP2 | AP2S1 | 0.999 | 0.076 |
structurally_consistent (dimer)
|
| AP2M1 | AP2A1 | 0.999 | 0.956 |
mutually_exclusive (P53680)
|
| AP2A2 | AAGAB | 0.999 | 0.1305 | |
| EPS15L1 | FCHO2 | 0.999 | 0.138 | |
| AP2B1 | STON2 | 0.999 | 0.134 | |
| AP1S1 | AP1M2 | 0.999 | 0.072 |
mutually_exclusive (O43747)
structurally_consistent (dimer) |
| AP1B1 | AP1S3 | 0.999 | 0.174 | |
| AP2A2 | EPS15L1 | 0.999 | 0.313555555556 | |
| AP2B1 | EPS15L1 | 0.999 | 0.446 | |
| AP1S2 | SYNRG | 0.999 | 0.152 | |
| EPS15 | AP2A1 | 0.999 | 0.186 | |
| AP2S1 | FCHO2 | 0.999 | 0.074 |
structurally_consistent (dimer)
|
| AP2B1 | FCHO2 | 0.999 | 0.114 | |
| AP1B1 | MEA1 | 0.999 | 0.084 | |
| SYNRG | AFTPH | 0.999 | 0.126 | |
| HEATR5B | AP1S3 | 0.999 | 0.032 | |
| BMP2K | AP2A1 | 0.999 | 0.184 | |
| AP2S1 | BMP2K | 0.999 | 0.186 | |
| AP1S3 | AP1G1 | 0.999 | 0.188 |
structurally_consistent (dimer)
|
| AP1M2 | AP1S3 | 0.999 | 0.024 | |
| AP1S2 | AP1M2 | 0.999 | 0.174 |
mutually_exclusive (O75843)
|
| AP2S1 | REPS1 | 0.999 | 0.044 | |
| FCHO2 | EPS15 | 0.998 | 0.142545454545 | |
| AAGAB | AP1S2 | 0.998 | 0.072 |
mutually_exclusive (O75843)
|
| AAGAB | AP2S1 | 0.998 | 0.058 |
structurally_consistent (dimer)
|
| PIK3C2A | CLINT1 | 0.998 | 0.068 | |
| AP2A2 | AP1B1 | 0.998 | 0.266 |
mutually_exclusive (O43747)
|
| AP1M1 | AP1S3 | 0.998 | 0.082 |
mutually_exclusive (O43747)
|
| AP2B1 | AP1M1 | 0.998 | 0.39 |
structurally_consistent (dimer)
|
| EPS15L1 | ITSN1 | 0.998 | ||
| AP2M1 | AP1G1 | 0.998 | 0.302 |
mutually_exclusive (P53680)
|
| REPS1 | EPS15 | 0.998 | 0.07 | |
| AP2A1 | AAK1 | 0.998 | 0.158 | |
| FCHO2 | AP2A1 | 0.998 | 0.188275862069 | |
| AFTPH | AP1S3 | 0.998 | 0.064 | |
| AP1M2 | MEA1 | 0.998 | 0.068 |
mutually_exclusive (Q9BXS5)
structurally_consistent (dimer) |
| BMP2K | AAK1 | 0.998 | 0.47 | |
| STAMBPL1 | GAK | 0.998 | 0.056 | |
| BMP2K | CLTC | 0.998 | 0.233142857143 | |
| AP2S1 | STON2 | 0.998 | 0.09 | |
| REPS2 | REPS1 | 0.998 | 0.144 |
mutually_exclusive (Q15311)
|
| AP2A2 | CCDC32 | 0.998 | 0.13 | |
| RALBP1 | AP2A1 | 0.998 | 0.14 | |
| AP2B1 | AP1G1 | 0.998 | 0.532 |
mutually_exclusive (Q9Y6Q5)
|
| AP2B1 | AAK1 | 0.998 | 0.198 | |
| AP2B1 | MEA1 | 0.998 | 0.086 | |
| AAGAB | AP2A1 | 0.998 | 0.1085 | |
| REPS1 | STON2 | 0.998 | 0.092 | |
| KIF13A | AP1S3 | 0.997 | ||
| AP1M1 | MEA1 | 0.997 | 0.084 |
mutually_exclusive (Q9Y6Q5)
structurally_consistent (dimer) |
| AP2B1 | BMP2K | 0.997 | 0.142 | |
| AP2M1 | BMP2K | 0.997 | 0.168 | |
| AP2B1 | AP1S3 | 0.997 | 0.16 | |
| AP2M1 | MEA1 | 0.997 | 0.124 |
structurally_consistent (dimer)
|
| AP2M1 | RALBP1 | 0.997 | 0.116 |
structurally_consistent (dimer)
|
| AP2B1 | REPS1 | 0.997 | 0.152 | |
| SYNRG | AP1S3 | 0.997 | 0.078 | |
| AP2M1 | REPS1 | 0.997 | 0.13 | |
| FCHO2 | STON2 | 0.997 | 0.066 | |
| AP1B1 | EPS15 | 0.997 | 0.198 | |
| AP2A1 | STON2 | 0.997 | 0.162 | |
| BMP2K | REPS1 | 0.997 | 0.068 | |
| ITSN2 | EPS15L1 | 0.997 | 0.118 | |
| REPS1 | STAMBP | 0.997 | 0.05 | |
| EPS15L1 | AP1B1 | 0.997 | 0.38 | |
| PIK3C2A | BMP2K | 0.997 | 0.156 | |
| CLINT1 | GAK | 0.996 | 0.098 |
mutually_exclusive (O95630)
|
| BMP2K | EPS15 | 0.996 | 0.044 | |
| ITSN1 | AP1B1 | 0.996 | ||
| STAMBPL1 | CLTC | 0.996 | 0.166 | |
| EPS15 | AAK1 | 0.996 | 0.052 | |
| AAGAB | AP1S3 | 0.996 | 0.046 |
mutually_exclusive (O75843)
|
| STAMBPL1 | SEC16A | 0.996 | ||
| AP1B1 | AP1G2 | 0.996 | 0.052 |
mutually_exclusive (Q9Y6Q5)
|
| ITSN2 | AP2M1 | 0.996 | 0.166 | |
| REPS1 | AP2A1 | 0.996 | 0.112 | |
| RUNDC3A | AAK1 | 0.996 | 0.09 | |
| CLINT1 | AAK1 | 0.996 | 0.11 | |
| RUNDC3A | EPS15 | 0.996 | 0.074 |
structurally_consistent (dimer)
|
| AP2M1 | DENND1A | 0.996 | 0.312 | |
| AP2A2 | EPS15 | 0.996 | 0.218 | |
| NECAP2 | NECAP1 | 0.996 | 0.076 | |
| BMP2K | STON2 | 0.995 | 0.058 | |
| EPS15 | STON2 | 0.995 | 0.11 | |
| AP2B1 | CLINT1 | 0.995 | 0.268 | |
| AP2M1 | AP1S3 | 0.995 | 0.098 | |
| AP2M1 | GULP1 | 0.995 | 0.122 | |
| HEATR5B | AFTPH | 0.995 | 0.326 | |
| EPS15L1 | RUNDC3A | 0.995 | 0.09 |
structurally_consistent (dimer)
|
| RALBP1 | AAK1 | 0.995 | 0.154 | |
| STAMBPL1 | EPS15 | 0.995 | 0.066 | |
| CLTCL1 | STAMBPL1 | 0.994 | 0.141 |
structurally_consistent (dimer)
|
| FCHO2 | AP1B1 | 0.994 | 0.208 | |
| ZNF106 | STON2 | 0.994 | 0.1 | |
| ZNF106 | STAMBPL1 | 0.994 | 0.106 | |
| PIK3C2A | CLTC | 0.994 | 0.398 | |
| AP2A2 | AP2A1 | 0.994 | 0.3585 | |
| CCDC32 | AP2A1 | 0.994 | 0.132 | |
| PIK3C2A | CLTCL1 | 0.994 | 0.136 | |
| AP1AR | AP1S3 | 0.994 | 0.096 | |
| HEATR5B | AP1G1 | 0.994 | 0.048 | |
| AP2M1 | STON2 | 0.994 | 0.138 | |
| AP2S1 | RALBP1 | 0.993 | 0.204 | |
| AP1B1 | HEATR5B | 0.993 | 0.224 | |
| NUMB | GAK | 0.993 | 0.082 | |
| AP2A2 | RUNDC3A | 0.993 | 0.142 | |
| CLTCL1 | STAMBP | 0.993 | 0.126 | |
| EPN1 | NUMB | 0.993 | 0.048 | |
| AP1G2 | AP1G1 | 0.993 | 0.096 |
mutually_exclusive (Q9Y6Q5)
structurally_consistent (dimer) |
| AP1S2 | CLINT1 | 0.993 | 0.076 | |
| FCHO2 | BMP2K | 0.993 | 0.11 | |
| CLINT1 | AP2A1 | 0.992 | 0.224 | |
| AP2M1 | RUNDC3A | 0.992 | 0.086 | |
| RALBP1 | BMP2K | 0.992 | 0.104 | |
| AP2B1 | AP1G2 | 0.992 | 0.084 |
mutually_exclusive (Q9Y6Q5)
|
| BMP2K | STAMBPL1 | 0.992 | 0.126 | |
| AP2M1 | AP1S1 | 0.992 | 0.078 | |
| AP1S2 | MEA1 | 0.992 | 0.038 | |
| AP1G2 | AP1S3 | 0.991 | 0.046 |
structurally_consistent (dimer)
|
| BMP2K | CLINT1 | 0.991 | 0.072 | |
| SYNJ1 | PAAT | 0.991 | 0.142 | |
| STAMBP | CLTC | 0.991 | 0.334 | |
| RALBP1 | RUNDC3A | 0.991 | 0.078 | |
| SYNRG | HEATR5B | 0.991 | 0.125 | |
| DENND1A | HIP1 | 0.991 | 0.104 | |
| STON2 | GAK | 0.991 | 0.11 | |
| PAAT | STAMBP | 0.99 | 0.094 | |
| HEATR5B | AP1G2 | 0.99 | 0.064 | |
| RUNDC3A | AP2A1 | 0.99 | 0.13 | |
| CLTCL1 | NUMB | 0.99 | 0.158 | |
| WNK1 | NUMB | 0.99 | 0.068 | |
| AP2M1 | NECAP1 | 0.99 | 0.158 |
structurally_consistent (dimer)
|
| REPS1 | CLINT1 | 0.99 | 0.156 | |
| EPN1 | STAMBP | 0.99 | 0.066 | |
| AAGAB | AP2M1 | 0.99 | 0.086 |
mutually_exclusive (P53680)
|
| AP1S2 | AP1S3 | 0.99 | 0.062 | |
| CLTCL1 | CLINT1 | 0.989 | 0.088 | |
| AP2M1 | AP1S2 | 0.989 | 0.192 | |
| AP2B1 | NECAP1 | 0.989 | 0.108 | |
| STON2 | NUMB | 0.989 | 0.14 | |
| WNK1 | STAMBPL1 | 0.989 | 0.04 | |
| AFTPH | AP1G1 | 0.989 | 0.09 | |
| AP2B1 | AP1S1 | 0.989 | 0.186 | |
| CCDC32 | AP2M1 | 0.989 | 0.104 |
mutually_exclusive (P53680)
|
| REPS1 | STAMBPL1 | 0.989 | 0.064 | |
| STAMBPL1 | NUMB | 0.988 | 0.101333333333 | |
| AP1S1 | AAK1 | 0.988 | 0.036 | |
| NECAP1 | REPS1 | 0.988 | 0.09 | |
| SMAP2 | NUMB | 0.988 | 0.032085106383 | |
| BMP2K | WNK1 | 0.988 | 0.17 | |
| AAGAB | AP1G1 | 0.988 | 0.082 | |
| AP1S1 | SYNJ1 | 0.987 | 0.072 | |
| ZNF106 | CLTCL1 | 0.987 | 0.092 | |
| SMAP2 | CLINT1 | 0.987 | 0.046 | |
| GAK | CLTC | 0.987 | 0.294 | |
