hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_12963.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
TLK1	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)	5	UniProt NCBI
CDIN1	CDAN1-interacting nuclease 1 (Protein HH114)	5	UniProt NCBI
PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)	5	UniProt NCBI
UBN2	Ubinuclein-2	3	UniProt NCBI
ASF1A	Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA)	5	UniProt NCBI
PAN3	PAN2-PAN3 deadenylation complex subunit PAN3 (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 3) (PAN deadenylation complex subunit 3)	5	UniProt NCBI
HIRA	Protein HIRA (TUP1-like enhancer of split protein 1)	5	UniProt NCBI
CDAN1	Codanin-1	5	UniProt NCBI
SPATA1	Spermatogenesis-associated protein 1 (Sperm-specific protein SP-2)	3	UniProt NCBI
ASF1B	Histone chaperone ASF1B (Anti-silencing function protein 1 homolog B) (hAsf1) (hAsf1b) (CCG1-interacting factor A-II) (CIA-II) (hCIA-II)	5	UniProt NCBI
KRT18	Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18)	5	UniProt NCBI
TLK2	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)	5	UniProt NCBI
CABIN1	Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN)	5	UniProt NCBI
CADPS	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1)	5	UniProt NCBI
UBN1	Ubinuclein-1 (HIRA-binding protein) (Protein VT4) (Ubiquitously expressed nuclear protein)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:7382	1.4600392795e-07	0.214285714286	HIRA UBN1 CABIN1	Prohibitin-HIRA complex
CORUM:7383	1.4600392795e-07	0.214285714286	HIRA UBN1 CABIN1	OGT-HIRA complex
REAC:R-HSA-2559584	2.00767838619e-07	0.285714285714	HIRA UBN1 ASF1A CABIN1	Formation of Senescence-Associated Heterochromatin Foci (SAHF)
CORUM:2235	3.64803730192e-07	0.214285714286	HIRA ASF1A ASF1B	ASF1-interacting protein complex
CORUM:1150	1.27537161256e-06	0.214285714286	HIRA ASF1A ASF1B	Histone H3.3 complex
GO:0006325	0.000105772875477	0.571428571429	HIRA CDAN1 ASF1B CABIN1 TLK2 TLK1 UBN1 ASF1A	chromatin organization
REAC:R-HSA-2559586	0.000109566656952	0.285714285714	HIRA UBN1 ASF1A CABIN1	DNA Damage/Telomere Stress Induced Senescence
CORUM:6149	0.000133349500201	0.142857142857	ASF1A CDAN1	Codanin-1-Asf1-histone H3.1-histone H4-importin-4 complex, cytosolic
GO:0071824	0.000336291368192	0.571428571429	HIRA CDAN1 ASF1B CABIN1 TLK2 TLK1 UBN1 ASF1A	protein-DNA complex organization
GO:0006334	0.000444169294054	0.357142857143	HIRA CABIN1 UBN1 ASF1A ASF1B	nucleosome assembly
CORUM:2236	0.000665653089703	0.142857142857	ASF1A ASF1B	ASF1-histone containing complex
GO:0034728	0.00116701534358	0.357142857143	HIRA CABIN1 UBN1 ASF1A ASF1B	nucleosome organization
CORUM:1149	0.00124119242179	0.142857142857	ASF1A ASF1B	Histone H3.1 complex
REAC:R-HSA-2559583	0.00508554984912	0.285714285714	HIRA UBN1 ASF1A CABIN1	Cellular Senescence
GO:0065004	0.015440058157	0.357142857143	HIRA CABIN1 UBN1 ASF1A ASF1B	protein-DNA complex assembly
GO:0031251	0.0426062655276	0.142857142857	PAN2 PAN3	PAN complex

