hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_13164.1

Complex Portal: CPX-13401

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
ATXN2	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)	5	UniProt NCBI
ATXN2L	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein)	5	UniProt NCBI
CHD6	Chromodomain-helicase-DNA-binding protein 6 (CHD-6) (EC 3.6.4.12) (ATP-dependent helicase CHD6) (Radiation-induced gene B protein)	5	UniProt NCBI
DDX6	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)	5	UniProt NCBI
DMRTB1	Doublesex- and mab-3-related transcription factor B1	4	UniProt NCBI
GIGYF1	GRB10-interacting GYF protein 1 (PERQ amino acid-rich with GYF domain-containing protein 1)	5	UniProt NCBI
LSM12	Protein LSM12	5	UniProt NCBI
MCRIP2	MAPK regulated corepressor interacting protein 2 (Protein FAM195A)	4	UniProt NCBI
PUM1	Pumilio homolog 1 (HsPUM) (Pumilio-1)	5	UniProt NCBI
TRIM11	E3 ubiquitin-protein ligase TRIM11 (EC 2.3.2.27) (Protein BIA1) (RING finger protein 92) (Tripartite motif-containing protein 11)	5	UniProt NCBI

Showing 1 to 10 of 10 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0010494	4.39196371931e-05	0.5	MCRIP2 ATXN2L ATXN2 DDX6 PUM1	cytoplasmic stress granule
KEGG:05017	0.00353228654663	0.3	PUM1 ATXN2 ATXN2L	Spinocerebellar ataxia
GO:0036464	0.00646012184262	0.5	MCRIP2 ATXN2L ATXN2 DDX6 PUM1	cytoplasmic ribonucleoprotein granule
GO:0035770	0.0095744861373	0.5	MCRIP2 ATXN2L ATXN2 DDX6 PUM1	ribonucleoprotein granule
GO:0034063	0.0297425210859	0.3	DDX6 ATXN2 ATXN2L	stress granule assembly

Showing 1 to 5 of 5 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
LSM12	ATXN2L	1.0	0.514	structurally_consistent (dimer)	youn () bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM
MCRIP2	LSM12	1.0	0.146	structurally_consistent (dimer)	youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only
MCRIP2	ATXN2L	0.999	0.09	mutually_exclusive (Q3MHD2)	youn () bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only
LSM12	DDX6	0.999	0.114	structurally_consistent (dimer)	youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM
ATXN2L	DDX6	0.998	0.334	structurally_consistent (dimer)	youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM
MCRIP2	DDX6	0.998	0.122		youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only
ATXN2	MCRIP2	0.998	0.092	mutually_exclusive (Q3MHD2)	youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only
DMRTB1	TRIM11	0.997			bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116
PUM1	TRIM11	0.997	0.17		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ATXN2	PUM1	0.997	0.338		hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM treiber_WMM WMM_only

Showing 1 to 10 of 31 entries

Related Complexes

Genename	Complexes
GIGYF1	huMAP3_00770.1 huMAP3_02050.1 huMAP3_03545.1 huMAP3_07177.1 huMAP3_07906.1 huMAP3_08294.1 huMAP3_08375.1 huMAP3_09382.1 huMAP3_09383.1 huMAP3_10338.1 huMAP3_10440.1 huMAP3_12383.1 huMAP3_13164.1 huMAP3_13436.1 huMAP3_14201.1 huMAP3_14270.1
LSM12	huMAP3_00480.1 huMAP3_00574.1 huMAP3_02526.1 huMAP3_08431.1 huMAP3_08603.1 huMAP3_08724.1 huMAP3_10207.1 huMAP3_10338.1 huMAP3_11693.1 huMAP3_13164.1 huMAP3_13965.1 huMAP3_14201.1
ATXN2	huMAP3_00480.1 huMAP3_00574.1 huMAP3_02526.1 huMAP3_05847.1 huMAP3_06975.1 huMAP3_08431.1 huMAP3_08724.1 huMAP3_10207.1 huMAP3_10338.1 huMAP3_13164.1 huMAP3_14201.1
MCRIP2	huMAP3_00480.1 huMAP3_02526.1 huMAP3_08431.1 huMAP3_08724.1 huMAP3_08733.1 huMAP3_10207.1 huMAP3_10338.1 huMAP3_11693.1 huMAP3_13164.1 huMAP3_13965.1 huMAP3_14201.1
PUM1	huMAP3_00582.1 huMAP3_03682.1 huMAP3_05538.1 huMAP3_05758.1 huMAP3_06975.1 huMAP3_07115.1 huMAP3_07846.1 huMAP3_08338.1 huMAP3_09223.1 huMAP3_10625.1 huMAP3_10905.1 huMAP3_13164.1
TRIM11	huMAP3_05324.1 huMAP3_06284.1 huMAP3_08384.1 huMAP3_11536.1 huMAP3_13164.1 huMAP3_14201.1
DDX6	huMAP3_00770.1 huMAP3_02526.1 huMAP3_04773.1 huMAP3_07143.1 huMAP3_08431.1 huMAP3_08724.1 huMAP3_08733.1 huMAP3_09746.1 huMAP3_10207.1 huMAP3_10338.1 huMAP3_13161.1 huMAP3_13164.1 huMAP3_13965.1 huMAP3_14201.1
ATXN2L	huMAP3_00480.1 huMAP3_00574.1 huMAP3_02526.1 huMAP3_08431.1 huMAP3_08724.1 huMAP3_08733.1 huMAP3_10207.1 huMAP3_10338.1 huMAP3_11693.1 huMAP3_13164.1 huMAP3_13965.1 huMAP3_14201.1
DMRTB1	huMAP3_04248.1 huMAP3_05324.1 huMAP3_06284.1 huMAP3_08384.1 huMAP3_09547.1 huMAP3_11306.1 huMAP3_11536.1 huMAP3_12062.1 huMAP3_13164.1 huMAP3_13170.1 huMAP3_14022.1 huMAP3_14201.1
CHD6	huMAP3_01016.1 huMAP3_05373.1 huMAP3_10107.1 huMAP3_10798.1 huMAP3_13164.1