hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13037.1
Complex Portal: CPX-22644
Confidence: Medium  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OSGIN1 | Oxidative stress-induced growth inhibitor 1 (Bone marrow stromal cell-derived growth inhibitor) (BMSC-derived growth inhibitor) (Ovary, kidney and liver protein 38) (huOKL38) (Pregnancy-induced growth inhibitor OKL38) | 5 | UniProt   NCBI |
| RPS6KA6 | Ribosomal protein S6 kinase alpha-6 (S6K-alpha-6) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (p90RSK6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) | 5 | UniProt   NCBI |
| TUBA3E | Tubulin alpha-3E chain (EC 3.6.5.-) (Alpha-tubulin 3E) [Cleaved into: Detyrosinated tubulin alpha-3E chain] | 5 | UniProt   NCBI |
| HUNK | Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V) | 4 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   REAC:R-HSA-437239 | 0.0105688559686 | 0.5 | TUBA3E RPS6KA6 | Recycling pathway of L1 |
|   REAC:R-HSA-438064 | 0.0232149434748 | 0.5 | TUBA3E RPS6KA6 | Post NMDA receptor activation events |
|   REAC:R-HSA-442755 | 0.0321680026233 | 0.5 | TUBA3E RPS6KA6 | Activation of NMDA receptors and postsynaptic events |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  OSGIN1 |  RPS6KA6 | 0.991 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  OSGIN1 |  TUBA3E | 0.984 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
|  RPS6KA6 |  HUNK | 0.866 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
|  RPS6KA6 |  TUBA3E | 0.415 |            |          | bioplex3_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| OSGIN1 | huMAP3_00211.1 huMAP3_01607.1 huMAP3_12655.1 huMAP3_13037.1 |
| RPS6KA6 | huMAP3_00211.1 huMAP3_01607.1 huMAP3_12655.1 huMAP3_13037.1 |
| TUBA3E | huMAP3_01607.1 huMAP3_13037.1 huMAP3_14584.1 |
| HUNK | huMAP3_12655.1 huMAP3_13037.1 |