Edges

Protein 1	Protein 2	Score	ProteomeHD
ASF1A	HIRA	1.0	0.086
HIRA	ASF1B	1.0	0.054
UBN2	ASF1A	1.0	0.09
CABIN1	ASF1A	1.0	0.032
TLK1	TLK2	1.0	0.122
TLK1	ASF1B	0.999	0.044
TLK1	ASF1A	0.999	0.086
CABIN1	HIRA	0.999	0.252
ASF1A	UBN1	0.999	0.07
ASF1A	PAN3	0.999	0.056
ASF1A	PAN2	0.998	0.068
UBN2	HIRA	0.998	0.266
CABIN1	ASF1B	0.997	0.03
ASF1A	CDAN1	0.997	0.114
UBN2	ASF1B	0.997	0.096
ASF1B	TLK2	0.997	0.038
CABIN1	UBN2	0.997	0.174
ASF1B	UBN1	0.997	0.036
ASF1A	TLK2	0.996	0.038
PAN2	PAN3	0.996	0.19
CDIN1	ASF1A	0.994	0.114
SPATA1	TLK2	0.991
ASF1A	ASF1B	0.991	0.136
CDAN1	ASF1B	0.991	0.088
TLK1	SPATA1	0.991
ASF1B	PAN3	0.983	0.024
CDIN1	ASF1B	0.982	0.044
HIRA	UBN1	0.975	0.404
UBN2	UBN1	0.972	0.094
CADPS	PAN2	0.969
TLK1	HIRA	0.956	0.124
ASF1B	PAN2	0.951	0.032
CADPS	PAN3	0.938
CABIN1	TLK2	0.917	0.062
HIRA	TLK2	0.907	0.154
TLK1	UBN1	0.894	0.158
CABIN1	UBN1	0.884	0.124
UBN1	TLK2	0.82	0.134
TLK2	KRT18	0.812	0.11
UBN2	TLK2	0.809	0.12
TLK1	CABIN1	0.806	0.056
TLK1	UBN2	0.806	0.154
CDIN1	CDAN1	0.802	0.098
TLK1	CDAN1	0.772	0.13
CDAN1	PAN2	0.756	0.09
TLK1	CDIN1	0.72	0.19
CABIN1	PAN2	0.704	0.088
CDAN1	TLK2	0.698	0.076
UBN1	PAN2	0.669	0.066
CABIN1	CDAN1	0.648	0.068
CDAN1	UBN1	0.645	0.04
UBN2	CDAN1	0.634	0.072
CDIN1	UBN1	0.634	0.122
CDAN1	PAN3	0.608	0.096
CDIN1	TLK2	0.583	0.092
CDIN1	PAN2	0.58	0.104
HIRA	PAN2	0.564	0.148
PAN2	TLK2	0.564	0.118
CDIN1	CABIN1	0.563	0.162
CDIN1	UBN2	0.549	0.092
TLK1	PAN2	0.533	0.076
CABIN1	PAN3	0.526	0.216
CDIN1	PAN3	0.525	0.14
TLK1	PAN3	0.525	0.084
UBN1	PAN3	0.511	0.184
HIRA	PAN3	0.461	0.232
HIRA	CDAN1	0.425	0.082
CDIN1	HIRA	0.37	0.084
UBN2	PAN2	0.34	0.134
TLK1	KRT18	0.248	0.160444444444
UBN2	PAN3	0.192	0.098
PAN3	TLK2	0.176	0.16
UBN2	KRT18	0.023	0.2186
CADPS	ASF1A	0.02
ASF1A	KRT18	0.012	0.08
UBN1	KRT18	0.012	0.092
ASF1B	KRT18	0.008	0.066
HIRA	KRT18	0.006	0.218
PAN2	KRT18	0.004	0.206
CDAN1	KRT18	0.003	0.108
CADPS	KRT18	0.003
PAN3	KRT18	0.003	0.212

Related Complexes

Genename	Complexes
TLK1	huMAP3_00115.1 huMAP3_01778.1 huMAP3_01879.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_10933.1 huMAP3_12566.1 huMAP3_12711.1 huMAP3_12963.1
CDIN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11832.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
PAN2	huMAP3_00724.1 huMAP3_05456.1 huMAP3_08143.1 huMAP3_08866.1 huMAP3_09289.1 huMAP3_09764.1 huMAP3_09859.1 huMAP3_11834.1 huMAP3_12015.1 huMAP3_12538.1 huMAP3_12711.1 huMAP3_12963.1 huMAP3_13022.1 huMAP3_15185.1
UBN2	huMAP3_00115.1 huMAP3_00724.1 huMAP3_01912.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11745.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
ASF1A	huMAP3_00115.1 huMAP3_00724.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
PAN3	huMAP3_00724.1 huMAP3_02330.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09764.1 huMAP3_09859.1 huMAP3_11834.1 huMAP3_12015.1 huMAP3_12538.1 huMAP3_12711.1 huMAP3_12963.1 huMAP3_13022.1 huMAP3_15185.1
HIRA	huMAP3_00115.1 huMAP3_00724.1 huMAP3_01912.1 huMAP3_05517.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
CDAN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
SPATA1	huMAP3_01537.1 huMAP3_01778.1 huMAP3_01879.1 huMAP3_05664.1 huMAP3_06772.1 huMAP3_09289.1 huMAP3_10933.1 huMAP3_11465.1 huMAP3_12566.1 huMAP3_12711.1 huMAP3_12963.1
ASF1B	huMAP3_00115.1 huMAP3_00724.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
KRT18	huMAP3_11834.1 huMAP3_12566.1 huMAP3_12711.1 huMAP3_12963.1 huMAP3_13906.1
TLK2	huMAP3_01778.1 huMAP3_01879.1 huMAP3_04345.1 huMAP3_05467.1 huMAP3_06772.1 huMAP3_09289.1 huMAP3_10849.1 huMAP3_10933.1 huMAP3_11834.1 huMAP3_12566.1 huMAP3_12711.1 huMAP3_12963.1
CABIN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_01912.1 huMAP3_05517.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
CADPS	huMAP3_00021.1 huMAP3_05456.1 huMAP3_06486.1 huMAP3_07138.1 huMAP3_10194.1 huMAP3_11834.1 huMAP3_12015.1 huMAP3_12538.1 huMAP3_12711.1 huMAP3_12963.1 huMAP3_13022.1 huMAP3_15185.1
UBN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_01912.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_12963.1