hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13124.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FHIT | Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Adenosine 5'-monophosphoramidase FHIT) (EC 3.9.1.-) (Adenylylsulfatase) (EC 3.6.2.1) (Adenylylsulfate-ammonia adenylyltransferase) (EC 2.7.7.51) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (Fragile histidine triad protein) | 5 | UniProt NCBI |
| PIWIL1 | Piwi-like protein 1 (EC 3.1.26.-) | 5 | UniProt NCBI |
| PIWIL4 | Piwi-like protein 4 | 5 | UniProt NCBI |
| TDRKH | Tudor and KH domain-containing protein (Tudor domain-containing protein 2) | 5 | UniProt NCBI |
| ARHGAP19 | Rho GTPase-activating protein 19 (Rho-type GTPase-activating protein 19) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5601884 | 5.51556094215e-06 | 0.6 | PIWIL1 TDRKH PIWIL4 | PIWI-interacting RNA (piRNA) biogenesis |
| GO:0034587 | 0.000349481973524 | 0.6 | PIWIL1 TDRKH PIWIL4 | piRNA processing |
| GO:0043186 | 0.000652677252708 | 0.6 | PIWIL1 TDRKH PIWIL4 | P granule |
| GO:0045495 | 0.000652677252708 | 0.6 | PIWIL1 TDRKH PIWIL4 | pole plasm |
| GO:0060293 | 0.000652677252708 | 0.6 | PIWIL1 TDRKH PIWIL4 | germ plasm |
| REAC:R-HSA-211000 | 0.000823183245594 | 0.6 | PIWIL1 TDRKH PIWIL4 | Gene Silencing by RNA |
| GO:0034584 | 0.00468200720083 | 0.4 | PIWIL1 PIWIL4 | piRNA binding |
| GO:0070918 | 0.0250826699056 | 0.6 | PIWIL1 TDRKH PIWIL4 | regulatory ncRNA processing |
| WP:WP4673 | 0.0399620586052 | 0.4 | PIWIL1 PIWIL4 | Male infertility |
| GO:0071547 | 0.0468008499735 | 0.4 | PIWIL4 TDRKH | piP-body |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PIWIL4 | TDRKH | 0.908 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ARHGAP19 | TDRKH | 0.834 | 0.138 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PIWIL1 | TDRKH | 0.822 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ARHGAP19 | FHIT | 0.801 | 0.086 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| FHIT | TDRKH | 0.16 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes