hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13015.1
Complex Portal: CPX-13658
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZNF726 | Zinc finger protein 726 | 3 | UniProt NCBI |
| TRIM28 | Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28) | 5 | UniProt NCBI |
| ZNF354C | Zinc finger protein 354C (Kidney, ischemia, and developmentally-regulated protein 3) (hKID3) | 5 | UniProt NCBI |
| ZNF333 | Zinc finger protein 333 | 5 | UniProt NCBI |
| ZNF716 | Zinc finger protein 716 | 3 | UniProt NCBI |
| TRIM39 | E3 ubiquitin-protein ligase TRIM39 (EC 2.3.2.27) (RING finger protein 23) (RING-type E3 ubiquitin transferase TRIM39) (Testis-abundant finger protein) (Tripartite motif-containing protein 39) | 5 | UniProt NCBI |
| ZNF311 | Zinc finger protein 311 (Zinc finger protein zfp-31) | 3 | UniProt NCBI |
| ZNF678 | Zinc finger protein 678 | 3 | UniProt NCBI |
| ZNF621 | Zinc finger protein 621 | 3 | UniProt NCBI |
| ZNF718 | Zinc finger protein 718 | 3 | UniProt NCBI |
| ZNF595 | Zinc finger protein 595 | 3 | UniProt NCBI |
| TRIM24 | Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05168 | 3.45500678012e-09 | 0.666666666667 | ZNF726 ZNF718 ZNF311 ZNF354C ZNF621 ZNF716 ZNF595 ZNF333 | Herpes simplex virus 1 infection |
| REAC:R-HSA-212436 | 4.34997038434e-08 | 0.833333333333 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | Generic Transcription Pathway |
| REAC:R-HSA-73857 | 1.29006655752e-07 | 0.833333333333 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | RNA Polymerase II Transcription |
| GO:0000978 | 4.31881287884e-07 | 0.833333333333 | ZNF726 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| REAC:R-HSA-74160 | 4.45489549754e-07 | 0.833333333333 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | Gene expression (Transcription) |
| GO:0000987 | 5.30882171646e-07 | 0.833333333333 | ZNF726 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | cis-regulatory region sequence-specific DNA binding |
| GO:0140110 | 2.0727289059e-06 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | transcription regulator activity |
| GO:0000977 | 2.17876247744e-06 | 0.833333333333 | ZNF726 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO:0000976 | 5.07738422639e-06 | 0.833333333333 | ZNF726 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | transcription cis-regulatory region binding |
| GO:0001067 | 5.12904918905e-06 | 0.833333333333 | ZNF726 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | transcription regulatory region nucleic acid binding |
| GO:0003677 | 7.05654089997e-06 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | DNA binding |
| GO:1990837 | 8.08165106267e-06 | 0.833333333333 | ZNF726 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | sequence-specific double-stranded DNA binding |
| GO:0043565 | 1.63971771851e-05 | 0.833333333333 | ZNF726 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | sequence-specific DNA binding |
| GO:0003690 | 1.68442010149e-05 | 0.833333333333 | ZNF726 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | double-stranded DNA binding |
| GO:0000981 | 8.78220861606e-05 | 0.75 | ZNF726 ZNF718 ZNF311 ZNF354C ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0003700 | 0.000152292825701 | 0.75 | ZNF726 ZNF718 ZNF311 ZNF354C ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | DNA-binding transcription factor activity |
| GO:0006351 | 0.00129352492083 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | DNA-templated transcription |
| GO:0032774 | 0.00145229192484 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | RNA biosynthetic process |
| GO:0003676 | 0.00532200603023 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | nucleic acid binding |
| GO:0034654 | 0.00564313932845 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | nucleobase-containing compound biosynthetic process |
| GO:0018130 | 0.00687055826053 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | heterocycle biosynthetic process |
| GO:0019438 | 0.00694976884025 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | aromatic compound biosynthetic process |
| GO:1901362 | 0.00949722550579 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | organic cyclic compound biosynthetic process |
| GO:0006355 | 0.0231954695221 | 0.833333333333 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | regulation of DNA-templated transcription |
| GO:2001141 | 0.024593100625 | 0.833333333333 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | regulation of RNA biosynthetic process |
| GO:0016070 | 0.0295140519053 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | RNA metabolic process |
| TF:M03825_1 | 0.0470276743302 | 0.333333333333 | ZNF595 ZNF726 ZNF716 ZNF678 | Factor: Gfi1b; motif: YYCAATCWSD; match class: 1 |
| GO:0044271 | 0.0482066228902 | 0.916666666667 | ZNF726 TRIM28 ZNF718 ZNF311 ZNF354C TRIM24 ZNF621 ZNF716 ZNF595 ZNF333 ZNF678 | cellular nitrogen compound biosynthetic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF726 | ZNF716 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ZNF726 | TRIM39 | 0.991 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ZNF333 | TRIM39 | 0.99 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TRIM28 | ZNF718 | 0.988 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ZNF354C | TRIM39 | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TRIM28 | ZNF726 | 0.982 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TRIM28 | ZNF595 | 0.979 | 0.134 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TRIM28 | ZNF354C | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF621 | TRIM39 | 0.978 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TRIM28 | ZNF621 | 0.968 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| TRIM28 | ZNF333 | 0.967 | bioplex3_HEK293 bioplex () bioplex3_WMM youn_WMM bioplex3_HCT116 bioplex_WMM | ||
| TRIM28 | TRIM39 | 0.954 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TRIM39 | TRIM24 | 0.949 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TRIM39 | ZNF311 | 0.944 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TRIM28 | ZNF311 | 0.914 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TRIM28 | TRIM24 | 0.862 | 0.43 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| TRIM24 | ZNF718 | 0.701 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TRIM39 | ZNF718 | 0.676 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ZNF726 | TRIM24 | 0.388 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ZNF716 | TRIM39 | 0.388 | bioplex3_WMM WMM_only | ||
| TRIM28 | ZNF716 | 0.356 | bioplex3_WMM WMM_only | ||
| ZNF716 | TRIM24 | 0.042 | bioplex3_WMM WMM_only |
Related Complexes