hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13048.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HBE1 | Hemoglobin subunit epsilon (Epsilon-globin) (Hemoglobin epsilon chain) | 5 | UniProt NCBI |
| CPEB2 | Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (hCPEB-2) | 5 | UniProt NCBI |
| CPEB4 | Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4) | 5 | UniProt NCBI |
| HBG1 | Hemoglobin subunit gamma-1 (Gamma-1-globin) (Hb F Agamma) (Hemoglobin gamma-1 chain) (Hemoglobin gamma-A chain) | 5 | UniProt NCBI |
| CPEB3 | Cytoplasmic polyadenylation element-binding protein 3 (CPE-BP3) (CPE-binding protein 3) (hCPEB-3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:2000766 | 8.06911104389e-05 | 0.6 | CPEB2 CPEB4 CPEB3 | negative regulation of cytoplasmic translation |
| KEGG:04914 | 8.19757737363e-05 | 0.6 | CPEB2 CPEB4 CPEB3 | Progesterone-mediated oocyte maturation |
| GO:0000900 | 0.000115261178119 | 0.6 | CPEB2 CPEB4 CPEB3 | mRNA regulatory element binding translation repressor activity |
| GO:1990124 | 0.000158467845213 | 0.6 | CPEB2 CPEB4 CPEB3 | messenger ribonucleoprotein complex |
| KEGG:04114 | 0.000168183083601 | 0.6 | CPEB2 CPEB4 CPEB3 | Oocyte meiosis |
| GO:0030371 | 0.00249322401434 | 0.6 | CPEB2 CPEB4 CPEB3 | translation repressor activity |
| GO:2000765 | 0.00430818612204 | 0.6 | CPEB2 CPEB4 CPEB3 | regulation of cytoplasmic translation |
| GO:1900247 | 0.00468200720083 | 0.4 | CPEB2 CPEB3 | regulation of cytoplasmic translational elongation |
| GO:1900248 | 0.00468200720083 | 0.4 | CPEB2 CPEB3 | negative regulation of cytoplasmic translational elongation |
| GO:0045900 | 0.0140440992017 | 0.4 | CPEB2 CPEB3 | negative regulation of translational elongation |
| MIRNA:ebv-miR-BART10-3p | 0.0250826699056 | 0.6 | CPEB2 CPEB4 CPEB3 | ebv-miR-BART10-3p |
| GO:0002182 | 0.0280843539964 | 0.4 | CPEB2 CPEB3 | cytoplasmic translational elongation |
| GO:0031721 | 0.0468008499735 | 0.4 | HBG1 HBE1 | hemoglobin alpha binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HBG1 | HBE1 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CPEB4 | HBG1 | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CPEB2 | CPEB4 | 0.983 | 0.156 | bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only |
| CPEB4 | CPEB3 | 0.978 | youn () bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only | |
| CPEB2 | HBG1 | 0.415 | bioplex3_WMM WMM_only | |
| CPEB3 | HBG1 | 0.415 | bioplex3_WMM WMM_only | |
| CPEB2 | CPEB3 | 0.415 | bioplex3_WMM WMM_only |
Related Complexes