hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12934.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PEX7 | Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7) | 5 | UniProt NCBI |
| PEX13 | Peroxisomal membrane protein PEX13 (Peroxin-13) | 5 | UniProt NCBI |
| SPX | Spexin (NPQ) (Neuropeptide Q) (Spexin hormone) [Cleaved into: Spexin-1; Spexin-2 (NPQ 53-70)] | 5 | UniProt NCBI |
| C6orf226 | Uncharacterized protein C6orf226 | 2 | UniProt NCBI |
| ACAA1 | 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Acetyl-CoA acyltransferase) (EC 2.3.1.9) (Beta-ketothiolase) (Peroxisomal 3-oxoacyl-CoA thiolase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04146 | 3.86379510922e-05 | 0.6 | PEX7 ACAA1 PEX13 | Peroxisome |
| REAC:R-HSA-9033241 | 5.3727974474e-05 | 0.6 | PEX7 ACAA1 PEX13 | Peroxisomal protein import |
| REAC:R-HSA-9609507 | 0.0012622367962 | 0.6 | PEX7 ACAA1 PEX13 | Protein localization |
| HP:0010571 | 0.00582689447108 | 0.4 | PEX7 PEX13 | Elevated circulating phytanic acid concentration |
| HP:0010965 | 0.00582689447108 | 0.4 | PEX7 PEX13 | Abnormal circulating phytanic acid concentration |
| HP:0010964 | 0.00768171284681 | 0.4 | PEX7 PEX13 | Abnormal circulating long-chain fatty-acid concentration |
| HP:0010655 | 0.0316815705386 | 0.4 | PEX7 PEX13 | Epiphyseal stippling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| C6orf226 | PEX7 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| C6orf226 | ACAA1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PEX7 | PEX13 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ACAA1 | PEX7 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| C6orf226 | PEX13 | 0.921 | bioplex_WMM bioplex3_WMM WMM_only | |
| ACAA1 | SPX | 0.912 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ACAA1 | PEX13 | 0.027 | 0.11 | bioplex3_WMM WMM_only |
Related Complexes