| FCHO2 | AP2M1 | 0.987 | 0.104 |
structurally_consistent (dimer)
|
| AP1M1 | AP1G2 | 0.987 | 0.016 |
mutually_exclusive (P56377)
|
| PAAT | CLTC | 0.986 | 0.178325 | |
| PAAT | REPS1 | 0.986 | 0.08 | |
| RALBP1 | EPS15 | 0.986 | 0.09 | |
| KIF13A | AP1M2 | 0.986 | ||
| DENND1A | NUMB | 0.986 | 0.156 | |
| EPN1 | AAK1 | 0.986 | 0.1 | |
| AP1M1 | AFTPH | 0.986 | 0.154 | |
| BMP2K | HIP1 | 0.986 | 0.066 | |
| AP1S1 | AP1B1 | 0.985 | 0.112 |
mutually_exclusive (O43747)
|
| FCHO2 | NECAP1 | 0.985 | 0.102 | |
| AP1M1 | SYNRG | 0.985 | 0.182 | |
| EPS15L1 | RALBP1 | 0.985 | 0.126 | |
| BMP2K | SEC16A | 0.985 | ||
| AP2B1 | RALBP1 | 0.985 | 0.124 |
mutually_exclusive (Q96CW1)
|
| ITSN2 | ITSN1 | 0.985 | ||
| SYNRG | AP1G1 | 0.985 | 0.23 | |
| NECAP1 | NUMB | 0.984 | 0.116 | |
| BMP2K | STAMBP | 0.984 | 0.058 | |
| AP1B1 | NECAP1 | 0.984 | 0.278 |
structurally_consistent (dimer)
|
| AP1B1 | AFTPH | 0.984 | 0.184 | |
| MEA1 | AP1G1 | 0.984 | 0.076 | |
| STAMBPL1 | STAMBP | 0.984 | 0.03 | |
| PIK3C2A | ZNF106 | 0.983 | 0.128 | |
| SMAP2 | STAMBPL1 | 0.983 | 0.04 | |
| WNK1 | STON2 | 0.983 | 0.072 | |
| AP2M1 | NUMB | 0.983 | 0.096 | |
| AP1B1 | RALBP1 | 0.983 | 0.16 |
mutually_exclusive (Q96CW1)
|
| DENND1A | STAMBPL1 | 0.982 | 0.118 | |
| ITSN2 | AP2S1 | 0.982 | 0.084 | |
| BMP2K | ZNF106 | 0.982 | 0.052 | |
| AP2A2 | STON2 | 0.982 | 0.166 | |
| ZNF106 | SEC16A | 0.982 | ||
| NECAP1 | BMP2K | 0.982 | 0.134 | |
| FCHO2 | AP1S1 | 0.982 | 0.068 | |
| PIK3C2A | DENND1A | 0.981 | 0.12 | |
| AP2B1 | RUNDC3A | 0.981 | 0.152 | |
| ZNF106 | GAK | 0.981 | 0.096 | |
| HIP1 | AP2A1 | 0.981 | 0.152 | |
| FCHO2 | NUMB | 0.981 | 0.206 | |
| ZNF106 | WNK1 | 0.981 | 0.05 | |
| AP2B1 | AAGAB | 0.981 | 0.13 | |
| RALBP1 | STON2 | 0.98 | 0.138 | |
| WNK1 | GAK | 0.98 | 0.114 | |
| STAMBPL1 | STON2 | 0.98 | 0.106 | |
| PIK3C2A | SEC16A | 0.98 | ||
| FCHO2 | AAK1 | 0.98 | 0.028 | |
| AP1S1 | AP1M1 | 0.98 | 0.248 | |
| AAK1 | GAK | 0.979 | 0.166 | |
| AP1G2 | AFTPH | 0.979 | 0.06 | |
| PIK3C2A | GAK | 0.979 | 0.14 | |
| DENND1A | AAK1 | 0.979 | 0.086 | |
| AP2M1 | CLINT1 | 0.979 | 0.148 | |
| AP2A2 | RALBP1 | 0.978 | 0.168 | |
| CLTCL1 | CLTC | 0.978 | 0.534 | |
| HIP1 | AAK1 | 0.978 | 0.026 | |
| AP1S1 | AP1S3 | 0.978 | 0.2 | |
| MEA1 | AP1S3 | 0.978 | 0.07 | |
| DENND1A | CLTCL1 | 0.977 | 0.126 | |
| NECAP1 | CLINT1 | 0.977 | 0.136 | |
| AP2A2 | ITSN1 | 0.976 | ||
| DENND1A | BMP2K | 0.976 | 0.12 | |
| WNK1 | STAMBP | 0.976 | 0.084 | |
| STAMBPL1 | AAK1 | 0.976 | 0.056 | |
| AP2M1 | PIK3C2A | 0.976 | 0.175 | |
| AP2M1 | SYNJ1 | 0.976 | 0.155166666667 | |
| PAAT | STAMBPL1 | 0.976 | 0.084 |
structurally_consistent (dimer)
|
| CLINT1 | CLTC | 0.976 | 0.295 | |
| NECAP1 | AAK1 | 0.976 | 0.09 | |
| EPN1 | BMP2K | 0.975 | 0.266 | |
| ITSN2 | AP2A1 | 0.975 | 0.18 | |
| ITSN1 | RALBP1 | 0.975 | ||
| AP1S1 | MEA1 | 0.975 | 0.03 | |
| REPS2 | AAK1 | 0.975 | 0.0945 | |
| NECAP1 | AP1G1 | 0.974 | 0.126 |
mutually_exclusive (P53680)
|
| REPS1 | AP1G1 | 0.974 | 0.086 | |
| AP2S1 | AP1S3 | 0.974 | 0.098 |
mutually_exclusive (O43747)
|
| AP1B1 | STON2 | 0.974 | 0.174 | |
| STAMBPL1 | AP2A1 | 0.974 | 0.132 | |
| AP2B1 | CCDC32 | 0.974 | 0.06 | |
| TNRC6A | STAMBPL1 | 0.973 | 0.12 | |
| AAK1 | NUMB | 0.973 | 0.056 | |
| ITSN2 | AP1B1 | 0.973 | 0.126 | |
| DENND1A | STON2 | 0.973 | 0.106 | |
| SYNJ1 | NECAP1 | 0.972 | 0.202 | |
| EPN1 | REPS1 | 0.972 | 0.062 | |
| WNK1 | REPS1 | 0.972 | 0.104 | |
| AP1B1 | SYNRG | 0.972 | 0.179 | |
| AP1S1 | AP1G1 | 0.971 | 0.402666666667 |
structurally_consistent (dimer)
|
| AP2A2 | AP1S3 | 0.971 | 0.142 |
structurally_consistent (O43747)
|
| EPN1 | STON2 | 0.971 | 0.096 | |
| EPS15 | NUMB | 0.971 | 0.06 | |
| PIK3C2A | STAMBP | 0.97 | 0.064 | |
| RALBP1 | STAMBP | 0.97 | 0.12 | |
| BMP2K | NUMB | 0.97 | 0.136 | |
| NECAP1 | STON2 | 0.97 | 0.108 | |
| CLINT1 | EPS15 | 0.97 | 0.252 | |
| DNAJC6 | GULP1 | 0.97 | 0.082 | |
| EPS15L1 | STON2 | 0.97 | 0.122 | |
| DENND1A | GAK | 0.97 | 0.14 | |
| AP2S1 | RUNDC3A | 0.97 | 0.054 | |
| EPS15 | GAK | 0.969 | 0.082 | |
| EPN1 | NECAP1 | 0.969 | 0.16 | |
| AP1S1 | NECAP1 | 0.968 | 0.048 |
structurally_consistent (Q9Y6Q5)
|
| DENND1A | EPS15 | 0.968 | 0.108 | |
| HIP1 | STAMBPL1 | 0.968 | 0.062 | |
| AP2B1 | DENND1A | 0.967 | 0.280666666667 | |
| GULP1 | REPS1 | 0.967 | 0.084 | |
| ZNF106 | NUMB | 0.967 | 0.052 | |
| AP1S1 | AP1S2 | 0.966 | 0.056 |
mutually_exclusive (O43747)
|
| FCHO2 | SYNJ1 | 0.966 | 0.138 | |
| AP1M1 | NECAP1 | 0.966 | 0.22 |
structurally_consistent (dimer)
|
| SMAP2 | GAK | 0.966 | 0.118 | |
| PIK3C2A | NUMB | 0.966 | 0.09 | |
| DENND1A | AP2A1 | 0.965 | 0.12 | |
| EPN1 | STAMBPL1 | 0.965 | 0.082 | |
| NECAP1 | EPS15 | 0.965 | 0.146 | |
| CLTCL1 | GAK | 0.965 | 0.184 | |
| AP1B1 | REPS1 | 0.965 | 0.114 | |
| CLINT1 | STON2 | 0.964 | 0.1 | |
| EPN1 | WNK1 | 0.964 | 0.066 | |
| FCHO2 | REPS1 | 0.964 | 0.04 | |
| AP1S3 | AP2A1 | 0.964 | 0.132 | |
| AP2A2 | ITSN2 | 0.963 | 0.36 | |
| AP1S2 | AP2A1 | 0.963 | 0.104 | |
| WNK1 | HIP1 | 0.963 | 0.022 | |
| SYNJ1 | RALBP1 | 0.963 | 0.136 | |
| HIP1 | STAMBP | 0.962 | 0.048 | |
| RALBP1 | CLINT1 | 0.962 | 0.11 | |
| PIK3C2A | AP2A1 | 0.962 | 0.166 | |
| AP1B1 | SYNJ1 | 0.961 | 0.194 | |
| AP1S3 | STON2 | 0.961 | 0.09 | |
| CLTCL1 | SEC16A | 0.961 | ||
| AP2S1 | AP1S2 | 0.961 | 0.176 | |
| AP2B1 | STAMBPL1 | 0.961 | 0.08 | |
| ZNF106 | AP2A1 | 0.959 | 0.116 | |
| AP2A2 | FCHO2 | 0.959 | 0.146 | |
| ITSN1 | EPS15 | 0.959 | ||
| PAAT | HIP1 | 0.959 | 0.06 | |
| PIK3C2A | AAK1 | 0.959 | 0.074 | |
| SYNJ1 | AP1G1 | 0.958 | 0.094 | |
| AP1S1 | RALBP1 | 0.958 | 0.062 | |
| AP1S1 | REPS1 | 0.958 | 0.052 | |
| PAAT | AAK1 | 0.958 | 0.084 | |
| WNK1 | EPS15 | 0.958 | 0.1 | |
| AP2B1 | STAMBP | 0.958 | 0.242 | |
| ITSN1 | STON2 | 0.957 | ||
| ITSN2 | AP2B1 | 0.957 | 0.082 | |
| BMP2K | GAK | 0.957 | 0.106 | |
| DENND1A | SEC16A | 0.956 | ||
| EPN1 | PAAT | 0.956 | 0.106 | |
| AP2B1 | NUMB | 0.956 | 0.152 | |
| ITSN1 | AP2A1 | 0.955 | ||
| HIP1 | GAK | 0.955 | 0.058 | |
| AP2A2 | AP1S2 | 0.955 | 0.166 | |
| STON2 | AAK1 | 0.955 | 0.074 | |
| TNRC6A | BMP2K | 0.954 | 0.102 | |
| AP1B1 | CLINT1 | 0.954 | 0.276 | |
| WNK1 | AAK1 | 0.954 | 0.06 | |
| RALBP1 | AP1G1 | 0.953 | 0.118 | |
| AP2A2 | AAK1 | 0.953 | 0.258 | |
| EPS15L1 | AAK1 | 0.953 | 0.122 | |
| DNAJC6 | CLINT1 | 0.953 | 0.124 | |
| AP1B1 | BMP2K | 0.953 | 0.222 | |
| CLTCL1 | HIP1 | 0.953 | 0.18 | |
| HEATR5B | AP1M2 | 0.953 | 0.086 | |
| SYNJ1 | REPS1 | 0.953 | 0.188 | |
| CLTCL1 | AP2A1 | 0.952 | 0.252352941176 | |
| SEC24B | BMP2K | 0.952 | 0.086 | |
| STAMBP | AP2A1 | 0.952 | 0.102 | |
| BMP2K | CLTCL1 | 0.952 | 0.088 | |
| STAMBP | SEC16A | 0.951 | ||
| AP2B1 | GAK | 0.951 | 0.224 | |
