hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_12999.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UNKL | Putative E3 ubiquitin-protein ligase UNKL (EC 2.3.2.-) (RING finger protein unkempt-like) (Zinc finger CCCH domain-containing protein 5-like) | 5 | UniProt NCBI |
| KMT2C | Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3) | 5 | UniProt NCBI |
| MEN1 | Menin | 5 | UniProt NCBI |
| CYP4X1 | Cytochrome P450 4X1 (EC 1.14.14.-) (CYPIVX1) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9772755 | 0.0079693038543 | 0.5 | KMT2C MEN1 | Formation of WDR5-containing histone-modifying complexes |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MEN1 | CYP4X1 | 0.973 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| UNKL | MEN1 | 0.943 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| KMT2C | MEN1 | 0.903 | 0.036 | hein_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes