hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13140.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TBC1D7 | TBC1 domain family member 7 (Cell migration-inducing protein 23) | 5 | UniProt NCBI |
| KIF27 | Kinesin-like protein KIF27 | 5 | UniProt NCBI |
| TSC1 | Hamartin (Tuberous sclerosis 1 protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6889 | 1.02521027753e-05 | 0.666666666667 | TSC1 TBC1D7 | TSC complex |
| GO:0033596 | 0.00421361424067 | 0.666666666667 | TSC1 TBC1D7 | TSC1-TSC2 complex |
| REAC:R-HSA-8854214 | 0.00504394814871 | 0.666666666667 | TSC1 TBC1D7 | TBC/RABGAPs |
| WP:WP4549 | 0.0067573392711 | 0.666666666667 | TSC1 TBC1D7 | Fragile X syndrome |
| KEGG:04150 | 0.00824863650471 | 0.666666666667 | TSC1 TBC1D7 | mTOR signaling pathway |
| HP:0001355 | 0.00841415615575 | 0.666666666667 | TSC1 TBC1D7 | Megalencephaly |
| REAC:R-HSA-199991 | 0.0145539954891 | 1.0 | KIF27 TBC1D7 TSC1 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.017135828319 | 1.0 | KIF27 TBC1D7 TSC1 | Vesicle-mediated transport |
| REAC:R-HSA-9007101 | 0.0392065258044 | 0.666666666667 | TSC1 TBC1D7 | Rab regulation of trafficking |
| CORUM:75 | 0.0499402709677 | 0.333333333333 | TSC1 | TSC1-TSC2 complex |
| CORUM:7157 | 0.0499402709677 | 0.333333333333 | TSC1 | TSC1-TSC2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TSC1 | TBC1D7 | 1.0 | 0.19 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| TBC1D7 | KIF27 | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TSC1 | KIF27 | 0.378 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| TBC1D7 | huMAP3_04821.1 huMAP3_13140.1 |
| KIF27 | huMAP3_04821.1 huMAP3_13140.1 |
| TSC1 | huMAP3_04821.1 huMAP3_13140.1 |