| AFTPH | AP1M2 | 0.951 | 0.044 | |
| SYNRG | AP1M2 | 0.951 | ||
| AP1S3 | CLINT1 | 0.95 | 0.134 | |
| KIF13A | AP1G1 | 0.95 | ||
| AP2A1 | NUMB | 0.95 | 0.118 | |
| RUNDC3A | CLINT1 | 0.949 | 0.114 | |
| ITSN1 | MEA1 | 0.949 | ||
| AP1S1 | AP1G2 | 0.949 | 0.028 |
structurally_consistent (dimer)
|
| AAGAB | AP1S1 | 0.948 | 0.038 |
mutually_exclusive (O75843)
structurally_consistent (dimer) |
| ZNF106 | EPS15 | 0.947 | 0.114 | |
| SYNRG | AP1G2 | 0.947 | 0.222 | |
| FCHO2 | RALBP1 | 0.947 | 0.078 | |
| AP1G2 | MEA1 | 0.946 | 0.014 | |
| MEA1 | EPS15 | 0.946 | 0.046 | |
| ITSN1 | AP1S3 | 0.946 | ||
| PAAT | CLTCL1 | 0.946 | 0.098 | |
| AP2A2 | AMPH | 0.945 | 0.226607843137 | |
| HIP1 | NUMB | 0.945 | 0.058 | |
| AP1S1 | STON2 | 0.945 | 0.074 | |
| PIK3C2A | HIP1 | 0.944 | 0.084 | |
| EPN1 | DENND1A | 0.944 | 0.144 | |
| AP1M1 | HEATR5B | 0.943 | 0.14 | |
| DENND1A | REPS1 | 0.943 | 0.174 | |
| DENND1A | CLINT1 | 0.943 | 0.094 | |
| AP1B1 | AP1AR | 0.942 | 0.094 | |
| AP2S1 | SYNJ1 | 0.942 | 0.086 | |
| GKN1 | CLTCL1 | 0.941 | ||
| FCHO2 | DENND1A | 0.94 | 0.054 | |
| TNRC6A | PIK3C2A | 0.94 | 0.198 | |
| EPN1 | SMAP2 | 0.94 | 0.104 | |
| AP2B1 | AMPH | 0.94 | 0.144 | |
| EPS15 | CLTC | 0.94 | 0.378 | |
| PIK3C2A | REPS1 | 0.94 | 0.05 | |
| EPN1 | RALBP1 | 0.938 | 0.05 | |
| STAMBP | GAK | 0.938 | 0.104 |
structurally_consistent (dimer)
|
| SMAP2 | STAMBP | 0.937 | 0.032 | |
| EPN1 | GAK | 0.937 | 0.068 | |
| PIK3C2A | EPS15 | 0.937 | 0.026 | |
| SP1 | WNK1 | 0.936 | 0.072 | |
| STON2 | CLTC | 0.936 | 0.256325 | |
| RUNDC3A | REPS1 | 0.935 | 0.076 |
structurally_consistent (dimer)
|
| ITSN2 | EPS15 | 0.935 | 0.15 | |
| PAAT | AP2A1 | 0.934 | 0.186 | |
| AP1AR | SYNRG | 0.933 | 0.088 | |
| EPS15L1 | MEA1 | 0.933 | 0.138 | |
| BMP2K | RUNDC3A | 0.933 | 0.106 | |
| EPN1 | EPS15 | 0.933 | 0.022 | |
| MEA1 | STON2 | 0.933 | 0.064 | |
| ITSN2 | FCHO2 | 0.932 | 0.052 | |
| AP1S1 | COMT | 0.932 | 0.08 | |
| FCHO2 | AP1S3 | 0.932 | 0.072 | |
| TNRC6A | CLTC | 0.932 | 0.242095238095 | |
| AP2A2 | BMP2K | 0.931 | 0.146 | |
| SMAP2 | ZNF106 | 0.931 | 0.034 | |
| HIP1 | SEC16A | 0.93 | ||
| AMPH | AP2A1 | 0.93 | 0.164 | |
| NECAP2 | AAK1 | 0.929 | 0.052 | |
| AP1S1 | AP2A1 | 0.929 | 0.204 |
structurally_consistent (dimer)
|
| AP2A2 | AP1S1 | 0.929 | 0.158235294118 |
structurally_consistent (O43747)
structurally_consistent (dimer) |
| PAAT | PIK3C2A | 0.928 | 0.126 | |
| AP1S1 | NUMB | 0.928 | 0.03 | |
| AP2A2 | REPS1 | 0.928 | 0.288079365079 | |
| NECAP2 | EPS15L1 | 0.927 | 0.096 | |
| EPS15L1 | REPS1 | 0.927 | 0.112 |
mutually_exclusive (Q59EK9)
|
| AP2M1 | AMPH | 0.927 | 0.341 | |
| PAAT | GULP1 | 0.926 | 0.1 | |
| ITSN1 | BMP2K | 0.924 | ||
| AP2B1 | SYNJ1 | 0.924 | 0.198 | |
| NECAP1 | RALBP1 | 0.924 | 0.142 |
mutually_exclusive (Q96CW1)
|
| AP2S1 | CLINT1 | 0.923 | 0.282 | |
| ITSN1 | REPS1 | 0.922 | ||
| SYNJ1 | AAK1 | 0.922 | 0.14 | |
| FCHO2 | SEC16A | 0.92 | ||
| SEC24B | DENND1A | 0.919 | 0.106 | |
| EPN1 | HIP1 | 0.918 | 0.042 | |
| AP1AR | AFTPH | 0.918 | 0.086 | |
| AP1M1 | SYNJ1 | 0.917 | 0.162 | |
| AP1AR | AP1G1 | 0.916 | 0.112 |
structurally_consistent (Q9BXS5)
structurally_consistent (dimer) |
| TNRC6A | CLINT1 | 0.916 | 0.138 | |
| GAK | SEC16A | 0.915 | ||
| AP1B1 | HIP1 | 0.914 | 0.064 | |
| AP2A1 | GAK | 0.913 | 0.11 | |
| SEC24B | AP1G1 | 0.913 | 0.186 | |
| NECAP2 | ITSN1 | 0.913 | ||
| AP1M1 | AP1M2 | 0.912 | 0.056 |
structurally_consistent (dimer)
|
| PIK3C2A | DNAJC6 | 0.911 | 0.236 | |
| HIP1 | STON2 | 0.91 | 0.1 | |
| SEC24B | PIK3C2A | 0.91 | 0.122 | |
| AP2S1 | MEA1 | 0.91 | 0.044 | |
| SMAP2 | WNK1 | 0.909 | 0.028 | |
| PAAT | CLINT1 | 0.907 | 0.078 | |
| AAGAB | AP1B1 | 0.907 | 0.066 | |
| STAMBP | NUMB | 0.907 | 0.02 | |
| AP2B1 | CLTC | 0.907 | 0.73 | |
| PIK3C2A | WNK1 | 0.906 | 0.07 | |
| ITSN1 | AAK1 | 0.905 | ||
| FCHO2 | AP1G1 | 0.905 | 0.086 |
mutually_exclusive (P53680)
|
| AAK1 | CLTC | 0.905 | 0.232 | |
| AP1AR | HEATR5B | 0.905 | 0.05 | |
| AP2M1 | CLTC | 0.903 | 0.611 | |
| SEC24B | CLINT1 | 0.903 | 0.106 | |
| EPN1 | PIK3C2A | 0.903 | 0.068 | |
| AP2B1 | TNRC6A | 0.902 | 0.33 | |
| AP2B1 | PIK3C2A | 0.902 | 0.13 | |
| DENND1A | CLTC | 0.901 | 0.218 | |
| STAMBP | STON2 | 0.901 | 0.068 | |
| HIP1 | REPS1 | 0.901 | 0.046 | |
| AP1B1 | KIF13A | 0.899 | ||
| AP1M1 | RALBP1 | 0.898 | 0.132 | |
| NECAP1 | AP2A1 | 0.898 | 0.168 |
mutually_exclusive (P53680)
|
| FCHO2 | SEC24B | 0.897 | 0.114 | |
| EPN1 | FCHO2 | 0.897 | 0.04 | |
| AP1S1 | CLINT1 | 0.896 | 0.23 | |
| REPS1 | CLTC | 0.896 | 0.22 | |
| AP1S2 | STON2 | 0.896 | 0.15 | |
| NECAP2 | AP1G1 | 0.894 | 0.108666666667 | |
| DNAJC6 | CLTC | 0.894 | 0.442666666667 | |
| AP1M1 | AP1AR | 0.893 | 0.062 |
structurally_consistent (dimer)
|
| AP1B1 | NUMB | 0.893 | 0.066 | |
| AP1AR | AP1G2 | 0.893 | 0.06 |
structurally_consistent (O43747)
|
| TNRC6A | STON2 | 0.892 | 0.118 | |
| AP2M1 | KIF13A | 0.892 | ||
| SEC24B | SEC16A | 0.891 | ||
| AP1B1 | AAK1 | 0.89 | 0.176 | |
| NECAP1 | SYNRG | 0.889 | 0.104 | |
| NECAP1 | DENND1A | 0.888 | 0.106 | |
| EPN1 | SYNJ1 | 0.887 | 0.125666666667 | |
| AP2M1 | GKN1 | 0.887 | ||
| PIK3C2A | STON2 | 0.884 | 0.144 | |
| NECAP1 | WNK1 | 0.884 | 0.088 | |
| RALBP1 | PIK3C2A | 0.884 | 0.11 | |
| RALBP1 | SMAP2 | 0.881 | 0.068 | |
| AP1S1 | SEC24B | 0.881 | 0.084 |
structurally_consistent (dimer)
|
| AP1M1 | COMT | 0.881 | 0.156 |
structurally_consistent (dimer)
|
| DENND1A | WNK1 | 0.88 | 0.09 | |
| SEC24B | EPS15 | 0.879 | 0.122 | |
| AP1S1 | KIF13A | 0.879 | ||
| ITSN1 | AP1G1 | 0.878 | ||
| SEC24B | AAK1 | 0.878 | 0.156 | |
| BMP2K | DNAJC6 | 0.877 | 0.078 | |
| AP2S1 | AP1S1 | 0.876 | 0.1 | |
| SYNJ1 | STAMBPL1 | 0.874 | 0.134 | |
| SP1 | ZNF106 | 0.874 | 0.12 | |
| AP1S1 | SYNRG | 0.872 | 0.054 | |
| AP1M1 | SEC24B | 0.872 | 0.104 | |
| SYNJ1 | DENND1A | 0.87 | 0.12 | |
| RALBP1 | DNAJC6 | 0.869 | 0.132 | |
| AP2B1 | ZNF106 | 0.868 | 0.156 | |
| CLTCL1 | EPS15 | 0.868 | 0.096 | |
| RALBP1 | GULP1 | 0.867 | 0.064 | |
| TNRC6A | SEC16A | 0.866 | ||
| WNK1 | CLTC | 0.865 | 0.442 | |
| SP1 | AAK1 | 0.863 | 0.02 | |
| NECAP1 | SEC24B | 0.862 | 0.098 | |
| NUMB | CLTC | 0.862 | 0.37 | |
| ZNF106 | CLINT1 | 0.86 | 0.04 | |
| GKN1 | GULP1 | 0.859 | ||
| CLTCL1 | STON2 | 0.858 | 0.082495049505 | |
| AP1G1 | STON2 | 0.857 | 0.086 | |
| CLINT1 | NUMB | 0.857 | 0.138 | |
| WNK1 | AP2A1 | 0.857 | 0.096 | |
| PAAT | BMP2K | 0.855 | 0.118 | |
| PAAT | GKN1 | 0.855 | ||
| FCHO2 | MEA1 | 0.855 | 0.046 | |
| PAAT | NUMB | 0.854 | 0.094 | |
| GULP1 | NUMB | 0.852 | 0.082 | |
| SMAP2 | AAK1 | 0.848 | 0.024 | |
| NECAP2 | REPS1 | 0.847 | 0.04 | |
| NECAP2 | RALBP1 | 0.846 | 0.138 |
mutually_exclusive (Q96CW1)
|
