hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13189.1
Complex Portal: CPX-12742
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CGAS | Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1) | 5 | UniProt NCBI |
| PHF8 | Histone lysine demethylase PHF8 (EC 1.14.11.27) (EC 1.14.11.65) (PHD finger protein 8) ([histone H3]-dimethyl-L-lysine(36) demethylase PHF8) ([histone H3]-dimethyl-L-lysine(9) demethylase PHF8) | 5 | UniProt NCBI |
| H2BC21 | Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q) | 5 | UniProt NCBI |
| RNF138 | E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RNF138 | PHF8 | 0.899 | 0.082 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PHF8 | CGAS | 0.849 | 0.056 | hein_WMM hein () | |
| PHF8 | H2BC21 | 0.816 | hein_WMM hein () | ||
| CGAS | H2BC21 | 0.232 | hein_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| CGAS | huMAP3_13189.1 |
| PHF8 | huMAP3_07764.1 huMAP3_08174.1 huMAP3_13189.1 |
| H2BC21 | huMAP3_13189.1 |
| RNF138 | huMAP3_02770.1 huMAP3_03887.1 huMAP3_04296.1 huMAP3_04948.1 huMAP3_05402.1 huMAP3_08665.1 huMAP3_11707.1 huMAP3_13189.1 huMAP3_13930.1 huMAP3_14418.1 huMAP3_14756.1 |