hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_12984.1
Complex Portal: CPX-18404
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FBRSL1 | Fibrosin-1-like protein (AUTS2-like protein) (HBV X-transactivated gene 9 protein) (HBV XAg-transactivated protein 9) | 3 | UniProt NCBI |
| HIPK2 | Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1) | 5 | UniProt NCBI |
| FAM53C | Protein FAM53C | 3 | UniProt NCBI |
| SOWAHB | Ankyrin repeat domain-containing protein SOWAHB (Ankyrin repeat domain-containing protein 56) (Protein sosondowah homolog B) | 3 | UniProt NCBI |
| DIAPH2 | Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) | 5 | UniProt NCBI |
| ZNF703 | Zinc finger protein 703 (Zinc finger elbow-related proline domain protein 1) | 5 | UniProt NCBI |
| RNF169 | E3 ubiquitin-protein ligase RNF169 (EC 2.3.2.27) (RING finger protein 169) (RING-type E3 ubiquitin transferase RNF169) | 5 | UniProt NCBI |
| ZNF503 | Zinc finger protein 503 | 5 | UniProt NCBI |
| SOWAHC | Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C) | 2 | UniProt NCBI |
| DIAPH1 | Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9035034 | 0.000630778022304 | 0.3 | DIAPH2 DIAPH1 SOWAHC | RHOF GTPase cycle |
| HPA:0291161 | 0.0441471986325 | 0.8 | ZNF503 HIPK2 ZNF703 FAM53C DIAPH2 SOWAHB DIAPH1 SOWAHC | liver; cholangiocytes[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF703 | ZNF503 | 0.991 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| SOWAHB | DIAPH2 | 0.991 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SOWAHC | DIAPH1 | 0.98 | 0.128 | hein_WMM bioplex_WMM bioplex3_WMM boldt hein () boldt_WMM | |
| SOWAHB | DIAPH1 | 0.972 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| FAM53C | DIAPH1 | 0.933 | 0.058 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SOWAHC | RNF169 | 0.924 | 0.116 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
| SOWAHC | FBRSL1 | 0.918 | 0.104 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| SOWAHC | SOWAHB | 0.908 |
mutually_exclusive (P61962)
|
bioplex3_WMM WMM_only | |
| HIPK2 | SOWAHB | 0.904 | bioplex3_WMM WMM_only | ||
| SOWAHC | FAM53C | 0.902 | 0.112 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM WMM_only |
| RNF169 | SOWAHB | 0.902 |
mutually_exclusive (P61962)
|
bioplex3_WMM WMM_only | |
| HIPK2 | SOWAHC | 0.902 | bioplex3_WMM WMM_only | ||
| SOWAHB | FBRSL1 | 0.892 |
mutually_exclusive (P61962)
|
bioplex3_WMM WMM_only | |
| FAM53C | SOWAHB | 0.869 |
mutually_exclusive (P61962)
|
bioplex3_WMM WMM_only | |
| RNF169 | DIAPH1 | 0.853 | 0.08 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| ZNF503 | FBRSL1 | 0.836 | 0.094 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
| ZNF703 | SOWAHC | 0.819 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| RNF169 | FBRSL1 | 0.815 | 0.1 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
| ZNF703 | RNF169 | 0.81 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| ZNF703 | FAM53C | 0.809 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF503 | RNF169 | 0.804 | 0.08 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
| ZNF703 | FBRSL1 | 0.802 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| SOWAHC | ZNF503 | 0.76 | 0.064 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| ZNF503 | DIAPH1 | 0.732 | 0.11 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| FAM53C | FBRSL1 | 0.73 | 0.11 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM WMM_only |
| RNF169 | FAM53C | 0.73 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| HIPK2 | RNF169 | 0.73 | bioplex3_WMM WMM_only | ||
| ZNF503 | FAM53C | 0.695 | 0.09 |
mutually_exclusive (P61962)
|
bioplex_WMM bioplex3_WMM WMM_only |
| HIPK2 | FAM53C | 0.675 | bioplex3_WMM WMM_only | ||
| HIPK2 | FBRSL1 | 0.675 | bioplex3_WMM WMM_only | ||
| ZNF503 | SOWAHB | 0.675 |
mutually_exclusive (P61962)
|
bioplex3_WMM WMM_only | |
| ZNF703 | SOWAHB | 0.652 |
mutually_exclusive (P61962)
|
bioplex3_WMM WMM_only | |
| HIPK2 | ZNF503 | 0.631 | bioplex3_WMM WMM_only | ||
| HIPK2 | DIAPH1 | 0.63 | bioplex3_WMM WMM_only | ||
| HIPK2 | ZNF703 | 0.545 | bioplex3_WMM WMM_only | ||
| DIAPH1 | FBRSL1 | 0.455 | 0.13 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| DIAPH1 | DIAPH2 | 0.407 | 0.164 | bioplex3_WMM youn_WMM WMM_only | |
| ZNF703 | DIAPH1 | 0.289 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | ||
| SOWAHC | DIAPH2 | 0.018 | 0.102 | bioplex3_WMM WMM_only |
Related Complexes