| EPN1 | AP1G1 | 0.845 | 0.092 | |
| EPN1 | SEC24B | 0.845 | 0.132 | |
| CCDC32 | AP1B1 | 0.845 | 0.092 | |
| BMP2K | GULP1 | 0.844 | 0.09 | |
| SEC24B | CLTCL1 | 0.843 | 0.158 | |
| TNRC6A | DENND1A | 0.842 | 0.126 | |
| HIP1 | CLINT1 | 0.839 | 0.136 | |
| AP1B1 | AMPH | 0.839 | 0.192 | |
| SEC24B | SMAP2 | 0.839 | 0.052 | |
| AP1S2 | KIF13A | 0.839 | ||
| EPS15L1 | AP1G1 | 0.838 | 0.274 | |
| AP2B1 | WNK1 | 0.838 | 0.14 | |
| AP2M1 | TNRC6A | 0.836 | 0.246 | |
| SYNJ1 | STON2 | 0.836 | 0.16 | |
| AP1S2 | COMT | 0.832 | 0.092 |
structurally_consistent (Q9BXS5)
|
| TNRC6A | STAMBP | 0.832 | 0.134 | |
| ITSN1 | FCHO2 | 0.831 | ||
| WNK1 | CLTCL1 | 0.831 | 0.214 | |
| AP2A1 | SEC16A | 0.83 | ||
| AP1G1 | AP2A1 | 0.83 | 0.332 | |
| PAAT | GAK | 0.829 | 0.152 | |
| FCHO2 | AP1S2 | 0.826 | 0.054 | |
| FCHO2 | WNK1 | 0.825 | 0.048 | |
| AP2S1 | REPS2 | 0.824 | 0.12 |
structurally_consistent (dimer)
|
| SYNJ1 | AP2A1 | 0.823 | 0.264 | |
| AFTPH | MEA1 | 0.822 | 0.078 | |
| AP1M1 | REPS1 | 0.822 | 0.07 | |
| AP2A1 | CLTC | 0.822 | 0.73 | |
| PAAT | RALBP1 | 0.821 | 0.114 |
mutually_exclusive (Q96CW1)
|
| SEC24B | STON2 | 0.821 | 0.098 | |
| FCHO2 | CLTC | 0.819 | 0.192 | |
| NECAP1 | AP1M2 | 0.819 | 0.04 |
mutually_exclusive (Q9BXS5)
structurally_consistent (dimer) |
| SYNJ1 | BMP2K | 0.817 | 0.156 | |
| AP2S1 | PAAT | 0.817 | 0.104 | |
| AP2A2 | CLINT1 | 0.817 | 0.106 | |
| SYNJ1 | SYNRG | 0.814 | 0.094 | |
| HIP1 | EPS15 | 0.811 | 0.054 | |
| RALBP1 | MEA1 | 0.81 | 0.014 |
mutually_exclusive (Q96CW1)
|
| HIP1 | CLTC | 0.81 | 0.298 | |
| NECAP2 | EPS15 | 0.81 | 0.17 | |
| DENND1A | STAMBP | 0.808 | 0.07 | |
| SYNJ1 | NUMB | 0.808 | 0.196 | |
| SYNJ1 | STAMBP | 0.807 | 0.148 | |
| PAAT | DNAJC6 | 0.806 | 0.074 | |
| NECAP1 | AP1S3 | 0.806 | 0.072 | |
| RUNDC3B | AAK1 | 0.805 | ||
| SMAP2 | BMP2K | 0.798 | 0.048 | |
| AP1M1 | KIF13A | 0.797 | ||
| DNAJC6 | GAK | 0.796 | 0.178 | |
| AP1G1 | AAK1 | 0.796 | 0.092 | |
| ITSN1 | AP1S2 | 0.796 | ||
| NECAP2 | BMP2K | 0.796 | 0.142 | |
| REPS1 | SEC16A | 0.795 | ||
| SYNJ1 | AP1S3 | 0.795 | 0.08 | |
| SYNRG | KIF13A | 0.795 | ||
| KIF13A | AFTPH | 0.795 | ||
| KIF13A | HEATR5B | 0.795 | ||
| PAAT | AP1AR | 0.795 | 0.086 | |
| AP2M1 | STAMBPL1 | 0.794 | 0.098 | |
| AP2B1 | HIP1 | 0.794 | 0.132 | |
| ZNF106 | CLTC | 0.794 | 0.204095238095 | |
| AP1G2 | CLINT1 | 0.794 | 0.046 | |
| AP2M1 | SEC24B | 0.793 | 0.254 | |
| SEC24B | AP2A1 | 0.793 | 0.23 | |
| EPS15L1 | RUNDC3B | 0.793 | ||
| SMAP2 | PIK3C2A | 0.791 | 0.06 | |
| NUMB | SEC16A | 0.791 | ||
| SP1 | GAK | 0.788 | 0.032 | |
| MEA1 | AP2A1 | 0.787 | 0.052 | |
| AP2B1 | AFTPH | 0.787 | 0.226 | |
| AP1S1 | DENND1A | 0.785 | 0.056 | |
| AAK1 | SEC16A | 0.785 | ||
| NECAP2 | MEA1 | 0.783 | 0.03 |
mutually_exclusive (Q96CW1)
|
| KIF13A | AP1G2 | 0.783 | ||
| AP2A2 | MEA1 | 0.781 | 0.085 | |
| SYNRG | HIP1 | 0.781 | 0.073 | |
| NECAP1 | HIP1 | 0.781 | 0.092 | |
| NECAP1 | STAMBPL1 | 0.781 | 0.11 | |
| AP2M1 | STAMBP | 0.779 | 0.136 | |
| SEC24B | WNK1 | 0.778 | 0.128 | |
| SYNJ1 | HIP1 | 0.778 | 0.078 | |
| EPN1 | TNRC6A | 0.778 | 0.126 | |
| AP2A2 | SYNJ1 | 0.778 | 0.118 | |
| TNRC6A | NUMB | 0.777 | 0.104 | |
| HEATR5B | MEA1 | 0.777 | 0.044 | |
| EPN1 | AP1S1 | 0.776 | 0.028 | |
| FCHO2 | GAK | 0.775 | 0.092 | |
| FCHO2 | CLTCL1 | 0.773 | 0.08 | |
| AP2M1 | SEC16A | 0.772 | ||
| EPN1 | CLINT1 | 0.772 | 0.152 | |
| AP1G1 | STAMBPL1 | 0.768 | 0.146 | |
| NECAP2 | DENND1A | 0.768 | 0.122 | |
| AP1B1 | RUNDC3A | 0.766 | 0.06 | |
| FCHO2 | STAMBPL1 | 0.764 | 0.13 | |
| AP2A2 | GKN1 | 0.764 | ||
| FCHO2 | HIP1 | 0.764 | 0.158 | |
| AP2B1 | HEATR5B | 0.762 | 0.166 | |
| NECAP2 | FCHO2 | 0.761 | 0.042 |
structurally_consistent (Q96CW1)
|
| AP2M1 | ZNF106 | 0.76 | 0.1245 | |
| AP1B1 | DENND1A | 0.758 | 0.112 | |
| AP2A2 | GULP1 | 0.755 | 0.160597222222 | |
| CLTCL1 | REPS1 | 0.753 | 0.152 | |
| EPN1 | AP1M1 | 0.753 | 0.132 | |
| SYNJ1 | GULP1 | 0.752 | 0.062 | |
| TNRC6A | CLTCL1 | 0.748 | 0.174 | |
| AP2M1 | REPS2 | 0.747 | 0.138 | |
| EPN1 | CLTCL1 | 0.746 | 0.136 | |
| TNRC6A | EPS15 | 0.746 | 0.098 | |
| AP1M1 | HIP1 | 0.745 | 0.0646666666667 | |
| WNK1 | AP1G1 | 0.744 | 0.078 | |
| STAMBP | AAK1 | 0.741 | 0.07 | |
| AP2B1 | SEC24B | 0.738 | 0.25 | |
| FCHO2 | TNRC6A | 0.736 | 0.104 | |
| CLTCL1 | AAK1 | 0.736 | 0.138 | |
| EPS15 | SEC16A | 0.733 | ||
| ITSN1 | AP1S1 | 0.732 | ||
| NECAP2 | RUNDC3A | 0.729 | 0.07 | |
| PAAT | DENND1A | 0.729 | 0.134 | |
| KIF13A | MEA1 | 0.726 | ||
| CLTC | SEC16A | 0.723 | ||
| AP1AR | DENND1A | 0.722 | 0.092 | |
| AP2B1 | AP1AR | 0.72 | 0.188 | |
| CLINT1 | SEC16A | 0.717 | ||
| AP1G1 | COMT | 0.716 | 0.136 |
structurally_consistent (Q9BXS5)
|
| AP2A2 | STAMBP | 0.715 | 0.218 | |
| AP2M1 | AP1G2 | 0.715 | 0.068 | |
| AP1AR | HIP1 | 0.715 | 0.074 | |
| AP1S1 | BMP2K | 0.714 | 0.034 | |
| MEA1 | AAK1 | 0.713 | 0.03 | |
| AAGAB | AP1G2 | 0.71 | 0.054 |
structurally_consistent (dimer)
|
| WNK1 | CLINT1 | 0.709 | 0.114 | |
| STON2 | SEC16A | 0.706 | ||
| NECAP1 | AP1S2 | 0.705 | 0.124 | |
| EPS15L1 | BMP2K | 0.705 | 0.19 | |
| TNRC6A | SMAP2 | 0.703 | 0.054 | |
| AAGAB | FCHO2 | 0.702 | 0.04 | |
| BMP2K | AP1G1 | 0.7 | 0.086 | |
| EPN1 | AP2A1 | 0.699 | 0.338 | |
| NECAP1 | AP1G2 | 0.699 | 0.056 | |
| SYNRG | REPS1 | 0.688 | 0.124 | |
| AP2B1 | SYNRG | 0.686 | 0.220090909091 | |
| AP2S1 | NUMB | 0.682 | 0.086 | |
| STAMBP | EPS15 | 0.679 | 0.116 | |
| AP2B1 | SEC16A | 0.678 | ||
| AP1B1 | ZNF106 | 0.673 | 0.096 | |
| AP2B1 | CLTCL1 | 0.664 | 0.246 | |
| EPN1 | DNAJC6 | 0.663 | 0.172 | |
| TNRC6A | AP2A1 | 0.662 | 0.216 | |
| AP2A2 | NUMB | 0.661 | 0.1704 | |
| NECAP1 | MEA1 | 0.661 | 0.042 | |
| AP1G2 | COMT | 0.658 | 0.03 | |
| AAGAB | ITSN1 | 0.656 | ||
| REPS2 | BMP2K | 0.652 | 0.134 | |
| AP2S1 | AP1G1 | 0.65 | 0.158 |
structurally_consistent (dimer)
|
| SYNRG | SMAP2 | 0.648 | 0.098 | |
| NECAP1 | TNRC6A | 0.641 | 0.142 | |
| ZNF106 | AAK1 | 0.641 | 0.056 | |
| AP1G1 | NUMB | 0.638 | 0.068 | |
| SYNJ1 | EPS15 | 0.638 | 0.07 | |
| SEC24B | REPS1 | 0.636 | 0.092 | |
| TNRC6A | REPS1 | 0.632 | 0.12 | |
| AP1S2 | EPS15 | 0.629 | 0.072 | |
| MEA1 | BMP2K | 0.627 | 0.026 | |
| AP2A2 | PAAT | 0.627 | 0.172 | |
| AAGAB | AP1AR | 0.625 | 0.126 | |
| RUNDC3B | EPS15 | 0.625 | ||
| AP1S1 | HIP1 | 0.623 | 0.056 | |
| AP1S1 | AFTPH | 0.623 | 0.046 | |
| TNRC6A | WNK1 | 0.62 | 0.148 | |
| SEC24B | NUMB | 0.62 | 0.148 | |
| CCDC32 | ITSN1 | 0.617 | ||
| CCDC32 | AAK1 | 0.617 | 0.072 | |
| AP2S1 | NECAP1 | 0.615 | 0.082 |
structurally_consistent (dimer)
|
| AP1B1 | SMAP2 | 0.613 | 0.102 | |
| AP2S1 | AMPH | 0.613 | 0.092 | |
| HIP1 | AP1G1 | 0.612 | 0.046 | |
| RUNDC3B | AP2A1 | 0.611 | ||
| AP1M1 | SMAP2 | 0.611 | 0.042 | |
