hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13061.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNA3 | Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3) | 5 | UniProt NCBI |
| KCNAB1 | Voltage-gated potassium channel subunit beta-1 (EC 1.1.1.-) (K(+) channel subunit beta-1) (Kv-beta-1) | 5 | UniProt NCBI |
| KCNAB2 | Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2) (hKvbeta2) | 5 | UniProt NCBI |
| KCNAB3 | Voltage-gated potassium channel subunit beta-3 (EC 1.1.1.-) (K(+) channel subunit beta-3) (Kv-beta-3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296072 | 1.4356709255e-09 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | Voltage gated Potassium channels |
| REAC:R-HSA-1296071 | 6.92118227041e-08 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | Potassium Channels |
| GO:0008076 | 8.32139586928e-06 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | voltage-gated potassium channel complex |
| GO:0034705 | 1.37313780553e-05 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | potassium channel complex |
| REAC:R-HSA-112316 | 3.09235191422e-05 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | Neuronal System |
| WP:WP702 | 0.000139209137611 | 0.75 | KCNAB1 KCNAB2 KCNAB3 | Metapathway biotransformation Phase I and II |
| GO:0071805 | 0.000238882641259 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | potassium ion transmembrane transport |
| GO:0034703 | 0.000298882018117 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | cation channel complex |
| GO:0006813 | 0.000317929863268 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | potassium ion transport |
| GO:0004033 | 0.000777349058504 | 0.75 | KCNAB1 KCNAB2 KCNAB3 | aldo-keto reductase (NADP) activity |
| GO:0034702 | 0.000822442198332 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | monoatomic ion channel complex |
| GO:0015459 | 0.00209449363787 | 0.75 | KCNAB1 KCNAB2 KCNAB3 | potassium channel regulator activity |
| GO:1902495 | 0.00379124230895 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | transmembrane transporter complex |
| GO:1990351 | 0.0052054047953 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | transporter complex |
| GO:1901379 | 0.0089837173405 | 0.75 | KCNAB1 KCNAB2 KCNAB3 | regulation of potassium ion transmembrane transport |
| GO:0043266 | 0.0118300289699 | 0.75 | KCNAB1 KCNAB2 KCNAB3 | regulation of potassium ion transport |
| CORUM:7389 | 0.0249718442456 | 0.25 | KCNAB2 | Potassium channel complex (KCNA1, KCNA2, KCNAB2) |
| GO:0098797 | 0.0296421612139 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | plasma membrane protein complex |
| GO:0098662 | 0.0299356479586 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | inorganic cation transmembrane transport |
| GO:0098655 | 0.0311314419202 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | monoatomic cation transmembrane transport |
| GO:0098660 | 0.0416553027564 | 1.0 | KCNAB1 KCNA3 KCNAB3 KCNAB2 | inorganic ion transmembrane transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| KCNAB2 | KCNAB3 | 0.998 | 0.132 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| KCNAB1 | KCNAB2 | 0.988 | 0.63 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| KCNAB2 | KCNA3 | 0.944 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes