hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13174.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SAP30BP | SAP30-binding protein (Transcriptional regulator protein HCNGP) | 5 | UniProt NCBI |
| MCM8 | DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8) | 5 | UniProt NCBI |
| MCM9 | DNA helicase MCM9 (hMCM9) (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9) | 5 | UniProt NCBI |
| HORMAD2 | HORMA domain-containing protein 2 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0032406 | 0.0028092043205 | 0.5 | MCM8 MCM9 | MutLbeta complex binding |
| GO:0032408 | 0.0028092043205 | 0.5 | MCM8 MCM9 | MutSbeta complex binding |
| GO:0097362 | 0.0028092043205 | 0.5 | MCM8 MCM9 | MCM8-MCM9 complex |
| GO:0036298 | 0.0028092043205 | 0.5 | MCM8 MCM9 | recombinational interstrand cross-link repair |
| GO:0070716 | 0.0028092043205 | 0.5 | MCM8 MCM9 | mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication |
| HP:0008232 | 0.0135443934278 | 0.5 | MCM8 MCM9 | Elevated circulating follicle stimulating hormone level |
| WP:WP5316 | 0.0208408229239 | 0.5 | MCM8 MCM9 | Primary ovarian insufficiency |
| HP:0030346 | 0.0476300363671 | 0.5 | MCM8 MCM9 | Abnormal circulating follicle-stimulating hormone concentration |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MCM9 | MCM8 | 0.999 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SAP30BP | HORMAD2 | 0.947 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MCM9 | HORMAD2 | 0.934 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MCM8 | HORMAD2 | 0.387 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SAP30BP | MCM9 | 0.045 | 0.052 | bioplex3_WMM WMM_only |
| SAP30BP | MCM8 | 0.039 | 0.072 | bioplex3_WMM WMM_only |
Related Complexes