hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13117.1
Complex Portal: CPX-23283
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCDHGA7 | Protocadherin gamma-A7 (PCDH-gamma-A7) | 4 | UniProt NCBI |
| PCDHA11 | Protocadherin alpha-11 (PCDH-alpha-11) | 4 | UniProt NCBI |
| NPAP1 | Nuclear pore-associated protein 1 | 5 | UniProt NCBI |
| PCDHGA10 | Protocadherin gamma-A10 (PCDH-gamma-A10) | 4 | UniProt NCBI |
| LTBP1 | Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1) | 5 | UniProt NCBI |
| PCDHGA3 | Protocadherin gamma-A3 (PCDH-gamma-A3) | 4 | UniProt NCBI |
| PCDHA9 | Protocadherin alpha-9 (PCDH-alpha-9) | 5 | UniProt NCBI |
| PCDHGA12 | Protocadherin gamma-A12 (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin-3) | 4 | UniProt NCBI |
| PCDHGA9 | Protocadherin gamma-A9 (PCDH-gamma-A9) | 4 | UniProt NCBI |
| PCDHGA4 | Protocadherin gamma-A4 (PCDH-gamma-A4) | 4 | UniProt NCBI |
| PCDHGA8 | Protocadherin gamma-A8 (PCDH-gamma-A8) | 4 | UniProt NCBI |
| PCDHB14 | Protocadherin beta-14 (PCDH-beta-14) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0007155 | 2.65280759727e-06 | 0.833333333333 | PCDHGA3 PCDHGA10 PCDHA9 PCDHGA7 PCDHA11 PCDHGA4 PCDHGA9 PCDHB14 PCDHGA12 PCDHGA8 | cell adhesion |
| TF:M11470 | 0.00354579646819 | 0.583333333333 | PCDHGA10 PCDHGA9 PCDHGA8 PCDHGA4 NPAP1 PCDHB14 PCDHGA12 | Factor: PDEF; motif: NAMCCGGATGYN |
| TF:M11571 | 0.00564313932845 | 0.916666666667 | PCDHGA3 PCDHGA10 PCDHA9 PCDHGA12 PCDHA11 PCDHGA9 NPAP1 PCDHB14 PCDHGA7 PCDHGA8 LTBP1 | Factor: HNF-3alpha; motif: YTRWGTMAATATTTRCWYWN |
| TF:M02075 | 0.00734674950463 | 0.833333333333 | PCDHGA3 PCDHGA10 PCDHGA7 PCDHA11 PCDHGA9 NPAP1 PCDHB14 PCDHGA4 PCDHGA12 PCDHGA8 | Factor: PDEF; motif: MCCGGATNTN |
| TF:M10116 | 0.0384931256351 | 0.666666666667 | PCDHGA3 PCDHGA10 PCDHA9 PCDHGA7 PCDHA11 PCDHGA8 PCDHGA9 PCDHGA12 | Factor: ZID; motif: GGNGMTGGAGCCN |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PCDHGA10 | PCDHGA4 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHGA9 | PCDHGA3 | 0.999 |
mutually_exclusive (Q9Y5G9)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHA11 | PCDHB14 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PCDHA9 | PCDHGA4 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PCDHGA9 | PCDHGA12 | 0.993 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA9 | PCDHB14 | 0.992 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHA9 | PCDHGA9 | 0.991 |
mutually_exclusive (O60330)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHA9 | PCDHGA12 | 0.991 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHGA3 | PCDHGA4 | 0.991 |
mutually_exclusive (Q9Y5G4)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PCDHGA7 | PCDHGA10 | 0.99 |
mutually_exclusive (Q9Y5G9)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHGA12 | PCDHGA4 | 0.988 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PCDHGA8 | PCDHGA4 | 0.988 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PCDHA11 | PCDHA9 | 0.985 |
mutually_exclusive (Q9Y5H3)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHGA7 | PCDHGA4 | 0.982 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PCDHA11 | PCDHGA10 | 0.981 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHGA8 | PCDHGA9 | 0.98 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| NPAP1 | PCDHGA12 | 0.98 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| PCDHA9 | PCDHGA10 | 0.962 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHGA7 | PCDHGA12 | 0.958 |
mutually_exclusive (Q9Y5G9)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHGA9 | PCDHGA4 | 0.944 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PCDHGA7 | LTBP1 | 0.917 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHB14 | PCDHGA4 | 0.902 | bioplex3_WMM WMM_only | ||
| PCDHB14 | PCDHGA12 | 0.869 |
mutually_exclusive (Q9Y5H5)
|
bioplex3_WMM WMM_only | |
| LTBP1 | PCDHGA9 | 0.849 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHGA9 | PCDHGA10 | 0.784 |
mutually_exclusive (Q9Y5G9)
|
bioplex3_WMM WMM_only | |
| PCDHGA12 | PCDHGA10 | 0.773 | bioplex3_WMM WMM_only | ||
| PCDHB14 | PCDHGA9 | 0.696 | bioplex3_WMM WMM_only | ||
| PCDHB14 | PCDHGA10 | 0.634 |
mutually_exclusive (Q9Y5H5)
|
bioplex3_WMM WMM_only | |
| LTBP1 | PCDHGA12 | 0.419 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHGA7 | PCDHGA9 | 0.348 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHGA7 | PCDHGA8 | 0.265 | bioplex_WMM bioplex3_WMM WMM_only | ||
| LTBP1 | PCDHGA8 | 0.237 | bioplex_WMM bioplex3_WMM WMM_only | ||
| LTBP1 | PCDHGA10 | 0.163 | bioplex3_WMM WMM_only | ||
| PCDHA11 | LTBP1 | 0.144 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHGA8 | PCDHGA3 | 0.135 | bioplex3_WMM WMM_only | ||
| PCDHGA7 | PCDHGA3 | 0.113 |
mutually_exclusive (Q9Y5G9)
|
bioplex3_WMM WMM_only | |
| LTBP1 | PCDHGA3 | 0.087 | bioplex3_WMM WMM_only | ||
| PCDHGA8 | PCDHGA12 | 0.079 | bioplex3_WMM WMM_only | ||
| PCDHGA3 | PCDHGA12 | 0.079 | bioplex3_WMM WMM_only | ||
| PCDHGA8 | PCDHGA10 | 0.078 |
mutually_exclusive (Q9Y5G9)
|
bioplex3_WMM WMM_only | |
| PCDHGA3 | PCDHGA10 | 0.078 |
mutually_exclusive (Q9Y5G9)
|
bioplex3_WMM WMM_only | |
| PCDHA9 | LTBP1 | 0.072 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes