hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13036.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DBF4 | Protein DBF4 homolog A (Activator of S phase kinase) (Chiffon homolog A) (DBF4-type zinc finger-containing protein 1) | 5 | UniProt NCBI |
| CDC7 | Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1) | 5 | UniProt NCBI |
| IQGAP2 | Ras GTPase-activating-like protein IQGAP2 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:947 | 3.41752350426e-06 | 0.666666666667 | DBF4 CDC7 | CDC7-DBF7 complex |
| WP:WP466 | 0.000973512535349 | 0.666666666667 | DBF4 CDC7 | DNA replication |
| REAC:R-HSA-68962 | 0.00359505378021 | 0.666666666667 | DBF4 CDC7 | Activation of the pre-replicative complex |
| REAC:R-HSA-176187 | 0.00428896488724 | 0.666666666667 | DBF4 CDC7 | Activation of ATR in response to replication stress |
| WP:WP179 | 0.00751610583681 | 0.666666666667 | DBF4 CDC7 | Cell cycle |
| KEGG:04110 | 0.00858640718729 | 0.666666666667 | DBF4 CDC7 | Cell cycle |
| GO:0010571 | 0.0210651876021 | 0.666666666667 | DBF4 CDC7 | positive regulation of nuclear cell cycle DNA replication |
| GO:0033262 | 0.0393180950424 | 0.666666666667 | DBF4 CDC7 | regulation of nuclear cell cycle DNA replication |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| DBF4 | CDC7 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| IQGAP2 | CDC7 | 0.844 | 0.152 | bioplex_WMM bioplex3_WMM boldt WMM_only boldt_WMM |
| IQGAP2 | DBF4 | 0.045 | bioplex3_WMM WMM_only |
Related Complexes