hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13021.1
Complex Portal: CPX-17920
Confidence: Medium  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC5A1 | Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter) (Solute carrier family 5 member 1) | 5 | UniProt   NCBI |
| SLC5A9 | Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (hSGLT4) (Solute carrier family 5 member 9) | 5 | UniProt   NCBI |
| CD63 | CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   REAC:R-HSA-189200 | 0.000715513386354 | 0.666666666667 | SLC5A1 SLC5A9 | Cellular hexose transport |
|   WP:WP2884 | 0.00700579973273 | 0.666666666667 | SLC5A1 SLC5A9 | NRF2 pathway |
|   GO:0005412 | 0.00842684400117 | 0.666666666667 | SLC5A1 SLC5A9 | glucose:sodium symporter activity |
|   WP:WP2882 | 0.0351361093338 | 0.666666666667 | SLC5A1 SLC5A9 | Nuclear receptors meta pathway |
|   REAC:R-HSA-5656364 | 0.0498224659464 | 0.333333333333 | SLC5A1 | Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) |
|   CORUM:2153 | 0.0499402709677 | 0.333333333333 | CD63 | ITGAM-ITGB2-CD11 complex |
|   CORUM:2424 | 0.0499402709677 | 0.333333333333 | CD63 | ITGA4-ITGB1-CD63 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  CD63 |  SLC5A9 | 0.919 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  CD63 |  SLC5A1 | 0.815 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| SLC5A1 | huMAP3_02324.1 huMAP3_11165.1 huMAP3_13021.1 huMAP3_14113.1 |
| SLC5A9 | huMAP3_13021.1 |
| CD63 | huMAP3_02201.1 huMAP3_04870.1 huMAP3_05584.1 huMAP3_08689.1 huMAP3_09336.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1 huMAP3_13021.1 |