hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13049.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
MCOLN1 | Mucolipin-1 (ML1) (MG-2) (Mucolipidin) (Transient receptor potential channel mucolipin 1) (TRPML1) | 5 | UniProt   NCBI |
LY6D | Lymphocyte antigen 6D (Ly-6D) (E48 antigen) | 5 | UniProt   NCBI |
OSGEPL1 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase-like protein 1) (OSGEP-like protein 1) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1) | 5 | UniProt   NCBI |
MCOLN2 | Mucolipin-2 (Transient receptor potential channel mucolipin 2) (TRPML2) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-3295583 | 0.0013924419067 | 0.5 | MCOLN2 MCOLN1 | TRP channels |
  REAC:R-HSA-2672351 | 0.0212029570934 | 0.5 | MCOLN2 MCOLN1 | Stimuli-sensing channels |
  GO:0072345 | 0.0280843539964 | 0.5 | MCOLN2 MCOLN1 | NAADP-sensitive calcium-release channel activity |
  KEGG:04020 | 0.036316189849 | 0.5 | MCOLN2 MCOLN1 | Calcium signaling pathway |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 MCOLN1 |  LY6D | 0.98 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 MCOLN1 |  MCOLN2 | 0.971 |            | bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     WMM_only     |
 LY6D |  MCOLN2 | 0.971 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 MCOLN2 |  OSGEPL1 | 0.904 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 MCOLN1 |  OSGEPL1 | 0.095 | 0.06           | bioplex3_WMM     WMM_only     |
Related Complexes
Genename | Complexes |
---|---|
MCOLN1 | huMAP3_01319.1 huMAP3_10268.1 huMAP3_11767.1 huMAP3_13049.1 |
LY6D | huMAP3_01319.1 huMAP3_10268.1 huMAP3_11767.1 huMAP3_12044.1 huMAP3_13049.1 |
OSGEPL1 | huMAP3_02405.1 huMAP3_06013.1 huMAP3_11767.1 huMAP3_13049.1 |
MCOLN2 | huMAP3_01319.1 huMAP3_10268.1 huMAP3_11767.1 huMAP3_13049.1 |