hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13104.1
Complex Portal: CPX-14533
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| COL2A1 | Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin] | 5 | UniProt NCBI |
| OSCAR | Osteoclast-associated immunoglobulin-like receptor (Osteoclast-associated receptor) (hOSCAR) (Polymeric immunoglobulin receptor 3) (PIgR-3) (PIgR3) (Poly-Ig receptor 3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-198933 | 0.00795599471791 | 1.0 | COL2A1 OSCAR | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| HPA:0200271 | 0.0351752340474 | 0.5 | COL2A1 | eye; hyaloid membrane[>=Low] |
| HPA:0200272 | 0.0351752340474 | 0.5 | COL2A1 | eye; hyaloid membrane[>=Medium] |
| HP:0031520 | 0.0499436884913 | 0.5 | COL2A1 | Groin pain |
| HP:0031153 | 0.0499436884913 | 0.5 | COL2A1 | Membranous vitreous appearance |
| HP:0011860 | 0.0499436884913 | 0.5 | COL2A1 | Metaphyseal dappling |
| HP:0009290 | 0.0499436884913 | 0.5 | COL2A1 | Short distal phalanx of the 4th finger |
| HP:0009289 | 0.0499436884913 | 0.5 | COL2A1 | Aplasia/Hypoplasia of the distal phalanx of the 4th finger |
| HP:0009282 | 0.0499436884913 | 0.5 | COL2A1 | Abnormality of the distal phalanx of the 4th finger |
| HP:0008452 | 0.0499436884913 | 0.5 | COL2A1 | Wafer-thin platyspondyly |
| HP:0008271 | 0.0499436884913 | 0.5 | COL2A1 | Abnormal cartilage collagen |
| HP:0008142 | 0.0499436884913 | 0.5 | COL2A1 | Delayed calcaneal ossification |
| HP:0006172 | 0.0499436884913 | 0.5 | COL2A1 | Flattened, squared-off epiphyses of tubular bones |
| HP:0006019 | 0.0499436884913 | 0.5 | COL2A1 | Reduced proximal interphalangeal joint space |
| HP:0005451 | 0.0499436884913 | 0.5 | COL2A1 | Decreased cranial base ossification |
| HP:0005193 | 0.0499436884913 | 0.5 | COL2A1 | Restricted large joint movement |
| HP:0005068 | 0.0499436884913 | 0.5 | COL2A1 | Absent styloid process of ulna |
| HP:0004605 | 0.0499436884913 | 0.5 | COL2A1 | Absent vertebral body mineralization |
| HP:0004591 | 0.0499436884913 | 0.5 | COL2A1 | Disc-like vertebral bodies |
| HP:0004557 | 0.0499436884913 | 0.5 | COL2A1 | Anterior vertebral fusion |
| HP:0004180 | 0.0499436884913 | 0.5 | COL2A1 | Short distal phalanx of the 3rd finger |
| HP:0004035 | 0.0499436884913 | 0.5 | COL2A1 | Abnormal ulnar styloid process morphology |
| HP:0003888 | 0.0499436884913 | 0.5 | COL2A1 | Flattened humeral heads |
| HP:0100734 | 0.0499436884913 | 0.5 | COL2A1 | Abnormal vertebral epiphysis morphology |
| HP:0200003 | 0.0499436884913 | 0.5 | COL2A1 | Splayed epiphyses |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| COL2A1 | OSCAR | 0.855 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| COL2A1 | huMAP3_09608.1 huMAP3_10984.1 huMAP3_12884.1 huMAP3_13038.1 huMAP3_13104.1 |
| OSCAR | huMAP3_12884.1 huMAP3_13038.1 huMAP3_13104.1 |