hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13140.1
Complex Portal: CPX-14364
Confidence: Medium  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TBC1D7 | TBC1 domain family member 7 (Cell migration-inducing protein 23) | 5 | UniProt   NCBI |
| KIF27 | Kinesin-like protein KIF27 | 5 | UniProt   NCBI |
| TSC1 | Hamartin (Tuberous sclerosis 1 protein) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   CORUM:6889 | 1.02521027753e-05 | 0.666666666667 | TSC1 TBC1D7 | TSC complex |
|   GO:0033596 | 0.00421361424067 | 0.666666666667 | TSC1 TBC1D7 | TSC1-TSC2 complex |
|   REAC:R-HSA-8854214 | 0.00504394814871 | 0.666666666667 | TSC1 TBC1D7 | TBC/RABGAPs |
|   WP:WP4549 | 0.0067573392711 | 0.666666666667 | TSC1 TBC1D7 | Fragile X syndrome |
|   KEGG:04150 | 0.00824863650471 | 0.666666666667 | TSC1 TBC1D7 | mTOR signaling pathway |
|   HP:0001355 | 0.00841415615575 | 0.666666666667 | TSC1 TBC1D7 | Megalencephaly |
|   REAC:R-HSA-199991 | 0.0145539954891 | 1.0 | TSC1 TBC1D7 KIF27 | Membrane Trafficking |
|   REAC:R-HSA-5653656 | 0.017135828319 | 1.0 | TSC1 TBC1D7 KIF27 | Vesicle-mediated transport |
|   REAC:R-HSA-9007101 | 0.0392065258044 | 0.666666666667 | TSC1 TBC1D7 | Rab regulation of trafficking |
|   CORUM:75 | 0.0499402709677 | 0.333333333333 | TSC1 | TSC1-TSC2 complex |
|   CORUM:7157 | 0.0499402709677 | 0.333333333333 | TSC1 | TSC1-TSC2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  TSC1 |  TBC1D7 | 1.0 | 0.19           |          | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     hein ()     bioplex3_HCT116     |
|  TBC1D7 |  KIF27 | 0.991 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  TSC1 |  KIF27 | 0.378 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| TBC1D7 | huMAP3_04821.1 huMAP3_13140.1 |
| KIF27 | huMAP3_04821.1 huMAP3_13140.1 |
| TSC1 | huMAP3_04821.1 huMAP3_13140.1 |