| AP1M1 | STON2 | 0.61 | 0.188 | |
| RALBP1 | DENND1A | 0.609 | 0.208 | |
| TNRC6A | HIP1 | 0.608 | 0.062 | |
| AP2B1 | KIF13A | 0.608 | ||
| AP1S1 | SMAP2 | 0.605 | 0.04 | |
| AP2S1 | DENND1A | 0.602 | 0.118 | |
| AP2M1 | RUNDC3B | 0.601 | ||
| MEA1 | REPS1 | 0.601 | 0.05 | |
| AAGAB | HEATR5B | 0.598 | 0.052 | |
| AP2B1 | RUNDC3B | 0.596 | ||
| ITSN2 | STON2 | 0.595 | 0.1 | |
| AP1G1 | CLINT1 | 0.592 | 0.286 | |
| AP1B1 | COMT | 0.592 | 0.16 |
structurally_consistent (Q9BXS5)
|
| SEC24B | HIP1 | 0.592 | 0.03 | |
| RALBP1 | CLTC | 0.591 | 0.24 | |
| AP2S1 | CLTCL1 | 0.59 | 0.118 | |
| EPN1 | AP2M1 | 0.589 | 0.308 | |
| FCHO2 | AP1M1 | 0.586 | 0.114 | |
| RALBP1 | HIP1 | 0.585 | 0.044 | |
| REPS1 | GAK | 0.583 | 0.168 | |
| EPN1 | GKN1 | 0.583 | ||
| AP2M1 | HIP1 | 0.582 | 0.152 | |
| AP2M1 | SMAP2 | 0.579 | 0.124 | |
| AP2A2 | DNAJC6 | 0.579 | 0.166 | |
| SYNRG | MEA1 | 0.578 | 0.034 | |
| NECAP1 | CLTC | 0.577 | 0.257142857143 | |
| EPS15L1 | AP1S2 | 0.574 | 0.072 | |
| RUNDC3B | CLINT1 | 0.573 | ||
| CCDC32 | FCHO2 | 0.572 | 0.052 | |
| SMAP2 | REPS1 | 0.571 | 0.046 | |
| AP1S1 | EPS15 | 0.569 | 0.096 | |
| AAGAB | AFTPH | 0.565 | 0.078 | |
| CCDC32 | EPS15 | 0.563 | 0.026 | |
| NECAP1 | STAMBP | 0.559 | 0.084 | |
| SMAP2 | SEC16A | 0.558 | ||
| RALBP1 | RUNDC3B | 0.558 | ||
| AAGAB | SYNRG | 0.554 | 0.104 | |
| DNAJC6 | HIP1 | 0.554 | 0.148 | |
| FCHO2 | PIK3C2A | 0.553 | 0.17 | |
| AP2A2 | AP1G1 | 0.548 | 0.0923333333333 |
structurally_consistent (dimer)
|
| AFTPH | CLINT1 | 0.539 | 0.168 | |
| AP2M1 | PAAT | 0.535 | 0.1 |
structurally_consistent (dimer)
|
| SMAP2 | HIP1 | 0.53 | 0.052 | |
| WNK1 | SEC16A | 0.528 | ||
| GKN1 | CLINT1 | 0.527 | ||
| SMAP2 | AP1G1 | 0.523 | 0.062 | |
| ITSN2 | AP1S3 | 0.522 | 0.068 | |
| EPN1 | AP1B1 | 0.52 | 0.382 | |
| RALBP1 | STAMBPL1 | 0.519 | 0.082 | |
| AAGAB | AAK1 | 0.517 | 0.066 | |
| AP2S1 | RUNDC3B | 0.517 | ||
| AP2A2 | RUNDC3B | 0.517 | ||
| AP1M1 | WNK1 | 0.513 | 0.144 | |
| AP1B1 | GULP1 | 0.51 | 0.088 | |
| REPS1 | NUMB | 0.509 | 0.094 | |
| NECAP2 | RUNDC3B | 0.502 | ||
| AP1B1 | STAMBPL1 | 0.499 | 0.05 | |
| EPN1 | GULP1 | 0.496 | 0.082 | |
| NECAP1 | KIF13A | 0.496 | ||
| AP1AR | KIF13A | 0.49 | ||
| NECAP2 | STON2 | 0.487 | 0.064 | |
| TNRC6A | GAK | 0.485 | 0.136 | |
| SEC24B | ZNF106 | 0.482 | 0.092 | |
| SEC24B | CLTC | 0.481 | 0.394 | |
| AP1S2 | RALBP1 | 0.48 | 0.118 | |
| CCDC32 | EPS15L1 | 0.475 | 0.202 | |
| AP2A2 | NECAP1 | 0.475 | 0.16 |
mutually_exclusive (P53680)
|
| SMAP2 | CLTCL1 | 0.473 | 0.064 | |
| PIK3C2A | GULP1 | 0.472 | 0.174 | |
| ITSN2 | AP1S1 | 0.471 | 0.074 | |
| RALBP1 | AP1S3 | 0.467 | 0.108 | |
| ITSN2 | AP1S2 | 0.467 | 0.082 | |
| RALBP1 | NUMB | 0.465 | 0.124 | |
| AAGAB | AMPH | 0.464 | 0.164 | |
| SYNJ1 | MEA1 | 0.463 | 0.032 | |
| SYNJ1 | CLINT1 | 0.463 | 0.098 | |
| AP2B1 | SMAP2 | 0.451 | 0.146 | |
| TNRC6A | AAK1 | 0.45 | 0.07 | |
| AP1S3 | AAK1 | 0.44 | 0.042 | |
| AP1AR | CLTC | 0.438 | 0.188 | |
| AP1S1 | GAK | 0.437 | 0.094 | |
| SMAP2 | AP2A1 | 0.437 | 0.14 | |
| SMAP2 | EPS15 | 0.435 | 0.038 | |
| SEC24B | STAMBPL1 | 0.434 | 0.064 | |
| AP1M2 | AP2A1 | 0.433 | 0.07 | |
| AP2M1 | CLTCL1 | 0.432 | 0.202 | |
| AP2M1 | DNAJC6 | 0.43 | 0.244 | |
| EPS15L1 | NECAP1 | 0.43 | 0.158 | |
| NECAP2 | AP1M1 | 0.428 | 0.108 | |
| AP1S3 | GULP1 | 0.428 | 0.04 | |
| AAGAB | EPS15 | 0.427 | 0.038 | |
| ZNF106 | REPS1 | 0.426 | 0.042 | |
| ITSN1 | SYNJ1 | 0.416 | ||
| AAGAB | EPS15L1 | 0.415 | 0.066 | |
| NECAP1 | AFTPH | 0.415 | 0.116 | |
| AP1AR | STAMBPL1 | 0.405 | 0.09 | |
| PAAT | SEC16A | 0.403 | ||
| AP1AR | AP1M2 | 0.402 | 0.05 |
mutually_exclusive (Q9BXS5)
|
| AP2A2 | DENND1A | 0.401 | 0.192 | |
| AP2S1 | STAMBPL1 | 0.397 | 0.086 | |
| AP1S1 | GULP1 | 0.397 | 0.062 | |
| SMAP2 | STON2 | 0.396 | 0.114 | |
| DNAJC6 | REPS1 | 0.396 | 0.182 | |
| AP1G1 | EPS15 | 0.393 | 0.072 |
mutually_exclusive (P53680)
|
| AP2S1 | PIK3C2A | 0.388 | 0.078 | |
| AP1AR | STAMBP | 0.388 | 0.1 | |
| AP1AR | AAK1 | 0.378 | 0.084 | |
| DENND1A | AP1G1 | 0.374 | 0.148 | |
| AP2A2 | AP1G2 | 0.374 | 0.108 | |
| EPN1 | AP2B1 | 0.369 | 0.41 | |
| AP2B1 | PAAT | 0.366 | 0.128 | |
| DNAJC6 | SEC16A | 0.365 | ||
| SYNJ1 | AP1AR | 0.364 | 0.072 | |
| AP1AR | NUMB | 0.364 | 0.092 | |
| AP1S3 | EPS15 | 0.363 | 0.046 | |
| GULP1 | AAK1 | 0.363 | 0.092 | |
| AP1B1 | WNK1 | 0.363 | 0.086 | |
| AP1S2 | BMP2K | 0.362 | 0.042 | |
| AP1S1 | WNK1 | 0.36 | 0.064 | |
| ITSN1 | NECAP1 | 0.36 | ||
| AP2S1 | STAMBP | 0.359 | 0.184 | |
| AP1S3 | COMT | 0.356 | 0.106 | |
| EPN1 | SYNRG | 0.354 | 0.112 | |
| ITSN2 | NECAP1 | 0.353 | 0.092 | |
| NECAP2 | AP1S1 | 0.353 | 0.048 | |
| NECAP1 | GAK | 0.351 | 0.092 |
structurally_consistent (Q10567)
|
| SYNJ1 | SMAP2 | 0.351 | 0.14 | |
| SEC24B | GAK | 0.343 | 0.128 | |
| AP1S1 | HEATR5B | 0.34 | 0.04 | |
| EPS15L1 | AP1S3 | 0.34 | 0.12 | |
| AP2M1 | WNK1 | 0.334 | 0.08 | |
| AP2M1 | AP1M1 | 0.333 | 0.3 | |
| RALBP1 | GAK | 0.333 | 0.17 | |
| AP2S1 | CLTC | 0.331 | 0.566 | |
| MEA1 | DENND1A | 0.33 | 0.1 | |
| FCHO2 | CLINT1 | 0.324 | 0.144 | |
| EPS15L1 | AP1S1 | 0.322 | 0.068 | |
| AP2A2 | AP1M2 | 0.317 | 0.114 | |
| ITSN1 | DENND1A | 0.317 | ||
| NECAP2 | AP1S2 | 0.315 | 0.05 | |
| AP1S2 | CLTC | 0.311 | 0.2 | |
| AP2A2 | STAMBPL1 | 0.309 | 0.276 | |
| EPN1 | SEC16A | 0.307 | ||
| CCDC32 | STON2 | 0.305 | 0.06 | |
| RUNDC3B | REPS1 | 0.303 | ||
| AP1S3 | BMP2K | 0.302 | 0.04 | |
| NECAP1 | HEATR5B | 0.302 | 0.062 | |
| NECAP2 | AP1S3 | 0.3 | 0.054 | |
| ITSN2 | AP1G1 | 0.3 | 0.096 | |
| AP1G2 | STON2 | 0.299 | 0.136 | |
| GULP1 | AP1G1 | 0.297 | 0.126 | |
| ITSN2 | TNRC6A | 0.294 | 0.158 | |
| ITSN1 | AP1G2 | 0.293 | ||
| SYNJ1 | ZNF106 | 0.292 | 0.116 | |
| FCHO2 | STAMBP | 0.289 | 0.114 | |
| NECAP1 | CLTCL1 | 0.288 | 0.122 | |
| ZNF106 | HIP1 | 0.288 | 0.09 | |
| SP1 | BMP2K | 0.287 | 0.024 | |
| SYNJ1 | AP1S2 | 0.287 | 0.098 | |
| AP1S2 | REPS1 | 0.285 | 0.048 | |
| SYNJ1 | PIK3C2A | 0.284 | 0.138 | |
| RALBP1 | SYNRG | 0.281 | 0.102 | |
| AAGAB | AP1M1 | 0.277 | 0.114 | |
| RALBP1 | AP1M2 | 0.277 | 0.056 | |
| AP1M1 | BMP2K | 0.277 | 0.128 | |
| NECAP2 | NUMB | 0.269 | 0.056 | |
| AP1AR | CLINT1 | 0.267 | 0.086 | |
| DENND1A | GULP1 | 0.267 | 0.116 | |
| AP2S1 | AP1G2 | 0.266 | 0.04 | |
| SYNJ1 | SEC24B | 0.265 | 0.128 | |
| SYNRG | WNK1 | 0.263 | 0.158 | |
| AP2S1 | GULP1 | 0.26 | 0.074 | |
| AP1M1 | STAMBPL1 | 0.257 | 0.11 | |
| FCHO2 | AP1G2 | 0.257 | 0.038 | |
| AP2M1 | GAK | 0.256 | 0.198 | |
| CLTCL1 | GULP1 | 0.248 | 0.114 | |
| NECAP1 | SMAP2 | 0.248 | 0.044 | |
| HIP1 | GULP1 | 0.247 | 0.108 | |
| AP1S3 | REPS1 | 0.247 | 0.072 | |
| GULP1 | STON2 | 0.243 | 0.086 | |
| SEC24B | TNRC6A | 0.241 | 0.132 | |
| AAGAB | RALBP1 | 0.24 | 0.034 | |
