hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13171.1
Complex Portal: CPX-20262
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SIM2 | Single-minded homolog 2 (Class E basic helix-loop-helix protein 15) (bHLHe15) | 5 | UniProt NCBI |
| NPAS3 | Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Class E basic helix-loop-helix protein 12) (bHLHe12) (Member of PAS protein 6) (PAS domain-containing protein 6) | 5 | UniProt NCBI |
| ABCC12 | ATP-binding cassette sub-family C member 12 (Multidrug resistance-associated protein 9) | 5 | UniProt NCBI |
| SIM1 | Single-minded homolog 1 (Class E basic helix-loop-helix protein 14) (bHLHe14) | 4 | UniProt NCBI |
| ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1) | 5 | UniProt NCBI |
| ARNT | Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ARNT2 | SIM2 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SIM1 | ARNT2 | 0.994 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SIM2 | ARNT | 0.993 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NPAS3 | ARNT2 | 0.987 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NPAS3 | ABCC12 | 0.977 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NPAS3 | ARNT | 0.954 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ARNT2 | ARNT | 0.827 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SIM1 | SIM2 | 0.572 |
mutually_exclusive (Q9HBZ2)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| ABCC12 | ARNT2 | 0.274 | bioplex3_WMM WMM_only | ||
| ABCC12 | ARNT | 0.076 | bioplex3_WMM WMM_only |
Related Complexes