hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12922.1
Complex Portal: CPX-17047
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MT1A | Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA) | 5 | UniProt NCBI |
| MT2A | Metallothionein-2 (MT-2) (Metallothionein-2A) (Metallothionein-II) (MT-II) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5661231 | 2.56314262819e-05 | 1.0 | MT1A MT2A | Metallothioneins bind metals |
| REAC:R-HSA-5660526 | 3.58839967947e-05 | 1.0 | MT1A MT2A | Response to metal ions |
| WP:WP3529 | 0.000149398593408 | 1.0 | MT1A MT2A | Zinc homeostasis |
| KEGG:04978 | 0.000175737839726 | 1.0 | MT1A MT2A | Mineral absorption |
| WP:WP3286 | 0.000402652619272 | 1.0 | MT1A MT2A | Copper homeostasis |
| GO:0010273 | 0.0131096201623 | 1.0 | MT1A MT2A | detoxification of copper ion |
| GO:1990169 | 0.0131096201623 | 1.0 | MT1A MT2A | stress response to copper ion |
| GO:0071280 | 0.0257510396046 | 1.0 | MT1A MT2A | cellular response to copper ion |
| GO:0071294 | 0.0257510396046 | 1.0 | MT1A MT2A | cellular response to zinc ion |
| GO:0097501 | 0.0257510396046 | 1.0 | MT1A MT2A | stress response to metal ion |
| GO:0061687 | 0.0309012475255 | 1.0 | MT1A MT2A | detoxification of inorganic compound |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MT1A | MT2A | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MT1A | huMAP3_03455.1 huMAP3_10041.1 huMAP3_12759.1 huMAP3_12922.1 huMAP3_13125.1 |
| MT2A | huMAP3_08213.1 huMAP3_10041.1 huMAP3_11755.1 huMAP3_12759.1 huMAP3_12922.1 huMAP3_13125.1 |