| ITSN2 | MEA1 | 0.239 | 0.04 | |
| SEC24B | STAMBP | 0.238 | 0.064 | |
| AP1M1 | DENND1A | 0.237 | 0.216 | |
| ITSN2 | GULP1 | 0.236 | 0.048 | |
| AP1S3 | NUMB | 0.233 | 0.046 | |
| SYNRG | STAMBP | 0.232 | 0.068 | |
| SYNRG | STAMBPL1 | 0.232 | 0.086 | |
| SMAP2 | DENND1A | 0.232 | 0.068 | |
| SP1 | NUMB | 0.232 | 0.044 | |
| FCHO2 | SMAP2 | 0.232 | 0.038 | |
| SP1 | DENND1A | 0.232 | 0.072 | |
| AP1S1 | ZNF106 | 0.232 | 0.072 | |
| AP1B1 | STAMBP | 0.232 | 0.128 | |
| ITSN2 | RALBP1 | 0.231 | 0.07 | |
| FCHO2 | GULP1 | 0.23 | 0.068 | |
| NECAP2 | AP1M2 | 0.228 | 0.014 | |
| SMAP2 | CLTC | 0.228 | 0.132 | |
| GULP1 | CLINT1 | 0.225 | 0.176 | |
| AP1M1 | EPS15 | 0.223 | 0.138 | |
| AP1B1 | CLTCL1 | 0.22 | 0.186 | |
| AP1AR | PIK3C2A | 0.22 | 0.1 | |
| NECAP1 | GULP1 | 0.219 | 0.072 | |
| NECAP2 | GULP1 | 0.219 | 0.018 | |
| AP1B1 | TNRC6A | 0.218 | 0.192 | |
| KIF13A | BMP2K | 0.215 | ||
| GKN1 | CLTC | 0.214 | ||
| CCDC32 | REPS1 | 0.209 | 0.094 | |
| AP1S2 | AAK1 | 0.207 | 0.084 | |
| AP1S2 | GULP1 | 0.207 | 0.05 | |
| AP1G2 | EPS15 | 0.206 | 0.05 | |
| EPS15L1 | AP1G2 | 0.206 | 0.04 | |
| AP1B1 | PIK3C2A | 0.205 | 0.148 | |
| ZNF106 | STAMBP | 0.203 | 0.04 | |
| AP2A2 | PIK3C2A | 0.203 | 0.176 | |
| EPN1 | CLTC | 0.201 | 0.328 | |
| EPS15L1 | NUMB | 0.198 | 0.072 | |
| FCHO2 | SYNRG | 0.197 | 0.122 | |
| SP1 | HIP1 | 0.192 | 0.022 | |
| SP1 | STAMBPL1 | 0.192 | 0.068 | |
| AP1S1 | STAMBPL1 | 0.192 | 0.04 | |
| AP1S1 | STAMBP | 0.192 | 0.108 | |
| NECAP1 | PAAT | 0.192 | 0.08 |
mutually_exclusive (Q96CW1)
|
| AP1S2 | NUMB | 0.19 | 0.068 | |
| AP1G1 | STAMBP | 0.189 | 0.282 | |
| KIF13A | AAK1 | 0.188 | ||
| KIF13A | STON2 | 0.188 | ||
| KIF13A | GULP1 | 0.188 | ||
| FCHO2 | KIF13A | 0.188 | ||
| AP1AR | GULP1 | 0.188 | 0.08 | |
| GULP1 | STAMBPL1 | 0.188 | 0.098 | |
| REPS2 | GULP1 | 0.187 | 0.078 | |
| BMP2K | RUNDC3B | 0.187 | ||
| TNRC6A | AP1G1 | 0.187 | 0.13 | |
| EPN1 | AP2A2 | 0.186 | 0.218 | |
| RALBP1 | KIF13A | 0.184 | ||
| AP1B1 | SEC16A | 0.182 | ||
| SYNJ1 | CLTCL1 | 0.18 | 0.168 | |
| AAGAB | NECAP2 | 0.18 | 0.03 |
mutually_exclusive (P53680)
|
| AP1AR | MEA1 | 0.178 | 0.062 | |
| EPS15L1 | DENND1A | 0.178 | 0.202 | |
| SYNJ1 | GAK | 0.176 | 0.156 | |
| KIF13A | REPS1 | 0.173 | ||
| CCDC32 | AP1S3 | 0.172 | 0.064 | |
| CCDC32 | NECAP2 | 0.172 | 0.086 |
mutually_exclusive (P53680)
|
| EPS15L1 | CLINT1 | 0.17 | 0.228 | |
| AP2S1 | WNK1 | 0.169 | 0.05 | |
| AP1M1 | STAMBP | 0.167 | 0.118 | |
| AP1B1 | RUNDC3B | 0.167 | ||
| AP2A2 | HIP1 | 0.166 | 0.106 | |
| KIF13A | NUMB | 0.165 | ||
| CCDC32 | RALBP1 | 0.164 | 0.128 | |
| CCDC32 | BMP2K | 0.164 | 0.13 | |
| CCDC32 | AP1G1 | 0.164 | 0.036 | |
| CLTCL1 | DNAJC6 | 0.161 | 0.118 | |
| AP1M2 | GAK | 0.161 | 0.1 | |
| RALBP1 | AP1G2 | 0.161 | 0.04 | |
| AFTPH | GAK | 0.16 | 0.21 | |
| SYNJ1 | AP1M2 | 0.159 | 0.068 | |
| AFTPH | WNK1 | 0.158 | 0.104 | |
| PAAT | WNK1 | 0.157 | 0.078 | |
| AP2S1 | SMAP2 | 0.154 | 0.034 | |
| AP2S1 | AP1M2 | 0.153 | 0.062 | |
| ITSN1 | RUNDC3A | 0.152 | ||
| AP1S1 | PIK3C2A | 0.151 | 0.062 | |
| MEA1 | GULP1 | 0.151 | 0.026 | |
| SYNJ1 | TNRC6A | 0.151 | 0.176 | |
| AP1M1 | AAK1 | 0.15 | 0.132 | |
| NECAP1 | PIK3C2A | 0.149 | 0.11 | |
| DENND1A | ZNF106 | 0.149 | 0.062 | |
| ITSN2 | NUMB | 0.145 | 0.102 | |
| ITSN2 | KIF13A | 0.144 | ||
| SYNJ1 | KIF13A | 0.144 | ||
| AP1M1 | TNRC6A | 0.143 | 0.176 | |
| CCDC32 | AP1S2 | 0.143 | 0.1 | |
| ITSN1 | GULP1 | 0.142 | ||
| FCHO2 | PAAT | 0.141 | 0.042 | |
| ITSN2 | DENND1A | 0.139 | 0.108 | |
| AP2A2 | AP1M1 | 0.139 | 0.274 | |
| AFTPH | PIK3C2A | 0.138 | 0.068 | |
| AAGAB | STON2 | 0.138 | 0.082 | |
| PAAT | SEC24B | 0.138 | 0.134 | |
| AP2A2 | CLTCL1 | 0.136 | 0.326 | |
| MEA1 | NUMB | 0.135 | 0.05 | |
| AFTPH | STON2 | 0.135 | 0.086 | |
| GULP1 | STAMBP | 0.133 | 0.072 | |
| ITSN2 | BMP2K | 0.131 | 0.1 | |
| SYNRG | CLINT1 | 0.131 | 0.096 | |
| AP1G2 | AP2A1 | 0.131 | 0.152 | |
| REPS2 | DENND1A | 0.131 | 0.11 | |
| AP1M1 | GAK | 0.131 | 0.09 | |
| ITSN2 | SYNJ1 | 0.131 | 0.112 | |
| PAAT | TNRC6A | 0.131 | 0.094 | |
| AP1M1 | NUMB | 0.131 | 0.06 | |
| AP2S1 | AP1AR | 0.13 | 0.108 | |
| AP2A2 | AP1AR | 0.13 | 0.118 | |
| AP1M2 | DENND1A | 0.13 | 0.1 | |
| AP1AR | RALBP1 | 0.13 | 0.22 | |
| AFTPH | REPS1 | 0.129 | 0.11 | |
| AFTPH | EPS15 | 0.129 | 0.068 | |
| AP1M2 | AAK1 | 0.127 | 0.042 | |
| NECAP1 | SEC16A | 0.126 | ||
| AFTPH | HIP1 | 0.126 | 0.068 | |
| SYNRG | EPS15 | 0.126 | 0.14 | |
| AP1AR | AP2A1 | 0.126 | 0.076 | |
| SEC24B | AFTPH | 0.125 | 0.162 | |
| SYNRG | BMP2K | 0.124 | 0.146 | |
| AP2B1 | GULP1 | 0.124 | 0.11 | |
| AP2S1 | HIP1 | 0.123 | 0.066 | |
| TNRC6A | SYNRG | 0.123 | 0.114 | |
| ITSN1 | AP1M1 | 0.123 | ||
| GULP1 | AP2A1 | 0.122 | 0.05 | |
| FCHO2 | ZNF106 | 0.121 | 0.122 | |
| ITSN2 | AAK1 | 0.121 | 0.074 | |
| AP1AR | GAK | 0.12 | 0.148 | |
| AP1M1 | CLTCL1 | 0.12 | 0.144 | |
| AP2S1 | TNRC6A | 0.118 | 0.056 | |
| AP1M2 | HIP1 | 0.117 | 0.128 | |
| AP2S1 | AP1M1 | 0.117 | 0.34 | |
| AP1M1 | AP2A1 | 0.117 | 0.308 | |
| AP1M2 | STAMBPL1 | 0.116 | 0.048 | |
| AP2M1 | AP1AR | 0.116 | 0.12 | |
| GULP1 | CLTC | 0.116 | 0.22 | |
| AAGAB | BMP2K | 0.116 | 0.082 | |
| HEATR5B | EPS15 | 0.114 | 0.064 | |
| EPS15L1 | SYNJ1 | 0.114 | 0.16 | |
| AP2S1 | GAK | 0.113 | 0.114 | |
| NECAP1 | AP1AR | 0.113 | 0.106 | |
| AP2M1 | AP1M2 | 0.112 | 0.028 |
mutually_exclusive (P63010)
|
| SYNRG | NUMB | 0.109 | 0.1 | |
| SP1 | CLINT1 | 0.108 | 0.148 | |
| PAAT | REPS2 | 0.107 | 0.134 | |
| AAGAB | AP1M2 | 0.107 | 0.1 | |
| MEA1 | COMT | 0.105 | 0.036 |
mutually_exclusive (Q9BXS5)
|
| NECAP2 | SYNJ1 | 0.105 | 0.134 | |
| AP1B1 | SEC24B | 0.104 | 0.178 | |
| SYNJ1 | WNK1 | 0.103 | 0.118 | |
| AAGAB | NECAP1 | 0.102 | 0.118 |
mutually_exclusive (P53680)
|
| HEATR5B | STON2 | 0.102 | 0.066 | |
| FCHO2 | HEATR5B | 0.102 | 0.07 | |
| GULP1 | EPS15 | 0.102 | 0.06 | |
| FCHO2 | AFTPH | 0.101 | 0.082 | |
| AFTPH | NUMB | 0.101 | 0.142 | |
| AP1M2 | STON2 | 0.1 | 0.112 | |
| AP1S1 | TNRC6A | 0.098 | 0.124 | |
| AP1G2 | BMP2K | 0.098 | 0.048 | |
| AP1B1 | GAK | 0.097 | 0.342 |
structurally_consistent (dimer)
|
| AAGAB | REPS1 | 0.096 | 0.044 | |
| AP2A2 | CLTC | 0.093 | 0.546 | |
| NECAP2 | AP1G2 | 0.093 | 0.034 | |
| EPS15L1 | AP1M1 | 0.093 | 0.21 | |
| ITSN2 | AFTPH | 0.093 | 0.064 | |
| EPS15L1 | GULP1 | 0.089 | 0.144 | |
| AP1B1 | DNAJC6 | 0.089 | 0.148 | |
| ITSN1 | AFTPH | 0.087 | ||
| AP2A2 | COMT | 0.087 | 0.27 | |
| AP2B1 | DNAJC6 | 0.086 | 0.248 | |
| AP1M2 | STAMBP | 0.086 | 0.0740970873786 | |
| GULP1 | GAK | 0.086 | 0.062 | |
| AP1M2 | GULP1 | 0.084 | 0.066 | |
| AP1M2 | NUMB | 0.083 | 0.028 | |
| AP1M2 | REPS1 | 0.083 | 0.066 | |
| PAAT | STON2 | 0.082 | 0.096 | |
