hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13000.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| WDPCP | WD repeat-containing and planar cell polarity effector protein fritz homolog (hFRTZ) (Bardet-Biedl syndrome 15 protein) (WD repeat-containing and planar cell polarity effector protein) | 5 | UniProt NCBI |
| INTU | Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6) | 5 | UniProt NCBI |
| OSBPL9 | Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9) | 5 | UniProt NCBI |
| CPLANE2 | Ciliogenesis and planar polarity effector 2 (REM2- and Rab-like small GTPase 1) | 5 | UniProt NCBI |
| FUZ | Protein fuzzy homolog | 5 | UniProt NCBI |
| OSBPL11 | Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) | 5 | UniProt NCBI |
| MYL4 | Myosin light chain 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali GT-1 isoform) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0001736 | 0.000316805542726 | 0.5 | WDPCP FUZ INTU | establishment of planar polarity |
| GO:0007164 | 0.000316805542726 | 0.5 | WDPCP FUZ INTU | establishment of tissue polarity |
| WP:WP4536 | 0.000413392056955 | 0.5 | WDPCP FUZ CPLANE2 | Genes related to primary cilium development based on CRISPR |
| GO:0001738 | 0.00627357313526 | 0.5 | WDPCP FUZ INTU | morphogenesis of a polarized epithelium |
| HP:0001674 | 0.00711805296098 | 0.333333333333 | WDPCP INTU | Complete atrioventricular canal defect |
| HP:0011802 | 0.0184186741717 | 0.333333333333 | WDPCP INTU | Hamartoma of tongue |
| GO:0042073 | 0.0219369042126 | 0.5 | WDPCP FUZ INTU | intraciliary transport |
| WP:WP5234 | 0.0283311425678 | 0.333333333333 | WDPCP FUZ | Bardet Biedl syndrome |
| GO:0021915 | 0.0309610298034 | 0.5 | WDPCP FUZ INTU | neural tube development |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FUZ | CPLANE2 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | |
| OSBPL9 | OSBPL11 | 0.997 | 0.428 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| FUZ | INTU | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM | |
| FUZ | WDPCP | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| INTU | CPLANE2 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM | |
| OSBPL11 | FUZ | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM | |
| OSBPL9 | FUZ | 0.978 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM | |
| OSBPL11 | MYL4 | 0.857 | 0.01 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| OSBPL9 | MYL4 | 0.746 | 0.016 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| WDPCP | INTU | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | |
| WDPCP | CPLANE2 | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | |
| OSBPL11 | WDPCP | 0.502 | bioplex_WMM bioplex3_WMM WMM_only | |
| OSBPL9 | WDPCP | 0.502 | bioplex_WMM bioplex3_WMM WMM_only | |
| OSBPL11 | CPLANE2 | 0.226 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| OSBPL9 | CPLANE2 | 0.216 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| OSBPL11 | INTU | 0.165 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| OSBPL9 | INTU | 0.165 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
Related Complexes