hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13196.1
Complex Portal: CPX-19086
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GREB1 | Protein GREB1 (Gene regulated in breast cancer 1 protein) | 5 | UniProt NCBI |
| DENND6B | Protein DENND6B (DENN domain-containing protein 6B) | 3 | UniProt NCBI |
| RPS6KC1 | Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein) | 5 | UniProt NCBI |
| DENND6A | Protein DENND6A (DENN domain-containing protein 6A) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8876198 | 0.0329793636325 | 0.5 | DENND6B DENND6A | RAB GEFs exchange GTP for GDP on RABs |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RPS6KC1 | DENND6A | 0.995 | 0.108 | hein_WMM bioplex3_HEK293 bioplex3_WMM hein () | |
| DENND6B | DENND6A | 0.958 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| DENND6A | GREB1 | 0.811 | bioplex3_WMM WMM_only | ||
| DENND6B | RPS6KC1 | 0.415 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| GREB1 | huMAP3_11680.1 huMAP3_11838.1 huMAP3_13196.1 huMAP3_13321.1 huMAP3_13545.1 huMAP3_13887.1 |
| DENND6B | huMAP3_00548.1 huMAP3_13196.1 huMAP3_13618.1 |
| RPS6KC1 | huMAP3_00548.1 huMAP3_06655.1 huMAP3_13196.1 huMAP3_13618.1 |
| DENND6A | huMAP3_00548.1 huMAP3_06655.1 huMAP3_07321.1 huMAP3_13196.1 huMAP3_13618.1 |