| EPN1 | ZNF106 | 0.082 | 0.07 | |
| AP1AR | REPS1 | 0.082 | 0.072 | |
| TNRC6A | RALBP1 | 0.082 | 0.168 | |
| REPS2 | CLINT1 | 0.081 | 0.18 | |
| HEATR5B | BMP2K | 0.08 | 0.162 | |
| AP1S2 | REPS2 | 0.08 | 0.086 | |
| REPS2 | AP1G1 | 0.08 | 0.094 |
mutually_exclusive (P53680)
|
| SP1 | SMAP2 | 0.08 | 0.016 | |
| AP1G1 | CLTC | 0.079 | 0.896 | |
| ITSN1 | GAK | 0.079 | ||
| AP2M1 | AFTPH | 0.078 | 0.244 | |
| AP1G1 | GAK | 0.078 | 0.16 | |
| SYNRG | STON2 | 0.077 | 0.06 | |
| EPN1 | AP2S1 | 0.076 | 0.29 | |
| AAGAB | KIF13A | 0.076 | ||
| SYNJ1 | AMPH | 0.076 | 0.198 | |
| AP1AR | BMP2K | 0.076 | 0.112 | |
| NECAP2 | KIF13A | 0.076 | ||
| AP2A1 | COMT | 0.076 | 0.128 | |
| ITSN1 | AP1M2 | 0.076 | ||
| AP1M2 | SEC16A | 0.075 | ||
| SYNJ1 | AFTPH | 0.075 | 0.112 | |
| AP1G2 | REPS1 | 0.075 | 0.044 | |
| AP1AR | CLTCL1 | 0.074 | 0.13 | |
| RALBP1 | AFTPH | 0.074 | 0.224 | |
| AP2M1 | COMT | 0.074 | 0.242 | |
| SYNRG | DENND1A | 0.074 | 0.048 | |
| REPS2 | KIF13A | 0.073 | ||
| EPS15L1 | HEATR5B | 0.073 | 0.188 | |
| AP1M2 | PIK3C2A | 0.073 | 0.092 | |
| TNRC6A | ZNF106 | 0.073 | 0.136 | |
| AFTPH | COMT | 0.073 | 0.036 | |
| ITSN2 | AP1G2 | 0.073 | 0.044 | |
| AP1G2 | AAK1 | 0.073 | 0.046 | |
| SEC24B | RALBP1 | 0.072 | 0.184 | |
| RALBP1 | CLTCL1 | 0.071 | 0.1152 | |
| AFTPH | AP2A1 | 0.071 | 0.134 | |
| AAGAB | MEA1 | 0.07 | 0.116 | |
| REPS2 | AP1S3 | 0.07 | 0.096 | |
| NECAP1 | REPS2 | 0.07 | 0.104 | |
| ITSN2 | SYNRG | 0.069 | 0.102 | |
| RALBP1 | COMT | 0.069 | 0.0961333333333 | |
| RALBP1 | HEATR5B | 0.069 | 0.162 | |
| FCHO2 | REPS2 | 0.068 | 0.056 | |
| AP1S1 | REPS2 | 0.068 | 0.074 | |
| REPS2 | STON2 | 0.068 | 0.084 | |
| AP2S1 | HEATR5B | 0.068 | 0.1 | |
| FCHO2 | AP1M2 | 0.068 | 0.034 | |
| SYNRG | AP2A1 | 0.068 | 0.21332 | |
| REPS2 | MEA1 | 0.067 | 0.082 | |
| SYNJ1 | REPS2 | 0.066 | 0.052 | |
| AP1B1 | CLTC | 0.066 | 0.677 | |
| SYNRG | COMT | 0.066 | 0.076 | |
| EPS15L1 | AFTPH | 0.065 | 0.222 | |
| HEATR5B | AP2A1 | 0.064 | 0.198 | |
| AP1AR | SEC16A | 0.064 | ||
| AP1M2 | EPS15 | 0.064 | 0.122 | |
| EPS15L1 | AP1M2 | 0.064 | 0.11 | |
| EPN1 | AP1AR | 0.064 | 0.042 | |
| ITSN1 | NUMB | 0.064 | ||
| AP2B1 | REPS2 | 0.063 | 0.14 | |
| SP1 | STON2 | 0.063 | 0.04 | |
| ZNF106 | AP1G1 | 0.063 | 0.096 | |
| SP1 | CLTCL1 | 0.063 | 0.042 | |
| AP1S1 | CLTCL1 | 0.063 | 0.124 | |
| NECAP2 | COMT | 0.062 | 0.048 | |
| SYNJ1 | SEC16A | 0.062 | ||
| SYNJ1 | AP1G2 | 0.061 | 0.042 | |
| AP2A2 | AFTPH | 0.061 | 0.148 | |
| EPN1 | SP1 | 0.06 | 0.042 | |
| SP1 | PIK3C2A | 0.06 | 0.04 | |
| AP2S1 | SEC16A | 0.059 | ||
| ITSN2 | HIP1 | 0.059 | 0.066 | |
| AP2A2 | GAK | 0.059 | 0.246 | |
| RALBP1 | WNK1 | 0.057 | 0.27 | |
| PIK3C2A | AP1G1 | 0.057 | 0.092 | |
| AAGAB | CLINT1 | 0.057 | 0.068 | |
| EPN1 | ITSN2 | 0.057 | 0.034 | |
| EPN1 | AP1S2 | 0.056 | 0.086 | |
| AP2S1 | KIF13A | 0.055 | ||
| NECAP1 | COMT | 0.055 | 0.036 | |
| SYNRG | PIK3C2A | 0.055 | 0.062 | |
| KIF13A | DENND1A | 0.055 | ||
| AP2A2 | REPS2 | 0.054 | 0.182 | |
| AP1M1 | ZNF106 | 0.053 | 0.154 | |
| AP1S2 | DENND1A | 0.053 | 0.108 | |
| ITSN2 | COMT | 0.051 | 0.07 | |
| STON2 | COMT | 0.05 | 0.216 | |
| SYNRG | AAK1 | 0.05 | 0.098 | |
| ITSN1 | KIF13A | 0.05 | ||
| ITSN1 | RUNDC3B | 0.05 | ||
| CCDC32 | AP1G2 | 0.05 | 0.06 | |
| HEATR5B | COMT | 0.05 | 0.028 | |
| NECAP1 | ZNF106 | 0.049 | 0.088 | |
| AP2A2 | KIF13A | 0.049 | ||
| AP1M1 | CLINT1 | 0.049 | 0.186 | |
| ITSN2 | HEATR5B | 0.048 | 0.084 | |
| AP2S1 | AFTPH | 0.048 | 0.114 | |
| ITSN1 | HEATR5B | 0.047 | ||
| AP2B1 | SP1 | 0.047 | 0.126 | |
| AP1M1 | CLTC | 0.046 | 0.536 | |
| AP1S3 | DENND1A | 0.046 | 0.068 | |
| EPN1 | REPS2 | 0.045 | 0.132 | |
| EPN1 | KIF13A | 0.045 | ||
| AP1G2 | NUMB | 0.045 | 0.052 | |
| SEC24B | SYNRG | 0.045 | 0.13 | |
| NECAP2 | PIK3C2A | 0.045 | 0.05 | |
| EPS15L1 | KIF13A | 0.045 | ||
| REPS2 | NUMB | 0.044 | 0.108 | |
| KIF13A | EPS15 | 0.044 | ||
| KIF13A | AP2A1 | 0.044 | ||
| AP2S1 | ZNF106 | 0.044 | 0.084 | |
| SYNJ1 | CLTC | 0.044 | 0.354 | |
| AP1B1 | REPS2 | 0.043 | 0.164 | |
| CCDC32 | AP1S1 | 0.043 | 0.06 | |
| HEATR5B | CLINT1 | 0.042 | 0.164 | |
| AP1M2 | BMP2K | 0.042 | 0.104 | |
| ITSN1 | SEC24B | 0.042 | ||
| SYNJ1 | HEATR5B | 0.042 | 0.086 | |
| SYNRG | SEC16A | 0.04 | ||
| EPN1 | NECAP2 | 0.04 | 0.058 | |
| FCHO2 | COMT | 0.039 | 0.058 | |
| AMPH | CLINT1 | 0.038 | 0.09 | |
| HEATR5B | NUMB | 0.038 | 0.05 | |
| ITSN2 | REPS1 | 0.037 | 0.042 | |
| CLTC | COMT | 0.037 | 0.472 | |
| MEA1 | CLTC | 0.037 | 0.186 | |
| AP2A2 | HEATR5B | 0.037 | 0.282818181818 | |
| AP1M1 | GULP1 | 0.036 | 0.112 | |
| AFTPH | BMP2K | 0.036 | 0.154 | |
| RALBP1 | ZNF106 | 0.036 | 0.104 | |
| AP2S1 | COMT | 0.036 | 0.078 | |
| REPS2 | EPS15 | 0.036 | 0.186 | |
| AAGAB | CLTC | 0.035 | 0.222 | |
| AFTPH | AAK1 | 0.035 | 0.112 | |
| AP2S1 | SYNRG | 0.034 | 0.104 | |
| EPN1 | AP1S3 | 0.034 | 0.042 | |
| AFTPH | DENND1A | 0.033 | 0.096 | |
| AP1S1 | CLTC | 0.032 | 0.342 | |
| AP1M1 | DNAJC6 | 0.032 | 0.328 | |
| AFTPH | CLTC | 0.032 | 0.196 | |
| NUMB | COMT | 0.032 | 0.018 | |
| CLTCL1 | AP1G1 | 0.031 | 0.16 | |
| DNAJC6 | EPS15 | 0.031 | 0.078 | |
| AP1M2 | RUNDC3A | 0.031 | ||
| ITSN1 | REPS2 | 0.031 | ||
| AP1M1 | PIK3C2A | 0.03 | 0.118 | |
| SYNJ1 | COMT | 0.03 | 0.042 | |
| AP2A2 | SYNRG | 0.03 | 0.114428571429 | |
| EPN1 | AAGAB | 0.03 | 0.038 | |
| AP1M2 | WNK1 | 0.03 | 0.046 | |
| DNAJC6 | AP1G1 | 0.03 | 0.32 | |
| ITSN2 | NECAP2 | 0.029 | 0.07 | |
| AP1G2 | CLTC | 0.029 | 0.145 | |
| SP1 | AP1M2 | 0.029 | 0.034 | |
| AP2S1 | DNAJC6 | 0.029 | 0.13 | |
| AP1M2 | CLINT1 | 0.029 | 0.048 | |
| REPS2 | AP2A1 | 0.028 | 0.15 | |
| ITSN1 | COMT | 0.028 | ||
| MEA1 | CLINT1 | 0.028 | 0.048 | |
| SP1 | SYNRG | 0.027 | 0.19 | |
| SP1 | SEC16A | 0.026 | ||
| AP1M2 | SMAP2 | 0.026 | 0.042 | |
| SYNRG | ZNF106 | 0.026 | 0.064 | |
| HEATR5B | SEC16A | 0.025 | ||
| ITSN2 | GAK | 0.025 | 0.094 | |
| HEATR5B | REPS1 | 0.025 | 0.036 | |
| SP1 | EPS15 | 0.025 | 0.066 | |
| AP2M1 | SYNRG | 0.025 | 0.16 | |
| AP1S3 | SEC16A | 0.024 | ||
| ITSN2 | CCDC32 | 0.024 | 0.05 | |
| PAAT | ZNF106 | 0.023 | 0.098 | |
| SP1 | CLTC | 0.023 | 0.196 | |
| EPS15L1 | SEC24B | 0.023 | 0.156 | |
| AP1B1 | PAAT | 0.022 | 0.13 | |
| AP2M1 | HEATR5B | 0.022 | 0.11 | |
| SYNRG | CLTCL1 | 0.022 | 0.064 | |
| AP2A2 | ZNF106 | 0.022 | 0.204597222222 | |
| AP1G2 | PIK3C2A | 0.022 | 0.056 | |
| ITSN1 | CLINT1 | 0.022 | ||
| HEATR5B | PIK3C2A | 0.022 | 0.098 | |
| AFTPH | GULP1 | 0.022 | 0.036 | |
| AP2A2 | SMAP2 | 0.021 | 0.144 | |
| GKN1 | AP2A1 | 0.021 | ||
| AP1B1 | GKN1 | 0.021 | ||
| REPS2 | SYNRG | 0.021 | 0.184 | |
| KIF13A | SEC16A | 0.02 | ||
| ITSN2 | AAGAB | 0.02 | 0.042 | |
| HEATR5B | CLTC | 0.02 | 0.244 | |
