hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13216.1
Complex Portal: CPX-24770
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TOM1 | Target of Myb1 membrane trafficking protein (Target of Myb protein 1) | 5 | UniProt NCBI |
| CUEDC1 | CUE domain-containing protein 1 | 3 | UniProt NCBI |
| TOM1L1 | TOM1-like protein 1 (Src-activating and signaling molecule protein) (Target of Myb-like protein 1) | 5 | UniProt NCBI |
| TOLLIP | Toll-interacting protein | 5 | UniProt NCBI |
| TOM1L2 | TOM1-like protein 2 (Target of Myb-like protein 2) | 5 | UniProt NCBI |
| PLAC9 | Placenta-specific protein 9 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030276 | 0.0219369042126 | 0.5 | TOM1 TOM1L2 TOM1L1 | clathrin binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TOLLIP | TOM1 | 0.999 | 0.516 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| TOM1L2 | CUEDC1 | 0.997 | 0.03 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TOM1L2 | TOLLIP | 0.995 | 0.154 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
| TOLLIP | TOM1L1 | 0.995 | 0.056 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| CUEDC1 | TOM1 | 0.995 | 0.068 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TOM1L1 | CUEDC1 | 0.986 | 0.082 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PLAC9 | CUEDC1 | 0.963 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TOLLIP | CUEDC1 | 0.941 | 0.09 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TOM1L2 | TOM1 | 0.895 | 0.14 |
mutually_exclusive (Q9H0E2)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TOM1L1 | TOM1 | 0.821 | 0.03 |
mutually_exclusive (Q9H0E2)
|
bioplex3_WMM gupta_WMM WMM_only |
| TOM1L2 | TOM1L1 | 0.789 | 0.08 |
mutually_exclusive (Q9H0E2)
|
bioplex3_WMM WMM_only |
| TOM1L2 | PLAC9 | 0.018 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TOLLIP | PLAC9 | 0.015 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PLAC9 | TOM1 | 0.013 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes