hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13151.1
Complex Portal: CPX-16948
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FRG1 | Protein FRG1 (FSHD region gene 1 protein) | 5 | UniProt NCBI |
| UBE2O | (E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O) | 5 | UniProt NCBI |
| AKT2 | RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP1559 | 0.0496447587094 | 0.333333333333 | AKT2 | Transcription factors regulate miRNAs related to cardiac hypertrophy |
| CORUM:3138 | 0.0499402709677 | 0.333333333333 | AKT2 | POSH-AKT2 complex |
| CORUM:3848 | 0.0499402709677 | 0.333333333333 | AKT2 | TCL1(trimer)-AKT2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| AKT2 | UBE2O | 0.979 | 0.146 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM | |
| FRG1 | UBE2O | 0.841 | 0.032 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM | |
| AKT2 | FRG1 | 0.002 | 0.036 | youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| FRG1 | huMAP3_05866.1 huMAP3_13151.1 |
| UBE2O | huMAP3_13151.1 |
| AKT2 | huMAP3_04364.1 huMAP3_10657.1 huMAP3_13151.1 |