| GULP1 | SEC16A | 0.02 | ||
| AP1M1 | SEC16A | 0.02 | ||
| ITSN2 | AP1M1 | 0.02 | 0.096 | |
| ITSN2 | REPS2 | 0.019 | 0.126 | |
| AP2A2 | SEC16A | 0.019 | ||
| SMAP2 | COMT | 0.018 | 0.032 | |
| NECAP2 | REPS2 | 0.018 | 0.076 | |
| RALBP1 | SEC16A | 0.018 | ||
| DNAJC6 | AP2A1 | 0.018 | 0.172 | |
| AP1G2 | SEC16A | 0.017 | ||
| AP1M2 | DNAJC6 | 0.017 | 0.066 | |
| AP1G1 | SEC16A | 0.017 | ||
| TNRC6A | AFTPH | 0.017 | 0.122 | |
| PAAT | EPS15 | 0.017 | 0.052 | |
| AP1M1 | PAAT | 0.017 | 0.106 | |
| REPS1 | COMT | 0.016 | 0.078 | |
| AP1S3 | ZNF106 | 0.016 | 0.068 | |
| AAGAB | COMT | 0.016 | 0.052 | |
| ITSN2 | WNK1 | 0.016 | 0.1 | |
| EPN1 | AFTPH | 0.016 | 0.204 | |
| AP2S1 | GKN1 | 0.016 | ||
| SEC24B | MEA1 | 0.016 | 0.068 | |
| ITSN1 | PIK3C2A | 0.016 | ||
| AP1S3 | CLTC | 0.015 | 0.234 | |
| EPS15L1 | REPS2 | 0.015 | 0.202 | |
| AP1S2 | HIP1 | 0.015 | 0.084 | |
| EPN1 | COMT | 0.015 | 0.038 | |
| AMPH | CLTC | 0.015 | 0.31 | |
| CLTCL1 | COMT | 0.015 | 0.1 | |
| REPS2 | AP1G2 | 0.015 | 0.04 | |
| AP1G2 | GULP1 | 0.015 | 0.038 | |
| TNRC6A | DNAJC6 | 0.015 | 0.158 | |
| ITSN2 | SEC24B | 0.015 | 0.168 | |
| NECAP2 | CLINT1 | 0.015 | 0.084 | |
| EPN1 | AP1M2 | 0.014 | 0.062 | |
| EPN1 | MEA1 | 0.014 | 0.044 | |
| SEC24B | AP1S3 | 0.014 | 0.136 | |
| REPS2 | WNK1 | 0.014 | 0.114 | |
| PAAT | AP1G1 | 0.014 | 0.172 | |
| EPS15L1 | SYNRG | 0.014 | 0.116 | |
| AP1S2 | PIK3C2A | 0.014 | 0.048 | |
| EPS15 | COMT | 0.014 | 0.038 | |
| ITSN1 | HIP1 | 0.013 | ||
| AP1S1 | SEC16A | 0.013 | ||
| EPN1 | ITSN1 | 0.013 | ||
| TNRC6A | COMT | 0.013 | 0.11 | |
| HEATR5B | AAK1 | 0.013 | 0.09 | |
| PAAT | COMT | 0.013 | 0.068 | |
| EPS15L1 | TNRC6A | 0.013 | 0.16 | |
| AMPH | EPS15 | 0.013 | 0.09 | |
| AP2A2 | SEC24B | 0.013 | 0.168 | |
| AP1G2 | GAK | 0.012 | 0.068 | |
| AAGAB | TNRC6A | 0.012 | 0.126 | |
| GKN1 | REPS1 | 0.012 | ||
| SMAP2 | GULP1 | 0.012 | 0.038 | |
| AP1S2 | SMAP2 | 0.012 | 0.054 | |
| SP1 | AP2A1 | 0.012 | 0.084 | |
| KIF13A | PIK3C2A | 0.012 | ||
| ITSN1 | WNK1 | 0.012 | ||
| ITSN2 | PIK3C2A | 0.012 | 0.116 | |
| KIF13A | CLINT1 | 0.011 | ||
| TNRC6A | HEATR5B | 0.011 | 0.102 | |
| ITSN1 | SYNRG | 0.011 | ||
| SP1 | TNRC6A | 0.011 | 0.106 | |
| AAK1 | COMT | 0.011 | 0.038 | |
| REPS2 | HIP1 | 0.011 | 0.056 | |
| ITSN2 | AP1M2 | 0.011 | 0.054 | |
| EPN1 | AP1G2 | 0.011 | 0.038 | |
| TNRC6A | AP1S3 | 0.011 | 0.102 | |
| SP1 | COMT | 0.011 | 0.02 | |
| PAAT | MEA1 | 0.011 | 0.056 |
mutually_exclusive (Q96CW1)
|
| AAGAB | SEC24B | 0.011 | 0.06 | |
| CCDC32 | TNRC6A | 0.01 | 0.124 | |
| AP1M2 | ZNF106 | 0.01 | 0.092 | |
| PAAT | SMAP2 | 0.01 | 0.08 | |
| ITSN2 | SMAP2 | 0.01 | 0.02 | |
| SYNRG | GAK | 0.01 | 0.104 | |
| BMP2K | COMT | 0.01 | 0.046 | |
| SEC24B | AP1S2 | 0.01 | 0.138 | |
| AFTPH | SMAP2 | 0.01 | 0.07 | |
| TNRC6A | RUNDC3A | 0.01 | 0.09 | |
| RUNDC3A | CLTC | 0.01 | 0.154 | |
| ITSN1 | TNRC6A | 0.01 | ||
| ITSN1 | SEC16A | 0.009 | ||
| SYNRG | CLTC | 0.009 | 0.25 | |
| AMPH | COMT | 0.009 | 0.124 | |
| KIF13A | COMT | 0.009 | ||
| MEA1 | ZNF106 | 0.009 | 0.086 | |
| MEA1 | WNK1 | 0.009 | 0.05 | |
| GULP1 | COMT | 0.009 | 0.09 | |
| REPS2 | SMAP2 | 0.008 | 0.068 | |
| NECAP2 | SYNRG | 0.008 | 0.1 | |
| AFTPH | SEC16A | 0.008 | ||
| TNRC6A | MEA1 | 0.008 | 0.132 | |
| FCHO2 | SP1 | 0.008 | 0.042 | |
| EPS15L1 | COMT | 0.008 | 0.09 | |
| REPS2 | PIK3C2A | 0.008 | 0.066 | |
| HEATR5B | WNK1 | 0.008 | 0.06 | |
| REPS2 | GAK | 0.008 | 0.144 | |
| EPS15L1 | SMAP2 | 0.008 | 0.036 | |
| SEC24B | DNAJC6 | 0.008 | 0.166 | |
| TNRC6A | GULP1 | 0.007 | 0.08 | |
| AP2B1 | COMT | 0.007 | 0.172 |
structurally_consistent (Q9BXS5)
|
| SEC24B | SP1 | 0.007 | 0.03 | |
| AP2A2 | SP1 | 0.007 | 0.122 | |
| NECAP2 | CLTCL1 | 0.007 | 0.078 | |
| AP1M2 | COMT | 0.007 | 0.084 | |
| AP1M2 | CLTC | 0.007 | 0.136325 | |
| PAAT | AP1M2 | 0.007 | 0.078 | |
| AP2B1 | GKN1 | 0.006 | ||
| KIF13A | GAK | 0.006 | ||
| SEC24B | GULP1 | 0.006 | 0.09 | |
| RUNDC3A | SEC16A | 0.006 | ||
| SEC24B | AP1G2 | 0.006 | 0.018 | |
| STAMBP | COMT | 0.006 | 0.05 | |
| ITSN2 | SEC16A | 0.006 | ||
| NECAP2 | ZNF106 | 0.006 | 0.04 | |
| NECAP2 | AFTPH | 0.006 | 0.046 | |
| KIF13A | SMAP2 | 0.006 | ||
| WNK1 | GULP1 | 0.006 | 0.07 | |
| SYNRG | GULP1 | 0.006 | 0.09 | |
| AFTPH | ZNF106 | 0.006 | 0.05 | |
| AP1S2 | WNK1 | 0.006 | 0.056 | |
| SEC24B | HEATR5B | 0.006 | 0.146 | |
| KIF13A | WNK1 | 0.006 | ||
| REPS2 | CLTC | 0.006 | 0.242 | |
| ITSN1 | SMAP2 | 0.006 | ||
| AP2S1 | SEC24B | 0.006 | 0.122 | |
| TNRC6A | REPS2 | 0.006 | 0.102 | |
| SYNJ1 | SP1 | 0.006 | 0.038 | |
| AP1B1 | SP1 | 0.006 | 0.052 | |
| SP1 | REPS1 | 0.006 | 0.052 | |
| ITSN1 | SP1 | 0.006 | ||
| GAK | COMT | 0.005 | 0.03 | |
| MEA1 | CLTCL1 | 0.005 | 0.08 | |
| HEATR5B | GAK | 0.005 | 0.192 | |
| ITSN2 | ZNF106 | 0.005 | 0.106 | |
| REPS2 | AFTPH | 0.005 | 0.21 | |
| AP1S2 | GAK | 0.005 | 0.13 | |
| HEATR5B | SMAP2 | 0.005 | 0.042 | |
| TNRC6A | AP1G2 | 0.005 | 0.056 | |
| SEC24B | REPS2 | 0.005 | 0.148 | |
| DNAJC6 | COMT | 0.005 | 0.228 | |
| MEA1 | SEC16A | 0.005 | ||
| REPS2 | SEC16A | 0.005 | ||
| TNRC6A | KIF13A | 0.005 | ||
| AP1S2 | SEC16A | 0.005 | ||
| EPS15L1 | ZNF106 | 0.004 | 0.122 | |
| EPS15L1 | CLTCL1 | 0.004 | 0.312 | |
| CCDC32 | COMT | 0.004 | 0.032 | |
| NECAP2 | STAMBP | 0.004 | 0.164 | |
| NECAP2 | WNK1 | 0.004 | 0.02 | |
| EPS15L1 | PIK3C2A | 0.004 | 0.066 | |
| EPS15L1 | CLTC | 0.004 | 0.624 | |
| AP1M2 | CLTCL1 | 0.004 | 0.106 | |
| ITSN1 | CLTCL1 | 0.004 | ||
| CCDC32 | CLTC | 0.004 | 0.222 | |
| AP2A2 | TNRC6A | 0.004 | 0.216597222222 | |
| CCDC32 | SEC16A | 0.004 | ||
| SEC16A | COMT | 0.004 | ||
| AP2M1 | SP1 | 0.004 | 0.038 | |
| NECAP2 | GAK | 0.004 | 0.086 | |
| NECAP2 | SMAP2 | 0.004 | 0.054 | |
| ITSN1 | PAAT | 0.003 | ||
| EPS15L1 | WNK1 | 0.003 | 0.176 | |
| CCDC32 | SEC24B | 0.003 | 0.126 | |
| GKN1 | SEC16A | 0.003 | ||
| EPS15L1 | SP1 | 0.003 | 0.074 | |
| ITSN2 | CLINT1 | 0.003 | 0.074 | |
| ITSN1 | ZNF106 | 0.003 | ||
| EPS15L1 | STAMBPL1 | 0.003 | 0.06 | |
| EPS15L1 | GAK | 0.003 | 0.166 | |
| EPS15L1 | PAAT | 0.003 | 0.164 | |
| SEC24B | KIF13A | 0.003 | ||
| AAGAB | SEC16A | 0.003 | ||
| EPN1 | EPS15L1 | 0.003 | 0.288 | |
| SEC24B | AP1M2 | 0.002 | 0.182533333333 | |
| EPS15L1 | HIP1 | 0.002 | 0.07 | |
| NECAP2 | TNRC6A | 0.002 | 0.098 | |
| AP2A2 | WNK1 | 0.002 | 0.242 | |
| AP1S2 | TNRC6A | 0.002 | 0.074 | |
| CLINT1 | COMT | 0.002 | 0.174 | |
| NECAP2 | CLTC | 0.002 | 0.202 | |
| NECAP2 | SEC24B | 0.002 | 0.1 | |
| NECAP2 | SEC16A | 0.002 | ||
| KIF13A | CLTC | 0.002 | ||
| SEC24B | COMT | 0.001 | 0.084 | |
| EPS15L1 | SEC16A | 0.001 | ||
| TNRC6A | AP1M2 | 0.001 | 0.062 | |
| ITSN1 | CLTC | 0.001 | ||
| ITSN2 | CLTC | 0.0 | 0.182 |
Related Complexes