hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13169.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PRRT4 | Proline-rich transmembrane protein 4 | 3 | UniProt NCBI |
| PITPNM1 | Membrane-associated phosphatidylinositol transfer protein 1 (Drosophila retinal degeneration B homolog) (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) | 5 | UniProt NCBI |
| RASSF1 | Ras association domain-containing protein 1 | 5 | UniProt NCBI |
| PITPNM2 | Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) | 5 | UniProt NCBI |
| OSBP2 | Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4) | 5 | UniProt NCBI |
| OSBPL9 | Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9) | 5 | UniProt NCBI |
| SLC22A15 | Solute carrier family 22 member 15 (Fly-like putative transporter 1) (Flipt 1) | 5 | UniProt NCBI |
| OSBPL10 | Oxysterol-binding protein-related protein 10 (ORP-10) (OSBP-related protein 10) | 5 | UniProt NCBI |
| PITPNM3 | Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (PITPnm 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1) | 5 | UniProt NCBI |
| OSBPL2 | Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2) | 5 | UniProt NCBI |
| RASSF3 | Ras association domain-containing protein 3 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005319 | 2.49622632864e-08 | 0.636363636364 | OSBPL10 PITPNM1 OSBPL9 OSBPL2 OSBP2 PITPNM3 PITPNM2 | lipid transporter activity |
| GO:0008526 | 6.06890408176e-07 | 0.363636363636 | PITPNM1 OSBPL2 PITPNM2 PITPNM3 | phosphatidylinositol transfer activity |
| REAC:R-HSA-1483226 | 8.21076918201e-07 | 0.272727272727 | PITPNM1 PITPNM2 PITPNM3 | Synthesis of PI |
| GO:0005548 | 3.49422884807e-06 | 0.454545454545 | PITPNM3 PITPNM1 OSBPL2 PITPNM2 OSBPL10 | phospholipid transporter activity |
| GO:0120014 | 4.18126230382e-05 | 0.363636363636 | PITPNM1 OSBPL2 PITPNM2 PITPNM3 | phospholipid transfer activity |
| GO:0015248 | 0.000128722703999 | 0.363636363636 | OSBPL2 OSBPL10 OSBP2 OSBPL9 | sterol transporter activity |
| REAC:R-HSA-1483206 | 0.00020688078241 | 0.363636363636 | PITPNM3 PITPNM1 PITPNM2 OSBPL10 | Glycerophospholipid biosynthesis |
| GO:0005215 | 0.00043184335836 | 0.727272727273 | OSBPL10 PITPNM1 OSBPL9 OSBPL2 OSBP2 PITPNM3 SLC22A15 PITPNM2 | transporter activity |
| REAC:R-HSA-556833 | 0.000526066143925 | 0.545454545455 | OSBPL10 PITPNM1 OSBPL2 OSBPL9 PITPNM3 PITPNM2 | Metabolism of lipids |
| GO:0120013 | 0.000704674168151 | 0.363636363636 | PITPNM1 OSBPL2 PITPNM2 PITPNM3 | lipid transfer activity |
| GO:0032934 | 0.00152343109181 | 0.363636363636 | OSBPL2 OSBPL10 OSBP2 OSBPL9 | sterol binding |
| REAC:R-HSA-1483257 | 0.00162674562086 | 0.363636363636 | PITPNM3 PITPNM1 PITPNM2 OSBPL10 | Phospholipid metabolism |
| GO:0005496 | 0.0053914775929 | 0.363636363636 | OSBPL2 OSBPL10 OSBP2 OSBPL9 | steroid binding |
| REAC:R-HSA-192105 | 0.0278014860056 | 0.181818181818 | OSBPL9 OSBPL2 | Synthesis of bile acids and bile salts |
| GO:0008289 | 0.0361183348412 | 0.545454545455 | OSBPL10 PITPNM1 OSBPL2 OSBPL9 OSBP2 PITPNM2 | lipid binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| PRRT4 | RASSF1 | 0.904 | |
| SLC22A15 | RASSF3 | 0.904 | |
| SLC22A15 | OSBPL2 | 0.904 | |
| SLC22A15 | PRRT4 | 0.902 | |
| PRRT4 | PITPNM2 | 0.902 | |
| SLC22A15 | PITPNM2 | 0.902 | |
| PITPNM1 | PRRT4 | 0.902 | |
| PRRT4 | RASSF3 | 0.902 | |
| SLC22A15 | PITPNM1 | 0.902 | |
| PITPNM1 | RASSF3 | 0.902 | 0.088 |
| PRRT4 | OSBPL2 | 0.902 | |
| PITPNM2 | RASSF3 | 0.902 | 0.072 |
| OSBP2 | PRRT4 | 0.902 | |
| PITPNM3 | PRRT4 | 0.902 | |
| PITPNM1 | OSBP2 | 0.897 | 0.108 |
| OSBP2 | PITPNM2 | 0.897 | 0.082 |
| SLC22A15 | RASSF1 | 0.892 | |
| PRRT4 | OSBPL9 | 0.892 | |
| PITPNM1 | PITPNM2 | 0.881 | 0.086 |
| PITPNM2 | OSBPL10 | 0.88 | 0.036 |
| PITPNM1 | OSBPL10 | 0.88 | 0.064 |
| OSBPL2 | RASSF3 | 0.869 | 0.056 |
| OSBP2 | OSBPL9 | 0.862 | 0.138 |
| OSBP2 | OSBPL10 | 0.849 | 0.09 |
| PITPNM1 | PITPNM3 | 0.843 | |
| PITPNM3 | PITPNM2 | 0.843 | |
| PITPNM1 | RASSF1 | 0.828 | 0.068 |
| RASSF3 | RASSF1 | 0.81 | 0.09 |
| PITPNM2 | OSBPL2 | 0.797 | 0.086 |
| PITPNM1 | OSBPL2 | 0.797 | 0.088 |
| PITPNM3 | RASSF1 | 0.793 | |
| PITPNM3 | OSBPL2 | 0.793 | |
| PITPNM2 | RASSF1 | 0.781 | 0.06 |
| PITPNM3 | OSBP2 | 0.778 | |
| PITPNM1 | OSBPL9 | 0.772 | 0.056 |
| PITPNM2 | OSBPL9 | 0.772 | 0.062 |
| OSBPL2 | RASSF1 | 0.739 | 0.082 |
| PITPNM3 | RASSF3 | 0.722 | |
| SLC22A15 | OSBP2 | 0.722 | |
| SLC22A15 | PITPNM3 | 0.717 | |
| OSBPL9 | RASSF3 | 0.715 | 0.044 |
| OSBPL9 | RASSF1 | 0.704 | 0.164 |
| SLC22A15 | OSBPL9 | 0.697 | |
| OSBPL9 | OSBPL2 | 0.681 | 0.056 |
| PRRT4 | OSBPL10 | 0.676 | |
| OSBP2 | RASSF3 | 0.647 | 0.066 |
| OSBPL2 | OSBPL10 | 0.641 | 0.02 |
| SLC22A15 | OSBPL10 | 0.633 | |
| OSBPL9 | OSBPL10 | 0.624 | 0.804 |
| OSBPL10 | RASSF1 | 0.623 | 0.08 |
| PITPNM3 | OSBPL10 | 0.617 | |
| PITPNM3 | OSBPL9 | 0.611 | |
| OSBP2 | OSBPL2 | 0.594 | 0.1 |
| OSBP2 | RASSF1 | 0.594 | 0.09 |
| RASSF3 | OSBPL10 | 0.401 | 0.032 |
Related Complexes