hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_13211.1

Complex Portal: CPX-21674

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
BVES	Blood vessel epicardial substance (hBVES) (Popeye domain-containing protein 1) (Popeye protein 1)	5	UniProt NCBI
CYP26A1	Cytochrome P450 26A1 (CYP26A1) (EC 1.14.13.-) (Cytochrome P450 retinoic acid-inactivating 1) (Cytochrome P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase) (Retinoic acid-metabolizing cytochrome)	5	UniProt NCBI
KCNF1	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1)	5	UniProt NCBI
KCNB2	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2)	5	UniProt NCBI
KCNQ5	Potassium voltage-gated channel subfamily KQT member 5 (KQT-like 5) (Potassium channel subunit alpha KvLQT5) (Voltage-gated potassium channel subunit Kv7.5)	5	UniProt NCBI
KCNS3	Potassium voltage-gated channel subfamily S member 3 (Delayed-rectifier K(+) channel alpha subunit 3) (Voltage-gated potassium channel subunit Kv9.3)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-1296072	2.16411786968e-08	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	Voltage gated Potassium channels
REAC:R-HSA-1296071	1.03872291526e-06	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	Potassium Channels
GO:0005249	9.04396960067e-05	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	voltage-gated potassium channel activity
GO:0008076	0.000124138457674	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	voltage-gated potassium channel complex
GO:0034705	0.000204687081424	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	potassium channel complex
GO:0005267	0.000204687081424	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	potassium channel activity
REAC:R-HSA-112316	0.000452345664425	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	Neuronal System
GO:0022843	0.000684451996602	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	voltage-gated monoatomic cation channel activity
GO:0015079	0.000792088897246	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	potassium ion transmembrane transporter activity
GO:0022832	0.00147034444981	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	voltage-gated channel activity
GO:0005244	0.00147034444981	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	voltage-gated monoatomic ion channel activity
GO:0071805	0.00353670256676	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	potassium ion transmembrane transport
GO:0034703	0.00442159197262	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	cation channel complex
GO:0006813	0.00470234449591	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	potassium ion transport
GO:0034702	0.0121174468054	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	monoatomic ion channel complex
GO:0022836	0.0156557881857	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	gated channel activity
GO:0005261	0.0249855480901	0.666666666667	KCNS3 KCNF1 KCNB2 KCNQ5	monoatomic cation channel activity

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
KCNS3	KCNB2	0.997			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
CYP26A1	KCNS3	0.995			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
KCNS3	BVES	0.995			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
KCNB2	KCNF1	0.986			bioplex3_HEK293 bioplex3_WMM WMM_only
KCNS3	KCNQ5	0.984			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
CYP26A1	BVES	0.333			bioplex_WMM bioplex3_WMM WMM_only
CYP26A1	KCNB2	0.333			bioplex_WMM bioplex3_WMM WMM_only
KCNB2	BVES	0.303			bioplex_WMM bioplex3_WMM WMM_only
CYP26A1	KCNQ5	0.265			bioplex_WMM bioplex3_WMM WMM_only
KCNB2	KCNQ5	0.201			bioplex_WMM bioplex3_WMM youn_WMM WMM_only
KCNQ5	BVES	0.164			bioplex_WMM bioplex3_WMM WMM_only

Related Complexes

Genename	Complexes
BVES	huMAP3_05419.1 huMAP3_06425.1 huMAP3_08369.1 huMAP3_09386.1 huMAP3_13211.1 huMAP3_13896.1 huMAP3_14088.1 huMAP3_15052.1 huMAP3_15182.1
CYP26A1	huMAP3_00195.1 huMAP3_00449.1 huMAP3_02626.1 huMAP3_07369.1 huMAP3_08102.1 huMAP3_08250.1 huMAP3_08369.1 huMAP3_09190.1 huMAP3_09386.1 huMAP3_10549.1 huMAP3_11085.1 huMAP3_13211.1 huMAP3_13896.1
KCNF1	huMAP3_01373.1 huMAP3_04012.1 huMAP3_12378.1 huMAP3_13211.1 huMAP3_13990.1 huMAP3_15210.1
KCNB2	huMAP3_00449.1 huMAP3_01373.1 huMAP3_04012.1 huMAP3_12378.1 huMAP3_13211.1 huMAP3_13990.1 huMAP3_14570.1 huMAP3_15210.1
KCNQ5	huMAP3_01704.1 huMAP3_02626.1 huMAP3_07369.1 huMAP3_07726.1 huMAP3_08102.1 huMAP3_08250.1 huMAP3_08369.1 huMAP3_09190.1 huMAP3_09386.1 huMAP3_10268.1 huMAP3_10549.1 huMAP3_11767.1 huMAP3_12212.1 huMAP3_12566.1 huMAP3_13211.1 huMAP3_13896.1 huMAP3_13961.1 huMAP3_15289.1
KCNS3	huMAP3_00195.1 huMAP3_00449.1 huMAP3_02626.1 huMAP3_07369.1 huMAP3_08102.1 huMAP3_08250.1 huMAP3_08369.1 huMAP3_09190.1 huMAP3_09386.1 huMAP3_10549.1 huMAP3_11085.1 huMAP3_13211.1 huMAP3_13896.1 huMAP3_14570.1